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The map label for this gene is guaD [H]

Identifier: 150004479

GI number: 150004479

Start: 2506477

End: 2506944

Strand: Reverse

Name: guaD [H]

Synonym: BVU_1928

Alternate gene names: 150004479

Gene position: 2506944-2506477 (Counterclockwise)

Preceding gene: 150004483

Following gene: 150004476

Centisome position: 48.55

GC content: 47.65

Gene sequence:

>468_bases
ATGAAGAAAGAAGAATTAATGCGGAAAGCCATTGAGCTTTCTATAGAGAATGTGGCAAACGGCGGCGGACCCTTTGGAGC
CGTAATTGCCAAAGATGGTGAAATCATTGCGACCGGAGCCAATCGTGTCACCTCACAATGCGACCCTACCGCCCATGCGG
AAGTCAGCGCCATCCGTGCGGCGGCAAGCAAACTGGGAACATTCAACTTGAGCGGATGTGAAATTTATACTTCGTGTGAA
CCGTGTCCCATGTGTCTGGGAGCCATTTACTGGGCACGGCTGGATAAAATGTATTATGCAAACAACAAGACGGATGCCAA
GAATATAGGGTTTGACGACTCTTTTATCTATGATGAGTTAAGCCTGAAACCTTCGGCACGCAAGCTGCCTTCCGAAGTTC
TTTTGGCGGAAGAGGCGATAAAGGCATTCCAACAATGGACAGAGAAAAGTGACAAAGTGGAGTATTAA

Upstream 100 bases:

>100_bases
GTACACATGAAGCGGCAGTTTCCGAATAAAATAAGCCCTCTCCCGCATATATAGCCGGAAATATCGTATATTTGCTCTGT
ACTAAAGAAATAGAACCACT

Downstream 100 bases:

>100_bases
TAGAAAGGCGCGGACGAAATCCCTATCATCCGCGCCCGAAATCTTTATAAGATATTAAAGACTATTCTTTTACCGGCGTA
TTTTCCAACGTAGCTACTAC

Product: cytidine/deoxycytidylate deaminase

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MKKEELMRKAIELSIENVANGGGPFGAVIAKDGEIIATGANRVTSQCDPTAHAEVSAIRAAASKLGTFNLSGCEIYTSCE
PCPMCLGAIYWARLDKMYYANNKTDAKNIGFDDSFIYDELSLKPSARKLPSEVLLAEEAIKAFQQWTEKSDKVEY

Sequences:

>Translated_155_residues
MKKEELMRKAIELSIENVANGGGPFGAVIAKDGEIIATGANRVTSQCDPTAHAEVSAIRAAASKLGTFNLSGCEIYTSCE
PCPMCLGAIYWARLDKMYYANNKTDAKNIGFDDSFIYDELSLKPSARKLPSEVLLAEEAIKAFQQWTEKSDKVEY
>Mature_155_residues
MKKEELMRKAIELSIENVANGGGPFGAVIAKDGEIIATGANRVTSQCDPTAHAEVSAIRAAASKLGTFNLSGCEIYTSCE
PCPMCLGAIYWARLDKMYYANNKTDAKNIGFDDSFIYDELSLKPSARKLPSEVLLAEEAIKAFQQWTEKSDKVEY

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=106, Percent_Identity=33.0188679245283, Blast_Score=67, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17554608, Length=152, Percent_Identity=46.0526315789474, Blast_Score=143, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17555996, Length=153, Percent_Identity=45.0980392156863, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 16966; Mature: 16966

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEELMRKAIELSIENVANGGGPFGAVIAKDGEIIATGANRVTSQCDPTAHAEVSAIRA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHCCCCCCCHHHHHHHHH
AASKLGTFNLSGCEIYTSCEPCPMCLGAIYWARLDKMYYANNKTDAKNIGFDDSFIYDEL
HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHC
SLKPSARKLPSEVLLAEEAIKAFQQWTEKSDKVEY
CCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKEELMRKAIELSIENVANGGGPFGAVIAKDGEIIATGANRVTSQCDPTAHAEVSAIRA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHCCCCCCCHHHHHHHHH
AASKLGTFNLSGCEIYTSCEPCPMCLGAIYWARLDKMYYANNKTDAKNIGFDDSFIYDEL
HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHC
SLKPSARKLPSEVLLAEEAIKAFQQWTEKSDKVEY
CCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]