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The map label for this gene is dtpA [H]

Identifier: 150005563

GI number: 150005563

Start: 3857583

End: 3859244

Strand: Direct

Name: dtpA [H]

Synonym: BVU_3048

Alternate gene names: 150005563

Gene position: 3857583-3859244 (Clockwise)

Preceding gene: 150005562

Following gene: 150005566

Centisome position: 74.71

GC content: 47.11

Gene sequence:

>1662_bases
ATGTTTGAAGGACAGCCTAAAGGCTTATACGCATTAGCTCTCGCCAATACCGGCGAACGCTTTGGTTATTACACCATGCT
TGCTATTTTCACTCTCTTCCTGCAAGCGAAATTCGGCTTTACAGCCGCCACGACGTCAACAATCTTTGCCAGTTTCCTGG
CAGGAGTGTATTTCATGCCGCTTATCGGAGGTATCCTGGCCGATAAATTCGGTTATGGCAAGATGGTTACTACCGGTATC
GTTATCATGTTTGCCGGTTATGTGCTGCTGGCTATCCCGATGGCAACCAATATCGGATTGTATTCCATGTTCGGCGCTCT
TGCCCTGATTGCTTTGGGAACCGGACTTTTCAAGGGAAATCTGCAAGTAATGGTAGGTAATCTGTATGATGCTCCTGAGT
ATAGCGCGAAACGTGATACCGCTTTCAGTTTGTTCTATATGGCAATCAACATCGGCGCCCTGTTCGCTCCGACTGCCGCT
ACTGCCATGACCAACTATGTGTTGGGCAAAGCAGGCTTCAGCTATGTGCCCCAGATACCTTCTTTGGCACACCAGTTCCT
GGACGGTACGATTACCGCCGAAGGTGAGGCCACACTGACTGCCATGCAGACCGCACAGAATTTCACAGGAAGTATGGCTG
ATTTCTGTACTACCTATATTGATAAATTGTCTGAAGCCTATAATTATGGTTTCGGTGTAGCTTGTATCTCACTGGTTGCC
TCTATGGCTATTTATGTTATTTTCCGTTCTACATTCAAACATGCCGATTACAACTCCAAGCAGGCTAAACCGGCCAATGT
ACACGAAGAAGAGCTGACTCCCGCACAGACCAAAGAACGCATCGTCGCTTTGTTACTGGTATTCGCTGTGGTTATTTTCT
TCTGGATGGCATTCCATCAGAACGGTCTTACCATGACCTTCTTCGCCCGTGACTACACGGCACATGAGGTAACCGGTCTG
GATCGCCTTGGCTTCAGCGTATGGAATCTGGCTCTGCTTATTGTAACCGTTTATGCAGGTTTCTCACTGTTCCAGTCCAA
GACAGGCAAGGGCAAATTGATTTCAGGCGTTATTGCTACCTTGGCTCTTGTGGTTTTAGGAGTCAATTATGGTACTATGG
ACCCTACATTGCCTATCCTTCCTCAGATTTTCCAACAGTTTAACCCCTTCTTCGTTGTCGCTCTGACTCCGGTATCACTG
GCAGTATTCGGTTCATTGGCAAAGAAAGGAAAAGAGCCATCAGCTCCGCGTAAAATCGGTATCGGTATGGTGATTGCCGC
AGTAGGTTTCATGTTGCTGGCATTCGGCTCATTCGGTCTGCCTACTCCTGCCGAAGTAGAAGCCAATGGTATTGCCGAGA
GCGCGTTGGTTTCACCCAACTGGCTGATCTCGACTTATCTGGTATTGACTTTTGCCGAATTGTTCCTGTCACCGATGGGT
ATCTCATTTGTTTCCAAGGTAGCTCCTCCCAAGTATAAAGGCGCTATGATGGGACTTTGGTTTGTGGCTACTGCTATTGG
TAACTATCTGGTAGCTATCATCGGTTATTTGTGGGGTGATATGCAGTTGTGGATGGTATGGAGTGTATTGATTGTGTGCT
GCTTGCTTTCCGCATTGTTCATCTTCTCTATCATGAAGAAACTGGAAAAGGTTGCGAAATAA

Upstream 100 bases:

>100_bases
CAAAAAGAGTCACATTTGTGGCTCTTTTTTTTTCAGATAGACTAAAAGTTATATCTTTGCAAAAAAAGAATACTAACTAT
TAATTAAATCTTTATCAACT

Downstream 100 bases:

>100_bases
TTCCCGCCTATATTATATATGAAAAAGAAGCCCGCTTAACCAATCAAGCGGGCTTCTCTTTTTTTATAAATTACAGAAGA
AGGATACGAAAACAGGAACA

Product: putative H+/peptide symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MFEGQPKGLYALALANTGERFGYYTMLAIFTLFLQAKFGFTAATTSTIFASFLAGVYFMPLIGGILADKFGYGKMVTTGI
VIMFAGYVLLAIPMATNIGLYSMFGALALIALGTGLFKGNLQVMVGNLYDAPEYSAKRDTAFSLFYMAINIGALFAPTAA
TAMTNYVLGKAGFSYVPQIPSLAHQFLDGTITAEGEATLTAMQTAQNFTGSMADFCTTYIDKLSEAYNYGFGVACISLVA
SMAIYVIFRSTFKHADYNSKQAKPANVHEEELTPAQTKERIVALLLVFAVVIFFWMAFHQNGLTMTFFARDYTAHEVTGL
DRLGFSVWNLALLIVTVYAGFSLFQSKTGKGKLISGVIATLALVVLGVNYGTMDPTLPILPQIFQQFNPFFVVALTPVSL
AVFGSLAKKGKEPSAPRKIGIGMVIAAVGFMLLAFGSFGLPTPAEVEANGIAESALVSPNWLISTYLVLTFAELFLSPMG
ISFVSKVAPPKYKGAMMGLWFVATAIGNYLVAIIGYLWGDMQLWMVWSVLIVCCLLSALFIFSIMKKLEKVAK

Sequences:

>Translated_553_residues
MFEGQPKGLYALALANTGERFGYYTMLAIFTLFLQAKFGFTAATTSTIFASFLAGVYFMPLIGGILADKFGYGKMVTTGI
VIMFAGYVLLAIPMATNIGLYSMFGALALIALGTGLFKGNLQVMVGNLYDAPEYSAKRDTAFSLFYMAINIGALFAPTAA
TAMTNYVLGKAGFSYVPQIPSLAHQFLDGTITAEGEATLTAMQTAQNFTGSMADFCTTYIDKLSEAYNYGFGVACISLVA
SMAIYVIFRSTFKHADYNSKQAKPANVHEEELTPAQTKERIVALLLVFAVVIFFWMAFHQNGLTMTFFARDYTAHEVTGL
DRLGFSVWNLALLIVTVYAGFSLFQSKTGKGKLISGVIATLALVVLGVNYGTMDPTLPILPQIFQQFNPFFVVALTPVSL
AVFGSLAKKGKEPSAPRKIGIGMVIAAVGFMLLAFGSFGLPTPAEVEANGIAESALVSPNWLISTYLVLTFAELFLSPMG
ISFVSKVAPPKYKGAMMGLWFVATAIGNYLVAIIGYLWGDMQLWMVWSVLIVCCLLSALFIFSIMKKLEKVAK
>Mature_553_residues
MFEGQPKGLYALALANTGERFGYYTMLAIFTLFLQAKFGFTAATTSTIFASFLAGVYFMPLIGGILADKFGYGKMVTTGI
VIMFAGYVLLAIPMATNIGLYSMFGALALIALGTGLFKGNLQVMVGNLYDAPEYSAKRDTAFSLFYMAINIGALFAPTAA
TAMTNYVLGKAGFSYVPQIPSLAHQFLDGTITAEGEATLTAMQTAQNFTGSMADFCTTYIDKLSEAYNYGFGVACISLVA
SMAIYVIFRSTFKHADYNSKQAKPANVHEEELTPAQTKERIVALLLVFAVVIFFWMAFHQNGLTMTFFARDYTAHEVTGL
DRLGFSVWNLALLIVTVYAGFSLFQSKTGKGKLISGVIATLALVVLGVNYGTMDPTLPILPQIFQQFNPFFVVALTPVSL
AVFGSLAKKGKEPSAPRKIGIGMVIAAVGFMLLAFGSFGLPTPAEVEANGIAESALVSPNWLISTYLVLTFAELFLSPMG
ISFVSKVAPPKYKGAMMGLWFVATAIGNYLVAIIGYLWGDMQLWMVWSVLIVCCLLSALFIFSIMKKLEKVAK

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790572, Length=523, Percent_Identity=24.0917782026769, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789911, Length=522, Percent_Identity=22.4137931034483, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787922, Length=328, Percent_Identity=27.1341463414634, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786927, Length=157, Percent_Identity=33.7579617834395, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571098, Length=426, Percent_Identity=23.7089201877934, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571102, Length=426, Percent_Identity=24.1784037558685, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571100, Length=426, Percent_Identity=24.1784037558685, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639585, Length=144, Percent_Identity=34.0277777777778, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24639583, Length=144, Percent_Identity=34.0277777777778, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24639581, Length=144, Percent_Identity=34.0277777777778, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 59806; Mature: 59806

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEGQPKGLYALALANTGERFGYYTMLAIFTLFLQAKFGFTAATTSTIFASFLAGVYFMP
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LIGGILADKFGYGKMVTTGIVIMFAGYVLLAIPMATNIGLYSMFGALALIALGTGLFKGN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
LQVMVGNLYDAPEYSAKRDTAFSLFYMAINIGALFAPTAATAMTNYVLGKAGFSYVPQIP
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHH
SLAHQFLDGTITAEGEATLTAMQTAQNFTGSMADFCTTYIDKLSEAYNYGFGVACISLVA
HHHHHHHCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SMAIYVIFRSTFKHADYNSKQAKPANVHEEELTPAQTKERIVALLLVFAVVIFFWMAFHQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NGLTMTFFARDYTAHEVTGLDRLGFSVWNLALLIVTVYAGFSLFQSKTGKGKLISGVIAT
CCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LALVVLGVNYGTMDPTLPILPQIFQQFNPFFVVALTPVSLAVFGSLAKKGKEPSAPRKIG
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCHHHH
IGMVIAAVGFMLLAFGSFGLPTPAEVEANGIAESALVSPNWLISTYLVLTFAELFLSPMG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
ISFVSKVAPPKYKGAMMGLWFVATAIGNYLVAIIGYLWGDMQLWMVWSVLIVCCLLSALF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IFSIMKKLEKVAK
HHHHHHHHHHHCC
>Mature Secondary Structure
MFEGQPKGLYALALANTGERFGYYTMLAIFTLFLQAKFGFTAATTSTIFASFLAGVYFMP
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LIGGILADKFGYGKMVTTGIVIMFAGYVLLAIPMATNIGLYSMFGALALIALGTGLFKGN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
LQVMVGNLYDAPEYSAKRDTAFSLFYMAINIGALFAPTAATAMTNYVLGKAGFSYVPQIP
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHH
SLAHQFLDGTITAEGEATLTAMQTAQNFTGSMADFCTTYIDKLSEAYNYGFGVACISLVA
HHHHHHHCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SMAIYVIFRSTFKHADYNSKQAKPANVHEEELTPAQTKERIVALLLVFAVVIFFWMAFHQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NGLTMTFFARDYTAHEVTGLDRLGFSVWNLALLIVTVYAGFSLFQSKTGKGKLISGVIAT
CCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LALVVLGVNYGTMDPTLPILPQIFQQFNPFFVVALTPVSLAVFGSLAKKGKEPSAPRKIG
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCHHHH
IGMVIAAVGFMLLAFGSFGLPTPAEVEANGIAESALVSPNWLISTYLVLTFAELFLSPMG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
ISFVSKVAPPKYKGAMMGLWFVATAIGNYLVAIIGYLWGDMQLWMVWSVLIVCCLLSALF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IFSIMKKLEKVAK
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]