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The map label for this gene is yfnA [H]

Identifier: 150004414

GI number: 150004414

Start: 2427942

End: 2429600

Strand: Reverse

Name: yfnA [H]

Synonym: BVU_1861

Alternate gene names: 150004414

Gene position: 2429600-2427942 (Counterclockwise)

Preceding gene: 150004415

Following gene: 150004411

Centisome position: 47.06

GC content: 45.21

Gene sequence:

>1659_bases
ATGGGATTATTTATCAAGAAGCCTTTTGCTGCATTACAAGCCGAAGCCAATGAATCTGGAAACAAGACCCTGAAAAGAGT
CTTGGGACCATGGAGCTTGATCGCATTAGGAGTAGGTGTTATCATCGGTGCCGGATTATTCTCCATCACCGGAACAGTAG
CCGCAGGATACACAGGGCCTGCCATTACTTTATCTTTCGCCATAGCGGCAATAGGTTGTTGCTTTGCCGGTTTATGTTAT
GCCGAGTTTGCTTCCATGATACCTGTAGCAGGTAGTGCTTATACATACTCATATGCTACAATGGGCGAACTTATAGCATG
GATTATCGGCTGGGATCTAGTATTGGAATATACTGTTGCCGCTACTACCGTCAGTATCAGCTGGAGCAGATATCTCGTTG
TTTTTCTGGAAGGAGTGGGGATAAATATCCCCCATGCACTTGCTGCTTGTCCCTGGGACGGAGGTATTGTGAATATACCA
GCCGCACTGATTGTAGTGCTGATGAGTATTTTTCTGATTCGTGGAACAGAAGGAAGTTCTATCTTTAACGGCTTCATTGT
GTTCCTGAAAGTGGCAGTGATTCTTATTTTCGTTGTATTAGGATGGAAATACATTAATGCAGAGAATTATGTTCCTTATA
TCCCTGCCAATACTGGTACTTTAGGCGAGTTCGGATTCTCGGGTGTATTGCGTGGAGCAGCGATTGTATTTTTCGCCTTT
CTTGGTTTTGATGCCGTAAGTACAGCCGCTCAGGAAACAAAAAATCCGAAACGGGATATGCCCGTCGGCATTCTAGGTTC
CCTGCTGATTTGCACCATTCTTTATATGGTGTTTGCTTACGTAATGACGGGAGTTGCCCATTATTCTGACTTTGCAGGAC
AACAAGGTATCGCACCTGTTGCCGTAGCGATTGACCACATGGGACATGCAGATGCCACAGGAGTAATTCATCCGGATTAT
CCGTGGTTGAACCGGGCCATCGTACTGGCTATCCTGTTTGGTTACTGCTCGGTTATTATGGTAACTTTGCTAGGACAAAG
CCGTGTATTTCTAAGTATGAGCCGCGACGGACTGTTGCCTCCTTTCTTTTCAAAGATTCACGAGAAATACCGGACACCGG
CACACAGTAATTTGTTATTCATGGTCATTGTAGGAGGGCTGGCAGCATTTGTTCCGGCACGTGTAGCCGGAGAAATGACC
AGTATAGGTACCTTATTCGCCTTCACATTGGTTTGCGCGGCAGTATTGATCGTGCGTAAAAGTATGCCTGACGTACATCG
TGCCTTTAAAACTCCTTTTGTTCCCACGGTACCGATTTTAGGCATCCTTACCTGCCTTTGTATGATGTTGTTTCTTCCGG
CTGACACTTGGATCCGATTGGTATTATGGATGCTGATAGGTCTGGATGTTTATGCCTGCTATGGAGTAAAACACAGCAAG
CTGGAGCATAACGTAAAACGACGCAAAGGACTCACCATATTGAATATGACAGGAATCGCCCTGTCTGTACTTTCAGTTAT
TACAGGATTGTGGCATCAACAGACAGTAGGCTGGGAAGAAGACAAGACATTGCTCGCTATTTCGTTCGTCTTTGCGTTCA
CACATTGCGCATTCTATATGGTACGTATCTGGAAACAGACATCCGAGAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
TATCTCGAATAATCGTTATAGCCTTTACTTATAGCTTGTAATTCAGGGCAGTTATCCGTACCTTTGCACACAATTATCAC
TAAATATGTTGTAAAAAGAT

Downstream 100 bases:

>100_bases
GCGTTTTCCACACGCTATCTGTTTCCATAACTTTCATTCACCGTAAGGGGTAAATTCAATCCACCCCCTACCGTGAATAA
AGTTATCATAGTTTCATACC

Product: cationic amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MGLFIKKPFAALQAEANESGNKTLKRVLGPWSLIALGVGVIIGAGLFSITGTVAAGYTGPAITLSFAIAAIGCCFAGLCY
AEFASMIPVAGSAYTYSYATMGELIAWIIGWDLVLEYTVAATTVSISWSRYLVVFLEGVGINIPHALAACPWDGGIVNIP
AALIVVLMSIFLIRGTEGSSIFNGFIVFLKVAVILIFVVLGWKYINAENYVPYIPANTGTLGEFGFSGVLRGAAIVFFAF
LGFDAVSTAAQETKNPKRDMPVGILGSLLICTILYMVFAYVMTGVAHYSDFAGQQGIAPVAVAIDHMGHADATGVIHPDY
PWLNRAIVLAILFGYCSVIMVTLLGQSRVFLSMSRDGLLPPFFSKIHEKYRTPAHSNLLFMVIVGGLAAFVPARVAGEMT
SIGTLFAFTLVCAAVLIVRKSMPDVHRAFKTPFVPTVPILGILTCLCMMLFLPADTWIRLVLWMLIGLDVYACYGVKHSK
LEHNVKRRKGLTILNMTGIALSVLSVITGLWHQQTVGWEEDKTLLAISFVFAFTHCAFYMVRIWKQTSEKKK

Sequences:

>Translated_552_residues
MGLFIKKPFAALQAEANESGNKTLKRVLGPWSLIALGVGVIIGAGLFSITGTVAAGYTGPAITLSFAIAAIGCCFAGLCY
AEFASMIPVAGSAYTYSYATMGELIAWIIGWDLVLEYTVAATTVSISWSRYLVVFLEGVGINIPHALAACPWDGGIVNIP
AALIVVLMSIFLIRGTEGSSIFNGFIVFLKVAVILIFVVLGWKYINAENYVPYIPANTGTLGEFGFSGVLRGAAIVFFAF
LGFDAVSTAAQETKNPKRDMPVGILGSLLICTILYMVFAYVMTGVAHYSDFAGQQGIAPVAVAIDHMGHADATGVIHPDY
PWLNRAIVLAILFGYCSVIMVTLLGQSRVFLSMSRDGLLPPFFSKIHEKYRTPAHSNLLFMVIVGGLAAFVPARVAGEMT
SIGTLFAFTLVCAAVLIVRKSMPDVHRAFKTPFVPTVPILGILTCLCMMLFLPADTWIRLVLWMLIGLDVYACYGVKHSK
LEHNVKRRKGLTILNMTGIALSVLSVITGLWHQQTVGWEEDKTLLAISFVFAFTHCAFYMVRIWKQTSEKKK
>Mature_551_residues
GLFIKKPFAALQAEANESGNKTLKRVLGPWSLIALGVGVIIGAGLFSITGTVAAGYTGPAITLSFAIAAIGCCFAGLCYA
EFASMIPVAGSAYTYSYATMGELIAWIIGWDLVLEYTVAATTVSISWSRYLVVFLEGVGINIPHALAACPWDGGIVNIPA
ALIVVLMSIFLIRGTEGSSIFNGFIVFLKVAVILIFVVLGWKYINAENYVPYIPANTGTLGEFGFSGVLRGAAIVFFAFL
GFDAVSTAAQETKNPKRDMPVGILGSLLICTILYMVFAYVMTGVAHYSDFAGQQGIAPVAVAIDHMGHADATGVIHPDYP
WLNRAIVLAILFGYCSVIMVTLLGQSRVFLSMSRDGLLPPFFSKIHEKYRTPAHSNLLFMVIVGGLAAFVPARVAGEMTS
IGTLFAFTLVCAAVLIVRKSMPDVHRAFKTPFVPTVPILGILTCLCMMLFLPADTWIRLVLWMLIGLDVYACYGVKHSKL
EHNVKRRKGLTILNMTGIALSVLSVITGLWHQQTVGWEEDKTLLAISFVFAFTHCAFYMVRIWKQTSEKKK

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=427, Percent_Identity=32.7868852459016, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI114326544, Length=432, Percent_Identity=32.4074074074074, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI114326550, Length=432, Percent_Identity=32.4074074074074, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI258645169, Length=430, Percent_Identity=32.3255813953488, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI258614003, Length=551, Percent_Identity=29.4010889292196, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI258614005, Length=551, Percent_Identity=29.4010889292196, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI181337167, Length=417, Percent_Identity=32.8537170263789, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI110347453, Length=411, Percent_Identity=31.1435523114355, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI7657683, Length=410, Percent_Identity=23.6585365853659, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI186910308, Length=442, Percent_Identity=25.1131221719457, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI186910306, Length=442, Percent_Identity=25.1131221719457, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI186910304, Length=442, Percent_Identity=25.1131221719457, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI115648063, Length=362, Percent_Identity=24.585635359116, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI115648022, Length=362, Percent_Identity=24.585635359116, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI187423910, Length=495, Percent_Identity=21.8181818181818, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI7657591, Length=495, Percent_Identity=21.8181818181818, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI71979932, Length=218, Percent_Identity=28.8990825688073, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082023, Length=469, Percent_Identity=25.7995735607676, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87081869, Length=476, Percent_Identity=22.6890756302521, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87082250, Length=474, Percent_Identity=25.5274261603376, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081708, Length=493, Percent_Identity=24.7464503042596, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790653, Length=247, Percent_Identity=26.7206477732794, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1786694, Length=435, Percent_Identity=22.7586206896552, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI2367353, Length=461, Percent_Identity=21.9088937093275, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=401, Percent_Identity=31.9201995012469, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17531343, Length=415, Percent_Identity=30.6024096385542, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17533459, Length=424, Percent_Identity=29.0094339622642, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17540018, Length=496, Percent_Identity=23.991935483871, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17568033, Length=482, Percent_Identity=25.5186721991701, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71993915, Length=424, Percent_Identity=23.1132075471698, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71995382, Length=427, Percent_Identity=22.9508196721311, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71995388, Length=427, Percent_Identity=22.9508196721311, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32566699, Length=358, Percent_Identity=22.0670391061453, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666159, Length=433, Percent_Identity=33.7182448036951, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI221512776, Length=433, Percent_Identity=33.7182448036951, Blast_Score=226, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24667468, Length=424, Percent_Identity=32.311320754717, Blast_Score=205, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24668806, Length=445, Percent_Identity=32.8089887640449, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21356285, Length=445, Percent_Identity=32.8089887640449, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24668802, Length=445, Percent_Identity=32.8089887640449, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI281366235, Length=420, Percent_Identity=33.3333333333333, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI116007820, Length=420, Percent_Identity=33.3333333333333, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI116007818, Length=420, Percent_Identity=33.0952380952381, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI85725152, Length=420, Percent_Identity=33.0952380952381, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI161077963, Length=424, Percent_Identity=29.7169811320755, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21357367, Length=445, Percent_Identity=25.3932584269663, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221331183, Length=468, Percent_Identity=24.3589743589744, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17647653, Length=468, Percent_Identity=24.3589743589744, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24664379, Length=468, Percent_Identity=24.3589743589744, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 59784; Mature: 59653

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFIKKPFAALQAEANESGNKTLKRVLGPWSLIALGVGVIIGAGLFSITGTVAAGYTGP
CCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AITLSFAIAAIGCCFAGLCYAEFASMIPVAGSAYTYSYATMGELIAWIIGWDLVLEYTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
ATTVSISWSRYLVVFLEGVGINIPHALAACPWDGGIVNIPAALIVVLMSIFLIRGTEGSS
HHEEEEEHHHEEEEEEECCCCCCCHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCH
IFNGFIVFLKVAVILIFVVLGWKYINAENYVPYIPANTGTLGEFGFSGVLRGAAIVFFAF
HHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHH
LGFDAVSTAAQETKNPKRDMPVGILGSLLICTILYMVFAYVMTGVAHYSDFAGQQGIAPV
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AVAIDHMGHADATGVIHPDYPWLNRAIVLAILFGYCSVIMVTLLGQSRVFLSMSRDGLLP
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
PFFSKIHEKYRTPAHSNLLFMVIVGGLAAFVPARVAGEMTSIGTLFAFTLVCAAVLIVRK
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMPDVHRAFKTPFVPTVPILGILTCLCMMLFLPADTWIRLVLWMLIGLDVYACYGVKHSK
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
LEHNVKRRKGLTILNMTGIALSVLSVITGLWHQQTVGWEEDKTLLAISFVFAFTHCAFYM
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
VRIWKQTSEKKK
HHHHHHHHCCCC
>Mature Secondary Structure 
GLFIKKPFAALQAEANESGNKTLKRVLGPWSLIALGVGVIIGAGLFSITGTVAAGYTGP
CCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AITLSFAIAAIGCCFAGLCYAEFASMIPVAGSAYTYSYATMGELIAWIIGWDLVLEYTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
ATTVSISWSRYLVVFLEGVGINIPHALAACPWDGGIVNIPAALIVVLMSIFLIRGTEGSS
HHEEEEEHHHEEEEEEECCCCCCCHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCH
IFNGFIVFLKVAVILIFVVLGWKYINAENYVPYIPANTGTLGEFGFSGVLRGAAIVFFAF
HHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHH
LGFDAVSTAAQETKNPKRDMPVGILGSLLICTILYMVFAYVMTGVAHYSDFAGQQGIAPV
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AVAIDHMGHADATGVIHPDYPWLNRAIVLAILFGYCSVIMVTLLGQSRVFLSMSRDGLLP
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
PFFSKIHEKYRTPAHSNLLFMVIVGGLAAFVPARVAGEMTSIGTLFAFTLVCAAVLIVRK
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMPDVHRAFKTPFVPTVPILGILTCLCMMLFLPADTWIRLVLWMLIGLDVYACYGVKHSK
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
LEHNVKRRKGLTILNMTGIALSVLSVITGLWHQQTVGWEEDKTLLAISFVFAFTHCAFYM
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
VRIWKQTSEKKK
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]