Click here to switch to the map view.

The map label for this gene is lytS [H]

Identifier: 150005328

GI number: 150005328

Start: 3577857

End: 3578912

Strand: Direct

Name: lytS [H]

Synonym: BVU_2804

Alternate gene names: 150005328

Gene position: 3577857-3578912 (Clockwise)

Preceding gene: 150005327

Following gene: 150005329

Centisome position: 69.3

GC content: 43.66

Gene sequence:

>1056_bases
ATGAAACAGTTATTTTCACAACGACGTTTTTTGGAAATGAGTATCCATATTGTCAGTTGGTTGCTCGTTTTTGGCTTTCC
GCTTGTATTCATGGACCGTGGAAGCGGCTTCAATCTGGCCCAATTCTTGAGGCATAGTTGTGTTCCTTTGTGCTATTTTA
TTATCTTCTATGTCAATTACTTGTGCCTGGTTCCCCGCTATATGTTCACGGACGAAATGCGTAAGTATATTCTGAGCAAT
GCCGTGCTGATACTTTGTCTGAGTGTGCTTCTTCATGTATTTCTGGAAAGTATAAGCACTCCTCCGCCTCCTGAGTTTGC
ACGTCATATTCCGCCCCGTTGGATATTTTATGCGCGGGATATGGGGATGATGATTTTTGTTGCCGGATTGGGTGCGGCCA
TTCGTACCAGCCTGCGTTGGCGTCAGGCGGAAGAGCGGTTGATAGAAGCGGAGAGACAAAAGACGGAAGCGGAACTGAAA
AACTTGAAGAACCAGTTGAATCCTCATTTTCTGCTCAATACATTAAATAATATCTATGCTTTGATTGCTTTTAATAGTGA
CAAGGCACAAGAGGCAGTACAAGAGCTGAGTAAATTGTTGCGGCATGTGCTTTATGACAATCAGCAGACTTTTGTTCCGC
TTGAAAAAGAATTGGACTTTATCCGTAATTATGTAGCTCTGATGCGTATCCGCCTGCCACAGCAGGTAGAAGTGAGTGTG
AATTTGGAGGCAGACTCTGGAGGTGCGTTGCAAATCGCTCCCCTTATTTTCATATCGCTGATAGAAAATGCCTTCAAGCA
TGGTATCAGCCCCACGGTAGACAGTTTTATCAGTATCTCTATCTTTGGGCATACGGATGGTACGGTGAGATGTGAGATCC
TTAACAGCAATCATCCGAAGTCCGGGCAAGATAAAAGTGGAAGTGGAGTGGGGCTGGAACAGGTAAGCAAGCGGTTGGAA
CTGATTTATCCGGGACATTACGAATGGATAAAAGGGATCAGTGAAAACGGACAGGTATATTCTTCTATATTAACTATACA
GACTAAAAGTTTATGA

Upstream 100 bases:

>100_bases
GTAAATCAATTTTGTTTCACTGATTCCTGCCAGTCTTATTTTATGGAATAAGAATCATGGAAATCTTATTTCTAATCTAA
TCTTTCTTATCTTTGCCTGT

Downstream 100 bases:

>100_bases
TACTGAATTGTGCTATTGTAGATGATGAGCCGCTGGCTTTGGAATTGCTGAGAAGCTATGTGGAAAAAACGTCTTTCCTC
CGGTTGGTAGGGAGGTATTC

Product: putative two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKQLFSQRRFLEMSIHIVSWLLVFGFPLVFMDRGSGFNLAQFLRHSCVPLCYFIIFYVNYLCLVPRYMFTDEMRKYILSN
AVLILCLSVLLHVFLESISTPPPPEFARHIPPRWIFYARDMGMMIFVAGLGAAIRTSLRWRQAEERLIEAERQKTEAELK
NLKNQLNPHFLLNTLNNIYALIAFNSDKAQEAVQELSKLLRHVLYDNQQTFVPLEKELDFIRNYVALMRIRLPQQVEVSV
NLEADSGGALQIAPLIFISLIENAFKHGISPTVDSFISISIFGHTDGTVRCEILNSNHPKSGQDKSGSGVGLEQVSKRLE
LIYPGHYEWIKGISENGQVYSSILTIQTKSL

Sequences:

>Translated_351_residues
MKQLFSQRRFLEMSIHIVSWLLVFGFPLVFMDRGSGFNLAQFLRHSCVPLCYFIIFYVNYLCLVPRYMFTDEMRKYILSN
AVLILCLSVLLHVFLESISTPPPPEFARHIPPRWIFYARDMGMMIFVAGLGAAIRTSLRWRQAEERLIEAERQKTEAELK
NLKNQLNPHFLLNTLNNIYALIAFNSDKAQEAVQELSKLLRHVLYDNQQTFVPLEKELDFIRNYVALMRIRLPQQVEVSV
NLEADSGGALQIAPLIFISLIENAFKHGISPTVDSFISISIFGHTDGTVRCEILNSNHPKSGQDKSGSGVGLEQVSKRLE
LIYPGHYEWIKGISENGQVYSSILTIQTKSL
>Mature_351_residues
MKQLFSQRRFLEMSIHIVSWLLVFGFPLVFMDRGSGFNLAQFLRHSCVPLCYFIIFYVNYLCLVPRYMFTDEMRKYILSN
AVLILCLSVLLHVFLESISTPPPPEFARHIPPRWIFYARDMGMMIFVAGLGAAIRTSLRWRQAEERLIEAERQKTEAELK
NLKNQLNPHFLLNTLNNIYALIAFNSDKAQEAVQELSKLLRHVLYDNQQTFVPLEKELDFIRNYVALMRIRLPQQVEVSV
NLEADSGGALQIAPLIFISLIENAFKHGISPTVDSFISISIFGHTDGTVRCEILNSNHPKSGQDKSGSGVGLEQVSKRLE
LIYPGHYEWIKGISENGQVYSSILTIQTKSL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=205, Percent_Identity=29.7560975609756, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788446, Length=180, Percent_Identity=30.5555555555556, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40204; Mature: 40204

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLFSQRRFLEMSIHIVSWLLVFGFPLVFMDRGSGFNLAQFLRHSCVPLCYFIIFYVNY
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
LCLVPRYMFTDEMRKYILSNAVLILCLSVLLHVFLESISTPPPPEFARHIPPRWIFYARD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECC
MGMMIFVAGLGAAIRTSLRWRQAEERLIEAERQKTEAELKNLKNQLNPHFLLNTLNNIYA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEE
LIAFNSDKAQEAVQELSKLLRHVLYDNQQTFVPLEKELDFIRNYVALMRIRLPQQVEVSV
EEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
NLEADSGGALQIAPLIFISLIENAFKHGISPTVDSFISISIFGHTDGTVRCEILNSNHPK
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCEEEEEEEECCCCEEEEEEECCCCCC
SGQDKSGSGVGLEQVSKRLELIYPGHYEWIKGISENGQVYSSILTIQTKSL
CCCCCCCCCCCHHHHHHHHHEECCCHHHHHHCCCCCCHHHHHHHEEEECCC
>Mature Secondary Structure
MKQLFSQRRFLEMSIHIVSWLLVFGFPLVFMDRGSGFNLAQFLRHSCVPLCYFIIFYVNY
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
LCLVPRYMFTDEMRKYILSNAVLILCLSVLLHVFLESISTPPPPEFARHIPPRWIFYARD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECC
MGMMIFVAGLGAAIRTSLRWRQAEERLIEAERQKTEAELKNLKNQLNPHFLLNTLNNIYA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEE
LIAFNSDKAQEAVQELSKLLRHVLYDNQQTFVPLEKELDFIRNYVALMRIRLPQQVEVSV
EEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
NLEADSGGALQIAPLIFISLIENAFKHGISPTVDSFISISIFGHTDGTVRCEILNSNHPK
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCEEEEEEEECCCCEEEEEEECCCCCC
SGQDKSGSGVGLEQVSKRLELIYPGHYEWIKGISENGQVYSSILTIQTKSL
CCCCCCCCCCCHHHHHHHHHEECCCHHHHHHCCCCCCHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]