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The map label for this gene is recQ [H]

Identifier: 150005168

GI number: 150005168

Start: 3345598

End: 3348015

Strand: Direct

Name: recQ [H]

Synonym: BVU_2638

Alternate gene names: 150005168

Gene position: 3345598-3348015 (Clockwise)

Preceding gene: 150005160

Following gene: 150005169

Centisome position: 64.8

GC content: 44.95

Gene sequence:

>2418_bases
ATGATAGAGTCACAGATTGTGGCAAGAGTATTGCCGTCTAAATGCCGTGAAGCGGTAAAGGTCCTTTTGCAGGAAGTGTA
CGGATATGAAGATTTCCGTAATTTAGAAGTTTATGATGACTTGTTCAAAGGTAAGGAAAAATTGCAATTGTCTCAAGGGC
AATTAATTGAGGAGGTCATCATGGAAGCCGAAAAAGGGATCAAGGGTGACTCGTCTGCTCATAATTTGCTCCTGACAGCT
CCGACCGGAGCCGGAAAATCATTGTTGTTTCAGCTCCCTGCCATTTATCTGGGTAATGAATATAAGCTTCTTACTCTTGT
GGTTTCTCCGCTGAAAGCATTGATAGTGGACCAGGTTGAGGCGTTGCAGGAGTTAGGCTATGAACGTGTGGCGTATGCTT
CGTCCGATCTTTCACCTGAACAAAAGAACGAAGTATATCGTCGTGTCCGTGAAGGGGAGGTTGATCTTTTTTATCTTTCC
CCTGAATTATTGTTGGCGTATGATATCAGTTATTTTGTAGGTGAACGCCGCATCGGACTGGTAGTGGTTGACGAGGCTCA
TACCGTGACCACTTGGGGTAAAGAGTTCCGGGTGGATTATTGGTTTCTAGGGCGTCATTTGGAAGCTTTAAAGAATGCGT
TGGGGTATGTATTCCCTGTTTTTGCATTGACGGCCACTGCTGTGTGGAATCCCGAAGGCGGGAACGATATGATTTTTGAT
ACCATCCGGTCGTTGCATCTTGCTCCGTGTGCCTTGTATGTGGGCACGGTGAAGCGTGAAAATATCGGCTTTGACATTAC
CGCCATGACCATAGAGGAGGGGGAAACCTACGATAAGGCCAAGCAACGTACTGTTGCCGCCCGGGTGGAGGATTTTCTGG
ACGGGCATAAGACTATCATTTATTATCCTTTTGCCGGAGGTATAGATATGAAACTGAAGACCTGGGTGTATCCGGCTAAC
TGGCATTGGGTGGCATCTTATTATGGTAAAAAGGATAAAGAGCAAAAAGCCGAAATTATACAAGCTTTTAAGGAGGGTGA
GAAAAAGATAATCGTTGCTACGAAAGCTTTCGGTATGGGGGTGGATATCAGTGATATTGACCGTGTGTATCATGTGGCTC
CATCCAGCACCTTTGTCGATTATATTCAGGAGATTGGCCGTGCTGCCCGTGATAAGAACATTACGGGTGTGGCGGTGACG
GATTTTAATGAGCGCGACTTTTATTATATGAAACGCCTGCATTCTGCGGGTGCCATCTCCCAGGAACAGTTGGGGATGAT
TCTGAAGAAAGTTTGGGAAATATATCTGATGAAAGGCTGTAGTGATGAAATGCAGATGTCTTTATCCGATTTTGAATTTG
CAGTGAAGTTGCCTCGTAAAAAGAACAAGCTGGAATATGAATCGGATTTGGAGCAAGTCGTCAAAACGGCTTTGTTATGG
ATAGAAGAGGATTTGAGTTTCCGGCATGGCGGTTCTCCTGTTGAAATCAATTCACAGACGTTGTTTTCCGATGGCTATGT
GCAGGAAAAGACGGGTGATGCCGCTTTCCGTAAAAAATACAAGCAGTACATGGTTCCCGTGAAAGGGGTTGAAGGAGTCT
ATAAGGTGGCTTTTGAATCTTTGTGGGAGAATTGTTTCTCGGAGATGGGATACCGTGAGTTTAAGCGCGATTTATACAAT
GGAAATCTCTTTGAGGGAGTTCGTGCGGCAGCTGTGGGTAAGCATGATGTCTTGTTAAAAGAGAGTGCGGCGGATATCTG
CTCCAAGCTGGCAAGTCTCTTGAAGAGTTTGAAAGATTTGTTGACGGTGAGTCTGTATGGTAATAAAGGAAAGTTCGAGG
AGGACGATTTGCGTAGTATTTTTGCGGCGTATGATATGGATGTTCCTTCTGCCAAGCGTTTTATCACTTCGTTACTGGAG
TCCAGGGTAGAGGAGGGCAGAAGTGTGAGTTACATCACCAGTGCCAAGAAGAAAGATGAAGACAAACTGATGTTTACCGT
TACCCGTGGTTTTGATTTGTTGCTTTCCCGTTACCAGAAGTTGTGTGCCCAGCGTATCACAGGAAAGAAAGGAGACCGGC
TGTTGTTCTATGTCACTCCGTTCTCCGATCTCAATATGTTGCTCAACTTGTTGTCTATGCTCAATGTGGTGGACTTTACC
GTAGAGGGGGGTGTTCCTTCTGTTGGAGTACGTGTCCGTGATGCAGAGATATTGAAAAAGGAAGCTGCTTCGGGGGACTA
TCAGAACCATGTGCTGGAGAATAATGAGAAAATATTCCAGGAACAGATAGAGTTGTTCCGGCTGTTCTTTGGCAATACAA
AACTGAGCGATGAGCAGCGATGGGAGTTTATAGAGGATTATTTTACGGGGATGAGTTTGGAGGGATTGAAAGAAAAATAT
TCTTGTGTTGTGGAATGA

Upstream 100 bases:

>100_bases
AGAAGGACGAAGAAATCTTCATTCTTCTCGCTTTTTTTATTATATTTGCGCTGATATTAGTTTTAAGGTTGGTACAACCG
TTATTTAAGAGTTCTTTTTT

Downstream 100 bases:

>100_bases
CAGCTGTAAGGGCTGTATAATATAACTCGTTGGCGAAATTAATTTTGCCTTGTATGATTTCACGTTAGTATATGAGGTTG
TGCCAACGTTTTGACACAAC

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 805; Mature: 805

Protein sequence:

>805_residues
MIESQIVARVLPSKCREAVKVLLQEVYGYEDFRNLEVYDDLFKGKEKLQLSQGQLIEEVIMEAEKGIKGDSSAHNLLLTA
PTGAGKSLLFQLPAIYLGNEYKLLTLVVSPLKALIVDQVEALQELGYERVAYASSDLSPEQKNEVYRRVREGEVDLFYLS
PELLLAYDISYFVGERRIGLVVVDEAHTVTTWGKEFRVDYWFLGRHLEALKNALGYVFPVFALTATAVWNPEGGNDMIFD
TIRSLHLAPCALYVGTVKRENIGFDITAMTIEEGETYDKAKQRTVAARVEDFLDGHKTIIYYPFAGGIDMKLKTWVYPAN
WHWVASYYGKKDKEQKAEIIQAFKEGEKKIIVATKAFGMGVDISDIDRVYHVAPSSTFVDYIQEIGRAARDKNITGVAVT
DFNERDFYYMKRLHSAGAISQEQLGMILKKVWEIYLMKGCSDEMQMSLSDFEFAVKLPRKKNKLEYESDLEQVVKTALLW
IEEDLSFRHGGSPVEINSQTLFSDGYVQEKTGDAAFRKKYKQYMVPVKGVEGVYKVAFESLWENCFSEMGYREFKRDLYN
GNLFEGVRAAAVGKHDVLLKESAADICSKLASLLKSLKDLLTVSLYGNKGKFEEDDLRSIFAAYDMDVPSAKRFITSLLE
SRVEEGRSVSYITSAKKKDEDKLMFTVTRGFDLLLSRYQKLCAQRITGKKGDRLLFYVTPFSDLNMLLNLLSMLNVVDFT
VEGGVPSVGVRVRDAEILKKEAASGDYQNHVLENNEKIFQEQIELFRLFFGNTKLSDEQRWEFIEDYFTGMSLEGLKEKY
SCVVE

Sequences:

>Translated_805_residues
MIESQIVARVLPSKCREAVKVLLQEVYGYEDFRNLEVYDDLFKGKEKLQLSQGQLIEEVIMEAEKGIKGDSSAHNLLLTA
PTGAGKSLLFQLPAIYLGNEYKLLTLVVSPLKALIVDQVEALQELGYERVAYASSDLSPEQKNEVYRRVREGEVDLFYLS
PELLLAYDISYFVGERRIGLVVVDEAHTVTTWGKEFRVDYWFLGRHLEALKNALGYVFPVFALTATAVWNPEGGNDMIFD
TIRSLHLAPCALYVGTVKRENIGFDITAMTIEEGETYDKAKQRTVAARVEDFLDGHKTIIYYPFAGGIDMKLKTWVYPAN
WHWVASYYGKKDKEQKAEIIQAFKEGEKKIIVATKAFGMGVDISDIDRVYHVAPSSTFVDYIQEIGRAARDKNITGVAVT
DFNERDFYYMKRLHSAGAISQEQLGMILKKVWEIYLMKGCSDEMQMSLSDFEFAVKLPRKKNKLEYESDLEQVVKTALLW
IEEDLSFRHGGSPVEINSQTLFSDGYVQEKTGDAAFRKKYKQYMVPVKGVEGVYKVAFESLWENCFSEMGYREFKRDLYN
GNLFEGVRAAAVGKHDVLLKESAADICSKLASLLKSLKDLLTVSLYGNKGKFEEDDLRSIFAAYDMDVPSAKRFITSLLE
SRVEEGRSVSYITSAKKKDEDKLMFTVTRGFDLLLSRYQKLCAQRITGKKGDRLLFYVTPFSDLNMLLNLLSMLNVVDFT
VEGGVPSVGVRVRDAEILKKEAASGDYQNHVLENNEKIFQEQIELFRLFFGNTKLSDEQRWEFIEDYFTGMSLEGLKEKY
SCVVE
>Mature_805_residues
MIESQIVARVLPSKCREAVKVLLQEVYGYEDFRNLEVYDDLFKGKEKLQLSQGQLIEEVIMEAEKGIKGDSSAHNLLLTA
PTGAGKSLLFQLPAIYLGNEYKLLTLVVSPLKALIVDQVEALQELGYERVAYASSDLSPEQKNEVYRRVREGEVDLFYLS
PELLLAYDISYFVGERRIGLVVVDEAHTVTTWGKEFRVDYWFLGRHLEALKNALGYVFPVFALTATAVWNPEGGNDMIFD
TIRSLHLAPCALYVGTVKRENIGFDITAMTIEEGETYDKAKQRTVAARVEDFLDGHKTIIYYPFAGGIDMKLKTWVYPAN
WHWVASYYGKKDKEQKAEIIQAFKEGEKKIIVATKAFGMGVDISDIDRVYHVAPSSTFVDYIQEIGRAARDKNITGVAVT
DFNERDFYYMKRLHSAGAISQEQLGMILKKVWEIYLMKGCSDEMQMSLSDFEFAVKLPRKKNKLEYESDLEQVVKTALLW
IEEDLSFRHGGSPVEINSQTLFSDGYVQEKTGDAAFRKKYKQYMVPVKGVEGVYKVAFESLWENCFSEMGYREFKRDLYN
GNLFEGVRAAAVGKHDVLLKESAADICSKLASLLKSLKDLLTVSLYGNKGKFEEDDLRSIFAAYDMDVPSAKRFITSLLE
SRVEEGRSVSYITSAKKKDEDKLMFTVTRGFDLLLSRYQKLCAQRITGKKGDRLLFYVTPFSDLNMLLNLLSMLNVVDFT
VEGGVPSVGVRVRDAEILKKEAASGDYQNHVLENNEKIFQEQIELFRLFFGNTKLSDEQRWEFIEDYFTGMSLEGLKEKY
SCVVE

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI51242947, Length=383, Percent_Identity=28.9817232375979, Blast_Score=128, Evalue=3e-29,
Organism=Homo sapiens, GI51242943, Length=383, Percent_Identity=28.9817232375979, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI284005309, Length=379, Percent_Identity=28.2321899736148, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI148612816, Length=383, Percent_Identity=29.242819843342, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI14591902, Length=497, Percent_Identity=25.1509054325956, Blast_Score=124, Evalue=5e-28,
Organism=Homo sapiens, GI14591904, Length=497, Percent_Identity=25.1509054325956, Blast_Score=124, Evalue=5e-28,
Organism=Homo sapiens, GI110735439, Length=319, Percent_Identity=31.0344827586207, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI169218196, Length=319, Percent_Identity=31.0344827586207, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI4557365, Length=348, Percent_Identity=29.0229885057471, Blast_Score=112, Evalue=1e-24,
Organism=Escherichia coli, GI48994977, Length=398, Percent_Identity=28.894472361809, Blast_Score=140, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI25145561, Length=415, Percent_Identity=27.9518072289157, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17552866, Length=335, Percent_Identity=30.7462686567164, Blast_Score=119, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI32564293, Length=375, Percent_Identity=28.8, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71987997, Length=334, Percent_Identity=29.0419161676647, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71987993, Length=334, Percent_Identity=29.0419161676647, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323844, Length=339, Percent_Identity=30.6784660766962, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21358123, Length=334, Percent_Identity=29.6407185628743, Blast_Score=120, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24646066, Length=348, Percent_Identity=29.3103448275862, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24664226, Length=330, Percent_Identity=30.9090909090909, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI62472181, Length=329, Percent_Identity=31.0030395136778, Blast_Score=109, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24664230, Length=329, Percent_Identity=31.0030395136778, Blast_Score=109, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 91676; Mature: 91676

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIESQIVARVLPSKCREAVKVLLQEVYGYEDFRNLEVYDDLFKGKEKLQLSQGQLIEEVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
MEAEKGIKGDSSAHNLLLTAPTGAGKSLLFQLPAIYLGNEYKLLTLVVSPLKALIVDQVE
HHHHCCCCCCCCCCEEEEECCCCCCHHHHHHCCHHHCCCCEEEHHHHHHHHHHHHHHHHH
ALQELGYERVAYASSDLSPEQKNEVYRRVREGEVDLFYLSPELLLAYDISYFVGERRIGL
HHHHCCCHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCEEEE
VVVDEAHTVTTWGKEFRVDYWFLGRHLEALKNALGYVFPVFALTATAVWNPEGGNDMIFD
EEEECCCEEEECCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHH
TIRSLHLAPCALYVGTVKRENIGFDITAMTIEEGETYDKAKQRTVAARVEDFLDGHKTII
HHHHHHHHHHHHHHHCCEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEE
YYPFAGGIDMKLKTWVYPANWHWVASYYGKKDKEQKAEIIQAFKEGEKKIIVATKAFGMG
EEECCCCCCCEEEEEEECCCCEEHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCC
VDISDIDRVYHVAPSSTFVDYIQEIGRAARDKNITGVAVTDFNERDFYYMKRLHSAGAIS
CCHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCC
QEQLGMILKKVWEIYLMKGCSDEMQMSLSDFEFAVKLPRKKNKLEYESDLEQVVKTALLW
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHH
IEEDLSFRHGGSPVEINSQTLFSDGYVQEKTGDAAFRKKYKQYMVPVKGVEGVYKVAFES
HHHCCCCCCCCCCEEECCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
LWENCFSEMGYREFKRDLYNGNLFEGVRAAAVGKHDVLLKESAADICSKLASLLKSLKDL
HHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTVSLYGNKGKFEEDDLRSIFAAYDMDVPSAKRFITSLLESRVEEGRSVSYITSAKKKDE
HEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCC
DKLMFTVTRGFDLLLSRYQKLCAQRITGKKGDRLLFYVTPFSDLNMLLNLLSMLNVVDFT
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEE
VEGGVPSVGVRVRDAEILKKEAASGDYQNHVLENNEKIFQEQIELFRLFFGNTKLSDEQR
ECCCCCCCCEEECHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHH
WEFIEDYFTGMSLEGLKEKYSCVVE
HHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIESQIVARVLPSKCREAVKVLLQEVYGYEDFRNLEVYDDLFKGKEKLQLSQGQLIEEVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
MEAEKGIKGDSSAHNLLLTAPTGAGKSLLFQLPAIYLGNEYKLLTLVVSPLKALIVDQVE
HHHHCCCCCCCCCCEEEEECCCCCCHHHHHHCCHHHCCCCEEEHHHHHHHHHHHHHHHHH
ALQELGYERVAYASSDLSPEQKNEVYRRVREGEVDLFYLSPELLLAYDISYFVGERRIGL
HHHHCCCHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCEEEE
VVVDEAHTVTTWGKEFRVDYWFLGRHLEALKNALGYVFPVFALTATAVWNPEGGNDMIFD
EEEECCCEEEECCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHH
TIRSLHLAPCALYVGTVKRENIGFDITAMTIEEGETYDKAKQRTVAARVEDFLDGHKTII
HHHHHHHHHHHHHHHCCEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEE
YYPFAGGIDMKLKTWVYPANWHWVASYYGKKDKEQKAEIIQAFKEGEKKIIVATKAFGMG
EEECCCCCCCEEEEEEECCCCEEHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCC
VDISDIDRVYHVAPSSTFVDYIQEIGRAARDKNITGVAVTDFNERDFYYMKRLHSAGAIS
CCHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCC
QEQLGMILKKVWEIYLMKGCSDEMQMSLSDFEFAVKLPRKKNKLEYESDLEQVVKTALLW
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHH
IEEDLSFRHGGSPVEINSQTLFSDGYVQEKTGDAAFRKKYKQYMVPVKGVEGVYKVAFES
HHHCCCCCCCCCCEEECCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
LWENCFSEMGYREFKRDLYNGNLFEGVRAAAVGKHDVLLKESAADICSKLASLLKSLKDL
HHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTVSLYGNKGKFEEDDLRSIFAAYDMDVPSAKRFITSLLESRVEEGRSVSYITSAKKKDE
HEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCC
DKLMFTVTRGFDLLLSRYQKLCAQRITGKKGDRLLFYVTPFSDLNMLLNLLSMLNVVDFT
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEE
VEGGVPSVGVRVRDAEILKKEAASGDYQNHVLENNEKIFQEQIELFRLFFGNTKLSDEQR
ECCCCCCCCEEECHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHH
WEFIEDYFTGMSLEGLKEKYSCVVE
HHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]