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The map label for this gene is trkH [H]

Identifier: 150004315

GI number: 150004315

Start: 2257113

End: 2258567

Strand: Reverse

Name: trkH [H]

Synonym: BVU_1761

Alternate gene names: 150004315

Gene position: 2258567-2257113 (Counterclockwise)

Preceding gene: 150004316

Following gene: 150004314

Centisome position: 43.74

GC content: 40.89

Gene sequence:

>1455_bases
ATGATAAATGCAAAAATGATAGCCCGGATTATGGGGGCGTTATTCTTCATCGAAGCGGGGTTTCTTATTCTATGCTCGTT
TCTCGCTGTCTATTATAATGAATCAGATATTTCAGCTTTCCTATATTCTGCCGCAATAACAGCCGGAGCAGGTAGCATAG
CCGCTTTAGCAGGGAAAAATGCAGAAAAGAGAATCAGCCGCCGCGATGGATACGTTATTGTAACCCTTGCCTGGGTGTTT
TTTTCTTTATTCGGTATGCTTCCATTCTATCTAAGCGGATATATTCCCACTATAACGGATGCTTTTTTTGAAACCATGTC
AGGATTCACCACCACCGGAGCAAGTATTTTGGACAATATAGAGTCATTGCCACACGGGCTTTTGTTCTGGCGAAGTATGA
CACAATGGATCGGAGGATTAGGAATTGTCTTTTTTACTATTGCCGTATTACCGATTTTCGGAGTAGGCAGTGTACAATTA
TTTGCAGCGGAAGCCACCGGTCCCACCCATGATAAAGTACATCCGCGTATTGGAGTTACGGCCAAATGGATTTGGACTAT
CTATTTGGGGCTGACCATTACAGAGATTATTCTGCTGGTTGCTGGAGGCATGAACTTTTTCGACAGTGTATGTCATTCTC
TGACTACTACCGCCACAGGAGGATATTCAACCAAACAAAATAGCATTGCCGCCTTCAACTCTCCTTACATAGAATATATA
ATTACGCTATTCATGTTTTTGGCAGGTATCAATTTCACCTTACTATATCTACTGTTCTTAAAAGGAAATTTCAAACGCTT
ATTCCAAAATACAGAACTCCACTGGTATTTGGGAACTGTGGGATTTTTTACCCTTTTCACTACCGTCACTCTTATTTTCA
CCAGTCCGTTCAGTATTGAAGAATCTTTCCGTAAAGCCATATTTCAGGTTGTTTCCTTACAAACCACTACCGGATTCATT
TCTGCAGATTATATGACCTGGGTACCTGTACTTTGGACATTAATGTGCATCATCATGCTGTTTGGAGCTTGTGCCGGATC
CACCACAGGAGGAATAAAATGTATACGCATAGCCATTATGAGCCGTGTTTCTAAAAATGAATTCAAACATATCATTCATC
CCAATGCTATACTTCCTGTACGTATCAATCGCCAAGTTATTTCATCAACAACCAAGTCAGCAGTACTTGCATTCATTTTT
CTATATATGGCTATTATTTTTATTGGATGGCTGGTTCTTATGCTGTTTGGAGTAGGGTTTGAAGAAGCTTATAGCGTAGT
CATTTCCAGTTTGGGCAATGTAGGACCAGGTATTGGAAAATGCGGCCCTTCCTATTCATGGAACGGGTTGCCGGATGCAG
CAAAATGGATAAGTGCAATATTGATGCTGATAGGGCGTTTGGAATTATTTACCGTACTTCTGCTCTTCATGCCGAGTTTT
TGGAAAAAGCATTGA

Upstream 100 bases:

>100_bases
GGATACTGGTGACAGGTAATACCGTCATCCAACCTAACGACCATGTCGTAGTATTCTGTCTAGGTATGATGATTAAGAAA
ATAGAAAAATTCTTCAATTG

Downstream 100 bases:

>100_bases
CATTTACGTCCTATAACCATTTTTATACATAAATAATTCAAAAAATCTCAATGAAGCTTCAAATATTGGCTATCTTTGCA
CCCTCATTTAAAGGGTAACA

Product: Trk system K+ uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MINAKMIARIMGALFFIEAGFLILCSFLAVYYNESDISAFLYSAAITAGAGSIAALAGKNAEKRISRRDGYVIVTLAWVF
FSLFGMLPFYLSGYIPTITDAFFETMSGFTTTGASILDNIESLPHGLLFWRSMTQWIGGLGIVFFTIAVLPIFGVGSVQL
FAAEATGPTHDKVHPRIGVTAKWIWTIYLGLTITEIILLVAGGMNFFDSVCHSLTTTATGGYSTKQNSIAAFNSPYIEYI
ITLFMFLAGINFTLLYLLFLKGNFKRLFQNTELHWYLGTVGFFTLFTTVTLIFTSPFSIEESFRKAIFQVVSLQTTTGFI
SADYMTWVPVLWTLMCIIMLFGACAGSTTGGIKCIRIAIMSRVSKNEFKHIIHPNAILPVRINRQVISSTTKSAVLAFIF
LYMAIIFIGWLVLMLFGVGFEEAYSVVISSLGNVGPGIGKCGPSYSWNGLPDAAKWISAILMLIGRLELFTVLLLFMPSF
WKKH

Sequences:

>Translated_484_residues
MINAKMIARIMGALFFIEAGFLILCSFLAVYYNESDISAFLYSAAITAGAGSIAALAGKNAEKRISRRDGYVIVTLAWVF
FSLFGMLPFYLSGYIPTITDAFFETMSGFTTTGASILDNIESLPHGLLFWRSMTQWIGGLGIVFFTIAVLPIFGVGSVQL
FAAEATGPTHDKVHPRIGVTAKWIWTIYLGLTITEIILLVAGGMNFFDSVCHSLTTTATGGYSTKQNSIAAFNSPYIEYI
ITLFMFLAGINFTLLYLLFLKGNFKRLFQNTELHWYLGTVGFFTLFTTVTLIFTSPFSIEESFRKAIFQVVSLQTTTGFI
SADYMTWVPVLWTLMCIIMLFGACAGSTTGGIKCIRIAIMSRVSKNEFKHIIHPNAILPVRINRQVISSTTKSAVLAFIF
LYMAIIFIGWLVLMLFGVGFEEAYSVVISSLGNVGPGIGKCGPSYSWNGLPDAAKWISAILMLIGRLELFTVLLLFMPSF
WKKH
>Mature_484_residues
MINAKMIARIMGALFFIEAGFLILCSFLAVYYNESDISAFLYSAAITAGAGSIAALAGKNAEKRISRRDGYVIVTLAWVF
FSLFGMLPFYLSGYIPTITDAFFETMSGFTTTGASILDNIESLPHGLLFWRSMTQWIGGLGIVFFTIAVLPIFGVGSVQL
FAAEATGPTHDKVHPRIGVTAKWIWTIYLGLTITEIILLVAGGMNFFDSVCHSLTTTATGGYSTKQNSIAAFNSPYIEYI
ITLFMFLAGINFTLLYLLFLKGNFKRLFQNTELHWYLGTVGFFTLFTTVTLIFTSPFSIEESFRKAIFQVVSLQTTTGFI
SADYMTWVPVLWTLMCIIMLFGACAGSTTGGIKCIRIAIMSRVSKNEFKHIIHPNAILPVRINRQVISSTTKSAVLAFIF
LYMAIIFIGWLVLMLFGVGFEEAYSVVISSLGNVGPGIGKCGPSYSWNGLPDAAKWISAILMLIGRLELFTVLLLFMPSF
WKKH

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=482, Percent_Identity=36.7219917012448, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1787626, Length=460, Percent_Identity=32.3913043478261, Blast_Score=265, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53476; Mature: 53476

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAKMIARIMGALFFIEAGFLILCSFLAVYYNESDISAFLYSAAITAGAGSIAALAGKN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCCC
AEKRISRRDGYVIVTLAWVFFSLFGMLPFYLSGYIPTITDAFFETMSGFTTTGASILDNI
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
ESLPHGLLFWRSMTQWIGGLGIVFFTIAVLPIFGVGSVQLFAAEATGPTHDKVHPRIGVT
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCH
AKWIWTIYLGLTITEIILLVAGGMNFFDSVCHSLTTTATGGYSTKQNSIAAFNSPYIEYI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHH
ITLFMFLAGINFTLLYLLFLKGNFKRLFQNTELHWYLGTVGFFTLFTTVTLIFTSPFSIE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHH
ESFRKAIFQVVSLQTTTGFISADYMTWVPVLWTLMCIIMLFGACAGSTTGGIKCIRIAIM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SRVSKNEFKHIIHPNAILPVRINRQVISSTTKSAVLAFIFLYMAIIFIGWLVLMLFGVGF
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EEAYSVVISSLGNVGPGIGKCGPSYSWNGLPDAAKWISAILMLIGRLELFTVLLLFMPSF
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WKKH
HCCC
>Mature Secondary Structure
MINAKMIARIMGALFFIEAGFLILCSFLAVYYNESDISAFLYSAAITAGAGSIAALAGKN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCCC
AEKRISRRDGYVIVTLAWVFFSLFGMLPFYLSGYIPTITDAFFETMSGFTTTGASILDNI
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
ESLPHGLLFWRSMTQWIGGLGIVFFTIAVLPIFGVGSVQLFAAEATGPTHDKVHPRIGVT
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCH
AKWIWTIYLGLTITEIILLVAGGMNFFDSVCHSLTTTATGGYSTKQNSIAAFNSPYIEYI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHH
ITLFMFLAGINFTLLYLLFLKGNFKRLFQNTELHWYLGTVGFFTLFTTVTLIFTSPFSIE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHH
ESFRKAIFQVVSLQTTTGFISADYMTWVPVLWTLMCIIMLFGACAGSTTGGIKCIRIAIM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SRVSKNEFKHIIHPNAILPVRINRQVISSTTKSAVLAFIFLYMAIIFIGWLVLMLFGVGF
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EEAYSVVISSLGNVGPGIGKCGPSYSWNGLPDAAKWISAILMLIGRLELFTVLLLFMPSF
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WKKH
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]