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The map label for this gene is yidJ [C]

Identifier: 150004325

GI number: 150004325

Start: 2273550

End: 2274983

Strand: Reverse

Name: yidJ [C]

Synonym: BVU_1771

Alternate gene names: 150004325

Gene position: 2274983-2273550 (Counterclockwise)

Preceding gene: 150004326

Following gene: 150004323

Centisome position: 44.06

GC content: 38.91

Gene sequence:

>1434_bases
ATGCAGTTAAAATACACTTTGTTTTCAAGCATTTCAATGCTTGCCTTCTCTTCTCTGTCTGTATTTTCACAGACAGAGAA
AATGAACGTTCTATTCTTGATGGCAGACGATATGCGCCCTGAGTTAGGATGCTATGGGGTAAAAGAAGTAAAGACCCCCA
ATATTGACCGTTTTGCCGCCAGCGGGTTATTATTTCAGAACGCTTACTGCAATATCCCAGTAAGTGGAGCTTCACGCGCC
AGCTTATTAACAGGAGTGTATCCACACTATCCAGATCGTTTTGTCAACTATTCCGCTTATGCCAGCAAAGATTGCCCGAC
CGCAATTCCGATATCAAGATGGTTTACATCACATGGCTATTACACAATCTCAAACGGCAAGGTTTTCCACCATCTTTCAG
ATCATGCTAATTCATGGAGTGAACCCCCTTACCGTAAACATCCCGACGGATATGATGTATATTGGGCAGAATACAATAAA
TGGGAATTATGGATGAATGAAGCCTCCGCACGAACTATCAATCCCAAAACAATGCGTGGACCTTTCTGTGAGTGGGCTGA
AGTACCTGACACCGCTTATGATGACGGAAAACTGGCATTAAAAGCCATTGCAGACTTAAAACGTTTAAAAGAACAAGGAA
AACCTTTCTTTATGGCATGTGGATTTTGGAAGCCACATTTACCTTTTAATGCCCCTAAAAAATATTGGGATTTATATGAC
CGAGAGAAAATTCCAGTTGCTAACAATCGTTTTCGTCCTAAAGATCTACCGAATGAGGTTAAAAACTCTACAGAAATCTA
CGCTTACGCACGTACCACCACAGCAGATGATATTTCTTTTCAGAAAGAAGCCAAACATGGATATTATGCTTGTCTGAGTT
ATGTTGATGCGCAAATAGGGAAAGTACTGGACGCTCTGGATGAGTTAGGTTTAGCAAATAATACCATCGTTGTATTACTG
GGAGACCATGGCTGGCATCTAGGGGAACATAACTTTCTCGGTAAGCATAATTTAATGGATCGTTCTACTCACGTTCCTTT
AATTGTACGTGTTCCCGGATTGAAAAAAGGAAAGACTAAGTCCATGGTAGAATTCGTAGATTTATATCCGACACTATGTG
AACTTTGTCATTTGCCCATACCAAAGAATCAATTAGATGGCACTAGTTTTGTTCCTATTTTAACAAATTTAAAAGCAAAA
ATAAAAGACCAAGTATATATCCAATGGGAAGGAGGGGACAATACTGTTAGCAATAGATACAACTATGCGGAATGGAAACA
AAAAGAAAAGATTCATTCTCGAATGTTGTTTGACCATCACATAGATCCAGAAGAAAATAAGAACAGGGTCAACGAACGAA
AGTATAGAAGCGAAATTAATAAGCTCTCTTCATTTTTAAAGGCTAAAAAAGAAACTTTAATGAAATCACAATGA

Upstream 100 bases:

>100_bases
TGGTTGGAACATTACTATCTAAATCCAATTCCTCTAAATCAATTGGCACTCAATCCTGCTCTCGAACAAAATCCTGGATG
GGAAAACAATAAATAAAATT

Downstream 100 bases:

>100_bases
AAAAACTTTCCGGTTTACCTGCTCTAACCATCGAGATCGGATTATAACTGAAAGCCATTTGACGATTGTTTTTTGTAAAA
TAAGAAGTGATAGGCATATT

Product: iduronate 2-sulfatase precursor

Products: NA

Alternate protein names: Cys-type sulfatase [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MQLKYTLFSSISMLAFSSLSVFSQTEKMNVLFLMADDMRPELGCYGVKEVKTPNIDRFAASGLLFQNAYCNIPVSGASRA
SLLTGVYPHYPDRFVNYSAYASKDCPTAIPISRWFTSHGYYTISNGKVFHHLSDHANSWSEPPYRKHPDGYDVYWAEYNK
WELWMNEASARTINPKTMRGPFCEWAEVPDTAYDDGKLALKAIADLKRLKEQGKPFFMACGFWKPHLPFNAPKKYWDLYD
REKIPVANNRFRPKDLPNEVKNSTEIYAYARTTTADDISFQKEAKHGYYACLSYVDAQIGKVLDALDELGLANNTIVVLL
GDHGWHLGEHNFLGKHNLMDRSTHVPLIVRVPGLKKGKTKSMVEFVDLYPTLCELCHLPIPKNQLDGTSFVPILTNLKAK
IKDQVYIQWEGGDNTVSNRYNYAEWKQKEKIHSRMLFDHHIDPEENKNRVNERKYRSEINKLSSFLKAKKETLMKSQ

Sequences:

>Translated_477_residues
MQLKYTLFSSISMLAFSSLSVFSQTEKMNVLFLMADDMRPELGCYGVKEVKTPNIDRFAASGLLFQNAYCNIPVSGASRA
SLLTGVYPHYPDRFVNYSAYASKDCPTAIPISRWFTSHGYYTISNGKVFHHLSDHANSWSEPPYRKHPDGYDVYWAEYNK
WELWMNEASARTINPKTMRGPFCEWAEVPDTAYDDGKLALKAIADLKRLKEQGKPFFMACGFWKPHLPFNAPKKYWDLYD
REKIPVANNRFRPKDLPNEVKNSTEIYAYARTTTADDISFQKEAKHGYYACLSYVDAQIGKVLDALDELGLANNTIVVLL
GDHGWHLGEHNFLGKHNLMDRSTHVPLIVRVPGLKKGKTKSMVEFVDLYPTLCELCHLPIPKNQLDGTSFVPILTNLKAK
IKDQVYIQWEGGDNTVSNRYNYAEWKQKEKIHSRMLFDHHIDPEENKNRVNERKYRSEINKLSSFLKAKKETLMKSQ
>Mature_477_residues
MQLKYTLFSSISMLAFSSLSVFSQTEKMNVLFLMADDMRPELGCYGVKEVKTPNIDRFAASGLLFQNAYCNIPVSGASRA
SLLTGVYPHYPDRFVNYSAYASKDCPTAIPISRWFTSHGYYTISNGKVFHHLSDHANSWSEPPYRKHPDGYDVYWAEYNK
WELWMNEASARTINPKTMRGPFCEWAEVPDTAYDDGKLALKAIADLKRLKEQGKPFFMACGFWKPHLPFNAPKKYWDLYD
REKIPVANNRFRPKDLPNEVKNSTEIYAYARTTTADDISFQKEAKHGYYACLSYVDAQIGKVLDALDELGLANNTIVVLL
GDHGWHLGEHNFLGKHNLMDRSTHVPLIVRVPGLKKGKTKSMVEFVDLYPTLCELCHLPIPKNQLDGTSFVPILTNLKAK
IKDQVYIQWEGGDNTVSNRYNYAEWKQKEKIHSRMLFDHHIDPEENKNRVNERKYRSEINKLSSFLKAKKETLMKSQ

Specific function: Has sulfatase activity toward para-nitrophenyl sulfate, which is increased in presence of calcium ion [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4557659, Length=426, Percent_Identity=34.5070422535211, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI5360208, Length=344, Percent_Identity=35.1744186046512, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI262118210, Length=322, Percent_Identity=33.2298136645963, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI39930577, Length=385, Percent_Identity=26.7532467532467, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI4504061, Length=416, Percent_Identity=27.1634615384615, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1790112, Length=364, Percent_Identity=28.8461538461538, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87081924, Length=373, Percent_Identity=25.4691689008043, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24656835, Length=398, Percent_Identity=29.8994974874372, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24647401, Length=416, Percent_Identity=25.7211538461538, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 54890; Mature: 54890

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKYTLFSSISMLAFSSLSVFSQTEKMNVLFLMADDMRPELGCYGVKEVKTPNIDRFAA
CCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHCCCCCHHHHHH
SGLLFQNAYCNIPVSGASRASLLTGVYPHYPDRFVNYSAYASKDCPTAIPISRWFTSHGY
CCEEEECCEECCCCCCCCHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHCCCE
YTISNGKVFHHLSDHANSWSEPPYRKHPDGYDVYWAEYNKWELWMNEASARTINPKTMRG
EEECCCEEEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCC
PFCEWAEVPDTAYDDGKLALKAIADLKRLKEQGKPFFMACGFWKPHLPFNAPKKYWDLYD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHCCC
REKIPVANNRFRPKDLPNEVKNSTEIYAYARTTTADDISFQKEAKHGYYACLSYVDAQIG
CCCCCCCCCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHHH
KVLDALDELGLANNTIVVLLGDHGWHLGEHNFLGKHNLMDRSTHVPLIVRVPGLKKGKTK
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHH
SMVEFVDLYPTLCELCHLPIPKNQLDGTSFVPILTNLKAKIKDQVYIQWEGGDNTVSNRY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHCCHHEECCEEEEEEECCCCCHHCCC
NYAEWKQKEKIHSRMLFDHHIDPEENKNRVNERKYRSEINKLSSFLKAKKETLMKSQ
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLKYTLFSSISMLAFSSLSVFSQTEKMNVLFLMADDMRPELGCYGVKEVKTPNIDRFAA
CCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHCCCCCHHHHHH
SGLLFQNAYCNIPVSGASRASLLTGVYPHYPDRFVNYSAYASKDCPTAIPISRWFTSHGY
CCEEEECCEECCCCCCCCHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHCCCE
YTISNGKVFHHLSDHANSWSEPPYRKHPDGYDVYWAEYNKWELWMNEASARTINPKTMRG
EEECCCEEEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCC
PFCEWAEVPDTAYDDGKLALKAIADLKRLKEQGKPFFMACGFWKPHLPFNAPKKYWDLYD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHCCC
REKIPVANNRFRPKDLPNEVKNSTEIYAYARTTTADDISFQKEAKHGYYACLSYVDAQIG
CCCCCCCCCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHHH
KVLDALDELGLANNTIVVLLGDHGWHLGEHNFLGKHNLMDRSTHVPLIVRVPGLKKGKTK
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHH
SMVEFVDLYPTLCELCHLPIPKNQLDGTSFVPILTNLKAKIKDQVYIQWEGGDNTVSNRY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHCCHHEECCEEEEEEECCCCCHHCCC
NYAEWKQKEKIHSRMLFDHHIDPEENKNRVNERKYRSEINKLSSFLKAKKETLMKSQ
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA