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The map label for this gene is hppA [H]

Identifier: 150004816

GI number: 150004816

Start: 2947333

End: 2949537

Strand: Reverse

Name: hppA [H]

Synonym: BVU_2279

Alternate gene names: 150004816

Gene position: 2949537-2947333 (Counterclockwise)

Preceding gene: 150004817

Following gene: 150004806

Centisome position: 57.13

GC content: 48.75

Gene sequence:

>2205_bases
ATGGAAACGTATCTATTCTGGATTGTGCCCATTGCCTCCCTCTTGGCATTGGTACTTGCATGGTATTTCTACAAACAAAT
GATGCTTGAAAGCGAAGGAACTCCGACGATGGAGAAAATCGCTTCTTATGTGCGCCAGGGCGCCATGTCCTATCTGAAAC
AACAATACAAGGTGGTAGGGCTGGTATTTCTGGGATTAGTTATTCTGTTTTCTATCATGGCATACGGCTTCAACTTACAA
AATCCGTGGGTGCCCATTGCTTTTCTTACCGGCGGTTTCTTCTCCGGACTGTCCGGCTTTTTAGGAATGAAAACGGCTAC
ATACGCTTCTGCACGTACCGCCAATGCCGCCCAACACTCCCTGAACAAAGGACTGCGTGTAGCTTTCCGTAGCGGAGCTG
TTATGGGGTTGGTCGTTGTCGGCTTGGGACTACTCGATATTTCTTTCTGGTACATATTATTGGACTATTGCATTCCCACA
GACGCCTTGAACCCTTCTGCTAAATTATGTGTCATCACAACCACCATGCTTACCTTTGGTATGGGAGCCAGCACACAAGC
ACTTTTCGCCCGTGTAGGAGGTGGAATCTATACCAAGGCAGCCGATGTAGGTGCCGACCTGGTAGGTAAAGTGGAAGCCG
GTATTCCGGAAGATGACCCCCGCAATCCCGCAACCATTGCCGATAATGTGGGAGACAATGTAGGTGACGTAGCCGGAATG
GGCGCCGACCTGTACGAATCCTATTGCGGCTCTATTCTAGCTACCGCCGCTTTAGGTGCTGCCGCTTTTATTGGCTCGGA
TGATACCGTGATGCAGTTTAAAGCGGTTATCGCACCTATGCTGATTGCGGCAGTGGGTATCGTTCTCTCTATCATCGGTA
TTTTTGCCGTCCGTACTAAAGAAAATGCAGGAATGAAGGAATTACTCGGATCATTGGCCACAGGAACCAATTTAAGTTCG
GTACTGATTGTCGTTGCCACTTTCCTTATCCTCTGGGCATTAGGTTTGGAAAATTGGGTAAACATTTCCTTTGCTGTGGT
AGTGGGATTAATAGTAGGTATCGTTATCGGCCGTTCCACCGAATATTATACTTCTCAATCGTATAAACCCACACAACGGT
TGGCCGAAAGTGGAAAGACCGGTCCGGCCACCGTTATCATTTCCGGTATCGGACTAGGTATGGTTTCCACCACCATCCCT
GTACTGGCAGTAGTAACCGGTATCATCTTGTCCTACTGGCTCGCTTCAGGATTTGATTTTGCCAATATTTCCATGGGATT
GTATGGCATCGGTATTGCTGCCGTAGGTATGCTTTCGACATTAGGAATCACCTTGGCTACCGATGCTTACGGACCGATTG
CAGACAATGCCGGCGGTAACGCTGAAATGAGCGGACTGGGCAAAGAAGTACGCAAACGTACTGACGCCCTCGACTCGTTA
GGTAACACGACTGCCGCTACAGGCAAAGGTTTTGCCATCGGCTCCGCAGCTCTGACCGGCCTGGCCCTGCTGGCATCCTA
TGTAGAAGAAATCCGTATCGGATTAACCCGGTTGGGGCAAACCATTCTGGAATTACCAAACGGCATTACCGTAGATGTTC
ATAACGCCAGTTTCACTGACTATATGCTTTATTACGATGTAACCCTGATGAACCCCAAAGTGCTAAGCGGCATGTTTTTG
GGCAGTATGATGGCATTCCTGTTCTGCGGTCTGACCATGAACGCCGTAGGCCGAGCAGCCGCTCACATGGTAGAGGAGGT
GCGTCGCCAGTTCCGTGAAATAAAAGGGATTCTGACAGGAGAGGCAGAACCCGACTATGCCCGTTGCGTACAAATATCCA
CCAAAGGAGCACAACGTGAAATGGTATTCCCCTCTCTACTGGCTATCATTGCCCCTATCGCTACCGGACTGATTTTTGGT
GTTCCCGGTGTTATCGGTCTGCTGATAGGTGGTTTGTCCTCGGGCTTCGTTCTTGCCATTTTTATGGCCAATGCGGGAGG
CGCATGGGATAATGCGAAAAAATTTATAGAAGAAGGTAATTTCGGAGGTAAAGGAAGCGAAGTACACAAAGCAACGGTTA
CCGGTGACACAGTAGGTGATCCGTTTAAAGATACATCCGGACCCAGTTTGAACATTCTGATTAAACTGATGAGTATGGTC
GCCATTGTAATGGCCGGACTGACAGTTGCTTGGAGTTTGTTCTGA

Upstream 100 bases:

>100_bases
CACCGCAAATATTAATTGATAAAAATACGACCTATCCTATTGAATATCATTTATTTTTTGCTATCTTTGGGCAAAACCAA
CTTTTAAATCAATACTGCGT

Downstream 100 bases:

>100_bases
TAGAAAAACGGAAAGCCGCTTCGGAGGAGGCGGCTTTCTAATTTTAAAAAAGATTCTGATAAACTATTTTTAAAACTTCC
CCAACACTTCCATCATTGCC

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 734; Mature: 734

Protein sequence:

>734_residues
METYLFWIVPIASLLALVLAWYFYKQMMLESEGTPTMEKIASYVRQGAMSYLKQQYKVVGLVFLGLVILFSIMAYGFNLQ
NPWVPIAFLTGGFFSGLSGFLGMKTATYASARTANAAQHSLNKGLRVAFRSGAVMGLVVVGLGLLDISFWYILLDYCIPT
DALNPSAKLCVITTTMLTFGMGASTQALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGM
GADLYESYCGSILATAALGAAAFIGSDDTVMQFKAVIAPMLIAAVGIVLSIIGIFAVRTKENAGMKELLGSLATGTNLSS
VLIVVATFLILWALGLENWVNISFAVVVGLIVGIVIGRSTEYYTSQSYKPTQRLAESGKTGPATVIISGIGLGMVSTTIP
VLAVVTGIILSYWLASGFDFANISMGLYGIGIAAVGMLSTLGITLATDAYGPIADNAGGNAEMSGLGKEVRKRTDALDSL
GNTTAATGKGFAIGSAALTGLALLASYVEEIRIGLTRLGQTILELPNGITVDVHNASFTDYMLYYDVTLMNPKVLSGMFL
GSMMAFLFCGLTMNAVGRAAAHMVEEVRRQFREIKGILTGEAEPDYARCVQISTKGAQREMVFPSLLAIIAPIATGLIFG
VPGVIGLLIGGLSSGFVLAIFMANAGGAWDNAKKFIEEGNFGGKGSEVHKATVTGDTVGDPFKDTSGPSLNILIKLMSMV
AIVMAGLTVAWSLF

Sequences:

>Translated_734_residues
METYLFWIVPIASLLALVLAWYFYKQMMLESEGTPTMEKIASYVRQGAMSYLKQQYKVVGLVFLGLVILFSIMAYGFNLQ
NPWVPIAFLTGGFFSGLSGFLGMKTATYASARTANAAQHSLNKGLRVAFRSGAVMGLVVVGLGLLDISFWYILLDYCIPT
DALNPSAKLCVITTTMLTFGMGASTQALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGM
GADLYESYCGSILATAALGAAAFIGSDDTVMQFKAVIAPMLIAAVGIVLSIIGIFAVRTKENAGMKELLGSLATGTNLSS
VLIVVATFLILWALGLENWVNISFAVVVGLIVGIVIGRSTEYYTSQSYKPTQRLAESGKTGPATVIISGIGLGMVSTTIP
VLAVVTGIILSYWLASGFDFANISMGLYGIGIAAVGMLSTLGITLATDAYGPIADNAGGNAEMSGLGKEVRKRTDALDSL
GNTTAATGKGFAIGSAALTGLALLASYVEEIRIGLTRLGQTILELPNGITVDVHNASFTDYMLYYDVTLMNPKVLSGMFL
GSMMAFLFCGLTMNAVGRAAAHMVEEVRRQFREIKGILTGEAEPDYARCVQISTKGAQREMVFPSLLAIIAPIATGLIFG
VPGVIGLLIGGLSSGFVLAIFMANAGGAWDNAKKFIEEGNFGGKGSEVHKATVTGDTVGDPFKDTSGPSLNILIKLMSMV
AIVMAGLTVAWSLF
>Mature_734_residues
METYLFWIVPIASLLALVLAWYFYKQMMLESEGTPTMEKIASYVRQGAMSYLKQQYKVVGLVFLGLVILFSIMAYGFNLQ
NPWVPIAFLTGGFFSGLSGFLGMKTATYASARTANAAQHSLNKGLRVAFRSGAVMGLVVVGLGLLDISFWYILLDYCIPT
DALNPSAKLCVITTTMLTFGMGASTQALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGM
GADLYESYCGSILATAALGAAAFIGSDDTVMQFKAVIAPMLIAAVGIVLSIIGIFAVRTKENAGMKELLGSLATGTNLSS
VLIVVATFLILWALGLENWVNISFAVVVGLIVGIVIGRSTEYYTSQSYKPTQRLAESGKTGPATVIISGIGLGMVSTTIP
VLAVVTGIILSYWLASGFDFANISMGLYGIGIAAVGMLSTLGITLATDAYGPIADNAGGNAEMSGLGKEVRKRTDALDSL
GNTTAATGKGFAIGSAALTGLALLASYVEEIRIGLTRLGQTILELPNGITVDVHNASFTDYMLYYDVTLMNPKVLSGMFL
GSMMAFLFCGLTMNAVGRAAAHMVEEVRRQFREIKGILTGEAEPDYARCVQISTKGAQREMVFPSLLAIIAPIATGLIFG
VPGVIGLLIGGLSSGFVLAIFMANAGGAWDNAKKFIEEGNFGGKGSEVHKATVTGDTVGDPFKDTSGPSLNILIKLMSMV
AIVMAGLTVAWSLF

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 77021; Mature: 77021

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]