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The map label for this gene is macB [H]

Identifier: 150005327

GI number: 150005327

Start: 3576443

End: 3577663

Strand: Direct

Name: macB [H]

Synonym: BVU_2803

Alternate gene names: 150005327

Gene position: 3576443-3577663 (Clockwise)

Preceding gene: 150005326

Following gene: 150005328

Centisome position: 69.27

GC content: 47.5

Gene sequence:

>1221_bases
ATGAACGGAACGAATCTATTTAAAATAGCTCTCCGGGCTCTTGCCAACAACAAGCTCCGCGCTTTCCTCACCATGTTGGG
GATCATCATCGGTGTGGCATCAGTCATTGCTATGCTTGCCATCGGTCAGGGCTCGAAAAAGAGCATCCAGCAACAAATCT
CGGAGATGGGGTCAAACATGATTATGATTCATCCGGGAGCAGAGATGCGTGGAGGGGTCCGCCAAGACCCTTCGGCCATG
CAGACACTGAAACTGGAAAATTATGAAAAGTTGAGCGAAGAGTGTACTTATCTCTCCGGCATTAGTCCCAACGTTTCTTC
TTCGGGACAACTTGTTGCGGGGGCCAACAACTACCCGTCTTCGGTGAGTGGTGTAAGTATGGATTATCTTACCATACGTC
AGCTCACCGTGGAACAGGGGGAGATGTTTACCGAGAATGACATCCGTACGGCAGCCAAGGTTTGTGTTATCGGTAAAACC
ATTGTCGATAATCTTTTTCCCGACGGATCGGATCCGATAGGGAAAGTGATTCGTTGTAATCAAATTCCTTTCCGGGTAAT
TGGTGTGCTGAAATCAAAAGGGTATAACTCGATGGGCATGGACCAGGACGATGTGGTACTGGCTCCTTACAGTACGGTGA
TGAAACGATTGCTGGCACAGACTTACCTAAGTGGAATTTTTGCTTCGGCTCTGACAGAAGATATGACCGATGAGGCTGTA
GATGAGATAACGACCATTCTGCGTCGTGAACATAAGCTGAAAGAAACGGATGATGATGACTTTACCATCCGCACCCAGCA
GGAGCTGAGTAGTATGCTCAACACTACAACAGACCTGATGACTACCTTGTTGGCTTGTATTGCCGGTATATCTTTGGTGG
TCGGTGGTATCGGTATCATGAATATCATGTATGTGTCTGTAACAGAGCGTACTCGTGAAATAGGTTTGCGTATGTCGGTC
GGGGCTCGAGGAGTAGATATCCTGAGCCAGTTTTTGATAGAGGCTATCCTGATCAGTATCACGGGGGGGCTGATAGGAGT
GATTATCGGTTGTGGAGCCAGTTTTATGATTAAAACGATAGCACATTGGCCTGTATTTATCCAGCCTTGGAGTGTGTTGC
TTTCATTTCTGGTATGTACCGTCACCGGTGTGTTTTTCGGATGGTATCCGGCGAAGAAAGCTGCAGATTTGGATCCGATA
GACGCTTTGCGTTACGAGTAG

Upstream 100 bases:

>100_bases
TGTAGTGGAAGATACCATCAATCCTCAGATCCTTTCGGCCGCTGCCGCGCTGGCTGCCTTGCCCAAGAATGATGAGGACT
AACCATAAAAAAGAATCATT

Downstream 100 bases:

>100_bases
GGATGAAAAGGTGTGGGGGTGAAGCAGAATTGATTTATGGGAATGCTAGTTGGGTTCCGGTCTTTTCCCGATTATCTGTT
TATAATGTTTTTTGTAAATC

Product: ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNGTNLFKIALRALANNKLRAFLTMLGIIIGVASVIAMLAIGQGSKKSIQQQISEMGSNMIMIHPGAEMRGGVRQDPSAM
QTLKLENYEKLSEECTYLSGISPNVSSSGQLVAGANNYPSSVSGVSMDYLTIRQLTVEQGEMFTENDIRTAAKVCVIGKT
IVDNLFPDGSDPIGKVIRCNQIPFRVIGVLKSKGYNSMGMDQDDVVLAPYSTVMKRLLAQTYLSGIFASALTEDMTDEAV
DEITTILRREHKLKETDDDDFTIRTQQELSSMLNTTTDLMTTLLACIAGISLVVGGIGIMNIMYVSVTERTREIGLRMSV
GARGVDILSQFLIEAILISITGGLIGVIIGCGASFMIKTIAHWPVFIQPWSVLLSFLVCTVTGVFFGWYPAKKAADLDPI
DALRYE

Sequences:

>Translated_406_residues
MNGTNLFKIALRALANNKLRAFLTMLGIIIGVASVIAMLAIGQGSKKSIQQQISEMGSNMIMIHPGAEMRGGVRQDPSAM
QTLKLENYEKLSEECTYLSGISPNVSSSGQLVAGANNYPSSVSGVSMDYLTIRQLTVEQGEMFTENDIRTAAKVCVIGKT
IVDNLFPDGSDPIGKVIRCNQIPFRVIGVLKSKGYNSMGMDQDDVVLAPYSTVMKRLLAQTYLSGIFASALTEDMTDEAV
DEITTILRREHKLKETDDDDFTIRTQQELSSMLNTTTDLMTTLLACIAGISLVVGGIGIMNIMYVSVTERTREIGLRMSV
GARGVDILSQFLIEAILISITGGLIGVIIGCGASFMIKTIAHWPVFIQPWSVLLSFLVCTVTGVFFGWYPAKKAADLDPI
DALRYE
>Mature_406_residues
MNGTNLFKIALRALANNKLRAFLTMLGIIIGVASVIAMLAIGQGSKKSIQQQISEMGSNMIMIHPGAEMRGGVRQDPSAM
QTLKLENYEKLSEECTYLSGISPNVSSSGQLVAGANNYPSSVSGVSMDYLTIRQLTVEQGEMFTENDIRTAAKVCVIGKT
IVDNLFPDGSDPIGKVIRCNQIPFRVIGVLKSKGYNSMGMDQDDVVLAPYSTVMKRLLAQTYLSGIFASALTEDMTDEAV
DEITTILRREHKLKETDDDDFTIRTQQELSSMLNTTTDLMTTLLACIAGISLVVGGIGIMNIMYVSVTERTREIGLRMSV
GARGVDILSQFLIEAILISITGGLIGVIIGCGASFMIKTIAHWPVFIQPWSVLLSFLVCTVTGVFFGWYPAKKAADLDPI
DALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=399, Percent_Identity=38.0952380952381, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44140; Mature: 44140

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTNLFKIALRALANNKLRAFLTMLGIIIGVASVIAMLAIGQGSKKSIQQQISEMGSNM
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCE
IMIHPGAEMRGGVRQDPSAMQTLKLENYEKLSEECTYLSGISPNVSSSGQLVAGANNYPS
EEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCC
SVSGVSMDYLTIRQLTVEQGEMFTENDIRTAAKVCVIGKTIVDNLFPDGSDPIGKVIRCN
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECC
QIPFRVIGVLKSKGYNSMGMDQDDVVLAPYSTVMKRLLAQTYLSGIFASALTEDMTDEAV
CCCHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEITTILRREHKLKETDDDDFTIRTQQELSSMLNTTTDLMTTLLACIAGISLVVGGIGIM
HHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIMYVSVTERTREIGLRMSVGARGVDILSQFLIEAILISITGGLIGVIIGCGASFMIKTI
HHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AHWPVFIQPWSVLLSFLVCTVTGVFFGWYPAKKAADLDPIDALRYE
HHCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MNGTNLFKIALRALANNKLRAFLTMLGIIIGVASVIAMLAIGQGSKKSIQQQISEMGSNM
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCE
IMIHPGAEMRGGVRQDPSAMQTLKLENYEKLSEECTYLSGISPNVSSSGQLVAGANNYPS
EEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCC
SVSGVSMDYLTIRQLTVEQGEMFTENDIRTAAKVCVIGKTIVDNLFPDGSDPIGKVIRCN
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECC
QIPFRVIGVLKSKGYNSMGMDQDDVVLAPYSTVMKRLLAQTYLSGIFASALTEDMTDEAV
CCCHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEITTILRREHKLKETDDDDFTIRTQQELSSMLNTTTDLMTTLLACIAGISLVVGGIGIM
HHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIMYVSVTERTREIGLRMSVGARGVDILSQFLIEAILISITGGLIGVIIGCGASFMIKTI
HHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AHWPVFIQPWSVLLSFLVCTVTGVFFGWYPAKKAADLDPIDALRYE
HHCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA