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The map label for this gene is dcuB [H]

Identifier: 150005315

GI number: 150005315

Start: 3560546

End: 3561844

Strand: Direct

Name: dcuB [H]

Synonym: BVU_2791

Alternate gene names: 150005315

Gene position: 3560546-3561844 (Clockwise)

Preceding gene: 150005313

Following gene: 150005316

Centisome position: 68.96

GC content: 47.27

Gene sequence:

>1299_bases
ATGTTATTACAACTGCTATTTGTACTTGTCGCTATTATTGTAGGTGCCCGTCTGGGAGGTATCGGACTGGGAGTGATGGG
AGGTGTGGGCCTTGCCATATTGACCTTTGTTTTCGGACTTCAACCTACCGCTCCCCCTATTGATGTGATGTTGATGATTG
TCGCCGTTATCTCTGCCGCCTCTTGTATGCAGGCTGCCGGCGGACTGGACTATATGGTGAAATTAGCAGAACGGTTGTTG
CGTCGTAACCCTTCACAAGTGACTATCCTGAGTCCGTTGGTTACTTATCTGTTTACTTTTGTCGCAGGTACGGGGCATGT
GGCCTACTCTGTGCTTCCTGTCATAGCCGAGGTGGCTACGGAAACTAAAATTCGTCCTGAGCGTCCTTTAGGCATTGCCG
TTATCGCCTCGCAACAGGCTATTACTGCCAGCCCTATCTCTGCCGCTACCGTAGCGTTGCTGGGATTGCTGACAGGATTT
GACATCACTCTGTTTGATATTCTGAAGATTACTATTCCCGCTACATTAATCGGTGTGCTGGTGGGAGCTTTCCTTTCAAA
GAAGGTGGGTAAAGAGTTGTTGGAAGATCCCGAATACTTGCGCCGCTTGGAAGCCGGGATGATTGATACAAAACATGTGG
AGCTGAACGATGTGAAGAATATGTTTCATGCCCGTATCTCGGTGATAATTTTTATTGCCGCCACGCTGTTGATAGTGTTG
TTCGGTTCTATTCCTGTCATGCGTCCTGTGTTCAATGGTACGGCTTTGGATATGCCGGCTATTATTGAGATTTTGATGTT
GTGTGCGGCGGCTGTTATTCTTCTCATTTCACGTACGGATGGAATTAAAGCTACACAAGGCAGTGTGTTTCCTGCCGGGA
TGCAGGCGGTAATCGCTATATTTGGTATTGCATGGATGGGAGATACCTTCATTAATGGAAACATTACGGAACTGACAGGC
TCTATTGAGGGGATTGTGCGCCAAATGCCCTGGTTGTTCGGTCTGGCATTGTTTGTCATGTCCATTTTGCTTTATAGCCA
GGCTGCTACGGTGCGTGCCATTGTGCCGTTAGGGATAGCACTGGGTATTTCTCCGATGATGTTGATTGCTTTGTTCCCTG
CTGTCAACGGATATTTCTTTATTCCTAATTATCCTACAGTGGTGGCAGCTATAAATTTTGACCGTACAGGAACAACAGGC
ATTGGAAAATGGATTCTGAATCATTCGTTCATGATGCCTGGGATGGTGGCCACCATTGTTTCTATTGTGGTAGGCCTGCT
GCTGGTACAGGTGTTCTAG

Upstream 100 bases:

>100_bases
AAAAAGGAAAAATTCTTAGAAATTTTAAGGTTTGTAGAACAGAAATGGTCTATCTTTGTTCTCAGAATTAAAATTGTATA
TTTATAAACGGATAAAAAAC

Downstream 100 bases:

>100_bases
AAAGGAAAGGGGGTAGGTGTAGTCGGACTTGAAGATGAGTGATCTTCTGCCTGTAACATTTATAATGATTCGATGTATAC
ATATATATCATCGGCACATC

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLLQLLFVLVAIIVGARLGGIGLGVMGGVGLAILTFVFGLQPTAPPIDVMLMIVAVISAASCMQAAGGLDYMVKLAERLL
RRNPSQVTILSPLVTYLFTFVAGTGHVAYSVLPVIAEVATETKIRPERPLGIAVIASQQAITASPISAATVALLGLLTGF
DITLFDILKITIPATLIGVLVGAFLSKKVGKELLEDPEYLRRLEAGMIDTKHVELNDVKNMFHARISVIIFIAATLLIVL
FGSIPVMRPVFNGTALDMPAIIEILMLCAAAVILLISRTDGIKATQGSVFPAGMQAVIAIFGIAWMGDTFINGNITELTG
SIEGIVRQMPWLFGLALFVMSILLYSQAATVRAIVPLGIALGISPMMLIALFPAVNGYFFIPNYPTVVAAINFDRTGTTG
IGKWILNHSFMMPGMVATIVSIVVGLLLVQVF

Sequences:

>Translated_432_residues
MLLQLLFVLVAIIVGARLGGIGLGVMGGVGLAILTFVFGLQPTAPPIDVMLMIVAVISAASCMQAAGGLDYMVKLAERLL
RRNPSQVTILSPLVTYLFTFVAGTGHVAYSVLPVIAEVATETKIRPERPLGIAVIASQQAITASPISAATVALLGLLTGF
DITLFDILKITIPATLIGVLVGAFLSKKVGKELLEDPEYLRRLEAGMIDTKHVELNDVKNMFHARISVIIFIAATLLIVL
FGSIPVMRPVFNGTALDMPAIIEILMLCAAAVILLISRTDGIKATQGSVFPAGMQAVIAIFGIAWMGDTFINGNITELTG
SIEGIVRQMPWLFGLALFVMSILLYSQAATVRAIVPLGIALGISPMMLIALFPAVNGYFFIPNYPTVVAAINFDRTGTTG
IGKWILNHSFMMPGMVATIVSIVVGLLLVQVF
>Mature_432_residues
MLLQLLFVLVAIIVGARLGGIGLGVMGGVGLAILTFVFGLQPTAPPIDVMLMIVAVISAASCMQAAGGLDYMVKLAERLL
RRNPSQVTILSPLVTYLFTFVAGTGHVAYSVLPVIAEVATETKIRPERPLGIAVIASQQAITASPISAATVALLGLLTGF
DITLFDILKITIPATLIGVLVGAFLSKKVGKELLEDPEYLRRLEAGMIDTKHVELNDVKNMFHARISVIIFIAATLLIVL
FGSIPVMRPVFNGTALDMPAIIEILMLCAAAVILLISRTDGIKATQGSVFPAGMQAVIAIFGIAWMGDTFINGNITELTG
SIEGIVRQMPWLFGLALFVMSILLYSQAATVRAIVPLGIALGISPMMLIALFPAVNGYFFIPNYPTVVAAINFDRTGTTG
IGKWILNHSFMMPGMVATIVSIVVGLLLVQVF

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=435, Percent_Identity=42.9885057471264, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1790565, Length=408, Percent_Identity=38.7254901960784, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 45862; Mature: 45862

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLQLLFVLVAIIVGARLGGIGLGVMGGVGLAILTFVFGLQPTAPPIDVMLMIVAVISAA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SCMQAAGGLDYMVKLAERLLRRNPSQVTILSPLVTYLFTFVAGTGHVAYSVLPVIAEVAT
HHHHHHCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ETKIRPERPLGIAVIASQQAITASPISAATVALLGLLTGFDITLFDILKITIPATLIGVL
HCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VGAFLSKKVGKELLEDPEYLRRLEAGMIDTKHVELNDVKNMFHARISVIIFIAATLLIVL
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSIPVMRPVFNGTALDMPAIIEILMLCAAAVILLISRTDGIKATQGSVFPAGMQAVIAI
HCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
FGIAWMGDTFINGNITELTGSIEGIVRQMPWLFGLALFVMSILLYSQAATVRAIVPLGIA
HHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGISPMMLIALFPAVNGYFFIPNYPTVVAAINFDRTGTTGIGKWILNHSFMMPGMVATIV
HHHHHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHH
SIVVGLLLVQVF
HHHHHHHHHHCC
>Mature Secondary Structure
MLLQLLFVLVAIIVGARLGGIGLGVMGGVGLAILTFVFGLQPTAPPIDVMLMIVAVISAA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SCMQAAGGLDYMVKLAERLLRRNPSQVTILSPLVTYLFTFVAGTGHVAYSVLPVIAEVAT
HHHHHHCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ETKIRPERPLGIAVIASQQAITASPISAATVALLGLLTGFDITLFDILKITIPATLIGVL
HCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VGAFLSKKVGKELLEDPEYLRRLEAGMIDTKHVELNDVKNMFHARISVIIFIAATLLIVL
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSIPVMRPVFNGTALDMPAIIEILMLCAAAVILLISRTDGIKATQGSVFPAGMQAVIAI
HCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
FGIAWMGDTFINGNITELTGSIEGIVRQMPWLFGLALFVMSILLYSQAATVRAIVPLGIA
HHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGISPMMLIALFPAVNGYFFIPNYPTVVAAINFDRTGTTGIGKWILNHSFMMPGMVATIV
HHHHHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHH
SIVVGLLLVQVF
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]