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The map label for this gene is lacZ [H]

Identifier: 150005427

GI number: 150005427

Start: 3679647

End: 3682271

Strand: Direct

Name: lacZ [H]

Synonym: BVU_2910

Alternate gene names: 150005427

Gene position: 3679647-3682271 (Clockwise)

Preceding gene: 150005426

Following gene: 150005428

Centisome position: 71.27

GC content: 49.41

Gene sequence:

>2625_bases
ATGAAGAAACTGTTTATTTTACTTGTGTGCCTGTTGCCTGTGTTGGCACAAGCTCAAATGGAAACCTCTGTAGCCGGATT
CATCCCTTTATCCGGTAGCGGAAGAATAGTATATAATTTCAATCCCGGATGGCGCTTTCATCGTGGAGACATAAAAGGCG
CGGAAGCCGTACGTTTTGATGATACATCCTGGCAGGTAGTGTCTGTTCCGCATACTGTGGAACTGATGCCTGCCGAGGCA
AGCGGTTGCCGTAACTATCAGGGTGTGGCATGGTACCGGAAACATTTTGTGATTCCTCAAGATATGAAAGGAAAAGAGGT
GTCGCTTCATTTTGAGGGAGCTATGGGAAAACAGGTGATTTATTTAAATGGCAAGAGGGTGCAAGAGCACTTGGGAGGAT
ACCTTCCTTTCACTGTGCAACTGACGGAACAGGGGGTACAGCCCGGAGACAGTTGCTTGCTGGCAGTGATGACGGATAAT
AGTGATGATAAGAATTTTCCTCCGGGAAAACGTCAATATACCTTGGATTTCGCTTATCATGGAGGAATTTACCGGGATGT
GTGGATGATAGGAAAATCAAGTGTAGCTATTACAGATGCCTTGGAGGCCGATAAGGTGGCCGGAGGTGGAGTTTTTGTGC
ATTTTGACAATATAAGCGGGAAAAAAGCGGAAGTGTATGTGGATACGGAAGTGCATAACAGTGGAAAGCAGACGCGTACC
GTAGCCGTGGAGACGGTTTTGGCGGATGCCGGCGATGTTCCCGTAAAACGGGTTTCGCAACAGGTGAAGCTGCAAGCAGG
GGAATCGAAGACGGTGCGGCAACGGTTTGCAGTTCGCAATCCTAAGTTATGGTCTCCTGACTCGCCTTATTTGTATAGGA
TACAATCTCGTGTCAAAGCCGGACATGAAGTGTTGGATGGGGGAGTGACACGTGTGGGGATCCGCAAAGCGGAATTTAAA
GGTAAGGATGGCTTTTGGTTGAATGGCAAGCCTTTTGGTCAATTGGTCGGCGCGAACCGTCATCAGGATTTTGCATACGT
GGGTAATGCGCTGCCCAACAGCCAGCAATGGAGGGATGCCAAACGCTTGCGTGATGCAGGATGTACCATTATCCGTGTAG
CTCATTATCCGCAAGATCCGGCATTCATGGATGCTTGCGACGAAATGGGGCTGTTTGTTATTGTGGCTACTCCGGGATGG
CAATATTGGAATAAAAATCCGGAGTTCGCAAAGCTGGTACATCGGAATACCCGTGAGATGATACGCCGGGACCGCAATCA
TCCCAGTGTGCTGATGTGGGAGCCTATTTTGAATGAAACGCCTTATCCGCGCGATTTCGCACTGGAGGCGTTACGGATTA
CACGGGAGGAGTTTCCTTATCCCGGACGTCCTGTAGCGGCAGCCGATGTTCATTCGAAAGGAGTGGCGGAAAACTATGAT
GTGGTGTACGGATGGCCGGGAGATGATGAGAAGGCAGACCGTCCGGAACAATGTATTTTTACTCGTGAGTTTGGCGAGAA
TGTGGATGACTGGTATGCACATAATAATAATAACCGTGCCAGCCGTAGCTGGGGGGAACGCCCGTTGCTGGTGCAGGCGT
TGTCATTATCAAAGAGTTATGATGAAATGTACCGCACTACAGGGCAGTTTGTCGGTGGGGCGCAATGGCATCCTTTTGAC
CATCAGCGGGGGTATCATCCCGATCCGTATTTCGGGGGCATTTATGATGCGTTCCGTCAGCCTAAATACGCTTATTATGC
TTTTCGCAGCCAGTCTGCCGCGACATTGAAGCATCCTGTGGCGGAATGTGGGCCTATGGTGTTTATCGCCCATGAGATGT
CTCCTTTCTCGGATGCCGATGTGGTGGTGTTCAGTAATTGTGACTCGGTTCGTCTCTCTGTCTATGACGGTACTGAGAGC
CGGACGCTTCCGGTTGTTCATGCGCAGGGACACATGCCTAATGCCCCGGTGATATTCAAGGATGTATGGGATTTCTGGGA
AGCACGCGAGTATAGTTATAAGCAAAAAAACTGGCAGAAAGTAAATATGGTGGCAGAAGGAATTATAGACGGTAAAGTGG
TTTGCACCTATAAGCGGATGCCGTCACGCCGCAGCACGAAGTTGCGTATGTATGTGGATACGGAAGGAAAGCAATTGGTG
GCAGACGGTTCGGATTTTATCGTAGTGGTGGCCGAAGTGACGGATGATAGCGGTAATGTGCGCCGTCTGGCAAAAGAAAA
TATCGTATTTACTGTAGAAGGTGAAGGACGAATTATAGGGGATGCCTCTATCAATGCCAATCCGCGCACGGTGGAGTTTG
GCTCTGCTCCCGTATTGATCCGTTCTACCCGCAAGCCCGGCAAAATAAAGGTGAAGGCCCATGTGCAGTTTGAAGGAACG
AATGCACCGGTTGCTACGGAAATAGAATTAGAAAGTATTCCGTCAGAACTGCCTTTCTGTTATACGGAGGAGGAGACGGA
TGCCCAATCAGCCGGAGCAGGACTGGCCGGAAGCCCTGTTAGAACAGAAAGAATGGCGGGGAAAGTTGTGCTGACAGAAG
AGGAAAGGCAAAAAGTATTGATGGAGGTGGAGAGACAGCAAACTGAATTCGGTACGGAGAAGTAA

Upstream 100 bases:

>100_bases
AATGTCTGGATCTTTTTCAAAAACAACAAGACCTTTTTTCAAAAGGAACGGGTACAAACGGACGGCCGGTCCGTCTCTTT
TCCCAGATAGTGTAATAATT

Downstream 100 bases:

>100_bases
TATAGATAGAACGCGGACTTATCTCGTTCCAATCTAACCAATAATTGGTATTTAACTAATTTCAATTTAAGTACCAACGG
ATTTTTTCTTATCTTTGATC

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 874; Mature: 874

Protein sequence:

>874_residues
MKKLFILLVCLLPVLAQAQMETSVAGFIPLSGSGRIVYNFNPGWRFHRGDIKGAEAVRFDDTSWQVVSVPHTVELMPAEA
SGCRNYQGVAWYRKHFVIPQDMKGKEVSLHFEGAMGKQVIYLNGKRVQEHLGGYLPFTVQLTEQGVQPGDSCLLAVMTDN
SDDKNFPPGKRQYTLDFAYHGGIYRDVWMIGKSSVAITDALEADKVAGGGVFVHFDNISGKKAEVYVDTEVHNSGKQTRT
VAVETVLADAGDVPVKRVSQQVKLQAGESKTVRQRFAVRNPKLWSPDSPYLYRIQSRVKAGHEVLDGGVTRVGIRKAEFK
GKDGFWLNGKPFGQLVGANRHQDFAYVGNALPNSQQWRDAKRLRDAGCTIIRVAHYPQDPAFMDACDEMGLFVIVATPGW
QYWNKNPEFAKLVHRNTREMIRRDRNHPSVLMWEPILNETPYPRDFALEALRITREEFPYPGRPVAAADVHSKGVAENYD
VVYGWPGDDEKADRPEQCIFTREFGENVDDWYAHNNNNRASRSWGERPLLVQALSLSKSYDEMYRTTGQFVGGAQWHPFD
HQRGYHPDPYFGGIYDAFRQPKYAYYAFRSQSAATLKHPVAECGPMVFIAHEMSPFSDADVVVFSNCDSVRLSVYDGTES
RTLPVVHAQGHMPNAPVIFKDVWDFWEAREYSYKQKNWQKVNMVAEGIIDGKVVCTYKRMPSRRSTKLRMYVDTEGKQLV
ADGSDFIVVVAEVTDDSGNVRRLAKENIVFTVEGEGRIIGDASINANPRTVEFGSAPVLIRSTRKPGKIKVKAHVQFEGT
NAPVATEIELESIPSELPFCYTEEETDAQSAGAGLAGSPVRTERMAGKVVLTEEERQKVLMEVERQQTEFGTEK

Sequences:

>Translated_874_residues
MKKLFILLVCLLPVLAQAQMETSVAGFIPLSGSGRIVYNFNPGWRFHRGDIKGAEAVRFDDTSWQVVSVPHTVELMPAEA
SGCRNYQGVAWYRKHFVIPQDMKGKEVSLHFEGAMGKQVIYLNGKRVQEHLGGYLPFTVQLTEQGVQPGDSCLLAVMTDN
SDDKNFPPGKRQYTLDFAYHGGIYRDVWMIGKSSVAITDALEADKVAGGGVFVHFDNISGKKAEVYVDTEVHNSGKQTRT
VAVETVLADAGDVPVKRVSQQVKLQAGESKTVRQRFAVRNPKLWSPDSPYLYRIQSRVKAGHEVLDGGVTRVGIRKAEFK
GKDGFWLNGKPFGQLVGANRHQDFAYVGNALPNSQQWRDAKRLRDAGCTIIRVAHYPQDPAFMDACDEMGLFVIVATPGW
QYWNKNPEFAKLVHRNTREMIRRDRNHPSVLMWEPILNETPYPRDFALEALRITREEFPYPGRPVAAADVHSKGVAENYD
VVYGWPGDDEKADRPEQCIFTREFGENVDDWYAHNNNNRASRSWGERPLLVQALSLSKSYDEMYRTTGQFVGGAQWHPFD
HQRGYHPDPYFGGIYDAFRQPKYAYYAFRSQSAATLKHPVAECGPMVFIAHEMSPFSDADVVVFSNCDSVRLSVYDGTES
RTLPVVHAQGHMPNAPVIFKDVWDFWEAREYSYKQKNWQKVNMVAEGIIDGKVVCTYKRMPSRRSTKLRMYVDTEGKQLV
ADGSDFIVVVAEVTDDSGNVRRLAKENIVFTVEGEGRIIGDASINANPRTVEFGSAPVLIRSTRKPGKIKVKAHVQFEGT
NAPVATEIELESIPSELPFCYTEEETDAQSAGAGLAGSPVRTERMAGKVVLTEEERQKVLMEVERQQTEFGTEK
>Mature_874_residues
MKKLFILLVCLLPVLAQAQMETSVAGFIPLSGSGRIVYNFNPGWRFHRGDIKGAEAVRFDDTSWQVVSVPHTVELMPAEA
SGCRNYQGVAWYRKHFVIPQDMKGKEVSLHFEGAMGKQVIYLNGKRVQEHLGGYLPFTVQLTEQGVQPGDSCLLAVMTDN
SDDKNFPPGKRQYTLDFAYHGGIYRDVWMIGKSSVAITDALEADKVAGGGVFVHFDNISGKKAEVYVDTEVHNSGKQTRT
VAVETVLADAGDVPVKRVSQQVKLQAGESKTVRQRFAVRNPKLWSPDSPYLYRIQSRVKAGHEVLDGGVTRVGIRKAEFK
GKDGFWLNGKPFGQLVGANRHQDFAYVGNALPNSQQWRDAKRLRDAGCTIIRVAHYPQDPAFMDACDEMGLFVIVATPGW
QYWNKNPEFAKLVHRNTREMIRRDRNHPSVLMWEPILNETPYPRDFALEALRITREEFPYPGRPVAAADVHSKGVAENYD
VVYGWPGDDEKADRPEQCIFTREFGENVDDWYAHNNNNRASRSWGERPLLVQALSLSKSYDEMYRTTGQFVGGAQWHPFD
HQRGYHPDPYFGGIYDAFRQPKYAYYAFRSQSAATLKHPVAECGPMVFIAHEMSPFSDADVVVFSNCDSVRLSVYDGTES
RTLPVVHAQGHMPNAPVIFKDVWDFWEAREYSYKQKNWQKVNMVAEGIIDGKVVCTYKRMPSRRSTKLRMYVDTEGKQLV
ADGSDFIVVVAEVTDDSGNVRRLAKENIVFTVEGEGRIIGDASINANPRTVEFGSAPVLIRSTRKPGKIKVKAHVQFEGT
NAPVATEIELESIPSELPFCYTEEETDAQSAGAGLAGSPVRTERMAGKVVLTEEERQKVLMEVERQQTEFGTEK

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=569, Percent_Identity=24.780316344464, Blast_Score=105, Evalue=2e-22,
Organism=Escherichia coli, GI1787903, Length=478, Percent_Identity=28.6610878661088, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI48994920, Length=363, Percent_Identity=26.9972451790634, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1786539, Length=342, Percent_Identity=24.2690058479532, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17510825, Length=377, Percent_Identity=28.1167108753316, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI62471735, Length=483, Percent_Identity=25.879917184265, Blast_Score=126, Evalue=6e-29,
Organism=Drosophila melanogaster, GI19922582, Length=483, Percent_Identity=25.879917184265, Blast_Score=126, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24655438, Length=483, Percent_Identity=25.879917184265, Blast_Score=126, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24651745, Length=497, Percent_Identity=25.3521126760563, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 98241; Mature: 98241

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFILLVCLLPVLAQAQMETSVAGFIPLSGSGRIVYNFNPGWRFHRGDIKGAEAVRFD
CHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEECCCCCEEECCCCCCCCEEEEC
DTSWQVVSVPHTVELMPAEASGCRNYQGVAWYRKHFVIPQDMKGKEVSLHFEGAMGKQVI
CCCEEEEECCCEEEEEECCCCCCCCCCCCEEEHHEECCCCCCCCCEEEEEECCCCCCEEE
YLNGKRVQEHLGGYLPFTVQLTEQGVQPGDSCLLAVMTDNSDDKNFPPGKRQYTLDFAYH
EECCHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEC
GGIYRDVWMIGKSSVAITDALEADKVAGGGVFVHFDNISGKKAEVYVDTEVHNSGKQTRT
CCEEEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCEEE
VAVETVLADAGDVPVKRVSQQVKLQAGESKTVRQRFAVRNPKLWSPDSPYLYRIQSRVKA
EEEEEEECCCCCCCHHHHHHHHEEECCCCHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
GHEVLDGGVTRVGIRKAEFKGKDGFWLNGKPFGQLVGANRHQDFAYVGNALPNSQQWRDA
CHHHHCCCCEEEEEEEHCCCCCCCEEECCCCHHHHCCCCCCCCHHHHCCCCCCCHHHHHH
KRLRDAGCTIIRVAHYPQDPAFMDACDEMGLFVIVATPGWQYWNKNPEFAKLVHRNTREM
HHHHHCCCEEEEEECCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
IRRDRNHPSVLMWEPILNETPYPRDFALEALRITREEFPYPGRPVAAADVHSKGVAENYD
HHHCCCCCCEEEECHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCC
VVYGWPGDDEKADRPEQCIFTREFGENVDDWYAHNNNNRASRSWGERPLLVQALSLSKSY
EEEECCCCCCCCCCHHHEEEEHHHCCCCHHHHEECCCCCCCCCCCCCCCEEEEHHHHHHH
DEMYRTTGQFVGGAQWHPFDHQRGYHPDPYFGGIYDAFRQPKYAYYAFRSQSAATLKHPV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCHHHHCCH
AECGPMVFIAHEMSPFSDADVVVFSNCDSVRLSVYDGTESRTLPVVHAQGHMPNAPVIFK
HHHCCEEEEEECCCCCCCCCEEEEECCCEEEEEEEECCCCCEEEEEEECCCCCCCCEEHH
DVWDFWEAREYSYKQKNWQKVNMVAEGIIDGKVVCTYKRMPSRRSTKLRMYVDTEGKQLV
HHHHHHHHHHCCHHHCCCEEEHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEE
ADGSDFIVVVAEVTDDSGNVRRLAKENIVFTVEGEGRIIGDASINANPRTVEFGSAPVLI
ECCCCEEEEEEEEECCCCCHHHHHHCCEEEEECCCCEEEECCCCCCCCCEEEECCCCEEE
RSTRKPGKIKVKAHVQFEGTNAPVATEIELESIPSELPFCYTEEETDAQSAGAGLAGSPV
EECCCCCEEEEEEEEEECCCCCCEEEEEEHHHCCCCCCEEECCCCCCHHHCCCCCCCCCC
RTERMAGKVVLTEEERQKVLMEVERQQTEFGTEK
CHHHHCCEEEEEHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKLFILLVCLLPVLAQAQMETSVAGFIPLSGSGRIVYNFNPGWRFHRGDIKGAEAVRFD
CHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEECCCCCEEECCCCCCCCEEEEC
DTSWQVVSVPHTVELMPAEASGCRNYQGVAWYRKHFVIPQDMKGKEVSLHFEGAMGKQVI
CCCEEEEECCCEEEEEECCCCCCCCCCCCEEEHHEECCCCCCCCCEEEEEECCCCCCEEE
YLNGKRVQEHLGGYLPFTVQLTEQGVQPGDSCLLAVMTDNSDDKNFPPGKRQYTLDFAYH
EECCHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEC
GGIYRDVWMIGKSSVAITDALEADKVAGGGVFVHFDNISGKKAEVYVDTEVHNSGKQTRT
CCEEEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCEEE
VAVETVLADAGDVPVKRVSQQVKLQAGESKTVRQRFAVRNPKLWSPDSPYLYRIQSRVKA
EEEEEEECCCCCCCHHHHHHHHEEECCCCHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
GHEVLDGGVTRVGIRKAEFKGKDGFWLNGKPFGQLVGANRHQDFAYVGNALPNSQQWRDA
CHHHHCCCCEEEEEEEHCCCCCCCEEECCCCHHHHCCCCCCCCHHHHCCCCCCCHHHHHH
KRLRDAGCTIIRVAHYPQDPAFMDACDEMGLFVIVATPGWQYWNKNPEFAKLVHRNTREM
HHHHHCCCEEEEEECCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
IRRDRNHPSVLMWEPILNETPYPRDFALEALRITREEFPYPGRPVAAADVHSKGVAENYD
HHHCCCCCCEEEECHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCC
VVYGWPGDDEKADRPEQCIFTREFGENVDDWYAHNNNNRASRSWGERPLLVQALSLSKSY
EEEECCCCCCCCCCHHHEEEEHHHCCCCHHHHEECCCCCCCCCCCCCCCEEEEHHHHHHH
DEMYRTTGQFVGGAQWHPFDHQRGYHPDPYFGGIYDAFRQPKYAYYAFRSQSAATLKHPV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCHHHHCCH
AECGPMVFIAHEMSPFSDADVVVFSNCDSVRLSVYDGTESRTLPVVHAQGHMPNAPVIFK
HHHCCEEEEEECCCCCCCCCEEEEECCCEEEEEEEECCCCCEEEEEEECCCCCCCCEEHH
DVWDFWEAREYSYKQKNWQKVNMVAEGIIDGKVVCTYKRMPSRRSTKLRMYVDTEGKQLV
HHHHHHHHHHCCHHHCCCEEEHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEE
ADGSDFIVVVAEVTDDSGNVRRLAKENIVFTVEGEGRIIGDASINANPRTVEFGSAPVLI
ECCCCEEEEEEEEECCCCCHHHHHHCCEEEEECCCCEEEECCCCCCCCCEEEECCCCEEE
RSTRKPGKIKVKAHVQFEGTNAPVATEIELESIPSELPFCYTEEETDAQSAGAGLAGSPV
EECCCCCEEEEEEEEEECCCCCCEEEEEEHHHCCCCCCEEECCCCCCHHHCCCCCCCCCC
RTERMAGKVVLTEEERQKVLMEVERQQTEFGTEK
CHHHHCCEEEEEHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA