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The map label for this gene is cocE [H]

Identifier: 150004411

GI number: 150004411

Start: 2421821

End: 2423728

Strand: Reverse

Name: cocE [H]

Synonym: BVU_1858

Alternate gene names: 150004411

Gene position: 2423728-2421821 (Counterclockwise)

Preceding gene: 150004414

Following gene: 150004399

Centisome position: 46.94

GC content: 42.09

Gene sequence:

>1908_bases
ATGAAAAGATTAGGCAAATTCTTATTTATTACTTCATTACTGTTATGCTTTCTCATCCCTCGAGGATGGACACAAACCCA
AGCAAAAAACCAACCGGACAGTATCGAACTCAAACTGAAGGAAATCTACACGAAACGGGAAGTCATGATTCCCATGCGTG
ACGGAATCAAGCTTTACACCGCTGTCTACGAACCGAAAGACAACAGCAGGCAGCATCCTATCCTGATGCACCGCAGCCCT
TACTCTTGTTCCCCATACGGAGAAGGATTTGACCGTCATTTCAGAACTAATCTGAAAAACTATATAGAGCACCGATATAT
TATCGTCTTCCAAGATGTACGTGGACGACATAAGAGTGAAGGAATATTTATCCAAGTACGCCCTCTCAACAAAAACAAAA
AGGGTAAGAAAGATAAAAAGAATATAGACGAAGCTACGGACACATACGATACCATAGAATGGTTGATTCACAACACATAT
AATAACGGAAATGTAGGAACATGGGGAATCAGTTATGATGGTTTCTATGCCACTATGACAGCCTCCTCCAATCATCCGGC
TTTGAAAGCTGTTTCTCCGCAAGCTCCCGTTACTGACTGGTTCCGTGGAGATGACCGTCATCACAACGGAGCCTTCACCC
TGCTGCAAACCACTAATTTCCTTCCCAGACTGGAAGGACGCCACATGGGAAAAGGAGTGATGAACCAAATTGTAAAGAAT
GATGTTTACACAGATTTTCTGGCACTCGGTACCTTTAAGAATGTAGACGACCTGGTACGTGATACCACACAGACATTGTG
GAATGATATCAAAAACCATCCTGATTTCGATGATTTCTGGAAAGAGCGCGATGCACGCACCTCCTGTTATAACTTGAAGC
CAGCCATATTGGTGGTAGGTGGACTGTATGACTCCGAAGACTGTTACGGAGCCTGGAATCTTTATAAAGCCATCAAAGAG
CAATCACCGGACACAGATTTATATCTGACATTCGGTCCTTGGTGGCATGGAGCATGGACAGTACGCGGGTTCCAAGGTTT
CGGTAATCTGTATTTCGGTAAAAGCACTTCGGCTTATTACATGGACAAAATAGAATATCCTTTTTTCCGATATTTCCTGG
AAGGAAAGGGAGAAAAGCCCAAGCATAAAGTAAATATATTCCATACAGGTGAAAACGAATGGAAAACATACAACGAATGG
CCTGTACAAAAGACTGCCGGTACACCTTATTATATACATAAAAACGGATCAGTATCCACACAAGCACCGGCAGAACAAGA
GTCTTATTCAGAATATATTTCAGATATGTCACATCCGGTACCCTATACGGCAAACCCTACCACTTACCGGACAAAAGAAT
TCATGGTAGATGACCAACGCTTTGCTACTTCACGTCCCGATGTCATTACTTTCATGACGGAGCCGCTATGTGATACATTA
ACATTGGCCGGTCCTATAGAAGTGGAATTAATGACTGCCATCAGTAGTACTGACGCTGATTTTATGGTGAAAGTAATTGA
TGTATATCCTGAAAAATTTGAATATTCCAAAACTGCACGCAGTTATTTAAAGAGTGACTACCCAATGAGTGGGTACCAGC
TGATGATTCGTGGCGAATTATTCAGAGGACGCTTCCGTAAGGGATTCGACAATCCCCTGCCTTTCAAACCGGAAGAAATA
ACTCCGGTTAATTACACACTGTATGATGTGGCACACACATTCCTGCCGGGACACAGACTGATGATTCAAATTCAAAGTTC
CTGGTTCCCCATTATTGACCGCAATCCACAAAGGTTTATTGATACCTATCATTGTACGGTAGAAGATTTTGTGATGAAAC
AAAAGATCAAAATTTATCATCAGCAAGGAGCTGCAAGCAGAGTTATACTACCTGTGGTAAAAAAATAA

Upstream 100 bases:

>100_bases
AAGGTAGTAACTATTATCGAAATTTTTCCTTAATTAGCGTGAAAACTTTCAAGGAATGTCCTTACCTTTGCCAACTCATT
AAAATAACATCACATTATAC

Downstream 100 bases:

>100_bases
AAAGGAAGTATCCCAACAAGCTCAAATGTCATCCAATAGCAAGAGCCGTATGACTACTCCAGCATTCATACGGCTCTTTT
TATATGTAACTACCATCTGT

Product: glutaryl-7-ACA acylase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MKRLGKFLFITSLLLCFLIPRGWTQTQAKNQPDSIELKLKEIYTKREVMIPMRDGIKLYTAVYEPKDNSRQHPILMHRSP
YSCSPYGEGFDRHFRTNLKNYIEHRYIIVFQDVRGRHKSEGIFIQVRPLNKNKKGKKDKKNIDEATDTYDTIEWLIHNTY
NNGNVGTWGISYDGFYATMTASSNHPALKAVSPQAPVTDWFRGDDRHHNGAFTLLQTTNFLPRLEGRHMGKGVMNQIVKN
DVYTDFLALGTFKNVDDLVRDTTQTLWNDIKNHPDFDDFWKERDARTSCYNLKPAILVVGGLYDSEDCYGAWNLYKAIKE
QSPDTDLYLTFGPWWHGAWTVRGFQGFGNLYFGKSTSAYYMDKIEYPFFRYFLEGKGEKPKHKVNIFHTGENEWKTYNEW
PVQKTAGTPYYIHKNGSVSTQAPAEQESYSEYISDMSHPVPYTANPTTYRTKEFMVDDQRFATSRPDVITFMTEPLCDTL
TLAGPIEVELMTAISSTDADFMVKVIDVYPEKFEYSKTARSYLKSDYPMSGYQLMIRGELFRGRFRKGFDNPLPFKPEEI
TPVNYTLYDVAHTFLPGHRLMIQIQSSWFPIIDRNPQRFIDTYHCTVEDFVMKQKIKIYHQQGAASRVILPVVKK

Sequences:

>Translated_635_residues
MKRLGKFLFITSLLLCFLIPRGWTQTQAKNQPDSIELKLKEIYTKREVMIPMRDGIKLYTAVYEPKDNSRQHPILMHRSP
YSCSPYGEGFDRHFRTNLKNYIEHRYIIVFQDVRGRHKSEGIFIQVRPLNKNKKGKKDKKNIDEATDTYDTIEWLIHNTY
NNGNVGTWGISYDGFYATMTASSNHPALKAVSPQAPVTDWFRGDDRHHNGAFTLLQTTNFLPRLEGRHMGKGVMNQIVKN
DVYTDFLALGTFKNVDDLVRDTTQTLWNDIKNHPDFDDFWKERDARTSCYNLKPAILVVGGLYDSEDCYGAWNLYKAIKE
QSPDTDLYLTFGPWWHGAWTVRGFQGFGNLYFGKSTSAYYMDKIEYPFFRYFLEGKGEKPKHKVNIFHTGENEWKTYNEW
PVQKTAGTPYYIHKNGSVSTQAPAEQESYSEYISDMSHPVPYTANPTTYRTKEFMVDDQRFATSRPDVITFMTEPLCDTL
TLAGPIEVELMTAISSTDADFMVKVIDVYPEKFEYSKTARSYLKSDYPMSGYQLMIRGELFRGRFRKGFDNPLPFKPEEI
TPVNYTLYDVAHTFLPGHRLMIQIQSSWFPIIDRNPQRFIDTYHCTVEDFVMKQKIKIYHQQGAASRVILPVVKK
>Mature_635_residues
MKRLGKFLFITSLLLCFLIPRGWTQTQAKNQPDSIELKLKEIYTKREVMIPMRDGIKLYTAVYEPKDNSRQHPILMHRSP
YSCSPYGEGFDRHFRTNLKNYIEHRYIIVFQDVRGRHKSEGIFIQVRPLNKNKKGKKDKKNIDEATDTYDTIEWLIHNTY
NNGNVGTWGISYDGFYATMTASSNHPALKAVSPQAPVTDWFRGDDRHHNGAFTLLQTTNFLPRLEGRHMGKGVMNQIVKN
DVYTDFLALGTFKNVDDLVRDTTQTLWNDIKNHPDFDDFWKERDARTSCYNLKPAILVVGGLYDSEDCYGAWNLYKAIKE
QSPDTDLYLTFGPWWHGAWTVRGFQGFGNLYFGKSTSAYYMDKIEYPFFRYFLEGKGEKPKHKVNIFHTGENEWKTYNEW
PVQKTAGTPYYIHKNGSVSTQAPAEQESYSEYISDMSHPVPYTANPTTYRTKEFMVDDQRFATSRPDVITFMTEPLCDTL
TLAGPIEVELMTAISSTDADFMVKVIDVYPEKFEYSKTARSYLKSDYPMSGYQLMIRGELFRGRFRKGFDNPLPFKPEEI
TPVNYTLYDVAHTFLPGHRLMIQIQSSWFPIIDRNPQRFIDTYHCTVEDFVMKQKIKIYHQQGAASRVILPVVKK

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 73918; Mature: 73918

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLGKFLFITSLLLCFLIPRGWTQTQAKNQPDSIELKLKEIYTKREVMIPMRDGIKLYT
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHCCCEEEEECCCCEEEEE
AVYEPKDNSRQHPILMHRSPYSCSPYGEGFDRHFRTNLKNYIEHRYIIVFQDVRGRHKSE
EEECCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
GIFIQVRPLNKNKKGKKDKKNIDEATDTYDTIEWLIHNTYNNGNVGTWGISYDGFYATMT
CEEEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEEEEEE
ASSNHPALKAVSPQAPVTDWFRGDDRHHNGAFTLLQTTNFLPRLEGRHMGKGVMNQIVKN
CCCCCCCEEECCCCCCCCHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
DVYTDFLALGTFKNVDDLVRDTTQTLWNDIKNHPDFDDFWKERDARTSCYNLKPAILVVG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHCCCCCEEEEEE
GLYDSEDCYGAWNLYKAIKEQSPDTDLYLTFGPWWHGAWTVRGFQGFGNLYFGKSTSAYY
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCCEEECCCCCEEE
MDKIEYPFFRYFLEGKGEKPKHKVNIFHTGENEWKTYNEWPVQKTAGTPYYIHKNGSVST
EECCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
QAPAEQESYSEYISDMSHPVPYTANPTTYRTKEFMVDDQRFATSRPDVITFMTEPLCDTL
CCCCCHHHHHHHHHHCCCCCCCCCCCCCEECHHHEECCHHHCCCCCCEEEEECCCHHHHE
TLAGPIEVELMTAISSTDADFMVKVIDVYPEKFEYSKTARSYLKSDYPMSGYQLMIRGEL
ECCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHH
FRGRFRKGFDNPLPFKPEEITPVNYTLYDVAHTFLPGHRLMIQIQSSWFPIIDRNPQRFI
HHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCEEEEEECCCCCCEECCCHHHHH
DTYHCTVEDFVMKQKIKIYHQQGAASRVILPVVKK
HHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
>Mature Secondary Structure
MKRLGKFLFITSLLLCFLIPRGWTQTQAKNQPDSIELKLKEIYTKREVMIPMRDGIKLYT
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHCCCEEEEECCCCEEEEE
AVYEPKDNSRQHPILMHRSPYSCSPYGEGFDRHFRTNLKNYIEHRYIIVFQDVRGRHKSE
EEECCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
GIFIQVRPLNKNKKGKKDKKNIDEATDTYDTIEWLIHNTYNNGNVGTWGISYDGFYATMT
CEEEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEEEEEE
ASSNHPALKAVSPQAPVTDWFRGDDRHHNGAFTLLQTTNFLPRLEGRHMGKGVMNQIVKN
CCCCCCCEEECCCCCCCCHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
DVYTDFLALGTFKNVDDLVRDTTQTLWNDIKNHPDFDDFWKERDARTSCYNLKPAILVVG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHCCCCCEEEEEE
GLYDSEDCYGAWNLYKAIKEQSPDTDLYLTFGPWWHGAWTVRGFQGFGNLYFGKSTSAYY
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCCEEECCCCCEEE
MDKIEYPFFRYFLEGKGEKPKHKVNIFHTGENEWKTYNEWPVQKTAGTPYYIHKNGSVST
EECCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
QAPAEQESYSEYISDMSHPVPYTANPTTYRTKEFMVDDQRFATSRPDVITFMTEPLCDTL
CCCCCHHHHHHHHHHCCCCCCCCCCCCCEECHHHEECCHHHCCCCCCEEEEECCCHHHHE
TLAGPIEVELMTAISSTDADFMVKVIDVYPEKFEYSKTARSYLKSDYPMSGYQLMIRGEL
ECCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHH
FRGRFRKGFDNPLPFKPEEITPVNYTLYDVAHTFLPGHRLMIQIQSSWFPIIDRNPQRFI
HHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCEEEEEECCCCCCEECCCHHHHH
DTYHCTVEDFVMKQKIKIYHQQGAASRVILPVVKK
HHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]