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The map label for this gene is purC [H]

Identifier: 150005078

GI number: 150005078

Start: 3245444

End: 3246388

Strand: Reverse

Name: purC [H]

Synonym: BVU_2543

Alternate gene names: 150005078

Gene position: 3246388-3245444 (Counterclockwise)

Preceding gene: 150005079

Following gene: 150005077

Centisome position: 62.88

GC content: 43.7

Gene sequence:

>945_bases
ATGAGTAAAGCATTAACAAGAACAGACTTTAACTTTCCGGGACAGAAAAGTGTGTACCACGGCAAAGTGCGTGATGTATA
CAACATCAATGACGAAAAGTTAGTAATGGTAGCTACCGACCGTATCTCCGCATTCGACGTAGTTCTGCCTGAAGGTATTC
CCTACAAAGGACAAATGCTGAACCAGATTGCAGCCAAATTTCTGGATGCAACTACCGACATCTGCCCCAACTGGAAAATG
GCGACTCCAGATCCTATGGTTACCGTAGGAGTTATGTGTCAAGGTTTTCCTGTGGAAATGATTGTCCGTGGTTACCTGTG
CGGTAGCGCATGGCGTGCTTACAAAAACGGCGTTCGTGAAATCTGTGGTGTAAAACTTCCCGAAGGAATGAAAGAAAACC
AGAAATTTCCCGAACCAATCATTACTCCAACCACTAAAGCCGAAATGGGCCTGCATGACGAAGACATCTCTAAGGAAGAA
ATTCTGAAACAAGGTCTGGCCACTCCCGAAGAATACGAAATATTGGAAAAGTATACATTGGCTCTGTTCAAACGCGGTAC
TGAAATCGCTGCAGAACGCGGACTGATCCTGGTAGATACCAAATACGAATTCGGTAAACACAACGGCACTATTTATCTGA
TGGATGAGATCCACACTCCGGATTCAAGCCGTTATTTCTACTTGGAAGGTTATGAAGAACGCTTTGCAAAAGGCGAACCT
CAAAAACAACTTTCTAAAGAGTTCGTACGCGAATGGTTGATGGAAAATGGTTTCCAAGGCAAAGAAGGACAACAAGTTCC
CGAAATGACCCCGGAAATCGTTAATTCTATCAGCGAACGCTACATGGAACTGTTCGAACACATCACCGGCGAAAAATTTG
TGAAAGCAGACACTGAAAATATCGCCGCACGTATAGAAAAGAACGTAACCGAATACTTGAAATAA

Upstream 100 bases:

>100_bases
TTGAAGAAAAACAGAAAACCCTTCATTCATGTCATTCTGAACGAAGTGAAAAATCTGAAAACATAAAACGAATTTATTGA
TTTTAATTATAAATAAAGAC

Downstream 100 bases:

>100_bases
ATAAAAATGAAAAATTAAAGATTAAAAGACAGGTACAGGAATCTATCCTCCATCCTCTCCTTTTAATCTTTAATTTTCAA
TTTTAATTAAACATGAACTA

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSKALTRTDFNFPGQKSVYHGKVRDVYNINDEKLVMVATDRISAFDVVLPEGIPYKGQMLNQIAAKFLDATTDICPNWKM
ATPDPMVTVGVMCQGFPVEMIVRGYLCGSAWRAYKNGVREICGVKLPEGMKENQKFPEPIITPTTKAEMGLHDEDISKEE
ILKQGLATPEEYEILEKYTLALFKRGTEIAAERGLILVDTKYEFGKHNGTIYLMDEIHTPDSSRYFYLEGYEERFAKGEP
QKQLSKEFVREWLMENGFQGKEGQQVPEMTPEIVNSISERYMELFEHITGEKFVKADTENIAARIEKNVTEYLK

Sequences:

>Translated_314_residues
MSKALTRTDFNFPGQKSVYHGKVRDVYNINDEKLVMVATDRISAFDVVLPEGIPYKGQMLNQIAAKFLDATTDICPNWKM
ATPDPMVTVGVMCQGFPVEMIVRGYLCGSAWRAYKNGVREICGVKLPEGMKENQKFPEPIITPTTKAEMGLHDEDISKEE
ILKQGLATPEEYEILEKYTLALFKRGTEIAAERGLILVDTKYEFGKHNGTIYLMDEIHTPDSSRYFYLEGYEERFAKGEP
QKQLSKEFVREWLMENGFQGKEGQQVPEMTPEIVNSISERYMELFEHITGEKFVKADTENIAARIEKNVTEYLK
>Mature_313_residues
SKALTRTDFNFPGQKSVYHGKVRDVYNINDEKLVMVATDRISAFDVVLPEGIPYKGQMLNQIAAKFLDATTDICPNWKMA
TPDPMVTVGVMCQGFPVEMIVRGYLCGSAWRAYKNGVREICGVKLPEGMKENQKFPEPIITPTTKAEMGLHDEDISKEEI
LKQGLATPEEYEILEKYTLALFKRGTEIAAERGLILVDTKYEFGKHNGTIYLMDEIHTPDSSRYFYLEGYEERFAKGEPQ
KQLSKEFVREWLMENGFQGKEGQQVPEMTPEIVNSISERYMELFEHITGEKFVKADTENIAARIEKNVTEYLK

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=302, Percent_Identity=37.7483443708609, Blast_Score=183, Evalue=4e-47,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 35901; Mature: 35769

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKALTRTDFNFPGQKSVYHGKVRDVYNINDEKLVMVATDRISAFDVVLPEGIPYKGQML
CCCCCCCCCCCCCCCCCEECCCCCCEECCCCCEEEEEECCCCCEEEEECCCCCCCHHHHH
NQIAAKFLDATTDICPNWKMATPDPMVTVGVMCQGFPVEMIVRGYLCGSAWRAYKNGVRE
HHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ICGVKLPEGMKENQKFPEPIITPTTKAEMGLHDEDISKEEILKQGLATPEEYEILEKYTL
HHCCCCCCCCHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
ALFKRGTEIAAERGLILVDTKYEFGKHNGTIYLMDEIHTPDSSRYFYLEGYEERFAKGEP
HHHHCCHHHHHHCCEEEEECCHHHCCCCCEEEEEEECCCCCCCCEEEEECHHHHHCCCCC
QKQLSKEFVREWLMENGFQGKEGQQVPEMTPEIVNSISERYMELFEHITGEKFVKADTEN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCHHH
IAARIEKNVTEYLK
HHHHHHHHHHHHCC
>Mature Secondary Structure 
SKALTRTDFNFPGQKSVYHGKVRDVYNINDEKLVMVATDRISAFDVVLPEGIPYKGQML
CCCCCCCCCCCCCCCCEECCCCCCEECCCCCEEEEEECCCCCEEEEECCCCCCCHHHHH
NQIAAKFLDATTDICPNWKMATPDPMVTVGVMCQGFPVEMIVRGYLCGSAWRAYKNGVRE
HHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ICGVKLPEGMKENQKFPEPIITPTTKAEMGLHDEDISKEEILKQGLATPEEYEILEKYTL
HHCCCCCCCCHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
ALFKRGTEIAAERGLILVDTKYEFGKHNGTIYLMDEIHTPDSSRYFYLEGYEERFAKGEP
HHHHCCHHHHHHCCEEEEECCHHHCCCCCEEEEEEECCCCCCCCEEEEECHHHHHCCCCC
QKQLSKEFVREWLMENGFQGKEGQQVPEMTPEIVNSISERYMELFEHITGEKFVKADTEN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCHHH
IAARIEKNVTEYLK
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA