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The map label for this gene is basR [C]

Identifier: 150005501

GI number: 150005501

Start: 3782392

End: 3783069

Strand: Direct

Name: basR [C]

Synonym: BVU_2985

Alternate gene names: 150005501

Gene position: 3782392-3783069 (Clockwise)

Preceding gene: 150005500

Following gene: 150005502

Centisome position: 73.26

GC content: 39.68

Gene sequence:

>678_bases
ATGAAAATACTATTAGTAGAAGACGATGCTAATTTGCGTGAAGTGACTCAGCGCTCATTGGAAAAGGAGCGTTATGTGGT
GGAAATTGCTGCCGATTACCGTACCGCATTACAAAAGATAGAGGATTATGATTATGACTGCATTTTGCTGGATATTATGT
TGCCGGATGGCAGTGGCCTGGATTTGTTGGAAAAGTTGAAAGAAATGCATAAACGGGAAAATGTGATCATCCTTTCAGCC
AAAGACTCTATAGAAGACAAAGTACTAGGATTGGAGCTCGGAGCTGATGATTATCTGCCTAAACCTTTTCATTTGGTGGA
ACTGAATGCACGTATCAAAAGTGTGATACGCCGTCATCAGCAAGGTGGGGAAAATAGTATCAAATACGGAAATATAGAAA
TTTTTCCCGATAAATATGGGGTGACCGTAGCTGGAAAGAAGCTTGAACTGAACCGTAAGGAATATGATATTCTGGTTTAT
TTTATGAACCGTCCCGGCAGATTGGTTAATAAAAGCACACTTGCCGAATCCGTATGGGGCGACCATATAGATCAAGTCGA
TAATTTTGATTTTATCTATGCCCAAATCAAGAATTTACGAAAGAGATTGAAAGAGGCTGGAGCTACTCCTGAACTGAAGG
CTGTTTATGGTTTTGGATATAAAATGGTAGTGGAATAA

Upstream 100 bases:

>100_bases
TGATGGAAAAAATTGTATGGTTTCTTCGTTTTTTTTCTTATTTCAGTGTTTTTTCAGAATTATCTTGTTTCTTTGTCTTT
AAGAACCAAAAGTAGGACTT

Downstream 100 bases:

>100_bases
ATGAAACTGATTTATTATATCATTATCCGTATATCGTTGGTGTTGTCGGTTTTATTGACTGGCTGGGCCATCCTTTTCTA
TTTTGCTGTAATGGATGAGG

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKILLVEDDANLREVTQRSLEKERYVVEIAADYRTALQKIEDYDYDCILLDIMLPDGSGLDLLEKLKEMHKRENVIILSA
KDSIEDKVLGLELGADDYLPKPFHLVELNARIKSVIRRHQQGGENSIKYGNIEIFPDKYGVTVAGKKLELNRKEYDILVY
FMNRPGRLVNKSTLAESVWGDHIDQVDNFDFIYAQIKNLRKRLKEAGATPELKAVYGFGYKMVVE

Sequences:

>Translated_225_residues
MKILLVEDDANLREVTQRSLEKERYVVEIAADYRTALQKIEDYDYDCILLDIMLPDGSGLDLLEKLKEMHKRENVIILSA
KDSIEDKVLGLELGADDYLPKPFHLVELNARIKSVIRRHQQGGENSIKYGNIEIFPDKYGVTVAGKKLELNRKEYDILVY
FMNRPGRLVNKSTLAESVWGDHIDQVDNFDFIYAQIKNLRKRLKEAGATPELKAVYGFGYKMVVE
>Mature_225_residues
MKILLVEDDANLREVTQRSLEKERYVVEIAADYRTALQKIEDYDYDCILLDIMLPDGSGLDLLEKLKEMHKRENVIILSA
KDSIEDKVLGLELGADDYLPKPFHLVELNARIKSVIRRHQQGGENSIKYGNIEIFPDKYGVTVAGKKLELNRKEYDILVY
FMNRPGRLVNKSTLAESVWGDHIDQVDNFDFIYAQIKNLRKRLKEAGATPELKAVYGFGYKMVVE

Specific function: Member Of The Two-Component Regulatory System Bass/Basr. Polymyxin Resistance May Be Mediated By An Interaction Between Basr (Pmra) Or A Basr-Regulated Gene Product And Pmrd (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=35.2678571428571, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=32.4324324324324, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=36.322869955157, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=31.8385650224215, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=35.9307359307359, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=31.5555555555556, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=28, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=28.695652173913, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.004329004329, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=30.0448430493274, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=28.1938325991189, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=26.6968325791855, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788550, Length=140, Percent_Identity=31.4285714285714, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=31.0924369747899, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=116, Percent_Identity=38.7931034482759, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25926; Mature: 25926

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLVEDDANLREVTQRSLEKERYVVEIAADYRTALQKIEDYDYDCILLDIMLPDGSGL
CEEEEEECCCCHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCCCEEEEEEEECCCCCH
DLLEKLKEMHKRENVIILSAKDSIEDKVLGLELGADDYLPKPFHLVELNARIKSVIRRHQ
HHHHHHHHHHHHCCEEEEECCCCCCHHEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHH
QGGENSIKYGNIEIFPDKYGVTVAGKKLELNRKEYDILVYFMNRPGRLVNKSTLAESVWG
CCCCCCEEECCEEECCCCCCEEEECCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
DHIDQVDNFDFIYAQIKNLRKRLKEAGATPELKAVYGFGYKMVVE
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEC
>Mature Secondary Structure
MKILLVEDDANLREVTQRSLEKERYVVEIAADYRTALQKIEDYDYDCILLDIMLPDGSGL
CEEEEEECCCCHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCCCEEEEEEEECCCCCH
DLLEKLKEMHKRENVIILSAKDSIEDKVLGLELGADDYLPKPFHLVELNARIKSVIRRHQ
HHHHHHHHHHHHCCEEEEECCCCCCHHEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHH
QGGENSIKYGNIEIFPDKYGVTVAGKKLELNRKEYDILVYFMNRPGRLVNKSTLAESVWG
CCCCCCEEECCEEECCCCCCEEEECCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
DHIDQVDNFDFIYAQIKNLRKRLKEAGATPELKAVYGFGYKMVVE
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1554697 [H]