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The map label for this gene is fba [H]

Identifier: 150004230

GI number: 150004230

Start: 2158430

End: 2159530

Strand: Direct

Name: fba [H]

Synonym: BVU_1671

Alternate gene names: 150004230

Gene position: 2158430-2159530 (Clockwise)

Preceding gene: 150004228

Following gene: 150004232

Centisome position: 41.8

GC content: 41.33

Gene sequence:

>1101_bases
ATGAGATATTTTTGGTGTGAACTTGCCATAGTTAGCGCATTTATGATTACTTTTGCAGTGGAATTTAATTCACTAACAAT
TATAAATATTAGAACAATGGTTAATTACAAAGATTTAGGTCTGGTAAACACTAGAGATATGTTTGCTAAGGCTATCAAAG
GTGGATATGCAATTCCTGCATTCAACTTCAACAATATGGAACAGATGCAGGCTATCATCAAAGCTGCAGTAGAAACAAAA
TCTCCGGTTATTTTGCAGGTTTCAAAAGGTGCTCGTCAGTATGCTAACGCTACTTTGTTGCGTTACATGGCTCAGGGTGC
TGTAGAATATGCAAAAGAATTAGGTTGTGCAAAACCTGAAATCGTTCTTCACCTTGACCACGGAGATACTTTCGAAACTT
GCAAGAGCTGTATCGACTCAGGTTTCTCTTCTGTAATGATCGACGGTTCTCACCTGCCTTACGAAGAAAACGTAGCTTTG
ACTAAGAAGGTGGTTGACTACGCTCATCAGTTTGATGTAACTGTAGAAGGTGAATTGGGTGTATTGGCCGGTGTGGAAGA
TGAAGTTTCTTCTGATCATCATACTTATACTGACCCTGAAGAAGTAATTGATTTTGCTACTCGTACAGGTTGTGACTCAT
TGGCTATCTCTATCGGTACTTCTCACGGTGCATACAAATTTACTCCGGAACAGTGCCACATTGATCCTGCTACAGGTCGT
ATGGTTCCTCCTCCTTTGGCATTCGAAGTATTGGATGCTGTAATGGAAAAACTTCCGGGATTCCCCATCGTTCTTCATGG
TTCTTCATCAGTTCCTCAGGAAGAAGTTGAAACAATCAACAAGTATGGTGGTGCATTGAAGGCTGCTATCGGTATCCCTG
AAGAAGAATTGCGCAAGGCTGCCAAGTCTGCTGTTTGCAAAATCAACATTGACTCAGACTCTCGTTTGGCTATGACTGCT
GCTATCCGTCAGACTTTTGCTGAAAAACCGGCAGAATTCGACCCGCGTAAGTACTTAGGTCCGGCTCGTGACAATATGGA
AAAACTGTACAAGCACAAAATTATTAACGTGCTGGGTTCAGACAATAAATTGGCTGAATAA

Upstream 100 bases:

>100_bases
AAAGCCTTATTTTCTTCTTTTATAGTATTGTAAGGTAGACATTACAATATAATCAGTTTGTATGTTTTAGTGAAGAAAAT
AGTTAATAAAATCATTTTTT

Downstream 100 bases:

>100_bases
TTGATTCATCCTATATAAACAGAAAAAAGCTGCTTTCTTTATCGGAGGCAGCTTTTTTTGTTTTAAGACCGGTTTCGGTA
TTGAAGAGGGGACTTGCCTG

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRYFWCELAIVSAFMITFAVEFNSLTIINIRTMVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETK
SPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAKPEIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENVAL
TKKVVDYAHQFDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGR
MVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVPQEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRLAMTA
AIRQTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE

Sequences:

>Translated_366_residues
MRYFWCELAIVSAFMITFAVEFNSLTIINIRTMVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETK
SPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAKPEIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENVAL
TKKVVDYAHQFDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGR
MVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVPQEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRLAMTA
AIRQTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE
>Mature_366_residues
MRYFWCELAIVSAFMITFAVEFNSLTIINIRTMVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETK
SPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAKPEIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENVAL
TKKVVDYAHQFDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGR
MVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVPQEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRLAMTA
AIRQTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=330, Percent_Identity=34.8484848484849, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI87082041, Length=326, Percent_Identity=33.4355828220859, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1788072, Length=326, Percent_Identity=30.9815950920245, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 40242; Mature: 40242

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYFWCELAIVSAFMITFAVEFNSLTIINIRTMVNYKDLGLVNTRDMFAKAIKGGYAIPA
CCEEEHHHHHHHHHHHHHEEEECCEEEEEEEEEECHHHCCCCCHHHHHHHHHCCCEEEEC
FNFNNMEQMQAIIKAAVETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAKPE
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELG
EEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCC
VLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGR
EEECCCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEECHHHEECCCCCCC
MVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVPQEEVETINKYGGALKAAIGIPEEELRKA
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEHHCCCCHHHHHHH
AKSAVCKINIDSDSRLAMTAAIRQTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGS
HHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCC
DNKLAE
CCCCCC
>Mature Secondary Structure
MRYFWCELAIVSAFMITFAVEFNSLTIINIRTMVNYKDLGLVNTRDMFAKAIKGGYAIPA
CCEEEHHHHHHHHHHHHHEEEECCEEEEEEEEEECHHHCCCCCHHHHHHHHHCCCEEEEC
FNFNNMEQMQAIIKAAVETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAKPE
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELG
EEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCC
VLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGR
EEECCCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEECHHHEECCCCCCC
MVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVPQEEVETINKYGGALKAAIGIPEEELRKA
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEHHCCCCHHHHHHH
AKSAVCKINIDSDSRLAMTAAIRQTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGS
HHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCC
DNKLAE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]