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The map label for this gene is murB [H]

Identifier: 150004777

GI number: 150004777

Start: 2899802

End: 2900815

Strand: Direct

Name: murB [H]

Synonym: BVU_2239

Alternate gene names: 150004777

Gene position: 2899802-2900815 (Clockwise)

Preceding gene: 150004776

Following gene: 150004778

Centisome position: 56.16

GC content: 45.96

Gene sequence:

>1014_bases
ATGAAGGAAATAAAAGACTATTCTCTGTTGCCTCATAATACATTTGGTATGGATGTGAAGGCATCTTTGTTTGTGGAATA
TGAATCGGTGACAGAGCTGCAATCCATCTTGTCGGATAAAAACCTGATGGCCGGTAACTGGTTGCATATCGGCGGAGGAA
GCAATTTGCTTTTTAAAGGTGATTATGCAGGGACTGTCCTGCATTCGGCTATCCGGGGGTATGAGGTGGTTGCTGAAAAC
GAACAGGAAATAGAGGTAAGGGCAGGAGCCGGTGAGGTGTGGGATGATTTTGTGGCATATACCGTGAAGAACAGTTGGTA
TGGTGCTGAAAATCTGTCATTGATTCCCGGTGAAGTGGGTGCTTCTGCCGTTCAGAATATCGGTGCGTATGGTGTTGAGG
CAAAAGATTTGATTGTAAGTGTGGAAACCGTCGAGGTGGAAACCGGCAGGAAACGGATTTTTACCAAAGAGGAATGCCGT
TATGCTTATCGTGAAAGCATTTTCAAGAAAGATTTGAAAGGTAAATATATAGTGACTTACGTCACTTATCGTTTAAGTAA
GCAGCCGGTTTTTAATCTGGAGTATGGAAATGTGCGTGGCGAATTGGAAAAGCGAGGAGGTGAGGTGGCATTGGAGAATG
TAAGGAAGGTGATTATTGCCGTGCGTGAAGCCAAGTTGCCCGATCCCCGGGTGCAGGGAAATGCCGGAAGTTTCTTTATG
AATCCGATTGTTCCACGCAGGCAGTTTGAAATAGTACAGCAACAGTATCCTGATATGCCACATTATGAAGTGGATGGCAA
TCGGGTGAAGATTCCTGCTGCATGGATGATAGACCGTTGCGGCTGGAAAGGCAAACAAATAGGGCGCGCGGGTGTTCATT
CTAAACAGGCGTTGGTCTTGGTGAACTGTGGAGGCGCTACGGGAGATGAAGTGATTGCTCTTGCCAGACGGATACAGGAG
TCTGTGCTTCAAAAGTTCGGGGTAGCTATCTCTCCCGAAGTGAATTTTATATAA

Upstream 100 bases:

>100_bases
GTTTTGGCAATGGATTTAATAATACGCTCTATTTTGAACGGCGGCACGGTCTATGGAAACTGATGCAGTTTGAGGATCTG
AGCGATTGATTTGATTGTAA

Downstream 100 bases:

>100_bases
AGTATAATATGAAGATTACAATACTAGGCAGCGGAACGTCTACGGGAGTACCCGAAATAGGGTGCAAATGTCCGGTATGT
ACCAGCAGCGATCCCCGGGA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKEIKDYSLLPHNTFGMDVKASLFVEYESVTELQSILSDKNLMAGNWLHIGGGSNLLFKGDYAGTVLHSAIRGYEVVAEN
EQEIEVRAGAGEVWDDFVAYTVKNSWYGAENLSLIPGEVGASAVQNIGAYGVEAKDLIVSVETVEVETGRKRIFTKEECR
YAYRESIFKKDLKGKYIVTYVTYRLSKQPVFNLEYGNVRGELEKRGGEVALENVRKVIIAVREAKLPDPRVQGNAGSFFM
NPIVPRRQFEIVQQQYPDMPHYEVDGNRVKIPAAWMIDRCGWKGKQIGRAGVHSKQALVLVNCGGATGDEVIALARRIQE
SVLQKFGVAISPEVNFI

Sequences:

>Translated_337_residues
MKEIKDYSLLPHNTFGMDVKASLFVEYESVTELQSILSDKNLMAGNWLHIGGGSNLLFKGDYAGTVLHSAIRGYEVVAEN
EQEIEVRAGAGEVWDDFVAYTVKNSWYGAENLSLIPGEVGASAVQNIGAYGVEAKDLIVSVETVEVETGRKRIFTKEECR
YAYRESIFKKDLKGKYIVTYVTYRLSKQPVFNLEYGNVRGELEKRGGEVALENVRKVIIAVREAKLPDPRVQGNAGSFFM
NPIVPRRQFEIVQQQYPDMPHYEVDGNRVKIPAAWMIDRCGWKGKQIGRAGVHSKQALVLVNCGGATGDEVIALARRIQE
SVLQKFGVAISPEVNFI
>Mature_337_residues
MKEIKDYSLLPHNTFGMDVKASLFVEYESVTELQSILSDKNLMAGNWLHIGGGSNLLFKGDYAGTVLHSAIRGYEVVAEN
EQEIEVRAGAGEVWDDFVAYTVKNSWYGAENLSLIPGEVGASAVQNIGAYGVEAKDLIVSVETVEVETGRKRIFTKEECR
YAYRESIFKKDLKGKYIVTYVTYRLSKQPVFNLEYGNVRGELEKRGGEVALENVRKVIIAVREAKLPDPRVQGNAGSFFM
NPIVPRRQFEIVQQQYPDMPHYEVDGNRVKIPAAWMIDRCGWKGKQIGRAGVHSKQALVLVNCGGATGDEVIALARRIQE
SVLQKFGVAISPEVNFI

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=334, Percent_Identity=41.6167664670659, Blast_Score=242, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37587; Mature: 37587

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIKDYSLLPHNTFGMDVKASLFVEYESVTELQSILSDKNLMAGNWLHIGGGSNLLFKG
CCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEC
DYAGTVLHSAIRGYEVVAENEQEIEVRAGAGEVWDDFVAYTVKNSWYGAENLSLIPGEVG
CCHHHHHHHHHCCEEEEECCCCEEEEECCCCHHHHHHEEEEEECCCCCCCCCEECCCCCC
ASAVQNIGAYGVEAKDLIVSVETVEVETGRKRIFTKEECRYAYRESIFKKDLKGKYIVTY
HHHHHHCCCCCCCHHHEEEEEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEE
VTYRLSKQPVFNLEYGNVRGELEKRGGEVALENVRKVIIAVREAKLPDPRVQGNAGSFFM
EEEEECCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
NPIVPRRQFEIVQQQYPDMPHYEVDGNRVKIPAAWMIDRCGWKGKQIGRAGVHSKQALVL
CCCCCHHHHHHHHHHCCCCCCEEECCCEEEECHHHHHHHCCCCCCCCCCCCCCCCCEEEE
VNCGGATGDEVIALARRIQESVLQKFGVAISPEVNFI
EECCCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCC
>Mature Secondary Structure
MKEIKDYSLLPHNTFGMDVKASLFVEYESVTELQSILSDKNLMAGNWLHIGGGSNLLFKG
CCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEC
DYAGTVLHSAIRGYEVVAENEQEIEVRAGAGEVWDDFVAYTVKNSWYGAENLSLIPGEVG
CCHHHHHHHHHCCEEEEECCCCEEEEECCCCHHHHHHEEEEEECCCCCCCCCEECCCCCC
ASAVQNIGAYGVEAKDLIVSVETVEVETGRKRIFTKEECRYAYRESIFKKDLKGKYIVTY
HHHHHHCCCCCCCHHHEEEEEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEE
VTYRLSKQPVFNLEYGNVRGELEKRGGEVALENVRKVIIAVREAKLPDPRVQGNAGSFFM
EEEEECCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
NPIVPRRQFEIVQQQYPDMPHYEVDGNRVKIPAAWMIDRCGWKGKQIGRAGVHSKQALVL
CCCCCHHHHHHHHHHCCCCCCEEECCCEEEECHHHHHHHCCCCCCCCCCCCCCCCCEEEE
VNCGGATGDEVIALARRIQESVLQKFGVAISPEVNFI
EECCCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA