Click here to switch to the map view.

The map label for this gene is pkn1 [H]

Identifier: 150004355

GI number: 150004355

Start: 2324323

End: 2326311

Strand: Direct

Name: pkn1 [H]

Synonym: BVU_1801

Alternate gene names: 150004355

Gene position: 2324323-2326311 (Clockwise)

Preceding gene: 150004354

Following gene: 150004356

Centisome position: 45.02

GC content: 45.0

Gene sequence:

>1989_bases
ATGAAATTAAAAATTTTAGTAAGTGCAATAGTGAGCATTATTATATGGCCGGCAAGTATTACGGCACAAAGTGAATTGAT
TCCAATGATAGAAATACCCGCAGGAAATTTCTATATGGGAACTTTGGGTGAAGATGAGAATTATGATGAAGCACCTATGC
ATAAGGTGTATATATCCAAACCATTTAAAATGGGGCTGACCGAAGTGACTAATGCGCAATATGAATTGTTCTGCCCTAAA
CACAAGTTGCTGCGTGGTAAAAATGGTTTTTCAAGTGAAGATGACGAAGCGGTGGTGTTCGTAACTTATCAAGATGCCGT
TGCCTTTTGTGACTGGTTGACCCAGAAAGAAGGAAAAACTTATCGTCTGCCTACCGAAGCTGAATGGGAATATGCATGTA
AGGCAGGCCGTTACTGGAATTTCTATATGGATGACAAGCTTCCTGCCGCCTGGCAAAAGAATCAAGTGATAGCGGCTACT
CCCAAACCCTTGTCTTTGAAAGTGGCACAAACTCCTCCTAACGAATGGGGGCTACATGATATGTGTGGAAATGTGGAGGA
ATGGTGTTTGGACTGGTATGGGCCCTATATAGACAAGGAACAGACTGATCCTGTCGGCTATTCGGACGGTATAGCACGGG
TGACTAGAGGAGGTAGTCATAATACACCGATGAAATATCTCCGTTCGGCAAACCGTATGGCTATGTTGCCGGAGGACAAA
CATGCAATGACAGGCTTTCGGGTGGTACAGGCAGAGTATCCGCAGACCGCTCCGCTTTCTCAGCCAAAAGATGAGTATGC
CGTGTCTCAGATAAAATGGGATTGGACTTCTCAGTGTATCACGGAACCTGTCTTCACTGCTCCTTTGGTTTATGTGCATG
AACCGGATGCGCATAGTGGAACGCCTTTTTTCAAGCATAATCATCAGCCGGCATTGACTTGGTGTGATAATGGAGACTTG
TTGGCTGTGTGGTTTTCTACCAATGAAGAAAAAGGCCGTGAGATGGTGGTGCTCTCTTCGCGCTTGCGTGCCGGAAGCCG
TGAATGGGAAAAGCCTCGTATGTTTTATCAGATAGCTGATCGTAATTTGACCGGAACTGCATTGTTGAACGACCGCCAAG
GGACTCTTTACCATATCAATGGAGTGGAAGCGGCCGGACATTGGCAGAATTTGATGATGACTTTGCGTACAAGTACAGAT
AATGGACAAACTTGGAGTAAACCTCGTATGATTGCTCCAGAGCATACGAGACGCCATCAAGTGATAGCCGGAACCTCTAT
TACAAAGGAAGGCTGGTTTGTTCAGGCTTGTGATGCCGGACCCGGTGGAAGAGACGGGGCTGCTGTTCATATCAGTAAGG
ATAAGGGAAAAACTTGGACGGACCCGTGGAATGGAGCGCCCTTGCCCGATTTTAAAGAGGGAGGGACAGGTACCACTATC
GCCGGAATCCATGCCGGAGTGGTGCAATTGAAGGATGGCAGATTGATGGCATTGGGACGTAACAATAGTATTCGTGATAA
AGAAGGACGTCTACGTATGCCTATGAGTGTATCTGATGATATGGGAAAGACTTGGCATTATTCCGCTTCGGAATTTCCAC
CCATTGATGGAGGACAACGGCTGGTATTGATGCGTTTGAATGAAGGTCCTATTTTGCTGATATCTTTTACTGAACATCCT
TATCGTACTCCGAAAGAGGAGCGTGGTATGATGTTTACTGAAAAATCAGGAAAGCCTTTTAAAGGATATGGCATGTACGC
TGCTTTGTCATACGATGAAGGTAAGACCTGGCCTGTAAAACGTTTGTTGACTGATGGCACTTATCGTTTCCTTAATGGTG
GGGCTTGGACTCAGTTTTTTGAAATGGATGAGAATCATGCTGAACCTCGTGGCTACCTGGCCGGAACACAAACACCTGAT
AATATGATTCATTTGATAACGAGCCGCTTTTATTATAAGTTTAATTTAGCTTGGTTGAAAGAAAACTAG

Upstream 100 bases:

>100_bases
GTGTGTTGCTAAATTATGCACATAAAAGACCAATTTTTACCTTATTTTTCTTTGATTGCTTTTTACTTTTGTATCAAGAT
ATATTTTTATCTGATACGAA

Downstream 100 bases:

>100_bases
TATAATAAGGTAAAGAGTATATATGAAAAACATTTTATCTGTTTGCGCATTTTTGCTAGTCTTTGGGATGCTCCCTTTAT
GGGGCAGTTCCAAGATTCTT

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MKLKILVSAIVSIIIWPASITAQSELIPMIEIPAGNFYMGTLGEDENYDEAPMHKVYISKPFKMGLTEVTNAQYELFCPK
HKLLRGKNGFSSEDDEAVVFVTYQDAVAFCDWLTQKEGKTYRLPTEAEWEYACKAGRYWNFYMDDKLPAAWQKNQVIAAT
PKPLSLKVAQTPPNEWGLHDMCGNVEEWCLDWYGPYIDKEQTDPVGYSDGIARVTRGGSHNTPMKYLRSANRMAMLPEDK
HAMTGFRVVQAEYPQTAPLSQPKDEYAVSQIKWDWTSQCITEPVFTAPLVYVHEPDAHSGTPFFKHNHQPALTWCDNGDL
LAVWFSTNEEKGREMVVLSSRLRAGSREWEKPRMFYQIADRNLTGTALLNDRQGTLYHINGVEAAGHWQNLMMTLRTSTD
NGQTWSKPRMIAPEHTRRHQVIAGTSITKEGWFVQACDAGPGGRDGAAVHISKDKGKTWTDPWNGAPLPDFKEGGTGTTI
AGIHAGVVQLKDGRLMALGRNNSIRDKEGRLRMPMSVSDDMGKTWHYSASEFPPIDGGQRLVLMRLNEGPILLISFTEHP
YRTPKEERGMMFTEKSGKPFKGYGMYAALSYDEGKTWPVKRLLTDGTYRFLNGGAWTQFFEMDENHAEPRGYLAGTQTPD
NMIHLITSRFYYKFNLAWLKEN

Sequences:

>Translated_662_residues
MKLKILVSAIVSIIIWPASITAQSELIPMIEIPAGNFYMGTLGEDENYDEAPMHKVYISKPFKMGLTEVTNAQYELFCPK
HKLLRGKNGFSSEDDEAVVFVTYQDAVAFCDWLTQKEGKTYRLPTEAEWEYACKAGRYWNFYMDDKLPAAWQKNQVIAAT
PKPLSLKVAQTPPNEWGLHDMCGNVEEWCLDWYGPYIDKEQTDPVGYSDGIARVTRGGSHNTPMKYLRSANRMAMLPEDK
HAMTGFRVVQAEYPQTAPLSQPKDEYAVSQIKWDWTSQCITEPVFTAPLVYVHEPDAHSGTPFFKHNHQPALTWCDNGDL
LAVWFSTNEEKGREMVVLSSRLRAGSREWEKPRMFYQIADRNLTGTALLNDRQGTLYHINGVEAAGHWQNLMMTLRTSTD
NGQTWSKPRMIAPEHTRRHQVIAGTSITKEGWFVQACDAGPGGRDGAAVHISKDKGKTWTDPWNGAPLPDFKEGGTGTTI
AGIHAGVVQLKDGRLMALGRNNSIRDKEGRLRMPMSVSDDMGKTWHYSASEFPPIDGGQRLVLMRLNEGPILLISFTEHP
YRTPKEERGMMFTEKSGKPFKGYGMYAALSYDEGKTWPVKRLLTDGTYRFLNGGAWTQFFEMDENHAEPRGYLAGTQTPD
NMIHLITSRFYYKFNLAWLKEN
>Mature_662_residues
MKLKILVSAIVSIIIWPASITAQSELIPMIEIPAGNFYMGTLGEDENYDEAPMHKVYISKPFKMGLTEVTNAQYELFCPK
HKLLRGKNGFSSEDDEAVVFVTYQDAVAFCDWLTQKEGKTYRLPTEAEWEYACKAGRYWNFYMDDKLPAAWQKNQVIAAT
PKPLSLKVAQTPPNEWGLHDMCGNVEEWCLDWYGPYIDKEQTDPVGYSDGIARVTRGGSHNTPMKYLRSANRMAMLPEDK
HAMTGFRVVQAEYPQTAPLSQPKDEYAVSQIKWDWTSQCITEPVFTAPLVYVHEPDAHSGTPFFKHNHQPALTWCDNGDL
LAVWFSTNEEKGREMVVLSSRLRAGSREWEKPRMFYQIADRNLTGTALLNDRQGTLYHINGVEAAGHWQNLMMTLRTSTD
NGQTWSKPRMIAPEHTRRHQVIAGTSITKEGWFVQACDAGPGGRDGAAVHISKDKGKTWTDPWNGAPLPDFKEGGTGTTI
AGIHAGVVQLKDGRLMALGRNNSIRDKEGRLRMPMSVSDDMGKTWHYSASEFPPIDGGQRLVLMRLNEGPILLISFTEHP
YRTPKEERGMMFTEKSGKPFKGYGMYAALSYDEGKTWPVKRLLTDGTYRFLNGGAWTQFFEMDENHAEPRGYLAGTQTPD
NMIHLITSRFYYKFNLAWLKEN

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=263, Percent_Identity=31.5589353612167, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI38202250, Length=288, Percent_Identity=28.8194444444444, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI257470977, Length=284, Percent_Identity=26.056338028169, Blast_Score=70, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 75026; Mature: 75026

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKILVSAIVSIIIWPASITAQSELIPMIEIPAGNFYMGTLGEDENYDEAPMHKVYISK
CEEEHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECC
PFKMGLTEVTNAQYELFCPKHKLLRGKNGFSSEDDEAVVFVTYQDAVAFCDWLTQKEGKT
CHHCCCHHHCCCEEEEECCHHHHHCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCE
YRLPTEAEWEYACKAGRYWNFYMDDKLPAAWQKNQVIAATPKPLSLKVAQTPPNEWGLHD
EECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCHHH
MCGNVEEWCLDWYGPYIDKEQTDPVGYSDGIARVTRGGSHNTPMKYLRSANRMAMLPEDK
HHCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHCCCCEEECCCCC
HAMTGFRVVQAEYPQTAPLSQPKDEYAVSQIKWDWTSQCITEPVFTAPLVYVHEPDAHSG
HHCCCEEEEEECCCCCCCCCCCCHHHHHHEEEECHHHHHHCCCCHHCCEEEEECCCCCCC
TPFFKHNHQPALTWCDNGDLLAVWFSTNEEKGREMVVLSSRLRAGSREWEKPRMFYQIAD
CCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEEEEEHHHCCCCCCCCCCEEEEEEEC
RNLTGTALLNDRQGTLYHINGVEAAGHWQNLMMTLRTSTDNGQTWSKPRMIAPEHTRRHQ
CCCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCE
VIAGTSITKEGWFVQACDAGPGGRDGAAVHISKDKGKTWTDPWNGAPLPDFKEGGTGTTI
EEECCEEECCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEE
AGIHAGVVQLKDGRLMALGRNNSIRDKEGRLRMPMSVSDDMGKTWHYSASEFPPIDGGQR
EEEEECEEEECCCEEEEECCCCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCE
LVLMRLNEGPILLISFTEHPYRTPKEERGMMFTEKSGKPFKGYGMYAALSYDEGKTWPVK
EEEEEECCCCEEEEEECCCCCCCCHHHCCEEEEECCCCCCCCCCEEEEEEECCCCCCHHH
RLLTDGTYRFLNGGAWTQFFEMDENHAEPRGYLAGTQTPDNMIHLITSRFYYKFNLAWLK
HHHCCCCEEEECCCCEEEEEECCCCCCCCCCEEECCCCCHHHHHHEECCEEEEEEEEEEE
EN
CC
>Mature Secondary Structure
MKLKILVSAIVSIIIWPASITAQSELIPMIEIPAGNFYMGTLGEDENYDEAPMHKVYISK
CEEEHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECC
PFKMGLTEVTNAQYELFCPKHKLLRGKNGFSSEDDEAVVFVTYQDAVAFCDWLTQKEGKT
CHHCCCHHHCCCEEEEECCHHHHHCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCE
YRLPTEAEWEYACKAGRYWNFYMDDKLPAAWQKNQVIAATPKPLSLKVAQTPPNEWGLHD
EECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCHHH
MCGNVEEWCLDWYGPYIDKEQTDPVGYSDGIARVTRGGSHNTPMKYLRSANRMAMLPEDK
HHCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHCCCCEEECCCCC
HAMTGFRVVQAEYPQTAPLSQPKDEYAVSQIKWDWTSQCITEPVFTAPLVYVHEPDAHSG
HHCCCEEEEEECCCCCCCCCCCCHHHHHHEEEECHHHHHHCCCCHHCCEEEEECCCCCCC
TPFFKHNHQPALTWCDNGDLLAVWFSTNEEKGREMVVLSSRLRAGSREWEKPRMFYQIAD
CCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEEEEEHHHCCCCCCCCCCEEEEEEEC
RNLTGTALLNDRQGTLYHINGVEAAGHWQNLMMTLRTSTDNGQTWSKPRMIAPEHTRRHQ
CCCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCE
VIAGTSITKEGWFVQACDAGPGGRDGAAVHISKDKGKTWTDPWNGAPLPDFKEGGTGTTI
EEECCEEECCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEE
AGIHAGVVQLKDGRLMALGRNNSIRDKEGRLRMPMSVSDDMGKTWHYSASEFPPIDGGQR
EEEEECEEEECCCEEEEECCCCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCE
LVLMRLNEGPILLISFTEHPYRTPKEERGMMFTEKSGKPFKGYGMYAALSYDEGKTWPVK
EEEEEECCCCEEEEEECCCCCCCCHHHCCEEEEECCCCCCCCCCEEEEEEECCCCCCHHH
RLLTDGTYRFLNGGAWTQFFEMDENHAEPRGYLAGTQTPDNMIHLITSRFYYKFNLAWLK
HHHCCCCEEEECCCCEEEEEECCCCCCCCCCEEECCCCCHHHHHHEECCEEEEEEEEEEE
EN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]