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The map label for this gene is kdsA [H]

Identifier: 150006073

GI number: 150006073

Start: 4445032

End: 4445829

Strand: Reverse

Name: kdsA [H]

Synonym: BVU_3582

Alternate gene names: 150006073

Gene position: 4445829-4445032 (Counterclockwise)

Preceding gene: 150006074

Following gene: 150006069

Centisome position: 86.11

GC content: 44.99

Gene sequence:

>798_bases
ATGACAATTTCAGATTTAAGAAAGACAGATAATTTCTTTTTACTGGCTGGTCCTTGTGTGATCGAAGGAGAGGAAATGGC
TCTCCGAATAGCAGATCGTATTGTGAAAATAACAGATAAACTGGGTATTCCCTATGTGTTTAAAGGATCTTATCGTAAGG
CTAACCGTTCCCGTTTGGATTCGTTTACAGGAATAGGTGATGAAAAGGCCTTGAAAGTACTTCGTAAAGTACGGGAAACT
TTTGGAATTCCTGTGGTAACCGATATTCATAGTGCTGGAGAAGCTGCTATGGCCGCTGAATATGTGGATGTGTTGCAGAT
TCCTGCTTTCCTGTGTCGCCAGACTGATTTGCTGGTGGCGGCAGCTCATACCGGAAAGATTGTCAACATCAAGAAAGGAC
AATTTTTATCACCTGGCGCCATGCGTTTTGCTGCTGACAAAGTGGTGGAGGCGGGTAATGATCAGGTTATGCTGACCGAG
CGGGGAACGACTTTCGGGTATCAGGATTTGATTGTAGATTATCGGGGTATTCCGGAAATGCAGACTTTAGGTTTTCCTGT
AATTCTGGATGTGACACATTCTTTGCAACAACCTAATCAGACTGCCGGTGTGACAGGTGGTATGCCGCAGCTTATTGAAA
CGGTAGCCAAGGCTGGCATAGCGGTAGGAGTGGACGGTTTGTTTATGGAAACCCACGAAGACCCTTCTGTCGCTAAGAGT
GACGGAGCGAATATGTTGAAACTGGATTTGCTGGAAGGGCTATTGACCAAACTGGTAAGAATCCGCCAAGTGTTATAA

Upstream 100 bases:

>100_bases
AGCTATAACTTTGATTATCCCTAATTAAAAACTATAGATATCCATTTCTTGCTTTAAGGATAGAGGCAGAGTAGATATCT
CAATGAATAGACGTAAGATA

Downstream 100 bases:

>100_bases
ATGTTATTCGTTGGGGATTCACAGGTAAGATGGGTTAATTTATTTGGACTATGGGGCAACTTGCATGAATAGTATAAAAT
AAGGTCGGTTTTTGCAGTAG

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTISDLRKTDNFFLLAGPCVIEGEEMALRIADRIVKITDKLGIPYVFKGSYRKANRSRLDSFTGIGDEKALKVLRKVRET
FGIPVVTDIHSAGEAAMAAEYVDVLQIPAFLCRQTDLLVAAAHTGKIVNIKKGQFLSPGAMRFAADKVVEAGNDQVMLTE
RGTTFGYQDLIVDYRGIPEMQTLGFPVILDVTHSLQQPNQTAGVTGGMPQLIETVAKAGIAVGVDGLFMETHEDPSVAKS
DGANMLKLDLLEGLLTKLVRIRQVL

Sequences:

>Translated_265_residues
MTISDLRKTDNFFLLAGPCVIEGEEMALRIADRIVKITDKLGIPYVFKGSYRKANRSRLDSFTGIGDEKALKVLRKVRET
FGIPVVTDIHSAGEAAMAAEYVDVLQIPAFLCRQTDLLVAAAHTGKIVNIKKGQFLSPGAMRFAADKVVEAGNDQVMLTE
RGTTFGYQDLIVDYRGIPEMQTLGFPVILDVTHSLQQPNQTAGVTGGMPQLIETVAKAGIAVGVDGLFMETHEDPSVAKS
DGANMLKLDLLEGLLTKLVRIRQVL
>Mature_264_residues
TISDLRKTDNFFLLAGPCVIEGEEMALRIADRIVKITDKLGIPYVFKGSYRKANRSRLDSFTGIGDEKALKVLRKVRETF
GIPVVTDIHSAGEAAMAAEYVDVLQIPAFLCRQTDLLVAAAHTGKIVNIKKGQFLSPGAMRFAADKVVEAGNDQVMLTER
GTTFGYQDLIVDYRGIPEMQTLGFPVILDVTHSLQQPNQTAGVTGGMPQLIETVAKAGIAVGVDGLFMETHEDPSVAKSD
GANMLKLDLLEGLLTKLVRIRQVL

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=265, Percent_Identity=44.1509433962264, Blast_Score=232, Evalue=2e-62,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 28834; Mature: 28703

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISDLRKTDNFFLLAGPCVIEGEEMALRIADRIVKITDKLGIPYVFKGSYRKANRSRLD
CCHHHHHCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHH
SFTGIGDEKALKVLRKVRETFGIPVVTDIHSAGEAAMAAEYVDVLQIPAFLCRQTDLLVA
HHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
AAHTGKIVNIKKGQFLSPGAMRFAADKVVEAGNDQVMLTERGTTFGYQDLIVDYRGIPEM
EECCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCCH
QTLGFPVILDVTHSLQQPNQTAGVTGGMPQLIETVAKAGIAVGVDGLFMETHEDPSVAKS
HHCCCCEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCEEEECCCCCCCHHC
DGANMLKLDLLEGLLTKLVRIRQVL
CCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TISDLRKTDNFFLLAGPCVIEGEEMALRIADRIVKITDKLGIPYVFKGSYRKANRSRLD
CHHHHHCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHH
SFTGIGDEKALKVLRKVRETFGIPVVTDIHSAGEAAMAAEYVDVLQIPAFLCRQTDLLVA
HHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
AAHTGKIVNIKKGQFLSPGAMRFAADKVVEAGNDQVMLTERGTTFGYQDLIVDYRGIPEM
EECCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCCH
QTLGFPVILDVTHSLQQPNQTAGVTGGMPQLIETVAKAGIAVGVDGLFMETHEDPSVAKS
HHCCCCEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCEEEECCCCCCCHHC
DGANMLKLDLLEGLLTKLVRIRQVL
CCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA