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The map label for this gene is trkH [H]

Identifier: 150006270

GI number: 150006270

Start: 4667380

End: 4668888

Strand: Reverse

Name: trkH [H]

Synonym: BVU_3781

Alternate gene names: 150006270

Gene position: 4668888-4667380 (Counterclockwise)

Preceding gene: 150006274

Following gene: 150006269

Centisome position: 90.43

GC content: 40.16

Gene sequence:

>1509_bases
ATGGGAGAATTTTATAATCCAGATAAATTATATAAAGGTGGAAGCCGGAATAATAGCTTGATAAATAAAAAAATGATATT
CCGTGTATTGGGGGTATTACTTTTTATTGAATCTGCTATGTTCCTGCTTTGTGCGGCTGTTTCCTTATGTTACGGTGAGC
AAGATTATCAATATTTTCTATATACCATTCTTTTGAATACATTGGTCGGTGGAGTTTTGCTAATTTGTAGTAGAGGTGCT
GAGAATCGGCTGACACGACGAGATGGGTACTGCATTGTAACTTTTACTTGGTTTTTGTTTACGTTGTTTGGAATGTTGCC
TTTTTATTTTAGTGGAGGAATCCCTTCGGTGACGGATGCCTTTTTTGAAACCATGTCGGGTTTTACTACTACAGGAGCTA
CTATATTGGATGATATAGAATCTCTTTCACATGGTCTGTTATTTTGGCGTAGCTTGACACAATGGATAGGTGGCTTGGGT
ATTGTCTTTTTTACTATTGCTGTGCTTCCTATTTTCGGGGGAGGAACTATACAACTTTTTTCAGCTGAGGCTATCGGGGT
GACGCACGACAAAACACATCCCCGGATTGATGTGATGGCTAAGTGGCTGTGGATGATATATGCTATTCTTACAATTGCAG
AAACTGTGCTGCTGATGATAGGAGGAATGAGTTTTTTTGATGCGGTATGTCATTCATTCTCAACAACGGCTACAGGTGGT
TATTCTACCAAACAAGCTAGTGTAGCTTATTGGAACTCTCCGTTTATAGAATATGTAATAGCGATATTTATGATCCTTTC
GGGTATTAATTTCTCTCTCTATTTTATGTGTCTGAAAGGGAAAGGCAAGCGTTTATTTCAGGATGATGAATTCCGTTGGT
TTATGAAATCAGTGAGTATTCTGACACTTGTTATTACGTTTGCCTTAGTTTTTCAGAATCATTATGATTGGGAAAAGGCA
TTCCGCAGGGCTCTGTTTCAAGTAGCTACGGCGCATACGTCATGCGGCTTTGCAACGGATGATTATAACTTGTGGCCATC
TTTTACATGGATGCTTCTTATTTTTGCTATGTTGTCAGGTGGATGTACGGGGTCTACTAGTGGGGGAATCAAAAATATGC
GCCTTATGATTCTGGCGCGTAATATCAAAAATGAATTCAAACGGATGCTGCATCCTAGGGCTGTATTGCCTGTTCGTGTG
AACCGTCAGGTTATATCGCCTTCCATCATTGCTTCAGTGAATACATTCTTTGTATTTTATTTGTTCTGTATTTTGGCCGG
ATGGATACTGCTGATGTTTTTCGGGGTGGGGATAATTGAAGCGATGAGTACAGTAATTTCTAGCTTAGGCAATGTGGGAC
CGGGGCTAGGAGCATTCGGTCCTGCTTTTTCATGGGCGGCGTTGCCTGATGCTGCTAAATGGATATTGTCGTTCCTGATG
TTGATAGGACGTTTGGAATTGTTTGCTGTGTTGTTGCTTTTTTATTCAGGATTTTGGGAAAGACGATAG

Upstream 100 bases:

>100_bases
TTCATATAATATCTGTTTGTTTATCAATAGTTTATAATGTTGTTTTTCATTTTGGCATAGTATTCGCTATATACTTGTCG
AATATAAAAGGTATAAAAAG

Downstream 100 bases:

>100_bases
TTCTCCGGGAAAAATTGATATGTATCATTTAATTAATGGGTATTCATTGAAATGAAGTTCTAGAAATATGTATTTTTACA
AAGGATGATATATATTTGTG

Product: Trk system K+ uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MGEFYNPDKLYKGGSRNNSLINKKMIFRVLGVLLFIESAMFLLCAAVSLCYGEQDYQYFLYTILLNTLVGGVLLICSRGA
ENRLTRRDGYCIVTFTWFLFTLFGMLPFYFSGGIPSVTDAFFETMSGFTTTGATILDDIESLSHGLLFWRSLTQWIGGLG
IVFFTIAVLPIFGGGTIQLFSAEAIGVTHDKTHPRIDVMAKWLWMIYAILTIAETVLLMIGGMSFFDAVCHSFSTTATGG
YSTKQASVAYWNSPFIEYVIAIFMILSGINFSLYFMCLKGKGKRLFQDDEFRWFMKSVSILTLVITFALVFQNHYDWEKA
FRRALFQVATAHTSCGFATDDYNLWPSFTWMLLIFAMLSGGCTGSTSGGIKNMRLMILARNIKNEFKRMLHPRAVLPVRV
NRQVISPSIIASVNTFFVFYLFCILAGWILLMFFGVGIIEAMSTVISSLGNVGPGLGAFGPAFSWAALPDAAKWILSFLM
LIGRLELFAVLLLFYSGFWERR

Sequences:

>Translated_502_residues
MGEFYNPDKLYKGGSRNNSLINKKMIFRVLGVLLFIESAMFLLCAAVSLCYGEQDYQYFLYTILLNTLVGGVLLICSRGA
ENRLTRRDGYCIVTFTWFLFTLFGMLPFYFSGGIPSVTDAFFETMSGFTTTGATILDDIESLSHGLLFWRSLTQWIGGLG
IVFFTIAVLPIFGGGTIQLFSAEAIGVTHDKTHPRIDVMAKWLWMIYAILTIAETVLLMIGGMSFFDAVCHSFSTTATGG
YSTKQASVAYWNSPFIEYVIAIFMILSGINFSLYFMCLKGKGKRLFQDDEFRWFMKSVSILTLVITFALVFQNHYDWEKA
FRRALFQVATAHTSCGFATDDYNLWPSFTWMLLIFAMLSGGCTGSTSGGIKNMRLMILARNIKNEFKRMLHPRAVLPVRV
NRQVISPSIIASVNTFFVFYLFCILAGWILLMFFGVGIIEAMSTVISSLGNVGPGLGAFGPAFSWAALPDAAKWILSFLM
LIGRLELFAVLLLFYSGFWERR
>Mature_501_residues
GEFYNPDKLYKGGSRNNSLINKKMIFRVLGVLLFIESAMFLLCAAVSLCYGEQDYQYFLYTILLNTLVGGVLLICSRGAE
NRLTRRDGYCIVTFTWFLFTLFGMLPFYFSGGIPSVTDAFFETMSGFTTTGATILDDIESLSHGLLFWRSLTQWIGGLGI
VFFTIAVLPIFGGGTIQLFSAEAIGVTHDKTHPRIDVMAKWLWMIYAILTIAETVLLMIGGMSFFDAVCHSFSTTATGGY
STKQASVAYWNSPFIEYVIAIFMILSGINFSLYFMCLKGKGKRLFQDDEFRWFMKSVSILTLVITFALVFQNHYDWEKAF
RRALFQVATAHTSCGFATDDYNLWPSFTWMLLIFAMLSGGCTGSTSGGIKNMRLMILARNIKNEFKRMLHPRAVLPVRVN
RQVISPSIIASVNTFFVFYLFCILAGWILLMFFGVGIIEAMSTVISSLGNVGPGLGAFGPAFSWAALPDAAKWILSFLML
IGRLELFAVLLLFYSGFWERR

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=482, Percent_Identity=38.5892116182573, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI1787626, Length=480, Percent_Identity=34.1666666666667, Blast_Score=279, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 56373; Mature: 56242

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEFYNPDKLYKGGSRNNSLINKKMIFRVLGVLLFIESAMFLLCAAVSLCYGEQDYQYFL
CCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YTILLNTLVGGVLLICSRGAENRLTRRDGYCIVTFTWFLFTLFGMLPFYFSGGIPSVTDA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHH
FFETMSGFTTTGATILDDIESLSHGLLFWRSLTQWIGGLGIVFFTIAVLPIFGGGTIQLF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SAEAIGVTHDKTHPRIDVMAKWLWMIYAILTIAETVLLMIGGMSFFDAVCHSFSTTATGG
ECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC
YSTKQASVAYWNSPFIEYVIAIFMILSGINFSLYFMCLKGKGKRLFQDDEFRWFMKSVSI
CCCCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHH
LTLVITFALVFQNHYDWEKAFRRALFQVATAHTSCGFATDDYNLWPSFTWMLLIFAMLSG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GCTGSTSGGIKNMRLMILARNIKNEFKRMLHPRAVLPVRVNRQVISPSIIASVNTFFVFY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHCHHHHHHHHHHHHHH
LFCILAGWILLMFFGVGIIEAMSTVISSLGNVGPGLGAFGPAFSWAALPDAAKWILSFLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHH
LIGRLELFAVLLLFYSGFWERR
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GEFYNPDKLYKGGSRNNSLINKKMIFRVLGVLLFIESAMFLLCAAVSLCYGEQDYQYFL
CCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YTILLNTLVGGVLLICSRGAENRLTRRDGYCIVTFTWFLFTLFGMLPFYFSGGIPSVTDA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHH
FFETMSGFTTTGATILDDIESLSHGLLFWRSLTQWIGGLGIVFFTIAVLPIFGGGTIQLF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SAEAIGVTHDKTHPRIDVMAKWLWMIYAILTIAETVLLMIGGMSFFDAVCHSFSTTATGG
ECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC
YSTKQASVAYWNSPFIEYVIAIFMILSGINFSLYFMCLKGKGKRLFQDDEFRWFMKSVSI
CCCCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHH
LTLVITFALVFQNHYDWEKAFRRALFQVATAHTSCGFATDDYNLWPSFTWMLLIFAMLSG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GCTGSTSGGIKNMRLMILARNIKNEFKRMLHPRAVLPVRVNRQVISPSIIASVNTFFVFY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHCHHHHHHHHHHHHHH
LFCILAGWILLMFFGVGIIEAMSTVISSLGNVGPGLGAFGPAFSWAALPDAAKWILSFLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHH
LIGRLELFAVLLLFYSGFWERR
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]