Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 150004452

GI number: 150004452

Start: 2472470

End: 2473531

Strand: Reverse

Name: aroB [H]

Synonym: BVU_1900

Alternate gene names: 150004452

Gene position: 2473531-2472470 (Counterclockwise)

Preceding gene: 150004456

Following gene: 150004451

Centisome position: 47.91

GC content: 37.29

Gene sequence:

>1062_bases
ATGAGTAAACAAGAAGTTATTATCTGCCATAACTTAGAAGAAAATCTCAATAAGGCAATAAACCAATGCCCACATGACAA
ATTATTTGTCTTGGCTGACGAACATACACGTGAACTTTGCATTCCTGTTTTATCAGAATTTGATTGTATTAAAAATGCCC
ATTTTATTTATATAGGGGCTGAAGATGTGCACAAAAACTTGGAAACACTGGCATATGTATGGAAAGAGTTGGGAGATAAA
GGTGCAAGCCGTCATTCGCTACTTATCAATTTAGGTGGAGGGATGGTTACAGATTTAGGAGGATTCGCCGCATCAACTTT
CAAACGAGGGATCAAATATATTAATATTCCTACCACACTGCTGGCTATGGTTGATGCATCTGTAGGAGGCAAGACCGGAA
TCAATTTCAACGGATTAAAGAATGAGATCGGAGTCTTCTCTCCTGCCGAAAGTGTATTGATTGACGCTAATTTTCTAAAA
TCACTGGATATTCGCAATCTATTGTCCGGATACGCTGAAATGTTGAAACATGGTCTTATCAGCACCCATGATCATTGGAT
AGAATTGTTGAAATTTGACTTCAACAATATAGATTACAAGGTCTTACAGACTTTAGTCGGAAAATCTGTACAGATTAAAG
AAGATATAGTGGAACAGGATCCTTTTGAAAGAGGAATCCGCAAAGCTTTAAATCTGGGACACACCGTAGGGCATGCTTTT
GAAAGTCTGGCATTAGAAACACAGCATCCGATATTACATGGTTACGCTGTGGCATGGGGAATAGTTTGTGAACTTTATTT
CTCCCATATCAAAACTGGTTTTCCTAAAGACAAGCTACGTCAGACCATCCTGTTCGTCAAAGAACATTATGGAGTTATGC
CTTTTAATTGCAAACAATATGAACGCCTCTATGAATTCATGAAACATGATAAGAAAAACTCAGCAGGCATTATCAATTTC
ACCCTATTAACTGAAATAGGAAATATACAGATTAATCAATCGGCAAGTAAAGACGAAATTTTTGAAATGCTGGATTTTTA
TCATGAATCCATGGGTTGCTGA

Upstream 100 bases:

>100_bases
CATTATTTTATATTTTAACGTACAAAAGTAATTATTTGTAAGCAAAGAACGGTCATCTTTTTGCTTTTTTACCTAAATTT
GCAGGCAAATAATAGAAAAT

Downstream 100 bases:

>100_bases
TCTCCCTTCAAACAGATGGAAAGGATTATACAAACTTTCCATCTGTCCGATACAATAAAAACATCTTTTATTTATTCCCA
ATTATAATCGATCAAACTTT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSKQEVIICHNLEENLNKAINQCPHDKLFVLADEHTRELCIPVLSEFDCIKNAHFIYIGAEDVHKNLETLAYVWKELGDK
GASRHSLLINLGGGMVTDLGGFAASTFKRGIKYINIPTTLLAMVDASVGGKTGINFNGLKNEIGVFSPAESVLIDANFLK
SLDIRNLLSGYAEMLKHGLISTHDHWIELLKFDFNNIDYKVLQTLVGKSVQIKEDIVEQDPFERGIRKALNLGHTVGHAF
ESLALETQHPILHGYAVAWGIVCELYFSHIKTGFPKDKLRQTILFVKEHYGVMPFNCKQYERLYEFMKHDKKNSAGIINF
TLLTEIGNIQINQSASKDEIFEMLDFYHESMGC

Sequences:

>Translated_353_residues
MSKQEVIICHNLEENLNKAINQCPHDKLFVLADEHTRELCIPVLSEFDCIKNAHFIYIGAEDVHKNLETLAYVWKELGDK
GASRHSLLINLGGGMVTDLGGFAASTFKRGIKYINIPTTLLAMVDASVGGKTGINFNGLKNEIGVFSPAESVLIDANFLK
SLDIRNLLSGYAEMLKHGLISTHDHWIELLKFDFNNIDYKVLQTLVGKSVQIKEDIVEQDPFERGIRKALNLGHTVGHAF
ESLALETQHPILHGYAVAWGIVCELYFSHIKTGFPKDKLRQTILFVKEHYGVMPFNCKQYERLYEFMKHDKKNSAGIINF
TLLTEIGNIQINQSASKDEIFEMLDFYHESMGC
>Mature_352_residues
SKQEVIICHNLEENLNKAINQCPHDKLFVLADEHTRELCIPVLSEFDCIKNAHFIYIGAEDVHKNLETLAYVWKELGDKG
ASRHSLLINLGGGMVTDLGGFAASTFKRGIKYINIPTTLLAMVDASVGGKTGINFNGLKNEIGVFSPAESVLIDANFLKS
LDIRNLLSGYAEMLKHGLISTHDHWIELLKFDFNNIDYKVLQTLVGKSVQIKEDIVEQDPFERGIRKALNLGHTVGHAFE
SLALETQHPILHGYAVAWGIVCELYFSHIKTGFPKDKLRQTILFVKEHYGVMPFNCKQYERLYEFMKHDKKNSAGIINFT
LLTEIGNIQINQSASKDEIFEMLDFYHESMGC

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=289, Percent_Identity=35.6401384083045, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320332, Length=237, Percent_Identity=33.7552742616034, Blast_Score=126, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39862; Mature: 39731

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQEVIICHNLEENLNKAINQCPHDKLFVLADEHTRELCIPVLSEFDCIKNAHFIYIGA
CCCCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEH
EDVHKNLETLAYVWKELGDKGASRHSLLINLGGGMVTDLGGFAASTFKRGIKYINIPTTL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEECHHHH
LAMVDASVGGKTGINFNGLKNEIGVFSPAESVLIDANFLKSLDIRNLLSGYAEMLKHGLI
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHEECHHHHHHHHHHHHHHHHHHHHHHCCC
STHDHWIELLKFDFNNIDYKVLQTLVGKSVQIKEDIVEQDPFERGIRKALNLGHTVGHAF
CCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ESLALETQHPILHGYAVAWGIVCELYFSHIKTGFPKDKLRQTILFVKEHYGVMPFNCKQY
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
ERLYEFMKHDKKNSAGIINFTLLTEIGNIQINQSASKDEIFEMLDFYHESMGC
HHHHHHHHCCCCCCCCEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKQEVIICHNLEENLNKAINQCPHDKLFVLADEHTRELCIPVLSEFDCIKNAHFIYIGA
CCCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEH
EDVHKNLETLAYVWKELGDKGASRHSLLINLGGGMVTDLGGFAASTFKRGIKYINIPTTL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEECHHHH
LAMVDASVGGKTGINFNGLKNEIGVFSPAESVLIDANFLKSLDIRNLLSGYAEMLKHGLI
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHEECHHHHHHHHHHHHHHHHHHHHHHCCC
STHDHWIELLKFDFNNIDYKVLQTLVGKSVQIKEDIVEQDPFERGIRKALNLGHTVGHAF
CCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ESLALETQHPILHGYAVAWGIVCELYFSHIKTGFPKDKLRQTILFVKEHYGVMPFNCKQY
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
ERLYEFMKHDKKNSAGIINFTLLTEIGNIQINQSASKDEIFEMLDFYHESMGC
HHHHHHHHCCCCCCCCEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA