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The map label for this gene is dnaX [H]

Identifier: 150004786

GI number: 150004786

Start: 2908442

End: 2910253

Strand: Reverse

Name: dnaX [H]

Synonym: BVU_2249

Alternate gene names: 150004786

Gene position: 2910253-2908442 (Counterclockwise)

Preceding gene: 150004789

Following gene: 150004779

Centisome position: 56.37

GC content: 48.84

Gene sequence:

>1812_bases
ATGGAAAATTATATCGTATCGGCACGAAAATACCGTCCCGCTACATTCGAATCGGTTGTAGGGCAACACGCGTTGACCAT
CACCTTAAAAAATGCTATTGCCACCGGCAAGCTGGCACATGCCTACCTGTTCTGCGGACCGCGTGGAGTGGGAAAAACAA
CGTGTGCACGTATCTTTGCCAAGACCATCAATTGCCAGACCCCCACTGCCGAAGGAGAAGCCTGCAATCAGTGTGAGTCT
TGTCTGGCATTCAACGAACAGCGTTCTTACAACATACATGAGCTGGATGCCGCCAGCAACAACTCGGTAGAAGATATCCG
TTCGCTGATTGAGCAGGTACGTATCCCGCCACAAATCGGCAAGTACAAGGTATATATCATTGATGAGGTCCATATGTTGT
CGCAAGCCGCCTTCAATGCTTTTCTGAAAACATTGGAAGAACCGCCTCATCATGCCATCTTCATCCTTGCCACAACGGAA
AAGCATAAGATACTGCCGACTATTCTGAGCCGTTGCCAGATTTATGACTTCAACCGCATCGGCATCAAAGACACTATCGA
CCATCTGCAATACGTTGCCAAACTGGAACATATCAACGCCGAACCCGAAGCCCTGACTGTCATCGCACAGAAAGCCGACG
GCGGTATGCGCGATGCTCTTTCCATCTTCGACCAGGTAGTCAGCTTCACAGGTGGGAACATCACTTATAAAAGTGTGATT
GAAAACCTGAATGTCTTGGATTACGAATATTATTTCAAGCTGACCGATTTGTTGCTTGAAAACAAAGTTCCCGAATCCAT
GCTGCTTTTTAACGACGTATTGAAAAAAGGATTTGACGGCAGTCATTTCATCACCGGACTATCCTCTCATTTCCGGGATT
TGCTGGTGAGCAAGGACCCTTCCACCCTGCAATTGCTGGAAGTAGGCGCCGGTATCCGCGACCGCTATAAAGAACAAGCA
CAAAAATGCGACCAGAAATTCCTGTACCGTGCCATGAAGCTATGCAATGATTGTGACCTGAACTATCGTGCAAGCAAAAA
CAAACGTCTGCTGGTAGAACTGACACTGATTCAATGCGCCCAACTCACTCTGCCCGATGCCGACGATGCAAGTGGTGGGC
GTGGCCCTAAGAAGATATTAAAACCCCTATTTACGCAGCAAGCGGCTTCCACAGCCGCCACGCAGTCACAGCCTCAGGCT
AAAACTGCCGCTGCACAGACCGCAGCAACCTCCGCTCCTCAGCCACAGGGTACAAGTACAGCCGGCAGTATGAACGCAAG
CCGTCCAAGCCCGCTGCCTCAGACCAGAGAAGAGAAAAAAATCCCGGTGTTCAAGGCGGGCTCACTCGGTATATCCCTGC
GCCGTCCTTTGCACGAACAGCAAGCCGCGGAGAAGCAAGAAGCAAAAGCGGCAAGCACCGCTGCCCAAAACGATGCCACA
TACGAAGATTATATTTTCAATGAAAAAGATCTGGACTATTACTGGCGTGAATTTGCAGCCGCCCTGCCCAAGGAAGAGAA
GGCTAACTCCGCACGAATGATGAACATGCATCCGCATTTGTTGAATGACACGACTTTTGAAGTGACAGTAGACAATGATA
TGGTGGAAAAATATATGGTACAATTGATACCATCGGTTCAGAATCACTTACGCGAACGTCTGCACAACCGGAAAATCACC
ATGACGGTACGTGTCAGTGCCCCTACCGAGAACATCCGTGCTTACAGCCACGTGGAACGTTTCCAGATGATGAGCAAGAA
AAACCCGAATCTGCTGAAATTAAAAGAAGCACTGGGATTGGAGTTATCATAA

Upstream 100 bases:

>100_bases
GATTTTTGCAAAGATAGAAATATTTCAAGCAATCCTACCCATAAAAACGGATAATTTATGTACTTTTGCAGAACTCATAT
TAGAAAAAAGAACTCCGCTT

Downstream 100 bases:

>100_bases
AACCTATTAAAATAAAAAAACACCGGGAAATCCTTCAAATCCTTCATATTTACACAATACATTGTTTTTCAATGTGTTGT
CGTGAAGGATTTTGAAAGGG

Product: putative DNA polymerase III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MENYIVSARKYRPATFESVVGQHALTITLKNAIATGKLAHAYLFCGPRGVGKTTCARIFAKTINCQTPTAEGEACNQCES
CLAFNEQRSYNIHELDAASNNSVEDIRSLIEQVRIPPQIGKYKVYIIDEVHMLSQAAFNAFLKTLEEPPHHAIFILATTE
KHKILPTILSRCQIYDFNRIGIKDTIDHLQYVAKLEHINAEPEALTVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVI
ENLNVLDYEYYFKLTDLLLENKVPESMLLFNDVLKKGFDGSHFITGLSSHFRDLLVSKDPSTLQLLEVGAGIRDRYKEQA
QKCDQKFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQCAQLTLPDADDASGGRGPKKILKPLFTQQAASTAATQSQPQA
KTAAAQTAATSAPQPQGTSTAGSMNASRPSPLPQTREEKKIPVFKAGSLGISLRRPLHEQQAAEKQEAKAASTAAQNDAT
YEDYIFNEKDLDYYWREFAAALPKEEKANSARMMNMHPHLLNDTTFEVTVDNDMVEKYMVQLIPSVQNHLRERLHNRKIT
MTVRVSAPTENIRAYSHVERFQMMSKKNPNLLKLKEALGLELS

Sequences:

>Translated_603_residues
MENYIVSARKYRPATFESVVGQHALTITLKNAIATGKLAHAYLFCGPRGVGKTTCARIFAKTINCQTPTAEGEACNQCES
CLAFNEQRSYNIHELDAASNNSVEDIRSLIEQVRIPPQIGKYKVYIIDEVHMLSQAAFNAFLKTLEEPPHHAIFILATTE
KHKILPTILSRCQIYDFNRIGIKDTIDHLQYVAKLEHINAEPEALTVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVI
ENLNVLDYEYYFKLTDLLLENKVPESMLLFNDVLKKGFDGSHFITGLSSHFRDLLVSKDPSTLQLLEVGAGIRDRYKEQA
QKCDQKFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQCAQLTLPDADDASGGRGPKKILKPLFTQQAASTAATQSQPQA
KTAAAQTAATSAPQPQGTSTAGSMNASRPSPLPQTREEKKIPVFKAGSLGISLRRPLHEQQAAEKQEAKAASTAAQNDAT
YEDYIFNEKDLDYYWREFAAALPKEEKANSARMMNMHPHLLNDTTFEVTVDNDMVEKYMVQLIPSVQNHLRERLHNRKIT
MTVRVSAPTENIRAYSHVERFQMMSKKNPNLLKLKEALGLELS
>Mature_603_residues
MENYIVSARKYRPATFESVVGQHALTITLKNAIATGKLAHAYLFCGPRGVGKTTCARIFAKTINCQTPTAEGEACNQCES
CLAFNEQRSYNIHELDAASNNSVEDIRSLIEQVRIPPQIGKYKVYIIDEVHMLSQAAFNAFLKTLEEPPHHAIFILATTE
KHKILPTILSRCQIYDFNRIGIKDTIDHLQYVAKLEHINAEPEALTVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVI
ENLNVLDYEYYFKLTDLLLENKVPESMLLFNDVLKKGFDGSHFITGLSSHFRDLLVSKDPSTLQLLEVGAGIRDRYKEQA
QKCDQKFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQCAQLTLPDADDASGGRGPKKILKPLFTQQAASTAATQSQPQA
KTAAAQTAATSAPQPQGTSTAGSMNASRPSPLPQTREEKKIPVFKAGSLGISLRRPLHEQQAAEKQEAKAASTAAQNDAT
YEDYIFNEKDLDYYWREFAAALPKEEKANSARMMNMHPHLLNDTTFEVTVDNDMVEKYMVQLIPSVQNHLRERLHNRKIT
MTVRVSAPTENIRAYSHVERFQMMSKKNPNLLKLKEALGLELS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=232, Percent_Identity=25.4310344827586, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI194306571, Length=232, Percent_Identity=25.4310344827586, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI194306567, Length=232, Percent_Identity=25.4310344827586, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI4506491, Length=332, Percent_Identity=24.3975903614458, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI31881687, Length=332, Percent_Identity=24.3975903614458, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=37.3961218836565, Blast_Score=246, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17541988, Length=215, Percent_Identity=25.5813953488372, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324478, Length=309, Percent_Identity=24.2718446601942, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324039, Length=216, Percent_Identity=26.3888888888889, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322528, Length=292, Percent_Identity=23.6301369863014, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17647857, Length=235, Percent_Identity=28.0851063829787, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI18859927, Length=235, Percent_Identity=25.1063829787234, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 67540; Mature: 67540

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYIVSARKYRPATFESVVGQHALTITLKNAIATGKLAHAYLFCGPRGVGKTTCARIFA
CCCCEECHHCCCCCHHHHHHCCCEEEEEEHHHHHHCHHHEEEEEECCCCCCHHHHHHHHH
KTINCQTPTAEGEACNQCESCLAFNEQRSYNIHELDAASNNSVEDIRSLIEQVRIPPQIG
HHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCC
KYKVYIIDEVHMLSQAAFNAFLKTLEEPPHHAIFILATTEKHKILPTILSRCQIYDFNRI
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHEEECCCCC
GIKDTIDHLQYVAKLEHINAEPEALTVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVI
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEHHHHH
ENLNVLDYEYYFKLTDLLLENKVPESMLLFNDVLKKGFDGSHFITGLSSHFRDLLVSKDP
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
STLQLLEVGAGIRDRYKEQAQKCDQKFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQCA
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEHHHH
QLTLPDADDASGGRGPKKILKPLFTQQAASTAATQSQPQAKTAAAQTAATSAPQPQGTST
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
AGSMNASRPSPLPQTREEKKIPVFKAGSLGISLRRPLHEQQAAEKQEAKAASTAAQNDAT
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
YEDYIFNEKDLDYYWREFAAALPKEEKANSARMMNMHPHLLNDTTFEVTVDNDMVEKYMV
HHHHCCCCCCHHHHHHHHHHHCCCHHCCCCCEEEECCCCCCCCCEEEEEECHHHHHHHHH
QLIPSVQNHLRERLHNRKITMTVRVSAPTENIRAYSHVERFQMMSKKNPNLLKLKEALGL
HHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCC
ELS
CCC
>Mature Secondary Structure
MENYIVSARKYRPATFESVVGQHALTITLKNAIATGKLAHAYLFCGPRGVGKTTCARIFA
CCCCEECHHCCCCCHHHHHHCCCEEEEEEHHHHHHCHHHEEEEEECCCCCCHHHHHHHHH
KTINCQTPTAEGEACNQCESCLAFNEQRSYNIHELDAASNNSVEDIRSLIEQVRIPPQIG
HHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCC
KYKVYIIDEVHMLSQAAFNAFLKTLEEPPHHAIFILATTEKHKILPTILSRCQIYDFNRI
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHEEECCCCC
GIKDTIDHLQYVAKLEHINAEPEALTVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVI
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEHHHHH
ENLNVLDYEYYFKLTDLLLENKVPESMLLFNDVLKKGFDGSHFITGLSSHFRDLLVSKDP
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
STLQLLEVGAGIRDRYKEQAQKCDQKFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQCA
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEHHHH
QLTLPDADDASGGRGPKKILKPLFTQQAASTAATQSQPQAKTAAAQTAATSAPQPQGTST
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
AGSMNASRPSPLPQTREEKKIPVFKAGSLGISLRRPLHEQQAAEKQEAKAASTAAQNDAT
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
YEDYIFNEKDLDYYWREFAAALPKEEKANSARMMNMHPHLLNDTTFEVTVDNDMVEKYMV
HHHHCCCCCCHHHHHHHHHHHCCCHHCCCCCEEEECCCCCCCCCEEEEEECHHHHHHHHH
QLIPSVQNHLRERLHNRKITMTVRVSAPTENIRAYSHVERFQMMSKKNPNLLKLKEALGL
HHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCC
ELS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]