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The map label for this gene is tkt [H]

Identifier: 150004855

GI number: 150004855

Start: 2991119

End: 2993131

Strand: Reverse

Name: tkt [H]

Synonym: BVU_2318

Alternate gene names: 150004855

Gene position: 2993131-2991119 (Counterclockwise)

Preceding gene: 150004856

Following gene: 150004854

Centisome position: 57.97

GC content: 48.24

Gene sequence:

>2013_bases
ATGAACGAAAAGAAACTTATGAACCGTGCAGCGGACAACATCCGTATTCTGGCTGCTTCGATGGTAGAGAAAGCTAATTC
AGGACACCCGGGTGGAGCTATGGGTGGCGCTGATTTTGTAAACGTGCTTTTCTCTGAGTTTTTAGTTTACGATCCTGAAA
ATCCGCGTTGGGAAGGGCGTGACCGTTTCTTCCTTGATCCAGGCCACATGTCACCGATGCTGTATTCCACTTTGGCACTG
ACCGGCAAGTTCACCATGGAAGAACTGGCACAGTTCCGCCAATGGGGCAGTCCGACTCCGGGACACCCTGAAGTGGACAT
CATGCGCGGTATTGAAAATACTTCCGGCCCGTTAGGACAAGGACACACTTTTGCAGTAGGTGCTGCTATCGCTGCCAAAT
TTCTGAAAGCCCGTCTGGGTCATGTCATGGACCAGACCATCTATGCCTATATATCCGATGGGGGTATTCAAGAAGAGATT
TCTCAGGGTGCAGGCCGTCTGGCAGGTCATTTGGGGCTGGACAACTTGATCATGTTTTATGATTCAAACGACATCCAGCT
GTCTACCGCTACCGATGCTGTTACCAGCGAAGATGTTGCCAAGAAATACGAAGCATGGCACTGGAAAGTAATTACCATCG
ACGGTAATGATCCCGATGCAATCCGCACGGCTCTGACAGAAGCGAAAGCCGTAACCGGTCAGCCCACATTAATTATCGGT
AAGACCATTATGGGTAAAGGCGCACGCAAAGCGGATGATTCCAGTTATGAACGTAACTGTGCCACCCACGGTGCTCCTTT
GGGAGGTGATGCTTACATCAATACAATCAAAAACTTAGGCGGCGATCCAACCGATCCTTTCCAAATCTTCCCTGAAGTAA
AAGAGTTGTATGCCAAACGTGCAGAGGAACTGAAAAAAATTGTTGCAGAAAAATATGCGGCTAAAACTGAATGGACTAAA
GCTAACCCCGAACTGGCTGCTAAATTGGAACTATGGTTCTCTGGCAAAGCTCCGAAAGTAAATTGGAATGTTATCGAACA
AAAAGCCGGAGATGCTACACGCAGCGCTTCTGCCAAAGTTCTCGGTGTACTGGCTACAGAAGTAGAAAACATGATCGTTT
CTTCTGCCGACCTGTCAAATTCAGACAAGACCGACGGTTTCTTGAAGAAAACACATGCATTCACAAAAGACGACTTCACC
GGTGCATTTCTGCAGGCAGGTGTTTCCGAATTAACCATGGCTTGCTGCTGCCTGGGTATGGCACTTCACGGAGGTGTGAT
TGCTGCATGCGCTACCTTCTTCGTATTCTCAGACTACATGAAACCCGCCATACGTATGGCTGCCTTGATGGAACTTCCCG
TCAAATTCATCTGGACACACGACGCATTCCGTGTAGGTGAAGACGGTCCTACTCACGAACCGGTAGAACAAGAAGCACAA
ATCCGCCTGATGGAAAAACTGAAAAACCACAAAGGACACAATTCTATGTTGGTACTCCGTCCGGCAGATGCGGAAGAAAC
CACTGTGGCATGGAAATTGGCCATGGAAAATACCAGCACCCCCACCGCACTGATCTTCTCCCGCCAGAATATCGCGAATC
TGCCTGCAGGAAACGACTATTCACAGGCTGCCAAAGGCGCTTATATTGTTGCAGGCTCCGATGAAAATCCGGATGTAATC
CTAGTCGCTTCAGGTTCCGAAGTTTCCACTTTGGAAGCAGGTGCAGAACTTCTCCGCAAGGATGGCATAAAAATACGTAT
CGTATCCGCTCCTTCTGAGGGATTGTTCCGCAGCCAAAGCAAGGAATACCAAAACAGTATCATTCCCACAGGGGCTAAAG
TATTCGGTCTGACTGCCGGTCTTCCTGTAAACCTTGAAGGTTTGGTAGGTGCCAACGGTAAGGTATTCGGTCTGGAATCA
TTCGGATTCTCCGCTCCTTACAAAGTATTGGATGAAAAGCTGGGCTTTACCGCACAGAACGTGTATAACCAAGTAAAAGA
AATGCTGGCATGA

Upstream 100 bases:

>100_bases
TTGCGGTTTACACATAAAGAGTTATCTTTGCAGATATTAAATAAAATAGCAAAGATAAACCGACTCACTAATAGCATTCA
AATTATAATATTATTTTAAT

Downstream 100 bases:

>100_bases
AAAAAGTAGGACTGGCATCCGATCATGCAGGATTTGAACTGAAAGAGTTTGTAAAGACATGGTTAACTGAAAAAGGCTAT
CCATGCAAAGATTTCGGTAC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MNEKKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGRDRFFLDPGHMSPMLYSTLAL
TGKFTMEELAQFRQWGSPTPGHPEVDIMRGIENTSGPLGQGHTFAVGAAIAAKFLKARLGHVMDQTIYAYISDGGIQEEI
SQGAGRLAGHLGLDNLIMFYDSNDIQLSTATDAVTSEDVAKKYEAWHWKVITIDGNDPDAIRTALTEAKAVTGQPTLIIG
KTIMGKGARKADDSSYERNCATHGAPLGGDAYINTIKNLGGDPTDPFQIFPEVKELYAKRAEELKKIVAEKYAAKTEWTK
ANPELAAKLELWFSGKAPKVNWNVIEQKAGDATRSASAKVLGVLATEVENMIVSSADLSNSDKTDGFLKKTHAFTKDDFT
GAFLQAGVSELTMACCCLGMALHGGVIAACATFFVFSDYMKPAIRMAALMELPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
IRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMENTSTPTALIFSRQNIANLPAGNDYSQAAKGAYIVAGSDENPDVI
LVASGSEVSTLEAGAELLRKDGIKIRIVSAPSEGLFRSQSKEYQNSIIPTGAKVFGLTAGLPVNLEGLVGANGKVFGLES
FGFSAPYKVLDEKLGFTAQNVYNQVKEMLA

Sequences:

>Translated_670_residues
MNEKKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGRDRFFLDPGHMSPMLYSTLAL
TGKFTMEELAQFRQWGSPTPGHPEVDIMRGIENTSGPLGQGHTFAVGAAIAAKFLKARLGHVMDQTIYAYISDGGIQEEI
SQGAGRLAGHLGLDNLIMFYDSNDIQLSTATDAVTSEDVAKKYEAWHWKVITIDGNDPDAIRTALTEAKAVTGQPTLIIG
KTIMGKGARKADDSSYERNCATHGAPLGGDAYINTIKNLGGDPTDPFQIFPEVKELYAKRAEELKKIVAEKYAAKTEWTK
ANPELAAKLELWFSGKAPKVNWNVIEQKAGDATRSASAKVLGVLATEVENMIVSSADLSNSDKTDGFLKKTHAFTKDDFT
GAFLQAGVSELTMACCCLGMALHGGVIAACATFFVFSDYMKPAIRMAALMELPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
IRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMENTSTPTALIFSRQNIANLPAGNDYSQAAKGAYIVAGSDENPDVI
LVASGSEVSTLEAGAELLRKDGIKIRIVSAPSEGLFRSQSKEYQNSIIPTGAKVFGLTAGLPVNLEGLVGANGKVFGLES
FGFSAPYKVLDEKLGFTAQNVYNQVKEMLA
>Mature_670_residues
MNEKKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGRDRFFLDPGHMSPMLYSTLAL
TGKFTMEELAQFRQWGSPTPGHPEVDIMRGIENTSGPLGQGHTFAVGAAIAAKFLKARLGHVMDQTIYAYISDGGIQEEI
SQGAGRLAGHLGLDNLIMFYDSNDIQLSTATDAVTSEDVAKKYEAWHWKVITIDGNDPDAIRTALTEAKAVTGQPTLIIG
KTIMGKGARKADDSSYERNCATHGAPLGGDAYINTIKNLGGDPTDPFQIFPEVKELYAKRAEELKKIVAEKYAAKTEWTK
ANPELAAKLELWFSGKAPKVNWNVIEQKAGDATRSASAKVLGVLATEVENMIVSSADLSNSDKTDGFLKKTHAFTKDDFT
GAFLQAGVSELTMACCCLGMALHGGVIAACATFFVFSDYMKPAIRMAALMELPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
IRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMENTSTPTALIFSRQNIANLPAGNDYSQAAKGAYIVAGSDENPDVI
LVASGSEVSTLEAGAELLRKDGIKIRIVSAPSEGLFRSQSKEYQNSIIPTGAKVFGLTAGLPVNLEGLVGANGKVFGLES
FGFSAPYKVLDEKLGFTAQNVYNQVKEMLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=598, Percent_Identity=27.5919732441472, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI4507521, Length=598, Percent_Identity=27.5919732441472, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI133778974, Length=606, Percent_Identity=24.7524752475248, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI225637459, Length=608, Percent_Identity=23.5197368421053, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI225637463, Length=499, Percent_Identity=24.4488977955912, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI225637461, Length=499, Percent_Identity=24.4488977955912, Blast_Score=90, Evalue=9e-18,
Organism=Escherichia coli, GI1788808, Length=679, Percent_Identity=39.4698085419735, Blast_Score=433, Evalue=1e-122,
Organism=Escherichia coli, GI48994911, Length=678, Percent_Identity=39.5280235988201, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1786304, Length=208, Percent_Identity=29.3269230769231, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17539652, Length=586, Percent_Identity=25.938566552901, Blast_Score=144, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6325331, Length=678, Percent_Identity=36.1356932153392, Blast_Score=356, Evalue=6e-99,
Organism=Saccharomyces cerevisiae, GI6319593, Length=681, Percent_Identity=35.5359765051395, Blast_Score=341, Evalue=2e-94,
Organism=Drosophila melanogaster, GI45551847, Length=676, Percent_Identity=25.5917159763314, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI45550715, Length=676, Percent_Identity=25.5917159763314, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24666278, Length=599, Percent_Identity=25.7095158597663, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24645119, Length=647, Percent_Identity=25.5023183925811, Blast_Score=142, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72464; Mature: 72464

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGR
CCHHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCC
DRFFLDPGHMSPMLYSTLALTGKFTMEELAQFRQWGSPTPGHPEVDIMRGIENTSGPLGQ
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCC
GHTFAVGAAIAAKFLKARLGHVMDQTIYAYISDGGIQEEISQGAGRLAGHLGLDNLIMFY
CCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEE
DSNDIQLSTATDAVTSEDVAKKYEAWHWKVITIDGNDPDAIRTALTEAKAVTGQPTLIIG
ECCCEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEE
KTIMGKGARKADDSSYERNCATHGAPLGGDAYINTIKNLGGDPTDPFQIFPEVKELYAKR
CHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AEELKKIVAEKYAAKTEWTKANPELAAKLELWFSGKAPKVNWNVIEQKAGDATRSASAKV
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCCCCHHCCCHHH
LGVLATEVENMIVSSADLSNSDKTDGFLKKTHAFTKDDFTGAFLQAGVSELTMACCCLGM
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHHH
ALHGGVIAACATFFVFSDYMKPAIRMAALMELPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEECCCCCCCCCCHHHHHH
IRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMENTSTPTALIFSRQNIANLPAGNDY
HHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCH
SQAAKGAYIVAGSDENPDVILVASGSEVSTLEAGAELLRKDGIKIRIVSAPSEGLFRSQS
HHHHCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
KEYQNSIIPTGAKVFGLTAGLPVNLEGLVGANGKVFGLESFGFSAPYKVLDEKLGFTAQN
HHHHHCCCCCCCHHEEEECCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHCCCHHH
VYNQVKEMLA
HHHHHHHHHC
>Mature Secondary Structure
MNEKKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGR
CCHHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCC
DRFFLDPGHMSPMLYSTLALTGKFTMEELAQFRQWGSPTPGHPEVDIMRGIENTSGPLGQ
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCC
GHTFAVGAAIAAKFLKARLGHVMDQTIYAYISDGGIQEEISQGAGRLAGHLGLDNLIMFY
CCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEE
DSNDIQLSTATDAVTSEDVAKKYEAWHWKVITIDGNDPDAIRTALTEAKAVTGQPTLIIG
ECCCEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEE
KTIMGKGARKADDSSYERNCATHGAPLGGDAYINTIKNLGGDPTDPFQIFPEVKELYAKR
CHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AEELKKIVAEKYAAKTEWTKANPELAAKLELWFSGKAPKVNWNVIEQKAGDATRSASAKV
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCCCCHHCCCHHH
LGVLATEVENMIVSSADLSNSDKTDGFLKKTHAFTKDDFTGAFLQAGVSELTMACCCLGM
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHHH
ALHGGVIAACATFFVFSDYMKPAIRMAALMELPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEECCCCCCCCCCHHHHHH
IRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMENTSTPTALIFSRQNIANLPAGNDY
HHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCH
SQAAKGAYIVAGSDENPDVILVASGSEVSTLEAGAELLRKDGIKIRIVSAPSEGLFRSQS
HHHHCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
KEYQNSIIPTGAKVFGLTAGLPVNLEGLVGANGKVFGLESFGFSAPYKVLDEKLGFTAQN
HHHHHCCCCCCCHHEEEECCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHCCCHHH
VYNQVKEMLA
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]