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The map label for this gene is sglT [H]

Identifier: 150005313

GI number: 150005313

Start: 3557712

End: 3559145

Strand: Direct

Name: sglT [H]

Synonym: BVU_2789

Alternate gene names: 150005313

Gene position: 3557712-3559145 (Clockwise)

Preceding gene: 150005312

Following gene: 150005315

Centisome position: 68.91

GC content: 46.3

Gene sequence:

>1434_bases
ATGCATATCATTGATATAATCGTCTTTTTGTTGTTTACCGGCGGAGTCGTGGCCTTCGGTTGTTCTTTCTTTAAGAAGAA
AGGTACCTCCGAGGAGTTCACTTCTGCCGGAAGAAGTTTGCCCGGCTGGGTGGTGGGGATGTCCATTTTCGCCACGTATG
TCAGCAGTATCAGTTATCTGGGATATCCGGGAAAGGCCTTTTCGGGAGATTGGAATGCATTTGTATTCAGTCTTTCTATT
CCTATCGCCTCTTATTTTGCGGCTCGTTACTTTGTGCCTTTTTACCGGAGTCAGGACAGCATATCGGCTTATAGCTTTTT
GGAAAACCGTTTCGGTCCTTGGGCACGTATATATGCTTCGTCCTGCTATCTGCTCACCCAGATAGCACGTACAGGGTCTA
TCCTGTATTTGTTGGCGTTGCCCATGAATGTATTGTTGGGATGGCATATCCAGACCATTATTGTTGTAACCAGTGTGGCT
ATTGTGCTTTATTCCATGTTGGGTGGCATGAAGGCTGTCATTTGGACAGAGGCCATACAGGGAATTATTCTGATCGGAGG
TGCGTTGGTATGTATGTTTATTTTGCTTTTTGATATGCCCGGAGGTCCGGTGCAGACTTTCTCCATCGCCATGGAAGATG
GTAAATTCAGCTTGGGAAGCTTTGGAAGCAGTTTAAGTGAGTCCACTTTTTGGGTGTGTCTGATTTATGGTATATTTACT
AATTTGCAGAACTATGGTATAGACCAGAGTTATGTGCAACGTTATCATACGGCGAAGAATGAGAAGGAGGCTAAGTTTTC
GGCCTTGTTCGGAGGATATTTGTTTATTCCCGTTTCGGCCGTTTTCTTTATGATAGGGACTGGACTGTATGCGTTCTATA
AAGTGCATCCGGGGATCTTGCCCGACGGGGTGGGGGCGGATTATGTCTTTCCGTTTTTTATAGTCAATGAGTTGCCGGTG
GGGTTGACAGGCCTGCTGATTGCTTCTATCTTTGCCGCAGGTATGAGTACCATTGCGACCAGTGTCACTAGTTCGTCTAC
CATCATTCTGACGGATTATTATCAGCGGTTCCGCAAACATGCCGGAAACAGGGAGCGGATGTTGGTGCTGAAACTCTCCA
GTGTAGGAGTGGGAGTGGCAGGGATTCTGGTGGCTTTTGCCTTTATGAGTGTGCAAAGTGCGCTGGATGCCTGGTGGGCG
TTGGCGTCTATTTTCAGCGGAGGCATGTTGGGACTGTTTCTATTGGGGTATATTTCGAAGAAAGCACGTAATTTTGATGC
GGTACTGGGAGTCGTTTGTGGAGTAATTCTGGTTTGTTGGATTGTGATATCCCCCTTTGTACATGCCAATCTGGCTATCG
TGTTCGGGACGTTGCTGATATTTTTGGTGGGATTCCTGAGTGCTAATCTGCTTAATAAGAGAAGATGTAAGTAG

Upstream 100 bases:

>100_bases
CCTTTCCATCGCTTCAATGTTCCGGAACGCGAGAAGATACGCAAGGCGTTGGAGGCACTCCCTTTTTGTCCGGAATTGAA
ACCTTAAATGCTCGGTCTGT

Downstream 100 bases:

>100_bases
AATAACTTAATTTTATAAAACTCAACTTTATAGAAAAGAATTTTTCATCTGAAACTTGACATTCTTCATTGACAATAAGA
AGGCCGTATCACTTTTGAGT

Product: sodium-dependent multivitamin transporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MHIIDIIVFLLFTGGVVAFGCSFFKKKGTSEEFTSAGRSLPGWVVGMSIFATYVSSISYLGYPGKAFSGDWNAFVFSLSI
PIASYFAARYFVPFYRSQDSISAYSFLENRFGPWARIYASSCYLLTQIARTGSILYLLALPMNVLLGWHIQTIIVVTSVA
IVLYSMLGGMKAVIWTEAIQGIILIGGALVCMFILLFDMPGGPVQTFSIAMEDGKFSLGSFGSSLSESTFWVCLIYGIFT
NLQNYGIDQSYVQRYHTAKNEKEAKFSALFGGYLFIPVSAVFFMIGTGLYAFYKVHPGILPDGVGADYVFPFFIVNELPV
GLTGLLIASIFAAGMSTIATSVTSSSTIILTDYYQRFRKHAGNRERMLVLKLSSVGVGVAGILVAFAFMSVQSALDAWWA
LASIFSGGMLGLFLLGYISKKARNFDAVLGVVCGVILVCWIVISPFVHANLAIVFGTLLIFLVGFLSANLLNKRRCK

Sequences:

>Translated_477_residues
MHIIDIIVFLLFTGGVVAFGCSFFKKKGTSEEFTSAGRSLPGWVVGMSIFATYVSSISYLGYPGKAFSGDWNAFVFSLSI
PIASYFAARYFVPFYRSQDSISAYSFLENRFGPWARIYASSCYLLTQIARTGSILYLLALPMNVLLGWHIQTIIVVTSVA
IVLYSMLGGMKAVIWTEAIQGIILIGGALVCMFILLFDMPGGPVQTFSIAMEDGKFSLGSFGSSLSESTFWVCLIYGIFT
NLQNYGIDQSYVQRYHTAKNEKEAKFSALFGGYLFIPVSAVFFMIGTGLYAFYKVHPGILPDGVGADYVFPFFIVNELPV
GLTGLLIASIFAAGMSTIATSVTSSSTIILTDYYQRFRKHAGNRERMLVLKLSSVGVGVAGILVAFAFMSVQSALDAWWA
LASIFSGGMLGLFLLGYISKKARNFDAVLGVVCGVILVCWIVISPFVHANLAIVFGTLLIFLVGFLSANLLNKRRCK
>Mature_477_residues
MHIIDIIVFLLFTGGVVAFGCSFFKKKGTSEEFTSAGRSLPGWVVGMSIFATYVSSISYLGYPGKAFSGDWNAFVFSLSI
PIASYFAARYFVPFYRSQDSISAYSFLENRFGPWARIYASSCYLLTQIARTGSILYLLALPMNVLLGWHIQTIIVVTSVA
IVLYSMLGGMKAVIWTEAIQGIILIGGALVCMFILLFDMPGGPVQTFSIAMEDGKFSLGSFGSSLSESTFWVCLIYGIFT
NLQNYGIDQSYVQRYHTAKNEKEAKFSALFGGYLFIPVSAVFFMIGTGLYAFYKVHPGILPDGVGADYVFPFFIVNELPV
GLTGLLIASIFAAGMSTIATSVTSSSTIILTDYYQRFRKHAGNRERMLVLKLSSVGVGVAGILVAFAFMSVQSALDAWWA
LASIFSGGMLGLFLLGYISKKARNFDAVLGVVCGVILVCWIVISPFVHANLAIVFGTLLIFLVGFLSANLLNKRRCK

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI157671931, Length=432, Percent_Identity=29.3981481481481, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI167466278, Length=432, Percent_Identity=27.3148148148148, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI4507035, Length=399, Percent_Identity=27.8195488721804, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI256985183, Length=428, Percent_Identity=27.3364485981308, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI206597483, Length=483, Percent_Identity=28.9855072463768, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI206597487, Length=384, Percent_Identity=29.6875, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI109659836, Length=489, Percent_Identity=26.3803680981595, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI109659839, Length=498, Percent_Identity=26.1044176706827, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4507033, Length=395, Percent_Identity=26.3291139240506, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4507031, Length=415, Percent_Identity=26.0240963855422, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI17941285, Length=408, Percent_Identity=27.6960784313726, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI110835708, Length=371, Percent_Identity=25.8760107816712, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI14140236, Length=421, Percent_Identity=25.41567695962, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1790113, Length=425, Percent_Identity=23.7647058823529, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082237, Length=368, Percent_Identity=23.9130434782609, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790503, Length=414, Percent_Identity=23.6714975845411, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115533094, Length=342, Percent_Identity=25.4385964912281, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32566512, Length=381, Percent_Identity=24.6719160104987, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533096, Length=230, Percent_Identity=25.2173913043478, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221459584, Length=467, Percent_Identity=27.4089935760171, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28573698, Length=434, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24640370, Length=418, Percent_Identity=25.3588516746411, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24651739, Length=453, Percent_Identity=26.0485651214128, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI281362918, Length=457, Percent_Identity=26.9146608315098, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24651741, Length=431, Percent_Identity=25.2900232018561, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24641117, Length=425, Percent_Identity=28, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24645928, Length=443, Percent_Identity=25.5079006772009, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI221459588, Length=438, Percent_Identity=23.972602739726, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI221459586, Length=449, Percent_Identity=22.9398663697105, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI281364280, Length=433, Percent_Identity=25.635103926097, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI19920916, Length=421, Percent_Identity=26.1282660332542, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28574994, Length=459, Percent_Identity=24.6187363834423, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221459582, Length=446, Percent_Identity=25.7847533632287, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI161076631, Length=428, Percent_Identity=25.4672897196262, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI221379702, Length=420, Percent_Identity=26.4285714285714, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281362054, Length=444, Percent_Identity=24.7747747747748, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281362052, Length=444, Percent_Identity=24.7747747747748, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281362050, Length=444, Percent_Identity=24.7747747747748, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24648056, Length=444, Percent_Identity=24.7747747747748, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21356827, Length=444, Percent_Identity=24.7747747747748, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24650192, Length=443, Percent_Identity=22.5733634311512, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 52060; Mature: 52060

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIIDIIVFLLFTGGVVAFGCSFFKKKGTSEEFTSAGRSLPGWVVGMSIFATYVSSISYL
CHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
GYPGKAFSGDWNAFVFSLSIPIASYFAARYFVPFYRSQDSISAYSFLENRFGPWARIYAS
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHH
SCYLLTQIARTGSILYLLALPMNVLLGWHIQTIIVVTSVAIVLYSMLGGMKAVIWTEAIQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GIILIGGALVCMFILLFDMPGGPVQTFSIAMEDGKFSLGSFGSSLSESTFWVCLIYGIFT
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEHHHHCCCCCCHHHHHHHHHHHHH
NLQNYGIDQSYVQRYHTAKNEKEAKFSALFGGYLFIPVSAVFFMIGTGLYAFYKVHPGIL
HHHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PDGVGADYVFPFFIVNELPVGLTGLLIASIFAAGMSTIATSVTSSSTIILTDYYQRFRKH
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
AGNRERMLVLKLSSVGVGVAGILVAFAFMSVQSALDAWWALASIFSGGMLGLFLLGYISK
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KARNFDAVLGVVCGVILVCWIVISPFVHANLAIVFGTLLIFLVGFLSANLLNKRRCK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHIIDIIVFLLFTGGVVAFGCSFFKKKGTSEEFTSAGRSLPGWVVGMSIFATYVSSISYL
CHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
GYPGKAFSGDWNAFVFSLSIPIASYFAARYFVPFYRSQDSISAYSFLENRFGPWARIYAS
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHH
SCYLLTQIARTGSILYLLALPMNVLLGWHIQTIIVVTSVAIVLYSMLGGMKAVIWTEAIQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GIILIGGALVCMFILLFDMPGGPVQTFSIAMEDGKFSLGSFGSSLSESTFWVCLIYGIFT
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEHHHHCCCCCCHHHHHHHHHHHHH
NLQNYGIDQSYVQRYHTAKNEKEAKFSALFGGYLFIPVSAVFFMIGTGLYAFYKVHPGIL
HHHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PDGVGADYVFPFFIVNELPVGLTGLLIASIFAAGMSTIATSVTSSSTIILTDYYQRFRKH
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
AGNRERMLVLKLSSVGVGVAGILVAFAFMSVQSALDAWWALASIFSGGMLGLFLLGYISK
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KARNFDAVLGVVCGVILVCWIVISPFVHANLAIVFGTLLIFLVGFLSANLLNKRRCK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]