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The map label for this gene is ttcA [H]

Identifier: 150006134

GI number: 150006134

Start: 4512567

End: 4513322

Strand: Reverse

Name: ttcA [H]

Synonym: BVU_3645

Alternate gene names: 150006134

Gene position: 4513322-4512567 (Counterclockwise)

Preceding gene: 150006141

Following gene: 150006132

Centisome position: 87.41

GC content: 39.42

Gene sequence:

>756_bases
ATGGCACAATTTACGGAAGACGAGAAAATAATGCGAAGGTTGGAGCAACGCTTTAACAAGGGGGTGGTAAAGTATCGCTT
GATTGAGGATGGTGATAAAATTTTGATAGGTCTTTCTGGTGGGAAGGATTCTTTGGCTCTGTTGGAGCTATTGGCAAGGC
GTTCACGTATTTTGAAACCGAAATTTACAGTGATAGCTGTGCATGTAGGCATGACAAATATTCCTTATCAATCTGATTTG
GAATATCTGAAAGGCTACTCAGAGGATTTAGGGGTGCCGTTTGTGCATTATGAAACTTTTTTTGATCCGAGTACCGACAC
TCGGAAGTCTCCTTGTTTCCTTTGTTCTTGGAATCGGAGAAAAGCTTTGTTCACGGTGGCAAAGGAGCAGGGGTGCAATA
AGATTGCTTTAGGACATCATATGGATGATATCTTGGAAACTTTGTTGATGAATATTACTTTTCAGGGAGCCTTCAGTACA
ATGCCTCCTAAATTAGTGATGCGTAAATTTGAGATGACAATTATTCGTCCGATGTGCTTGGTACATGAAGCGGATTTAAT
TGAAATGGCACGTATCCGCGGTTTTCGTAAACAGATCAAAGATTGTCCTTATGAAAGTTTGTCGAATCGTTCAAATATGA
AAGAGGTTTTATATTCTCTAGAAAAAATGAATCCTGAAGCACGGTATAGTTTGTGGAAATGCATGACAAATATTCAGGAA
GAATTGTTGCCTGGGATGAATGAACACGATTTATAG

Upstream 100 bases:

>100_bases
ATTAATTGGAATTCTCATGCTTCACATAATTCTATTTTGTTAAATCTTCCATAAATCATTCTTTTCATGTACTTTTGTGC
CCTATTTTTAAAGAAGATGT

Downstream 100 bases:

>100_bases
TGGATATGGTTGTTTTGTTATTAGGGGATATAACGAAACTGCTTATAGTTAGTTGTTTGTACTTGTGTGCAGCTTAACCA
ACTATCAATATTATTAATGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAQFTEDEKIMRRLEQRFNKGVVKYRLIEDGDKILIGLSGGKDSLALLELLARRSRILKPKFTVIAVHVGMTNIPYQSDL
EYLKGYSEDLGVPFVHYETFFDPSTDTRKSPCFLCSWNRRKALFTVAKEQGCNKIALGHHMDDILETLLMNITFQGAFST
MPPKLVMRKFEMTIIRPMCLVHEADLIEMARIRGFRKQIKDCPYESLSNRSNMKEVLYSLEKMNPEARYSLWKCMTNIQE
ELLPGMNEHDL

Sequences:

>Translated_251_residues
MAQFTEDEKIMRRLEQRFNKGVVKYRLIEDGDKILIGLSGGKDSLALLELLARRSRILKPKFTVIAVHVGMTNIPYQSDL
EYLKGYSEDLGVPFVHYETFFDPSTDTRKSPCFLCSWNRRKALFTVAKEQGCNKIALGHHMDDILETLLMNITFQGAFST
MPPKLVMRKFEMTIIRPMCLVHEADLIEMARIRGFRKQIKDCPYESLSNRSNMKEVLYSLEKMNPEARYSLWKCMTNIQE
ELLPGMNEHDL
>Mature_250_residues
AQFTEDEKIMRRLEQRFNKGVVKYRLIEDGDKILIGLSGGKDSLALLELLARRSRILKPKFTVIAVHVGMTNIPYQSDLE
YLKGYSEDLGVPFVHYETFFDPSTDTRKSPCFLCSWNRRKALFTVAKEQGCNKIALGHHMDDILETLLMNITFQGAFSTM
PPKLVMRKFEMTIIRPMCLVHEADLIEMARIRGFRKQIKDCPYESLSNRSNMKEVLYSLEKMNPEARYSLWKCMTNIQEE
LLPGMNEHDL

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=235, Percent_Identity=31.4893617021277, Blast_Score=117, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI193211090, Length=219, Percent_Identity=29.2237442922374, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17540090, Length=238, Percent_Identity=25.2100840336134, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651972, Length=228, Percent_Identity=28.0701754385965, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 29155; Mature: 29023

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFTEDEKIMRRLEQRFNKGVVKYRLIEDGDKILIGLSGGKDSLALLELLARRSRILKP
CCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCC
KFTVIAVHVGMTNIPYQSDLEYLKGYSEDLGVPFVHYETFFDPSTDTRKSPCFLCSWNRR
CEEEEEEEECCCCCCCHHHHHHHCCCCHHCCCCEEEEEEEECCCCCCCCCCEEEEECCCC
KALFTVAKEQGCNKIALGHHMDDILETLLMNITFQGAFSTMPPKLVMRKFEMTIIRPMCL
HHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
VHEADLIEMARIRGFRKQIKDCPYESLSNRSNMKEVLYSLEKMNPEARYSLWKCMTNIQE
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ELLPGMNEHDL
HHCCCCCCCCC
>Mature Secondary Structure 
AQFTEDEKIMRRLEQRFNKGVVKYRLIEDGDKILIGLSGGKDSLALLELLARRSRILKP
CCCCHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCC
KFTVIAVHVGMTNIPYQSDLEYLKGYSEDLGVPFVHYETFFDPSTDTRKSPCFLCSWNRR
CEEEEEEEECCCCCCCHHHHHHHCCCCHHCCCCEEEEEEEECCCCCCCCCCEEEEECCCC
KALFTVAKEQGCNKIALGHHMDDILETLLMNITFQGAFSTMPPKLVMRKFEMTIIRPMCL
HHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
VHEADLIEMARIRGFRKQIKDCPYESLSNRSNMKEVLYSLEKMNPEARYSLWKCMTNIQE
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ELLPGMNEHDL
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA