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The map label for this gene is mntH [H]

Identifier: 150005270

GI number: 150005270

Start: 3498153

End: 3499406

Strand: Direct

Name: mntH [H]

Synonym: BVU_2742

Alternate gene names: 150005270

Gene position: 3498153-3499406 (Clockwise)

Preceding gene: 150005268

Following gene: 150005273

Centisome position: 67.75

GC content: 47.13

Gene sequence:

>1254_bases
ATGTCTCGCATTATAGATGAATTAAAACGTACGGACCACAAGCGTTATCTGGGTGGTCTTGATTTCTTTAAATATATTGG
TCCCGGATTACTGGTTACTGTAGGTTTTATTGATCCGGGAAACTGGGCCTCGAATTTTGCGGCCGGTTCCGAATTTGGTT
ACGCGTTGTTGTGGGTGGTGACCTTGTCTACCATTATGTTGATTGTGTTGCAGCACAATGTGGCCCACCTGGGCATTGTG
ACGGGATTGTGCCTGAGTGAAGCAGCCACGCAGTATTGTCCCAAGTGGATATCCCGTCCCATTTTGGGCAGCGCGGTGCT
GGCCTCCATATCCACTTCGCTGGCGGAGATACTGGGAGGAGCCATTGCCTTGCAGATGCTTTTGGAAATTCCCATTGCCT
GGGGATCTGTCCTTACTACGATGTTTGTCGTCATTATGCTTTTTTCCAATTCATATAAAAAGATAGAAAGAGCCATCATT
GCTTTTGTATCCGTAATCGGCCTTTCGTTTCTGTATGAGTTGTTTTTGGTGGATATTGACTGGCCTGTGGCGATCCGTTC
CTGGGTGGTTCCTGAGATACCCCAGGGCAGTATGCTGATTATCATGAGCGTACTTGGGGCAGTGGTTATGCCACATAACC
TTTTCTTGCATTCAGAGGTGATACAGAGCCACGAGTACAACAAGCAGGACGAGAGCTCCATTCGTAAAGTATTGAAATAT
GAATTCTATGATACTTTGTTCTCCATGATTGTGGGATGGGCCATCAATAGTGCCATGATCTTACTGGCAGCCGCTACTTT
CTTCCGTACCCGGACTCCGGTGGAAGAGTTGCAGCAGGCGAAGTCGTTGCTTGACCCGTTGCTGGGCAGCCATGCCGGAA
TCATCTTTGCCCTGGCATTGCTGATGGCGGGGATTTCCTCCACCATAACCAGTGGTATGGCGGCAGGTTCTATCTTTGCG
GGTATTTTCGGTGAGTCTTATCATATCAAGGATATCCACTCTAAGGTCGGTATTTTGATTTCTTTGGGGATAGCATTGGT
TCTTATCTTCTTTATTGAGAATCCCTTTTACGGACTTATCATTTCTCAGATGATTCTGAGTATCCAGCTGCCTTTCACGG
TGTTCCTGCAAGTAGGACTGACCTCTTCCAAACGGGTGATGGGCAAATATGCCAACTCCCGGTGGAGTTCATTTGTGCTT
TATACCATTGCGGTGATTGTCTCCGCATTGAATATCATGCTGTTGCTCAGTTGA

Upstream 100 bases:

>100_bases
TAAATCGGTATTTTGAAGCGAAAGTAAACTATAAGTTTGAACAAAGCAAATGGATTTTTGTTTTTTATTAGTAAGTTTGT
GCAAACAAAAAAAGTAAAAC

Downstream 100 bases:

>100_bases
ATAATGTGCGAATTTGCCCATGTGCCAATTGCCATGCGGGACCATAGCGCAGCACGTGGGCACATGGGCAAATTTTTTAT
TTCGTTTTGCTTTCCGAGAT

Product: Mn2+ and Fe2+ transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSRIIDELKRTDHKRYLGGLDFFKYIGPGLLVTVGFIDPGNWASNFAAGSEFGYALLWVVTLSTIMLIVLQHNVAHLGIV
TGLCLSEAATQYCPKWISRPILGSAVLASISTSLAEILGGAIALQMLLEIPIAWGSVLTTMFVVIMLFSNSYKKIERAII
AFVSVIGLSFLYELFLVDIDWPVAIRSWVVPEIPQGSMLIIMSVLGAVVMPHNLFLHSEVIQSHEYNKQDESSIRKVLKY
EFYDTLFSMIVGWAINSAMILLAAATFFRTRTPVEELQQAKSLLDPLLGSHAGIIFALALLMAGISSTITSGMAAGSIFA
GIFGESYHIKDIHSKVGILISLGIALVLIFFIENPFYGLIISQMILSIQLPFTVFLQVGLTSSKRVMGKYANSRWSSFVL
YTIAVIVSALNIMLLLS

Sequences:

>Translated_417_residues
MSRIIDELKRTDHKRYLGGLDFFKYIGPGLLVTVGFIDPGNWASNFAAGSEFGYALLWVVTLSTIMLIVLQHNVAHLGIV
TGLCLSEAATQYCPKWISRPILGSAVLASISTSLAEILGGAIALQMLLEIPIAWGSVLTTMFVVIMLFSNSYKKIERAII
AFVSVIGLSFLYELFLVDIDWPVAIRSWVVPEIPQGSMLIIMSVLGAVVMPHNLFLHSEVIQSHEYNKQDESSIRKVLKY
EFYDTLFSMIVGWAINSAMILLAAATFFRTRTPVEELQQAKSLLDPLLGSHAGIIFALALLMAGISSTITSGMAAGSIFA
GIFGESYHIKDIHSKVGILISLGIALVLIFFIENPFYGLIISQMILSIQLPFTVFLQVGLTSSKRVMGKYANSRWSSFVL
YTIAVIVSALNIMLLLS
>Mature_416_residues
SRIIDELKRTDHKRYLGGLDFFKYIGPGLLVTVGFIDPGNWASNFAAGSEFGYALLWVVTLSTIMLIVLQHNVAHLGIVT
GLCLSEAATQYCPKWISRPILGSAVLASISTSLAEILGGAIALQMLLEIPIAWGSVLTTMFVVIMLFSNSYKKIERAIIA
FVSVIGLSFLYELFLVDIDWPVAIRSWVVPEIPQGSMLIIMSVLGAVVMPHNLFLHSEVIQSHEYNKQDESSIRKVLKYE
FYDTLFSMIVGWAINSAMILLAAATFFRTRTPVEELQQAKSLLDPLLGSHAGIIFALALLMAGISSTITSGMAAGSIFAG
IFGESYHIKDIHSKVGILISLGIALVLIFFIENPFYGLIISQMILSIQLPFTVFLQVGLTSSKRVMGKYANSRWSSFVLY
TIAVIVSALNIMLLLS

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=431, Percent_Identity=28.0742459396752, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI295293178, Length=407, Percent_Identity=29.4840294840295, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI295293171, Length=407, Percent_Identity=29.4840294840295, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI295293169, Length=407, Percent_Identity=29.4840294840295, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI295293175, Length=407, Percent_Identity=29.4840294840295, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI295293173, Length=407, Percent_Identity=29.4840294840295, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI10835169, Length=407, Percent_Identity=29.4840294840295, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI295293167, Length=407, Percent_Identity=29.4840294840295, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1788736, Length=403, Percent_Identity=31.5136476426799, Blast_Score=167, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17569473, Length=381, Percent_Identity=28.8713910761155, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193210616, Length=431, Percent_Identity=27.8422273781903, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71999499, Length=439, Percent_Identity=26.6514806378132, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71993856, Length=224, Percent_Identity=30.3571428571429, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323062, Length=326, Percent_Identity=31.2883435582822, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6324450, Length=421, Percent_Identity=29.6912114014252, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321841, Length=402, Percent_Identity=30.8457711442786, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24648607, Length=444, Percent_Identity=26.1261261261261, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI281362176, Length=444, Percent_Identity=26.1261261261261, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24648609, Length=444, Percent_Identity=26.1261261261261, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI45553443, Length=424, Percent_Identity=26.6509433962264, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 45772; Mature: 45641

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRIIDELKRTDHKRYLGGLDFFKYIGPGLLVTVGFIDPGNWASNFAAGSEFGYALLWVV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCCCHHHHHHHHHH
TLSTIMLIVLQHNVAHLGIVTGLCLSEAATQYCPKWISRPILGSAVLASISTSLAEILGG
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AIALQMLLEIPIAWGSVLTTMFVVIMLFSNSYKKIERAIIAFVSVIGLSFLYELFLVDID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WPVAIRSWVVPEIPQGSMLIIMSVLGAVVMPHNLFLHSEVIQSHEYNKQDESSIRKVLKY
CHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EFYDTLFSMIVGWAINSAMILLAAATFFRTRTPVEELQQAKSLLDPLLGSHAGIIFALAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
LMAGISSTITSGMAAGSIFAGIFGESYHIKDIHSKVGILISLGIALVLIFFIENPFYGLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ISQMILSIQLPFTVFLQVGLTSSKRVMGKYANSRWSSFVLYTIAVIVSALNIMLLLS
HHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]