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The map label for this gene is trxA [H]

Identifier: 150004905

GI number: 150004905

Start: 3048064

End: 3048522

Strand: Reverse

Name: trxA [H]

Synonym: BVU_2368

Alternate gene names: 150004905

Gene position: 3048522-3048064 (Counterclockwise)

Preceding gene: 150004906

Following gene: 150004902

Centisome position: 59.04

GC content: 39.43

Gene sequence:

>459_bases
ATGAAGAAAACAATCACATGTATTCTATTAACTGCCGGATTAACGGGATATCTCAGTGCCCAAACTCCTGTCCAGGATAA
GTCAGATAAAAATTCAGGAAAAGTCATACGTATGGACAAACAAATGTTCTTGGATAATATATTTGACTACACTTCCGGTT
CCACTAACTGGAAATACAAAGGAGAGAAACCGGCAGTTATTGATTTTTACGCCACATGGTGTGGTCCCTGCCGTATGGTT
GCCCCTCTGCTAAAAAGTCTGGCCAAAGAATACAAAGATCAAATTGCAGTTTACAAAGTAGATACAGACAAACAAAAAGA
ATTATCTGCCGTTATGGGAATACAGTCACTGCCCACCATCATCTTTATTCCCAAAACGGGACAGCCACAAATCATTATAG
GAGCAGCCAATAAAGCTACTTTCAGGAAAGCCATTGAAGAAGTGTTACTGAAAGAATGA

Upstream 100 bases:

>100_bases
CACACTAATGATTTTTAAAAACGGTAAGCAATTGTGGCGACAAAGCGGTGTAATGCGTGCCAATGATTTAAGCACTATTC
TAGCCCAATATGAGTAAAAT

Downstream 100 bases:

>100_bases
GAAACAAGCCCTATATATCTCTAATCTAAATATAACCAATAAAAGAGAGGGGGCAATAATAATTGCTCCCCCTCTCTCCA
TTTATACTATAGCAAATTGT

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKKTITCILLTAGLTGYLSAQTPVQDKSDKNSGKVIRMDKQMFLDNIFDYTSGSTNWKYKGEKPAVIDFYATWCGPCRMV
APLLKSLAKEYKDQIAVYKVDTDKQKELSAVMGIQSLPTIIFIPKTGQPQIIIGAANKATFRKAIEEVLLKE

Sequences:

>Translated_152_residues
MKKTITCILLTAGLTGYLSAQTPVQDKSDKNSGKVIRMDKQMFLDNIFDYTSGSTNWKYKGEKPAVIDFYATWCGPCRMV
APLLKSLAKEYKDQIAVYKVDTDKQKELSAVMGIQSLPTIIFIPKTGQPQIIIGAANKATFRKAIEEVLLKE
>Mature_152_residues
MKKTITCILLTAGLTGYLSAQTPVQDKSDKNSGKVIRMDKQMFLDNIFDYTSGSTNWKYKGEKPAVIDFYATWCGPCRMV
APLLKSLAKEYKDQIAVYKVDTDKQKELSAVMGIQSLPTIIFIPKTGQPQIIIGAANKATFRKAIEEVLLKE

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=134, Percent_Identity=34.3283582089552, Blast_Score=84, Evalue=3e-18,
Organism=Escherichia coli, GI87082331, Length=90, Percent_Identity=30, Blast_Score=66, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71980562, Length=87, Percent_Identity=37.9310344827586, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71980565, Length=87, Percent_Identity=37.9310344827586, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17509965, Length=95, Percent_Identity=31.5789473684211, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=85, Percent_Identity=41.1764705882353, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323072, Length=84, Percent_Identity=35.7142857142857, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639826, Length=73, Percent_Identity=39.7260273972603, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17530795, Length=74, Percent_Identity=40.5405405405405, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17648013, Length=76, Percent_Identity=38.1578947368421, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583090, Length=76, Percent_Identity=38.1578947368421, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24664269, Length=90, Percent_Identity=35.5555555555556, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 16958; Mature: 16958

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTITCILLTAGLTGYLSAQTPVQDKSDKNSGKVIRMDKQMFLDNIFDYTSGSTNWKYK
CCCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEC
GEKPAVIDFYATWCGPCRMVAPLLKSLAKEYKDQIAVYKVDTDKQKELSAVMGIQSLPTI
CCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHCCCCEE
IFIPKTGQPQIIIGAANKATFRKAIEEVLLKE
EEEECCCCCEEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKTITCILLTAGLTGYLSAQTPVQDKSDKNSGKVIRMDKQMFLDNIFDYTSGSTNWKYK
CCCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEC
GEKPAVIDFYATWCGPCRMVAPLLKSLAKEYKDQIAVYKVDTDKQKELSAVMGIQSLPTI
CCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHCCCCEE
IFIPKTGQPQIIIGAANKATFRKAIEEVLLKE
EEEECCCCCEEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]