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The map label for this gene is btuC [H]

Identifier: 150004597

GI number: 150004597

Start: 2662573

End: 2663604

Strand: Reverse

Name: btuC [H]

Synonym: BVU_2054

Alternate gene names: 150004597

Gene position: 2663604-2662573 (Counterclockwise)

Preceding gene: 150004598

Following gene: 150004596

Centisome position: 51.59

GC content: 50.48

Gene sequence:

>1032_bases
ATGAATAACAAAGGAACAAAATACGGTATCATACTGCTCCTTCTCATCCTTGCATTGACAGGAGCCAACCTGTTGTTCGG
TTCGGTAAACATCCCTGCCGATGCGGTGTGGCATATCCTTACAGGCAATGAAGTAGAAAAGGCGAGTTGGAGTTTCATAG
TCTGGGAATCCCGTCTGCCGCAAGCCATTACCGCCCTCCTTTGCGGAATGGCACTCGCAGCATCGGGACTGATGTTGCAA
ACCACATTCAATAACCCTTTGGCCGACCCTTCCATACTGGGAATCAGTTCGGGAGCCAGTTTGGGAGTTGCCTTGGTCAT
GCTGGCAGGCGCAGGTACGATTACTGCCGGAGTATTCACTTTATCCGGATTCCTGTCCGTCATTATCGGAGCATTCATAG
GCTCCATGCTGGTGATGGGAATCATCCTGTTCTTCTCCACTTTGATAAAAAACAGCATCATGCTGCTCATTATAGGTATC
ATGATAGGGTATATCACTTCATCTGCCATCTCCCTGCTCAACTTTTTCTCCACGGCAGAAGGGGTGCATTCCTACATGAT
TTGGGGAATGGGAAACTTTGGAGGAGTATCTTTGCAGCAGCTTCCCTTTTTCTCCTTGGTCACAATGGCGGGACTGCTGA
TTACCATACTGCTGATAAAGCCTCTGAATGCCCTGCTGCTGGGAACACGCTATGCCGAAAACCTGGGAATCAACATCCGC
CGTACACGTAACCTGCTGCTTGTCGCCACCGGATTACTGACAGCGACGACTACCGCTTTCTGCGGCCCGATTTCCTTTAT
CGGACTGGCTGTGCCGCACATTGCCCGCCTCATGCTGGGAACCTCCAACCATAACTCTCTGCTACCTGTCACCATGCTGA
CGGGAGGAGCCATTGCCCTGCTCTGCAACTTCATCTGCATTCTGCCGGGCGAGGCAGGTATCATTCCACTGAATGCCGTC
ACTCCGGTCATCGGTGCGCCCATTATTATTTATGTCATTGTGAACCAACGTAAAATCCAGTACTTCAACTGA

Upstream 100 bases:

>100_bases
TGTCAAAACGTGGATAATGCTGCCCCTACAGCTGACGATAGGATAGGCCGGGTTAGTTTTGACACACTCCCTACAGTGGG
CGTACCCCCAAACAGTATCA

Downstream 100 bases:

>100_bases
TGGAAAAGCAAGCTGTCATCACCGCCACAGACCTGTGCATAGGTTATCGTACCCACAAAGGAGAAAAGAAAGTGCACGAA
CACCTTTCTTTCGGACTCTA

Product: iron(III) ABC transporter putative permease protein

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNNKGTKYGIILLLLILALTGANLLFGSVNIPADAVWHILTGNEVEKASWSFIVWESRLPQAITALLCGMALAASGLMLQ
TTFNNPLADPSILGISSGASLGVALVMLAGAGTITAGVFTLSGFLSVIIGAFIGSMLVMGIILFFSTLIKNSIMLLIIGI
MIGYITSSAISLLNFFSTAEGVHSYMIWGMGNFGGVSLQQLPFFSLVTMAGLLITILLIKPLNALLLGTRYAENLGINIR
RTRNLLLVATGLLTATTTAFCGPISFIGLAVPHIARLMLGTSNHNSLLPVTMLTGGAIALLCNFICILPGEAGIIPLNAV
TPVIGAPIIIYVIVNQRKIQYFN

Sequences:

>Translated_343_residues
MNNKGTKYGIILLLLILALTGANLLFGSVNIPADAVWHILTGNEVEKASWSFIVWESRLPQAITALLCGMALAASGLMLQ
TTFNNPLADPSILGISSGASLGVALVMLAGAGTITAGVFTLSGFLSVIIGAFIGSMLVMGIILFFSTLIKNSIMLLIIGI
MIGYITSSAISLLNFFSTAEGVHSYMIWGMGNFGGVSLQQLPFFSLVTMAGLLITILLIKPLNALLLGTRYAENLGINIR
RTRNLLLVATGLLTATTTAFCGPISFIGLAVPHIARLMLGTSNHNSLLPVTMLTGGAIALLCNFICILPGEAGIIPLNAV
TPVIGAPIIIYVIVNQRKIQYFN
>Mature_343_residues
MNNKGTKYGIILLLLILALTGANLLFGSVNIPADAVWHILTGNEVEKASWSFIVWESRLPQAITALLCGMALAASGLMLQ
TTFNNPLADPSILGISSGASLGVALVMLAGAGTITAGVFTLSGFLSVIIGAFIGSMLVMGIILFFSTLIKNSIMLLIIGI
MIGYITSSAISLLNFFSTAEGVHSYMIWGMGNFGGVSLQQLPFFSLVTMAGLLITILLIKPLNALLLGTRYAENLGINIR
RTRNLLLVATGLLTATTTAFCGPISFIGLAVPHIARLMLGTSNHNSLLPVTMLTGGAIALLCNFICILPGEAGIIPLNAV
TPVIGAPIIIYVIVNQRKIQYFN

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=35.0877192982456, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790740, Length=341, Percent_Identity=30.2052785923754, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786805, Length=324, Percent_Identity=30.8641975308642, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790741, Length=285, Percent_Identity=34.0350877192982, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786804, Length=257, Percent_Identity=31.1284046692607, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=29.9651567944251, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36124; Mature: 36124

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKGTKYGIILLLLILALTGANLLFGSVNIPADAVWHILTGNEVEKASWSFIVWESRLP
CCCCCCHHHHHHHHHHHHHCCCHHEEECCCCCHHHHEEEECCCCCCCCCCEEEEECHHCH
QAITALLCGMALAASGLMLQTTFNNPLADPSILGISSGASLGVALVMLAGAGTITAGVFT
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHH
LSGFLSVIIGAFIGSMLVMGIILFFSTLIKNSIMLLIIGIMIGYITSSAISLLNFFSTAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVHSYMIWGMGNFGGVSLQQLPFFSLVTMAGLLITILLIKPLNALLLGTRYAENLGINIR
HHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
RTRNLLLVATGLLTATTTAFCGPISFIGLAVPHIARLMLGTSNHNSLLPVTMLTGGAIAL
ECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHCCCHHHH
LCNFICILPGEAGIIPLNAVTPVIGAPIIIYVIVNQRKIQYFN
HHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEEEECCCEEECCC
>Mature Secondary Structure
MNNKGTKYGIILLLLILALTGANLLFGSVNIPADAVWHILTGNEVEKASWSFIVWESRLP
CCCCCCHHHHHHHHHHHHHCCCHHEEECCCCCHHHHEEEECCCCCCCCCCEEEEECHHCH
QAITALLCGMALAASGLMLQTTFNNPLADPSILGISSGASLGVALVMLAGAGTITAGVFT
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHH
LSGFLSVIIGAFIGSMLVMGIILFFSTLIKNSIMLLIIGIMIGYITSSAISLLNFFSTAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVHSYMIWGMGNFGGVSLQQLPFFSLVTMAGLLITILLIKPLNALLLGTRYAENLGINIR
HHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
RTRNLLLVATGLLTATTTAFCGPISFIGLAVPHIARLMLGTSNHNSLLPVTMLTGGAIAL
ECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHCCCHHHH
LCNFICILPGEAGIIPLNAVTPVIGAPIIIYVIVNQRKIQYFN
HHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA