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The map label for this gene is alr1 [H]

Identifier: 150004319

GI number: 150004319

Start: 2262873

End: 2265338

Strand: Direct

Name: alr1 [H]

Synonym: BVU_1765

Alternate gene names: 150004319

Gene position: 2262873-2265338 (Clockwise)

Preceding gene: 150004318

Following gene: 150004320

Centisome position: 43.83

GC content: 42.82

Gene sequence:

>2466_bases
ATGTCAAGCTCGATTGAAAATATAGAAAAAGTTCTGGGAGCAAAGCGGTTTGGGGACCGTAGTGCACAGATTGATTGGAT
TTTAACTGATAGCCGTTCATTGTGCTTTCCGGAAGAAACATTATTTTTTGCTTTAAAAACCAAACGGAATGACGGGCATA
AATATCTTCCGGAATTGTATGAACGTGGAGTCCGTAATTTTGTAGTGGGCGAATTGCCGGCCGATATGAAATCTTTTCAA
GATGCGAATTTCCTGCAGTTGGCCAATCCTCTGAAAGGATTACAGAAATTGGCGGAAAAGCATCGGGAGCAGTTTCAGAT
TCCGGTTATAGGAATTACAGGCAGCAATGGAAAAACCATTGTGAAGGAATGGTTGTATCAATTGCTGAGCCCGGACCGTG
TGGTAACCCGTTCGCCACGTAGCTATAATTCACAGATAGGTGTGCCACTTTCGGTATGGTTGATGAATGAACGCACTGAG
TTGGCTATTTTTGAAGCGGGTATTTCCGAAATGGGGGAAATGGAGGCGTTGCAGACTATCATTAAACCTACTGTGGGGAT
TTTGACTAATATTGGTGGTGCGCACCAAGAGAACTTTTTCTCTTTACAGGATAAATGTATGGAGAAGCTTACTTTGTTCA
AAGACTGTGACGTCATCATTTATGATGGCGATAACGAACTGATCAGTTCGTGTGTGGCAAAATCTCTTTTTACCTCGCGT
GAGATTGCTTGGTCGAAAAAGGACAATGAACGTCCGTTGTTTATTGAGTCCATTCAAAAAGGGGCACATGCTACCACTAT
TAAATACCGTTATCTGGGGATGCCGAATGAATTTAGTATTCCTTTTATAGATGACGCTTCTATTGAGAATTCGCTGCATT
GTCTGGCTGTGGCTTTGTATATGATGGTTTCCCCTGAACAAATAACCGAGCGCATGGCGCGTTTGGAACAGATTGCTATG
CGTCTGGAGGTAAAAGAGGGCAAGAATGGCTGTGTGTTGATCAATGATAGTTATAATTCGGATTTGGCTTCTTTGGATAT
TGCTCTTGACTTTATGTCGCGTCGTTCTGATGATAAAGGAAAAAAACGGACACTTATCCTCTCGGATATGCTTGAAACAG
GCCAGAGCGGCAAACTGCTTTATCGTCAGGTAGCCGAATTGGTACATAGCCGGGGAGTAGAGAAGATTATCGGGGTAGGA
GAGGAAATTCGGACTGCTGCTGCCCGTTTTGAGATAGAAAAGTATTTTTTCCGTACTACAGAAGAACTGTTGGAGTCGGA
TTTGCTGGCTGGGCTGCGTAATGAGGTGATTTTGGTAAAAGGTTCGCGGGCTTTTCATTTTGACCGGATTTCAGATCGTT
TGGAACTGAAAGTGCATGAAACCATTTTGGAGATCAATTTGAATGCTTTGGTTGATAACTTGAATTATTATCGCAGCAAA
CTGAAACCGGAAACAAAAATGGTATGTATGGTGAAGGCTTCTGCATACGGTGCCGGTTCATACGAGATAGCTAAGACACT
GCAAGATCATCGTGTGGATTACTTGGCAGTAGCTGTGGCTGATGAAGGTTCGGATCTGAGGAAAGCGGGAATTACCTGTT
CCATTATGATTATGAATCCTGAGTTGACAGCATTCAAGACCATGTTTGATTATAAATTGGAACCCGAGGTTTACAGTTTC
CATTTATTGAATGAACTGATTAAAGCTGCCGAAAAAGAAGGGGTAACGAATTTCCCCATTCATATTAAATTGGATACGGG
AATGCACCGTTTGGGTTTTGCACCCGAAGAGATTCCGGAACTGATAGACCGTCTGAAGAAACAGACAGCTGTTATTCCAC
GTTCTGTATTCTCCCATTTGGTAGGCAGTGACGGGGCTCAGTTTGATTCGTTTACGCGCAGACAGATAGAAATGTTTGAA
GCTGCTTCTGAATGTTTGCAGGAGGCTTTTCAGCATAAGATATTGCGTCATATCTGTAATACAGCCGGGATAGAACGTTA
TCCGGGTGCTCAGTTCGATATGGTGCGTTTGGGAATCGGTCTTTATGGAATTGATCCGTTTACCAATCAGATCATCCATA
ATGTAAGTACATTAAAAACCACTATTCTTCAGATTCATGAGGTTCCTAAGGAGGAAACAGTGGGGTATAGTCGTAAAGGA
CATTTGGAAAGGGATTCCCGCATTGCCGCTATTCCTATCGGCTATGCCGACGGGCTGAACCGACGTTTGGGAAATGGACA
TGCCTACTGTTTGGTGAATGGGCAGAAAGCGCCATACGTGGGTAATATCTGTATGGATGTATGCATGATTGATGTGACGG
ATATTGATTGTAAGGAAGGGGATAAAACTATCATTTTCGGAGATGATTTACCGGTCACTGTCCTGTCAGAGATTCTGGAA
ACTATTCCATACGAGATCTTGACCAGTGTGTCTAATAGGGTAAAACGAGTTTATTACCAGAATTAA

Upstream 100 bases:

>100_bases
AATCTGAAACATATCGCAAATTTTTAACTCAAATAGTGTTAAAGATAGAGCGACTTAAAGAAAAGTTCCCGTATTTTGAC
CTTCAAAAAGAATTAGAACA

Downstream 100 bases:

>100_bases
CGAAAAAAAGAACGAAAGAAAAAGACTTGAAAAGGATGAACATACGTTACTTTTGCGTATCTTTAGGAAGTTACTAAAAA
TAGATAGCTATGAAACGTAT

Product: putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 821; Mature: 820

Protein sequence:

>821_residues
MSSSIENIEKVLGAKRFGDRSAQIDWILTDSRSLCFPEETLFFALKTKRNDGHKYLPELYERGVRNFVVGELPADMKSFQ
DANFLQLANPLKGLQKLAEKHREQFQIPVIGITGSNGKTIVKEWLYQLLSPDRVVTRSPRSYNSQIGVPLSVWLMNERTE
LAIFEAGISEMGEMEALQTIIKPTVGILTNIGGAHQENFFSLQDKCMEKLTLFKDCDVIIYDGDNELISSCVAKSLFTSR
EIAWSKKDNERPLFIESIQKGAHATTIKYRYLGMPNEFSIPFIDDASIENSLHCLAVALYMMVSPEQITERMARLEQIAM
RLEVKEGKNGCVLINDSYNSDLASLDIALDFMSRRSDDKGKKRTLILSDMLETGQSGKLLYRQVAELVHSRGVEKIIGVG
EEIRTAAARFEIEKYFFRTTEELLESDLLAGLRNEVILVKGSRAFHFDRISDRLELKVHETILEINLNALVDNLNYYRSK
LKPETKMVCMVKASAYGAGSYEIAKTLQDHRVDYLAVAVADEGSDLRKAGITCSIMIMNPELTAFKTMFDYKLEPEVYSF
HLLNELIKAAEKEGVTNFPIHIKLDTGMHRLGFAPEEIPELIDRLKKQTAVIPRSVFSHLVGSDGAQFDSFTRRQIEMFE
AASECLQEAFQHKILRHICNTAGIERYPGAQFDMVRLGIGLYGIDPFTNQIIHNVSTLKTTILQIHEVPKEETVGYSRKG
HLERDSRIAAIPIGYADGLNRRLGNGHAYCLVNGQKAPYVGNICMDVCMIDVTDIDCKEGDKTIIFGDDLPVTVLSEILE
TIPYEILTSVSNRVKRVYYQN

Sequences:

>Translated_821_residues
MSSSIENIEKVLGAKRFGDRSAQIDWILTDSRSLCFPEETLFFALKTKRNDGHKYLPELYERGVRNFVVGELPADMKSFQ
DANFLQLANPLKGLQKLAEKHREQFQIPVIGITGSNGKTIVKEWLYQLLSPDRVVTRSPRSYNSQIGVPLSVWLMNERTE
LAIFEAGISEMGEMEALQTIIKPTVGILTNIGGAHQENFFSLQDKCMEKLTLFKDCDVIIYDGDNELISSCVAKSLFTSR
EIAWSKKDNERPLFIESIQKGAHATTIKYRYLGMPNEFSIPFIDDASIENSLHCLAVALYMMVSPEQITERMARLEQIAM
RLEVKEGKNGCVLINDSYNSDLASLDIALDFMSRRSDDKGKKRTLILSDMLETGQSGKLLYRQVAELVHSRGVEKIIGVG
EEIRTAAARFEIEKYFFRTTEELLESDLLAGLRNEVILVKGSRAFHFDRISDRLELKVHETILEINLNALVDNLNYYRSK
LKPETKMVCMVKASAYGAGSYEIAKTLQDHRVDYLAVAVADEGSDLRKAGITCSIMIMNPELTAFKTMFDYKLEPEVYSF
HLLNELIKAAEKEGVTNFPIHIKLDTGMHRLGFAPEEIPELIDRLKKQTAVIPRSVFSHLVGSDGAQFDSFTRRQIEMFE
AASECLQEAFQHKILRHICNTAGIERYPGAQFDMVRLGIGLYGIDPFTNQIIHNVSTLKTTILQIHEVPKEETVGYSRKG
HLERDSRIAAIPIGYADGLNRRLGNGHAYCLVNGQKAPYVGNICMDVCMIDVTDIDCKEGDKTIIFGDDLPVTVLSEILE
TIPYEILTSVSNRVKRVYYQN
>Mature_820_residues
SSSIENIEKVLGAKRFGDRSAQIDWILTDSRSLCFPEETLFFALKTKRNDGHKYLPELYERGVRNFVVGELPADMKSFQD
ANFLQLANPLKGLQKLAEKHREQFQIPVIGITGSNGKTIVKEWLYQLLSPDRVVTRSPRSYNSQIGVPLSVWLMNERTEL
AIFEAGISEMGEMEALQTIIKPTVGILTNIGGAHQENFFSLQDKCMEKLTLFKDCDVIIYDGDNELISSCVAKSLFTSRE
IAWSKKDNERPLFIESIQKGAHATTIKYRYLGMPNEFSIPFIDDASIENSLHCLAVALYMMVSPEQITERMARLEQIAMR
LEVKEGKNGCVLINDSYNSDLASLDIALDFMSRRSDDKGKKRTLILSDMLETGQSGKLLYRQVAELVHSRGVEKIIGVGE
EIRTAAARFEIEKYFFRTTEELLESDLLAGLRNEVILVKGSRAFHFDRISDRLELKVHETILEINLNALVDNLNYYRSKL
KPETKMVCMVKASAYGAGSYEIAKTLQDHRVDYLAVAVADEGSDLRKAGITCSIMIMNPELTAFKTMFDYKLEPEVYSFH
LLNELIKAAEKEGVTNFPIHIKLDTGMHRLGFAPEEIPELIDRLKKQTAVIPRSVFSHLVGSDGAQFDSFTRRQIEMFEA
ASECLQEAFQHKILRHICNTAGIERYPGAQFDMVRLGIGLYGIDPFTNQIIHNVSTLKTTILQIHEVPKEETVGYSRKGH
LERDSRIAAIPIGYADGLNRRLGNGHAYCLVNGQKAPYVGNICMDVCMIDVTDIDCKEGDKTIIFGDDLPVTVLSEILET
IPYEILTSVSNRVKRVYYQN

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=368, Percent_Identity=33.695652173913, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=26.5582655826558, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1786274, Length=438, Percent_Identity=24.4292237442922, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 92754; Mature: 92623

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSIENIEKVLGAKRFGDRSAQIDWILTDSRSLCFPEETLFFALKTKRNDGHKYLPELY
CCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHEEEEEEECCCCCCHHHHHHH
ERGVRNFVVGELPADMKSFQDANFLQLANPLKGLQKLAEKHREQFQIPVIGITGSNGKTI
HCCHHHCEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECEEEEEECCCCHHH
VKEWLYQLLSPDRVVTRSPRSYNSQIGVPLSVWLMNERTELAIFEAGISEMGEMEALQTI
HHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEEECCCCEEEEEHHCHHHHHHHHHHHHH
IKPTVGILTNIGGAHQENFFSLQDKCMEKLTLFKDCDVIIYDGDNELISSCVAKSLFTSR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
EIAWSKKDNERPLFIESIQKGAHATTIKYRYLGMPNEFSIPFIDDASIENSLHCLAVALY
HHEECCCCCCCCCHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
MMVSPEQITERMARLEQIAMRLEVKEGKNGCVLINDSYNSDLASLDIALDFMSRRSDDKG
HHCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
KKRTLILSDMLETGQSGKLLYRQVAELVHSRGVEKIIGVGEEIRTAAARFEIEKYFFRTT
CCEEEEHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EELLESDLLAGLRNEVILVKGSRAFHFDRISDRLELKVHETILEINLNALVDNLNYYRSK
HHHHHHHHHHCCCCCEEEEECCCEEEHHHHCCHHHHHEEHHHHHEEHHHHHHHHHHHHHH
LKPETKMVCMVKASAYGAGSYEIAKTLQDHRVDYLAVAVADEGSDLRKAGITCSIMIMNP
CCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCHHHCCCEEEEEEECC
ELTAFKTMFDYKLEPEVYSFHLLNELIKAAEKEGVTNFPIHIKLDTGMHRLGFAPEEIPE
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCHHHHHH
LIDRLKKQTAVIPRSVFSHLVGSDGAQFDSFTRRQIEMFEAASECLQEAFQHKILRHICN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAGIERYPGAQFDMVRLGIGLYGIDPFTNQIIHNVSTLKTTILQIHEVPKEETVGYSRKG
HCCCCCCCCCCEEHEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
HLERDSRIAAIPIGYADGLNRRLGNGHAYCLVNGQKAPYVGNICMDVCMIDVTDIDCKEG
CCCCCCEEEEEECCCCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHHHEEEECCCCCCC
DKTIIFGDDLPVTVLSEILETIPYEILTSVSNRVKRVYYQN
CEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSSIENIEKVLGAKRFGDRSAQIDWILTDSRSLCFPEETLFFALKTKRNDGHKYLPELY
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHEEEEEEECCCCCCHHHHHHH
ERGVRNFVVGELPADMKSFQDANFLQLANPLKGLQKLAEKHREQFQIPVIGITGSNGKTI
HCCHHHCEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECEEEEEECCCCHHH
VKEWLYQLLSPDRVVTRSPRSYNSQIGVPLSVWLMNERTELAIFEAGISEMGEMEALQTI
HHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEEECCCCEEEEEHHCHHHHHHHHHHHHH
IKPTVGILTNIGGAHQENFFSLQDKCMEKLTLFKDCDVIIYDGDNELISSCVAKSLFTSR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
EIAWSKKDNERPLFIESIQKGAHATTIKYRYLGMPNEFSIPFIDDASIENSLHCLAVALY
HHEECCCCCCCCCHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
MMVSPEQITERMARLEQIAMRLEVKEGKNGCVLINDSYNSDLASLDIALDFMSRRSDDKG
HHCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
KKRTLILSDMLETGQSGKLLYRQVAELVHSRGVEKIIGVGEEIRTAAARFEIEKYFFRTT
CCEEEEHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EELLESDLLAGLRNEVILVKGSRAFHFDRISDRLELKVHETILEINLNALVDNLNYYRSK
HHHHHHHHHHCCCCCEEEEECCCEEEHHHHCCHHHHHEEHHHHHEEHHHHHHHHHHHHHH
LKPETKMVCMVKASAYGAGSYEIAKTLQDHRVDYLAVAVADEGSDLRKAGITCSIMIMNP
CCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCHHHCCCEEEEEEECC
ELTAFKTMFDYKLEPEVYSFHLLNELIKAAEKEGVTNFPIHIKLDTGMHRLGFAPEEIPE
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCHHHHHH
LIDRLKKQTAVIPRSVFSHLVGSDGAQFDSFTRRQIEMFEAASECLQEAFQHKILRHICN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAGIERYPGAQFDMVRLGIGLYGIDPFTNQIIHNVSTLKTTILQIHEVPKEETVGYSRKG
HCCCCCCCCCCEEHEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
HLERDSRIAAIPIGYADGLNRRLGNGHAYCLVNGQKAPYVGNICMDVCMIDVTDIDCKEG
CCCCCCEEEEEECCCCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHHHEEEECCCCCCC
DKTIIFGDDLPVTVLSEILETIPYEILTSVSNRVKRVYYQN
CEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]