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The map label for this gene is thiL [H]

Identifier: 150004165

GI number: 150004165

Start: 2084962

End: 2086002

Strand: Reverse

Name: thiL [H]

Synonym: BVU_1601

Alternate gene names: 150004165

Gene position: 2086002-2084962 (Counterclockwise)

Preceding gene: 150004166

Following gene: 150004164

Centisome position: 40.4

GC content: 42.36

Gene sequence:

>1041_bases
ATGCAGGAAATAAACAGAACAGAAATAGCGACCTTAGGTGAGTTCGGCCTCATTAAACATCTAACGAAGGATATCGAGTT
AAAAAATCCGGAAACCCAATATGGTGTGGGAGACGATGCAGCCGTATTGGAATTTAAAGATAAAGAGGTATTGGTGACCA
CAGACTTACTGATGGAAGGGGTACATTTTGATTTGGTTTATACCCCATTGAAACATTTGGGATATAAATCGGCCATCGTA
AACTTCTCGGACATTTATGCTATGAATGGTACTCCAAAACAAATCACAGTTTCTATCGCACTGTCCAAACGCTTTTGTAT
TGAAGATTTAGAACAGTTCTATGATGGGCTAAAACTGGCTTGTGAACTACACCATGTAGATATTGTGGGTGGAGATACAA
CTTCATCCGTAACCGGGCTCGCCATCAGTATTACTTGCATAGGTGAAGCGGACAAGGACAAAGTGGTTTATCGCAACGGC
GCACAAGATACAGACTTGATTTGTGTCAGCGGTGACTTGGGAGGAGCTTATATGGGACTTCAACTTCTAGAGCGTGAAAA
GGCTGTTTTCCAAGGAGAAAAAGAAGCAAATCCGGATTTTTCCGGAAAAGAATATATTTTGGAACGTCAGTTAAAGCCTG
AAGCACGTAAGGATATCATTGAGAAACTGGCAAAAGCGGGAATCAAGCCCACCGCTATGATGGATATTTCCGACGGCCTT
TCTTCGGAACTGCTACATATATGCTCACAAAGCGATACCGGCTGTCGCATTTACGAGGAAAGAATTCCCATTGATTACCA
AACGGCTGTAATGGCGGAAGAACTGAATATGAATGTGACAACATGTGCTTTAAATGGTGGTGAGGACTATGAGCTATTAT
TTACTGTACCTTTAACAGAGCATGAACGAGTTTCGGCTATAGAGGGTATAAAAGTGATTGGTCACATCACCAAACCGGAG
CTGGGATGTGCCCTGATTACCCGTGACGGACAAGAGTTTGAGCTGAAAGCGCAAGGTTGGAATCCACTAAAAGAAAAATA
A

Upstream 100 bases:

>100_bases
ATTGTGGAAGTTTCACACGAAGAGGTTCAGAAAGCGGCAGATGAAGCGCAACCGCGCATGACTACCATTATGCGTGAAAT
GATTAATCGAATTTAAGAAC

Downstream 100 bases:

>100_bases
TTTTAATTAAACAACACTGATAATAAGCACCTTATGTTTTTATCAGTGTTTTTTTTTAGAAATAGTTTGTAGTTTAAAAA
AGTTTCACTACCTTTGCAAC

Product: putative thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MQEINRTEIATLGEFGLIKHLTKDIELKNPETQYGVGDDAAVLEFKDKEVLVTTDLLMEGVHFDLVYTPLKHLGYKSAIV
NFSDIYAMNGTPKQITVSIALSKRFCIEDLEQFYDGLKLACELHHVDIVGGDTTSSVTGLAISITCIGEADKDKVVYRNG
AQDTDLICVSGDLGGAYMGLQLLEREKAVFQGEKEANPDFSGKEYILERQLKPEARKDIIEKLAKAGIKPTAMMDISDGL
SSELLHICSQSDTGCRIYEERIPIDYQTAVMAEELNMNVTTCALNGGEDYELLFTVPLTEHERVSAIEGIKVIGHITKPE
LGCALITRDGQEFELKAQGWNPLKEK

Sequences:

>Translated_346_residues
MQEINRTEIATLGEFGLIKHLTKDIELKNPETQYGVGDDAAVLEFKDKEVLVTTDLLMEGVHFDLVYTPLKHLGYKSAIV
NFSDIYAMNGTPKQITVSIALSKRFCIEDLEQFYDGLKLACELHHVDIVGGDTTSSVTGLAISITCIGEADKDKVVYRNG
AQDTDLICVSGDLGGAYMGLQLLEREKAVFQGEKEANPDFSGKEYILERQLKPEARKDIIEKLAKAGIKPTAMMDISDGL
SSELLHICSQSDTGCRIYEERIPIDYQTAVMAEELNMNVTTCALNGGEDYELLFTVPLTEHERVSAIEGIKVIGHITKPE
LGCALITRDGQEFELKAQGWNPLKEK
>Mature_346_residues
MQEINRTEIATLGEFGLIKHLTKDIELKNPETQYGVGDDAAVLEFKDKEVLVTTDLLMEGVHFDLVYTPLKHLGYKSAIV
NFSDIYAMNGTPKQITVSIALSKRFCIEDLEQFYDGLKLACELHHVDIVGGDTTSSVTGLAISITCIGEADKDKVVYRNG
AQDTDLICVSGDLGGAYMGLQLLEREKAVFQGEKEANPDFSGKEYILERQLKPEARKDIIEKLAKAGIKPTAMMDISDGL
SSELLHICSQSDTGCRIYEERIPIDYQTAVMAEELNMNVTTCALNGGEDYELLFTVPLTEHERVSAIEGIKVIGHITKPE
LGCALITRDGQEFELKAQGWNPLKEK

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=337, Percent_Identity=31.1572700296736, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 38270; Mature: 38270

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEINRTEIATLGEFGLIKHLTKDIELKNPETQYGVGDDAAVLEFKDKEVLVTTDLLMEG
CCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEEHHHHHCC
VHFDLVYTPLKHLGYKSAIVNFSDIYAMNGTPKQITVSIALSKRFCIEDLEQFYDGLKLA
CEEEEEEHHHHHCCCHHHCCCHHHEEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHEEE
CELHHVDIVGGDTTSSVTGLAISITCIGEADKDKVVYRNGAQDTDLICVSGDLGGAYMGL
EEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCEEEEEECCCCCHHHHH
QLLEREKAVFQGEKEANPDFSGKEYILERQLKPEARKDIIEKLAKAGIKPTAMMDISDGL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCH
SSELLHICSQSDTGCRIYEERIPIDYQTAVMAEELNMNVTTCALNGGEDYELLFTVPLTE
HHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEEEEECCCC
HERVSAIEGIKVIGHITKPELGCALITRDGQEFELKAQGWNPLKEK
CHHHHHHHCEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MQEINRTEIATLGEFGLIKHLTKDIELKNPETQYGVGDDAAVLEFKDKEVLVTTDLLMEG
CCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEEHHHHHCC
VHFDLVYTPLKHLGYKSAIVNFSDIYAMNGTPKQITVSIALSKRFCIEDLEQFYDGLKLA
CEEEEEEHHHHHCCCHHHCCCHHHEEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHEEE
CELHHVDIVGGDTTSSVTGLAISITCIGEADKDKVVYRNGAQDTDLICVSGDLGGAYMGL
EEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCEEEEEECCCCCHHHHH
QLLEREKAVFQGEKEANPDFSGKEYILERQLKPEARKDIIEKLAKAGIKPTAMMDISDGL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCH
SSELLHICSQSDTGCRIYEERIPIDYQTAVMAEELNMNVTTCALNGGEDYELLFTVPLTE
HHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEEEEECCCC
HERVSAIEGIKVIGHITKPELGCALITRDGQEFELKAQGWNPLKEK
CHHHHHHHCEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]