Click here to switch to the map view.

The map label for this gene is gph [C]

Identifier: 150004522

GI number: 150004522

Start: 2552629

End: 2553282

Strand: Reverse

Name: gph [C]

Synonym: BVU_1972

Alternate gene names: 150004522

Gene position: 2553282-2552629 (Counterclockwise)

Preceding gene: 150004527

Following gene: 150004520

Centisome position: 49.45

GC content: 43.58

Gene sequence:

>654_bases
ATGAAGAAACTTGTAATATTCGACCTGGACGGCACATTACTGAACACCATTGCCGACCTGGCTGCCGCCACCAACCAAGC
CTTACAATATTATGGCTATCCTACACATGAAACGGAAGCATACCGCTTTTTTGTAGGAAACGGAATCAATAAATTATTTG
AGCGTGCTCTGCCTGAAGGGGAACGTACGGAAGAGAATGTATTAAAGATACGTTCACAATTCATCCCTTATTATGATGAG
CACAATGCCGATTTAAGCCGCCCTTATCCCGGTATCTCCGAATTATTAAAAACACTGCAACAGCAAGGGATCATGATAGC
GGTCGCCTCCAATAAATACCAAGCAGCTACCCGAAAGTTAATAGCACACTATTTTCCAGAAATAAACTTTGTGGAAGTAC
TGGGACAACGCGAAGGTATCCCCGCAAAACCCGATCCATCCATCATAAACGAAATCATGACAAAAGCAGGAGTCAAACAG
GAAGATATACTTTATGTAGGTGATTCTAATGTAGATATGCAAACAGCGCATCATGCCGGAGTAACAGCTATAGGTGTGGC
ATGGGGATTCCGGCCGCGCACAGAATTGGAAGCCTTACATCCGGCACATATCATAGAAAAAGCAGAAGAATTACTTCCGC
TTCTCCTTTCATGA

Upstream 100 bases:

>100_bases
GCAGAATAGCGCGCCTTCACTAATTCTAGAAAGTTCATAAGCATTATTATTAGTTTGCATACAAAAATAGTAACTTTGCA
CCGATAAAAGAAGTACAAAT

Downstream 100 bases:

>100_bases
TTATTTTCATTAAATAGATAATTCATCAAGCACCTTGATAAGCGATTTATCAAGGGGCTTGTCTTTTTTAATTGCCTCAG
AAAAAGGTACATATACCACC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKKLVIFDLDGTLLNTIADLAAATNQALQYYGYPTHETEAYRFFVGNGINKLFERALPEGERTEENVLKIRSQFIPYYDE
HNADLSRPYPGISELLKTLQQQGIMIAVASNKYQAATRKLIAHYFPEINFVEVLGQREGIPAKPDPSIINEIMTKAGVKQ
EDILYVGDSNVDMQTAHHAGVTAIGVAWGFRPRTELEALHPAHIIEKAEELLPLLLS

Sequences:

>Translated_217_residues
MKKLVIFDLDGTLLNTIADLAAATNQALQYYGYPTHETEAYRFFVGNGINKLFERALPEGERTEENVLKIRSQFIPYYDE
HNADLSRPYPGISELLKTLQQQGIMIAVASNKYQAATRKLIAHYFPEINFVEVLGQREGIPAKPDPSIINEIMTKAGVKQ
EDILYVGDSNVDMQTAHHAGVTAIGVAWGFRPRTELEALHPAHIIEKAEELLPLLLS
>Mature_217_residues
MKKLVIFDLDGTLLNTIADLAAATNQALQYYGYPTHETEAYRFFVGNGINKLFERALPEGERTEENVLKIRSQFIPYYDE
HNADLSRPYPGISELLKTLQQQGIMIAVASNKYQAATRKLIAHYFPEINFVEVLGQREGIPAKPDPSIINEIMTKAGVKQ
EDILYVGDSNVDMQTAHHAGVTAIGVAWGFRPRTELEALHPAHIIEKAEELLPLLLS

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=230, Percent_Identity=28.2608695652174, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24306; Mature: 24306

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVIFDLDGTLLNTIADLAAATNQALQYYGYPTHETEAYRFFVGNGINKLFERALPEG
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHCCCC
ERTEENVLKIRSQFIPYYDEHNADLSRPYPGISELLKTLQQQGIMIAVASNKYQAATRKL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHH
IAHYFPEINFVEVLGQREGIPAKPDPSIINEIMTKAGVKQEDILYVGDSNVDMQTAHHAG
HHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCC
VTAIGVAWGFRPRTELEALHPAHIIEKAEELLPLLLS
CEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLVIFDLDGTLLNTIADLAAATNQALQYYGYPTHETEAYRFFVGNGINKLFERALPEG
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHCCCC
ERTEENVLKIRSQFIPYYDEHNADLSRPYPGISELLKTLQQQGIMIAVASNKYQAATRKL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHH
IAHYFPEINFVEVLGQREGIPAKPDPSIINEIMTKAGVKQEDILYVGDSNVDMQTAHHAG
HHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCC
VTAIGVAWGFRPRTELEALHPAHIIEKAEELLPLLLS
CEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA