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The map label for this gene is pdxA [H]

Identifier: 150005133

GI number: 150005133

Start: 3314379

End: 3315479

Strand: Direct

Name: pdxA [H]

Synonym: BVU_2600

Alternate gene names: 150005133

Gene position: 3314379-3315479 (Clockwise)

Preceding gene: 150005132

Following gene: 150005134

Centisome position: 64.19

GC content: 42.6

Gene sequence:

>1101_bases
ATGGAAGATAACTACAAGATACGAGTTGGTATTACTCATGGGGATATCAACGGAGTAGGATATGAAGTAATTCTCAAAAC
TTTTTCGGATCCTACCATGCTGGAACTTTGTACACCCATTATTTATGGATCGCCTAAAGTGGCTGCTTATCATCGTAAAG
CAATGGATATTCAAACAAATTTCAGTATTGTCAATTCTGCAGATGATGCTCAGCCGGATAAACTGAGCATCGTGAATTGT
ACGGAAGACGAATTGAAGGTGGAGCTCTCCAAACCGACACCGGAGGCTGGTAAAGCAGCTTTGGATGCGTTGGAGAGAGC
TTTGCAGGATTATCGGGAGGGAATGATTGATGTTTTGGTAACTGCTCCTATCAATAAGCATACCATTCAGTCGGAAAGTT
TTCATTTCCCCGGTCATACGGAATATATTGAAGAGCGTGTGGGGGAAGGACAGAAGGCGTTAATGATTTTGCTGAAGAAT
GATTTCCGGGTAGCTTTGGTGACTGGTCATGTTCCTGTACGCGAGATAGCACAAGATATTACCAAGGAACTTATTATGGA
AAAATTGACTGTTTTCCATCGTTCTTTAAAAGAGGATTTTGGCATCGACAGTCCGCGTATAGCTGTGTTTTCATTAAATC
CTCATGCGGGTGATGAGGGATTGATTGGTACGGAAGAGAGTGATATTATAATTCCGGCAATGAAGGAAATGGTTGCCAAA
GGCATTCAGTGTTTCGGACCTTATCCGGCCGATGGCTTTATGGGATCTGGCAACTATACTCATTTTGATGGAATTCTAGC
TATGTATCATGATCAGGGATTGGCTCCTTTCAAAGCTTTGGCAATGGATGAAGGAGTGAATTACACTGCGGGACTTCCCA
TTGTACGTACTTCTCCGGCACATGGTACTGCGTATGATATTGCCGGGCAAGGGGTTGCCTTGGAAGATTCTTTTCGCCAG
GCTATTTATGTGGCTATGGATGTTTTCCGTAACCGTGTTGTCGAGAAAGAGATTCATGCACATCCGCTGCGTAAACAATA
TTATGAAAAACGGGATGATAGCGATAAATTGAAATTGGACACCATTGATGATGAAGATTAA

Upstream 100 bases:

>100_bases
GCTTGATTGACGAAATTGTAATTAGTGGTAATATTCCGGAAGAAAAAATAGATACAACAAGCCGGGTAAAGTAAGAAGAG
ACATATAATATATAATATAG

Downstream 100 bases:

>100_bases
TGGACGATCGGTTTAAAATATAATTTCAAGAAAAAGTAGAAATGAAATTTGCAATTATATCAGCGGGTGAAGGTTCCCGG
CTTTCGCAAGAAGGGGTTGC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MEDNYKIRVGITHGDINGVGYEVILKTFSDPTMLELCTPIIYGSPKVAAYHRKAMDIQTNFSIVNSADDAQPDKLSIVNC
TEDELKVELSKPTPEAGKAALDALERALQDYREGMIDVLVTAPINKHTIQSESFHFPGHTEYIEERVGEGQKALMILLKN
DFRVALVTGHVPVREIAQDITKELIMEKLTVFHRSLKEDFGIDSPRIAVFSLNPHAGDEGLIGTEESDIIIPAMKEMVAK
GIQCFGPYPADGFMGSGNYTHFDGILAMYHDQGLAPFKALAMDEGVNYTAGLPIVRTSPAHGTAYDIAGQGVALEDSFRQ
AIYVAMDVFRNRVVEKEIHAHPLRKQYYEKRDDSDKLKLDTIDDED

Sequences:

>Translated_366_residues
MEDNYKIRVGITHGDINGVGYEVILKTFSDPTMLELCTPIIYGSPKVAAYHRKAMDIQTNFSIVNSADDAQPDKLSIVNC
TEDELKVELSKPTPEAGKAALDALERALQDYREGMIDVLVTAPINKHTIQSESFHFPGHTEYIEERVGEGQKALMILLKN
DFRVALVTGHVPVREIAQDITKELIMEKLTVFHRSLKEDFGIDSPRIAVFSLNPHAGDEGLIGTEESDIIIPAMKEMVAK
GIQCFGPYPADGFMGSGNYTHFDGILAMYHDQGLAPFKALAMDEGVNYTAGLPIVRTSPAHGTAYDIAGQGVALEDSFRQ
AIYVAMDVFRNRVVEKEIHAHPLRKQYYEKRDDSDKLKLDTIDDED
>Mature_366_residues
MEDNYKIRVGITHGDINGVGYEVILKTFSDPTMLELCTPIIYGSPKVAAYHRKAMDIQTNFSIVNSADDAQPDKLSIVNC
TEDELKVELSKPTPEAGKAALDALERALQDYREGMIDVLVTAPINKHTIQSESFHFPGHTEYIEERVGEGQKALMILLKN
DFRVALVTGHVPVREIAQDITKELIMEKLTVFHRSLKEDFGIDSPRIAVFSLNPHAGDEGLIGTEESDIIIPAMKEMVAK
GIQCFGPYPADGFMGSGNYTHFDGILAMYHDQGLAPFKALAMDEGVNYTAGLPIVRTSPAHGTAYDIAGQGVALEDSFRQ
AIYVAMDVFRNRVVEKEIHAHPLRKQYYEKRDDSDKLKLDTIDDED

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=35.5828220858896, Blast_Score=195, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 40676; Mature: 40676

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDNYKIRVGITHGDINGVGYEVILKTFSDPTMLELCTPIIYGSPKVAAYHRKAMDIQTN
CCCCEEEEEEEEECCCCCCCHHHHEECCCCCHHHHHHHHHHCCCCCHHHHHHHHEEEECC
FSIVNSADDAQPDKLSIVNCTEDELKVELSKPTPEAGKAALDALERALQDYREGMIDVLV
CEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEE
TAPINKHTIQSESFHFPGHTEYIEERVGEGQKALMILLKNDFRVALVTGHVPVREIAQDI
ECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCEEEEEEECCCCHHHHHHHH
TKELIMEKLTVFHRSLKEDFGIDSPRIAVFSLNPHAGDEGLIGTEESDIIIPAMKEMVAK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHC
GIQCFGPYPADGFMGSGNYTHFDGILAMYHDQGLAPFKALAMDEGVNYTAGLPIVRTSPA
CHHCCCCCCCCCCCCCCCCCHHHCEEEEEECCCCCHHHHHHHHCCCCEECCCCEEEECCC
HGTAYDIAGQGVALEDSFRQAIYVAMDVFRNRVVEKEIHAHPLRKQYYEKRDDSDKLKLD
CCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEE
TIDDED
CCCCCC
>Mature Secondary Structure
MEDNYKIRVGITHGDINGVGYEVILKTFSDPTMLELCTPIIYGSPKVAAYHRKAMDIQTN
CCCCEEEEEEEEECCCCCCCHHHHEECCCCCHHHHHHHHHHCCCCCHHHHHHHHEEEECC
FSIVNSADDAQPDKLSIVNCTEDELKVELSKPTPEAGKAALDALERALQDYREGMIDVLV
CEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEE
TAPINKHTIQSESFHFPGHTEYIEERVGEGQKALMILLKNDFRVALVTGHVPVREIAQDI
ECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCEEEEEEECCCCHHHHHHHH
TKELIMEKLTVFHRSLKEDFGIDSPRIAVFSLNPHAGDEGLIGTEESDIIIPAMKEMVAK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHC
GIQCFGPYPADGFMGSGNYTHFDGILAMYHDQGLAPFKALAMDEGVNYTAGLPIVRTSPA
CHHCCCCCCCCCCCCCCCCCHHHCEEEEEECCCCCHHHHHHHHCCCCEECCCCEEEECCC
HGTAYDIAGQGVALEDSFRQAIYVAMDVFRNRVVEKEIHAHPLRKQYYEKRDDSDKLKLD
CCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEE
TIDDED
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]