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The map label for this gene is panC

Identifier: 150005415

GI number: 150005415

Start: 3664990

End: 3665838

Strand: Direct

Name: panC

Synonym: BVU_2898

Alternate gene names: 150005415

Gene position: 3664990-3665838 (Clockwise)

Preceding gene: 150005412

Following gene: 150005416

Centisome position: 70.98

GC content: 45.23

Gene sequence:

>849_bases
ATGAAGTTAGTTCAAACAATCAAAGAGCTTCAGTCAGAGCTGGATGCCCTGCGCAGTGAGGGAAAGACAATAGGTTTGGT
ACCTACGATGGGTGCACTCCATGCCGGACACGCTTCGTTGGTGAAACGTGCTGTTGCAGAAAATGATGTAGTGGTGGTAA
GTGATTTTGTGAATCCTACCCAGTTTAACGACAAAAATGACTTGGCAAAATATCCGCGTACATTGGATGCCGATTGTGAA
TTGTTGGAAAAAGTAGGGGCGGCTTTTGTTTTTGCTCCGTCTGTAGAAGAGATTTATCCTGAGCCTGATACCCGGCAGTT
CAGCTATGCGCCGTTGGACACAGTGATGGAAGGCCGTTTCCGTCCGGGACATTTCAATGGAGTATGCCAGATAGTGAGCA
AGCTGTTTATGATTGTAAATCCTACCCGTGCTTATTTCGGTGAGAAAGATTTCCAGCAGTTGGCTATTATTCGTGAAATG
GTGAAACAGATAGGGTTCAACGGACTGGAAATTGTAGGTTGTCCTATTGTGCGTGAGGAAGACGGGCTGGCATTGAGCAG
CCGCAATGCACGGCTTTCTGCGGTGGAGAGAGAGTATGCGCTGAATATTTCGCAGACTTTATTTAAGAGTTGTACTTTTG
CAAAATCTCATCCGGTCGCTGAGACTCAGAAGTTTGTAGAAGATGCGATTGCTGCCGCTCCGGGTTTGCGTCTGGAATAT
TTTGAAATAGTAGACGGCACTACGCTTCAGAAAATAACGGATTGGGAAGATACGGATTATGCAGTAGGTTGCATTACGGT
ATTTTGCGGAGAGGTACGTTTGATAGATAATATAAAATATAAGGGATAG

Upstream 100 bases:

>100_bases
CATCATTAATTAAAACTCTTTTTTTCTTCGTTATCTCCCAAATAATGGTTTACTTTGCAGCCGTTTTAAATGAAACTACT
CAAACAAAAGAGATAAAAAG

Downstream 100 bases:

>100_bases
TGATCGTTAACCATTAGAATTATGATGATTGAGGTATTAAAGTCGAAACTGCATTGTGTCCGTGTAACGGAAGCCAATTT
GAATTACATGGGTAGTATTA

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKLVQTIKELQSELDALRSEGKTIGLVPTMGALHAGHASLVKRAVAENDVVVVSDFVNPTQFNDKNDLAKYPRTLDADCE
LLEKVGAAFVFAPSVEEIYPEPDTRQFSYAPLDTVMEGRFRPGHFNGVCQIVSKLFMIVNPTRAYFGEKDFQQLAIIREM
VKQIGFNGLEIVGCPIVREEDGLALSSRNARLSAVEREYALNISQTLFKSCTFAKSHPVAETQKFVEDAIAAAPGLRLEY
FEIVDGTTLQKITDWEDTDYAVGCITVFCGEVRLIDNIKYKG

Sequences:

>Translated_282_residues
MKLVQTIKELQSELDALRSEGKTIGLVPTMGALHAGHASLVKRAVAENDVVVVSDFVNPTQFNDKNDLAKYPRTLDADCE
LLEKVGAAFVFAPSVEEIYPEPDTRQFSYAPLDTVMEGRFRPGHFNGVCQIVSKLFMIVNPTRAYFGEKDFQQLAIIREM
VKQIGFNGLEIVGCPIVREEDGLALSSRNARLSAVEREYALNISQTLFKSCTFAKSHPVAETQKFVEDAIAAAPGLRLEY
FEIVDGTTLQKITDWEDTDYAVGCITVFCGEVRLIDNIKYKG
>Mature_282_residues
MKLVQTIKELQSELDALRSEGKTIGLVPTMGALHAGHASLVKRAVAENDVVVVSDFVNPTQFNDKNDLAKYPRTLDADCE
LLEKVGAAFVFAPSVEEIYPEPDTRQFSYAPLDTVMEGRFRPGHFNGVCQIVSKLFMIVNPTRAYFGEKDFQQLAIIREM
VKQIGFNGLEIVGCPIVREEDGLALSSRNARLSAVEREYALNISQTLFKSCTFAKSHPVAETQKFVEDAIAAAPGLRLEY
FEIVDGTTLQKITDWEDTDYAVGCITVFCGEVRLIDNIKYKG

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family

Homologues:

Organism=Escherichia coli, GI1786325, Length=285, Percent_Identity=47.3684210526316, Blast_Score=229, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6322046, Length=260, Percent_Identity=41.1538461538462, Blast_Score=163, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANC_BACV8 (A6L4C3)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001300159.1
- ProteinModelPortal:   A6L4C3
- SMR:   A6L4C3
- STRING:   A6L4C3
- GeneID:   5303859
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_2898
- NMPDR:   fig|435590.6.peg.2715
- eggNOG:   COG0414
- HOGENOM:   HBG428839
- OMA:   DEAHDAK
- ProtClustDB:   PRK00380
- GO:   GO:0005737
- HAMAP:   MF_00158
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02569 Pantoate_ligase

EC number: =6.3.2.1

Molecular weight: Translated: 31338; Mature: 31338

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: ACT_SITE 37-37 BINDING 61-61 BINDING 61-61 BINDING 153-153 BINDING 177-177

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVQTIKELQSELDALRSEGKTIGLVPTMGALHAGHASLVKRAVAENDVVVVSDFVNPT
CCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCHHHHHHHHHCCCCEEEEECCCCCC
QFNDKNDLAKYPRTLDADCELLEKVGAAFVFAPSVEEIYPEPDTRQFSYAPLDTVMEGRF
CCCCCHHHHHCCCCCCHHHHHHHHHCCEEEECCCHHHHCCCCCCCCCCCCCHHHHHCCCC
RPGHFNGVCQIVSKLFMIVNPTRAYFGEKDFQQLAIIREMVKQIGFNGLEIVGCPIVREE
CCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEECC
DGLALSSRNARLSAVEREYALNISQTLFKSCTFAKSHPVAETQKFVEDAIAAAPGLRLEY
CCCEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
FEIVDGTTLQKITDWEDTDYAVGCITVFCGEVRLIDNIKYKG
EEECCCCHHHHHCCCCCCCHHHHHHHHHHCCEEEECCCCCCC
>Mature Secondary Structure
MKLVQTIKELQSELDALRSEGKTIGLVPTMGALHAGHASLVKRAVAENDVVVVSDFVNPT
CCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCHHHHHHHHHCCCCEEEEECCCCCC
QFNDKNDLAKYPRTLDADCELLEKVGAAFVFAPSVEEIYPEPDTRQFSYAPLDTVMEGRF
CCCCCHHHHHCCCCCCHHHHHHHHHCCEEEECCCHHHHCCCCCCCCCCCCCHHHHHCCCC
RPGHFNGVCQIVSKLFMIVNPTRAYFGEKDFQQLAIIREMVKQIGFNGLEIVGCPIVREE
CCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEECC
DGLALSSRNARLSAVEREYALNISQTLFKSCTFAKSHPVAETQKFVEDAIAAAPGLRLEY
CCCEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
FEIVDGTTLQKITDWEDTDYAVGCITVFCGEVRLIDNIKYKG
EEECCCCHHHHHCCCCCCCHHHHHHHHHHCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA