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The map label for this gene is ruvC [H]

Identifier: 150005548

GI number: 150005548

Start: 3838731

End: 3839198

Strand: Direct

Name: ruvC [H]

Synonym: BVU_3033

Alternate gene names: 150005548

Gene position: 3838731-3839198 (Clockwise)

Preceding gene: 150005547

Following gene: 150005549

Centisome position: 74.35

GC content: 40.38

Gene sequence:

>468_bases
ATGACTATGGGGGTCATTGATCTTCGTAAATATGGTGACCATTATTTAAAACTGCGCCGTATTTTTGAACGGGTGGTTGG
TATAATAGAAGCTTATTTACCTGATGAGTTAGCTATTGAGGCGCCTTTTTTTGGAAAAAATGTGCAGTCGATGTTAAAAT
TAGGGAGGGCACAGGGAGTGGCTATGGCTGCTGCTTTGAGCCGTGATATTCCTATAACAGAATATGCGCCGTTGAAGATA
AAGATGGCGATAACCGGTAATGGGCAAGCCAGCAAGGAACAGGTCGCTGATATGTTGAAAAGGATGTTACATATACCGGA
GAGTGATATGCTGCCTTTTATGGATGCAACAGATGGGTTGGCGGCTGCTTATTGTCATTATTTACAAATGGGCAGACCGA
CATTGACTAAAGAATATTCCGGCTGGAAAGATTTTATAAATAAGAATCCTGATAAAATAAAAAGATAA

Upstream 100 bases:

>100_bases
GATTCAGCCGGTAAAAGAGAAAATCATTCTGGGTATAGATCCTGGAACAACCATAATGGGGTATGGCCTGCTGAAAGTAG
TAGGTACTAAACCGCAGGTA

Downstream 100 bases:

>100_bases
GATTATGAATGTGAGACATGTTATTTGGGCATCAATTGTTTCTACTACTATTAGTTGTCAGTCTGTGAAAAAAGAATATA
ATTCGTTTGATGAATATCCT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTMGVIDLRKYGDHYLKLRRIFERVVGIIEAYLPDELAIEAPFFGKNVQSMLKLGRAQGVAMAAALSRDIPITEYAPLKI
KMAITGNGQASKEQVADMLKRMLHIPESDMLPFMDATDGLAAAYCHYLQMGRPTLTKEYSGWKDFINKNPDKIKR

Sequences:

>Translated_155_residues
MTMGVIDLRKYGDHYLKLRRIFERVVGIIEAYLPDELAIEAPFFGKNVQSMLKLGRAQGVAMAAALSRDIPITEYAPLKI
KMAITGNGQASKEQVADMLKRMLHIPESDMLPFMDATDGLAAAYCHYLQMGRPTLTKEYSGWKDFINKNPDKIKR
>Mature_154_residues
TMGVIDLRKYGDHYLKLRRIFERVVGIIEAYLPDELAIEAPFFGKNVQSMLKLGRAQGVAMAAALSRDIPITEYAPLKIK
MAITGNGQASKEQVADMLKRMLHIPESDMLPFMDATDGLAAAYCHYLQMGRPTLTKEYSGWKDFINKNPDKIKR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=90, Percent_Identity=42.2222222222222, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 17496; Mature: 17365

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMGVIDLRKYGDHYLKLRRIFERVVGIIEAYLPDELAIEAPFFGKNVQSMLKLGRAQGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHCHH
AMAAALSRDIPITEYAPLKIKMAITGNGQASKEQVADMLKRMLHIPESDMLPFMDATDGL
HHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
AAAYCHYLQMGRPTLTKEYSGWKDFINKNPDKIKR
HHHHHHHHHCCCCCHHHHCCCHHHHHCCCHHHCCC
>Mature Secondary Structure 
TMGVIDLRKYGDHYLKLRRIFERVVGIIEAYLPDELAIEAPFFGKNVQSMLKLGRAQGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHCHH
AMAAALSRDIPITEYAPLKIKMAITGNGQASKEQVADMLKRMLHIPESDMLPFMDATDGL
HHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
AAAYCHYLQMGRPTLTKEYSGWKDFINKNPDKIKR
HHHHHHHHHCCCCCHHHHCCCHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA