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The map label for this gene is lacZ [H]

Identifier: 150004339

GI number: 150004339

Start: 2295065

End: 2297635

Strand: Direct

Name: lacZ [H]

Synonym: BVU_1785

Alternate gene names: 150004339

Gene position: 2295065-2297635 (Clockwise)

Preceding gene: 150004338

Following gene: 150004340

Centisome position: 44.45

GC content: 37.03

Gene sequence:

>2571_bases
ATGCAGTATAAAGTATTATTCAAGAGATGCTTGTTGGCTATAGTGGTAATGTTTGTCGTTACCTCTTTACAAGCGCAGCG
GGAAATGAAGACTATCAATGATAATTGGGAATTTCGGAAATCTATAGATGAATCATGGGAATCTGTCAATCTCCCCCATA
CTTTTAATATAGATGCTTATCAACAACGAAATTATTATCAAGGTAAGGGATTCTACAGGCGTACTCTCGTTTTACCGGAA
ATTGTTGCGGAACGTCGTTATTATATGAAAATAGATGCTGCTAGTAAGGCTGCTAATATTAGAGTGAATGGAAAGGAAGT
AGGCAGTCATGTAGGTGGTTATACAGCTTGTATTGTAGATATAACAGAGTATATCAGAAAAGAGAATTTGATAGAGATTA
CGGTTGACAATGGGAGAAAAGATATTACTCCTATATCGGCAGATTTCACTTTTTGGGGGGGGATCTACAGAGATGTATGG
CTCATATCTACTCCAAAACAACACTTCAATATGAGCAATATGGGATCTGATGGAATTTTTATTAGTACTCCAGTAGTGAA
TGAAAAAAGAGGAGTATTGAAAGTAAAATGTGAAGTGACTAATGATTCTCATGAAAGTTCTATATTGGAAGTCAGAAGTG
CAATTTATAGTCCGCAAGGAAAACTTTTGCAGACTATTAAACAAAAACAAAAACTTAAGAGTGGCGAAACCTATATTTTT
GAAAACACATCTGGTGCTATTGAGAGTCCTGATTTGTGGAGTCCAGAAACTCCTTCACTTTATTTGGTAAAAACTACCTT
GGTAGATCCGAAGTCAGGAAAGCTATTGGATGAAAAAAATCATAAGGTGGGATTTCGCTGGTTTACCTTTGATGGAAGTA
AAGGTTTTTTCCTTAATGGAAAATCTTATAAATTACGTGGACTCAATCGTCATCAAGATCAAGCTCCGGCAGGGGTAGCT
TTAGATGACGAAGCCCATCGACGAGACATATTTTTAATGAAAGAGTTGGGATGTAACTTTATTCGTATTTCACATTTTCC
ACAAGATGATGCAATATTGGAAATGTGTGACGAATTGGGACTATTGGCATGGGAGGAAATTCCTATCATTAATATTGTAC
CGAATACACCTGGATATGATGATAATTGTGAATATAATCTGCGTGAGATGATTCGCCAGCATTATAATCATTCATCTGTT
ATAACATGGGGATATATGAACGAAATTCTTCTTACTGCTCCTTCCATTGGTAAACCTGAGTGGCTAGCATGTAAAGAGCG
CACGGTAAATCTAGCACAACGACTGGAAGCCGTTCTGAAAGAAGAAGATCCAGGAAGAGCCAGTGTTATGGCATTTAATA
TGACCAATCTATACAATGAAATAGGTTTGAATCTAGTAGACGTAGTAGGTTGGAATTTATATCATGGTTGGTATGTTGAT
AAATTAAAAGATTTTAATGCATGGTGTGAAGATCAACATCGTCGTTACCCTGACCAACCTATGATTATCAGTGAATGGGG
AGCAGGCAGTGACAAGCGGCTGCATTCCACTCAAGGACGTGCCTTTGATTTTAGTATCGAATATCAACAAACGTATATAG
AACATTATCTTCCTTTTATAGAGAATACAGAATGGATTAGTGGATGCGCTTATTGGAATTTCATTGATTTTAATGTGGCT
GCTCGCCAGGAGTCAATGCCTAGAGTAAACAATAAGGGATTGGCTTATAATAACCGTATATGGAAGGATGTGGCTTACTA
TTTTAAGGCTATGTGGCGGAAAGATATTCCAGTAATAAGAATTGCCAGCCGTGATTGGGAAATGCGTACTGGGGAAATAA
ATAAGCCACAGTCCATTAAAATTTATTCAAATATGCCGGAAGTGGAATTGTTTATTAACGGACAATCAATAGGATGTCAA
AAGATAGCTAATTGTCACACTGTCTTTAATGTAATTTTACCGGAAGGTATATCAGTTCTTATGGCGCAAGGAATCAAAAA
TGGGAAAACAGTTCAAGATGCTATGACAATTCAGTTCAAGTCACTTCCTAATATAGCTGAAGGAGATGAATTGGCAATTA
ATGTAGGAAGTAATTGTTACTTTACGTCAGATATCAGTAATCTTACTTGGTTACCTGATCAACCTTATACTGCGGGAGGT
TGGGGATATATAGGTGGAAAAGCGCATAGCACTACCTCTGAAATTTATAATACTTTAGATGGGCCAATATACCAGACGTG
GCGTGAAGGAAACTGGAGTTATAAAATCGATGCTCCTATAGGAGAGTATGAAATAGAACTGCTTATAGCAGATGTTACTA
AACCTGCTGCTCAGTTGGCCAATCTTTTAAATAAGAATAAAGAAGAAAAGCATTCGGGAGAAACACGTTTTCATATTTCC
ATTTGTGGAAAACAAGTAGAAACTAATTTTTCTCCAATTGATGGAGGAAAGCATCGTACTGCCTTTAAGCGTCGCTATAT
TATTCGAAACGAACATGATCATATTGTTATTAGTGCAGGGGCAGTGAAAGGAGAACCGTTTTTAGCTGGTATTAAGGTAC
GGAAACTTTGA

Upstream 100 bases:

>100_bases
AATCTTGGACTTCCAAAAAGGCTTGGGAAGGAGAAGAATTTCCTAAAGATCATACATATTATGAAAAACACTCAATGAAT
TACCAGTAAAAAAATAATGT

Downstream 100 bases:

>100_bases
TATGTGACAAAAGAGTCTTAAAAAGAAAGAATTTGTCTCAAAACACTTTTGATACGGATTCTTTCTTTTTAAATAGTGCA
ATTTATTGTCCGTACTGTAC

Product: beta-glycosidase

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 856; Mature: 856

Protein sequence:

>856_residues
MQYKVLFKRCLLAIVVMFVVTSLQAQREMKTINDNWEFRKSIDESWESVNLPHTFNIDAYQQRNYYQGKGFYRRTLVLPE
IVAERRYYMKIDAASKAANIRVNGKEVGSHVGGYTACIVDITEYIRKENLIEITVDNGRKDITPISADFTFWGGIYRDVW
LISTPKQHFNMSNMGSDGIFISTPVVNEKRGVLKVKCEVTNDSHESSILEVRSAIYSPQGKLLQTIKQKQKLKSGETYIF
ENTSGAIESPDLWSPETPSLYLVKTTLVDPKSGKLLDEKNHKVGFRWFTFDGSKGFFLNGKSYKLRGLNRHQDQAPAGVA
LDDEAHRRDIFLMKELGCNFIRISHFPQDDAILEMCDELGLLAWEEIPIINIVPNTPGYDDNCEYNLREMIRQHYNHSSV
ITWGYMNEILLTAPSIGKPEWLACKERTVNLAQRLEAVLKEEDPGRASVMAFNMTNLYNEIGLNLVDVVGWNLYHGWYVD
KLKDFNAWCEDQHRRYPDQPMIISEWGAGSDKRLHSTQGRAFDFSIEYQQTYIEHYLPFIENTEWISGCAYWNFIDFNVA
ARQESMPRVNNKGLAYNNRIWKDVAYYFKAMWRKDIPVIRIASRDWEMRTGEINKPQSIKIYSNMPEVELFINGQSIGCQ
KIANCHTVFNVILPEGISVLMAQGIKNGKTVQDAMTIQFKSLPNIAEGDELAINVGSNCYFTSDISNLTWLPDQPYTAGG
WGYIGGKAHSTTSEIYNTLDGPIYQTWREGNWSYKIDAPIGEYEIELLIADVTKPAAQLANLLNKNKEEKHSGETRFHIS
ICGKQVETNFSPIDGGKHRTAFKRRYIIRNEHDHIVISAGAVKGEPFLAGIKVRKL

Sequences:

>Translated_856_residues
MQYKVLFKRCLLAIVVMFVVTSLQAQREMKTINDNWEFRKSIDESWESVNLPHTFNIDAYQQRNYYQGKGFYRRTLVLPE
IVAERRYYMKIDAASKAANIRVNGKEVGSHVGGYTACIVDITEYIRKENLIEITVDNGRKDITPISADFTFWGGIYRDVW
LISTPKQHFNMSNMGSDGIFISTPVVNEKRGVLKVKCEVTNDSHESSILEVRSAIYSPQGKLLQTIKQKQKLKSGETYIF
ENTSGAIESPDLWSPETPSLYLVKTTLVDPKSGKLLDEKNHKVGFRWFTFDGSKGFFLNGKSYKLRGLNRHQDQAPAGVA
LDDEAHRRDIFLMKELGCNFIRISHFPQDDAILEMCDELGLLAWEEIPIINIVPNTPGYDDNCEYNLREMIRQHYNHSSV
ITWGYMNEILLTAPSIGKPEWLACKERTVNLAQRLEAVLKEEDPGRASVMAFNMTNLYNEIGLNLVDVVGWNLYHGWYVD
KLKDFNAWCEDQHRRYPDQPMIISEWGAGSDKRLHSTQGRAFDFSIEYQQTYIEHYLPFIENTEWISGCAYWNFIDFNVA
ARQESMPRVNNKGLAYNNRIWKDVAYYFKAMWRKDIPVIRIASRDWEMRTGEINKPQSIKIYSNMPEVELFINGQSIGCQ
KIANCHTVFNVILPEGISVLMAQGIKNGKTVQDAMTIQFKSLPNIAEGDELAINVGSNCYFTSDISNLTWLPDQPYTAGG
WGYIGGKAHSTTSEIYNTLDGPIYQTWREGNWSYKIDAPIGEYEIELLIADVTKPAAQLANLLNKNKEEKHSGETRFHIS
ICGKQVETNFSPIDGGKHRTAFKRRYIIRNEHDHIVISAGAVKGEPFLAGIKVRKL
>Mature_856_residues
MQYKVLFKRCLLAIVVMFVVTSLQAQREMKTINDNWEFRKSIDESWESVNLPHTFNIDAYQQRNYYQGKGFYRRTLVLPE
IVAERRYYMKIDAASKAANIRVNGKEVGSHVGGYTACIVDITEYIRKENLIEITVDNGRKDITPISADFTFWGGIYRDVW
LISTPKQHFNMSNMGSDGIFISTPVVNEKRGVLKVKCEVTNDSHESSILEVRSAIYSPQGKLLQTIKQKQKLKSGETYIF
ENTSGAIESPDLWSPETPSLYLVKTTLVDPKSGKLLDEKNHKVGFRWFTFDGSKGFFLNGKSYKLRGLNRHQDQAPAGVA
LDDEAHRRDIFLMKELGCNFIRISHFPQDDAILEMCDELGLLAWEEIPIINIVPNTPGYDDNCEYNLREMIRQHYNHSSV
ITWGYMNEILLTAPSIGKPEWLACKERTVNLAQRLEAVLKEEDPGRASVMAFNMTNLYNEIGLNLVDVVGWNLYHGWYVD
KLKDFNAWCEDQHRRYPDQPMIISEWGAGSDKRLHSTQGRAFDFSIEYQQTYIEHYLPFIENTEWISGCAYWNFIDFNVA
ARQESMPRVNNKGLAYNNRIWKDVAYYFKAMWRKDIPVIRIASRDWEMRTGEINKPQSIKIYSNMPEVELFINGQSIGCQ
KIANCHTVFNVILPEGISVLMAQGIKNGKTVQDAMTIQFKSLPNIAEGDELAINVGSNCYFTSDISNLTWLPDQPYTAGG
WGYIGGKAHSTTSEIYNTLDGPIYQTWREGNWSYKIDAPIGEYEIELLIADVTKPAAQLANLLNKNKEEKHSGETRFHIS
ICGKQVETNFSPIDGGKHRTAFKRRYIIRNEHDHIVISAGAVKGEPFLAGIKVRKL

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=662, Percent_Identity=24.773413897281, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1787903, Length=635, Percent_Identity=26.2992125984252, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI48994920, Length=353, Percent_Identity=24.6458923512748, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1786539, Length=440, Percent_Identity=22.0454545454545, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17510825, Length=575, Percent_Identity=23.8260869565217, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI62471735, Length=608, Percent_Identity=24.8355263157895, Blast_Score=143, Evalue=6e-34,
Organism=Drosophila melanogaster, GI19922582, Length=608, Percent_Identity=24.8355263157895, Blast_Score=143, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24655438, Length=630, Percent_Identity=24.4444444444444, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24651745, Length=621, Percent_Identity=24.3156199677939, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 98045; Mature: 98045

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYKVLFKRCLLAIVVMFVVTSLQAQREMKTINDNWEFRKSIDESWESVNLPHTFNIDAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCH
QQRNYYQGKGFYRRTLVLPEIVAERRYYMKIDAASKAANIRVNGKEVGSHVGGYTACIVD
HCCCCCCCCCEEEEEEHHHHHHHCCEEEEEEECCCCCEEEEECHHHHHCCCCCHHHHHHH
ITEYIRKENLIEITVDNGRKDITPISADFTFWGGIYRDVWLISTPKQHFNMSNMGSDGIF
HHHHHHHCCEEEEEECCCCCCCCEEECCCEECCCHHHEEEEEECCHHHCCCCCCCCCCEE
ISTPVVNEKRGVLKVKCEVTNDSHESSILEVRSAIYSPQGKLLQTIKQKQKLKSGETYIF
EECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEE
ENTSGAIESPDLWSPETPSLYLVKTTLVDPKSGKLLDEKNHKVGFRWFTFDGSKGFFLNG
ECCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCEEEECC
KSYKLRGLNRHQDQAPAGVALDDEAHRRDIFLMKELGCNFIRISHFPQDDAILEMCDELG
CCEEEECCCCCCCCCCCCEEECCCCCHHHEEEEHHHCCCEEEEECCCCCHHHHHHHHHCC
LLAWEEIPIINIVPNTPGYDDNCEYNLREMIRQHYNHSSVITWGYMNEILLTAPSIGKPE
CEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCC
WLACKERTVNLAQRLEAVLKEEDPGRASVMAFNMTNLYNEIGLNLVDVVGWNLYHGWYVD
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHCCEEEEHHCCCEECCEEHH
KLKDFNAWCEDQHRRYPDQPMIISEWGAGSDKRLHSTQGRAFDFSIEYQQTYIEHYLPFI
HHHHCCHHHHHHHCCCCCCCEEEEECCCCCCCCEECCCCCEEEEEEHHHHHHHHHHHHHH
ENTEWISGCAYWNFIDFNVAARQESMPRVNNKGLAYNNRIWKDVAYYFKAMWRKDIPVIR
CCCCHHCCEEEEEEEEEEEEHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCEEE
IASRDWEMRTGEINKPQSIKIYSNMPEVELFINGQSIGCQKIANCHTVFNVILPEGISVL
EECCCCEECCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHH
MAQGIKNGKTVQDAMTIQFKSLPNIAEGDELAINVGSNCYFTSDISNLTWLPDQPYTAGG
HHHCCCCCCEEHHEEEEEECCCCCCCCCCEEEEEECCCEEEECCCCCCEECCCCCCCCCC
WGYIGGKAHSTTSEIYNTLDGPIYQTWREGNWSYKIDAPIGEYEIELLIADVTKPAAQLA
CCCCCCCCCCCHHHHHHHCCCCHHHHHHCCCEEEEECCCCCCEEEEEEEEECCHHHHHHH
NLLNKNKEEKHSGETRFHISICGKQVETNFSPIDGGKHRTAFKRRYIIRNEHDHIVISAG
HHHCCCCCHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEEEEC
AVKGEPFLAGIKVRKL
CCCCCCEEECEEEECC
>Mature Secondary Structure
MQYKVLFKRCLLAIVVMFVVTSLQAQREMKTINDNWEFRKSIDESWESVNLPHTFNIDAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCH
QQRNYYQGKGFYRRTLVLPEIVAERRYYMKIDAASKAANIRVNGKEVGSHVGGYTACIVD
HCCCCCCCCCEEEEEEHHHHHHHCCEEEEEEECCCCCEEEEECHHHHHCCCCCHHHHHHH
ITEYIRKENLIEITVDNGRKDITPISADFTFWGGIYRDVWLISTPKQHFNMSNMGSDGIF
HHHHHHHCCEEEEEECCCCCCCCEEECCCEECCCHHHEEEEEECCHHHCCCCCCCCCCEE
ISTPVVNEKRGVLKVKCEVTNDSHESSILEVRSAIYSPQGKLLQTIKQKQKLKSGETYIF
EECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEE
ENTSGAIESPDLWSPETPSLYLVKTTLVDPKSGKLLDEKNHKVGFRWFTFDGSKGFFLNG
ECCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCEEEECC
KSYKLRGLNRHQDQAPAGVALDDEAHRRDIFLMKELGCNFIRISHFPQDDAILEMCDELG
CCEEEECCCCCCCCCCCCEEECCCCCHHHEEEEHHHCCCEEEEECCCCCHHHHHHHHHCC
LLAWEEIPIINIVPNTPGYDDNCEYNLREMIRQHYNHSSVITWGYMNEILLTAPSIGKPE
CEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCC
WLACKERTVNLAQRLEAVLKEEDPGRASVMAFNMTNLYNEIGLNLVDVVGWNLYHGWYVD
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHCCEEEEHHCCCEECCEEHH
KLKDFNAWCEDQHRRYPDQPMIISEWGAGSDKRLHSTQGRAFDFSIEYQQTYIEHYLPFI
HHHHCCHHHHHHHCCCCCCCEEEEECCCCCCCCEECCCCCEEEEEEHHHHHHHHHHHHHH
ENTEWISGCAYWNFIDFNVAARQESMPRVNNKGLAYNNRIWKDVAYYFKAMWRKDIPVIR
CCCCHHCCEEEEEEEEEEEEHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCEEE
IASRDWEMRTGEINKPQSIKIYSNMPEVELFINGQSIGCQKIANCHTVFNVILPEGISVL
EECCCCEECCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHH
MAQGIKNGKTVQDAMTIQFKSLPNIAEGDELAINVGSNCYFTSDISNLTWLPDQPYTAGG
HHHCCCCCCEEHHEEEEEECCCCCCCCCCEEEEEECCCEEEECCCCCCEECCCCCCCCCC
WGYIGGKAHSTTSEIYNTLDGPIYQTWREGNWSYKIDAPIGEYEIELLIADVTKPAAQLA
CCCCCCCCCCCHHHHHHHCCCCHHHHHHCCCEEEEECCCCCCEEEEEEEEECCHHHHHHH
NLLNKNKEEKHSGETRFHISICGKQVETNFSPIDGGKHRTAFKRRYIIRNEHDHIVISAG
HHHCCCCCHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEEEEC
AVKGEPFLAGIKVRKL
CCCCCCEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA