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The map label for this gene is lspA [H]

Identifier: 150005576

GI number: 150005576

Start: 3874551

End: 3875189

Strand: Direct

Name: lspA [H]

Synonym: BVU_3061

Alternate gene names: 150005576

Gene position: 3874551-3875189 (Clockwise)

Preceding gene: 150005575

Following gene: 150005577

Centisome position: 75.04

GC content: 37.56

Gene sequence:

>639_bases
ATGAAGAAACTACTCACCAAAGGGCAGCTCTCTGTTCTTATCGTCTTTGCAGTTCTGATTATCGACCAGATAATAAAGAT
ATTGGTAAAGACCAATATGTACTGGCATGAGAGTATCCGCATAACAGATTGGTTTTATATCTATTTTACAGAAAATAACG
GCATGGCTTTCGGTATGGAAATATTCGGAAAGTTATTCCTTACTACCTTCCGTATTGTAGCTGTGGGATTGATTATCTGG
TATCTGGCAAAAATAGTGAAACAGAATTATAAGACTGGTTATATTGTATGTATCTCTTTAATTTTGGCAGGGGCTATCGG
TAATATTATAGACAGTGTGTTCTATGGCGTTGTTTTTAATGAAAGTACTCATAGTACCATCGCTTCTTTTGTTCCGGTAG
GTGAAGGGTATTCGGAATGGTTGCATGGTAAGGTGGTGGATATGTTCTATTTTCCCATTATTGAAACCAACTGGCCCGAA
TGGATACCGGGAATAGGAGGGGAACATTTCATATTTTTCAGTCCGATATTTAATTTTGCCGATGCTGCCATCAGTTGCGG
TATTGTGGCGTTGTTGTTATTTTACGGTAAGTATCTGAATAAGAATATTCACCCGTCAGCAGAAGAAATTAAAGAATAA

Upstream 100 bases:

>100_bases
TAATGGTTAGTGATTAATAGTTAATGAGTTTCACTGTCATGTTACAGTATTAACCGCTAACGGCTAATCATTAACCATTA
ATTAATTTTCAATTTAATAA

Downstream 100 bases:

>100_bases
ATGATGCGTCGCAGGAATATTACTTGGGTGTGGCTGCTGGGTGCGGCTTTTATGGTGGGGTGTGGCAAGCAAGTGCCTGA
AGATATTATCCAGCCGGACA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKKLLTKGQLSVLIVFAVLIIDQIIKILVKTNMYWHESIRITDWFYIYFTENNGMAFGMEIFGKLFLTTFRIVAVGLIIW
YLAKIVKQNYKTGYIVCISLILAGAIGNIIDSVFYGVVFNESTHSTIASFVPVGEGYSEWLHGKVVDMFYFPIIETNWPE
WIPGIGGEHFIFFSPIFNFADAAISCGIVALLLFYGKYLNKNIHPSAEEIKE

Sequences:

>Translated_212_residues
MKKLLTKGQLSVLIVFAVLIIDQIIKILVKTNMYWHESIRITDWFYIYFTENNGMAFGMEIFGKLFLTTFRIVAVGLIIW
YLAKIVKQNYKTGYIVCISLILAGAIGNIIDSVFYGVVFNESTHSTIASFVPVGEGYSEWLHGKVVDMFYFPIIETNWPE
WIPGIGGEHFIFFSPIFNFADAAISCGIVALLLFYGKYLNKNIHPSAEEIKE
>Mature_212_residues
MKKLLTKGQLSVLIVFAVLIIDQIIKILVKTNMYWHESIRITDWFYIYFTENNGMAFGMEIFGKLFLTTFRIVAVGLIIW
YLAKIVKQNYKTGYIVCISLILAGAIGNIIDSVFYGVVFNESTHSTIASFVPVGEGYSEWLHGKVVDMFYFPIIETNWPE
WIPGIGGEHFIFFSPIFNFADAAISCGIVALLLFYGKYLNKNIHPSAEEIKE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 24149; Mature: 24149

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLTKGQLSVLIVFAVLIIDQIIKILVKTNMYWHESIRITDWFYIYFTENNGMAFGME
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEEEEEEEEECCCCCEEHHH
IFGKLFLTTFRIVAVGLIIWYLAKIVKQNYKTGYIVCISLILAGAIGNIIDSVFYGVVFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ESTHSTIASFVPVGEGYSEWLHGKVVDMFYFPIIETNWPEWIPGIGGEHFIFFSPIFNFA
CCHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECHHHHHH
DAAISCGIVALLLFYGKYLNKNIHPSAEEIKE
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MKKLLTKGQLSVLIVFAVLIIDQIIKILVKTNMYWHESIRITDWFYIYFTENNGMAFGME
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEEEEEEEEECCCCCEEHHH
IFGKLFLTTFRIVAVGLIIWYLAKIVKQNYKTGYIVCISLILAGAIGNIIDSVFYGVVFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ESTHSTIASFVPVGEGYSEWLHGKVVDMFYFPIIETNWPEWIPGIGGEHFIFFSPIFNFA
CCHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECHHHHHH
DAAISCGIVALLLFYGKYLNKNIHPSAEEIKE
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA