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The map label for this gene is wecB [H]

Identifier: 150004107

GI number: 150004107

Start: 2030486

End: 2031667

Strand: Direct

Name: wecB [H]

Synonym: BVU_1542

Alternate gene names: 150004107

Gene position: 2030486-2031667 (Clockwise)

Preceding gene: 150004106

Following gene: 150004108

Centisome position: 39.33

GC content: 45.18

Gene sequence:

>1182_bases
ATGGAATTAAAAACTGACTATTCAGATATAAAATTTGCGGAAAACGGCAAGTTGAAACTTTTGATAATTGTAGGAACAAG
ACCTGAAATTATCCGCCTTGCAGCCGTTATCAGTAAGTGCCGCATCTATTTCGACACAATCCTTGCTCATACAGGCCAGA
ACTATGACTATAACTTGAACGGCATCTTTTTCAAAGACCTGAAGTTGAAAGAACCAGAAGTGTATATGGATGCCGTTGGC
GATGACCTCGGTTCAACAATGGGAAATATCATAAGTGCTTCCTATAAACTCATGTCGCAGGTAAAGCCCGATGCTGTACT
TGTTCTTGGCGATACAAACTCATGCCTGTCAGTTATCGGAGCAAAGCGTCTGCACATACCTATCTTCCACATGGAAGCAG
GTAATAGATGCAAGGATGAGAACCTTCCGGAAGAGACAAACCGCCGTATCGTCGATATCATCAGTGACGTCAACCTTGCC
TATAGCGAGCATGCTCGCCGCTATCTTGCAGAATGCGGATTGCCGAAGGAGAGGACATACGTTACCGGTTCACCAATGGC
GGAAGTCCTTCATAATAATCTTGAAGAGATTGAGGCAAGCGACATTCATAACCGTCTCGGCCTTGAAAAGGGCAAATATA
TCCTTCTTAGCGCCCACCGTGAGGAGAATATCGACTCAGAAAAGAACTTCACTTCATTGTTCCGGGCAATCAATGCGATG
GCAGAGAAGTACGATATGCCGGTGCTTTATAGTTGCCACCCAAGAAGCCGCAAACGCCTTGCCGCAAACGGATTCCAATT
AGACAAAAGAGTAATTCAGCACGAGCCTCTCGGATTTCATGATTATAACTGTCTCCAGATGAACGCATTTGCCGTTGTCA
GCGACAGTGGAACATTGCCAGAGGAGAGTTCATTCTTCACATCAGTAGGCCATTCGTTCCCGGCAATCTGCATCCGCACG
AGCACAGAGCGTCCGGAAGCCCTCGACAAGGCATGCTTCATATTGGCAGGCATTGACGAAAAATCATTGCTTCAGGCGGT
TGATACAGCCGTAGAGATGAACAAGAATCAAGATAACGGCATTCCAGTGCCAAACTATGTTGATGAGAACGTATCAACAA
AGACCGTTAAACTCATCCAAAGTTACACCGGCGTTGTCAATAAAATGATATGGAGAAAATAA

Upstream 100 bases:

>100_bases
TACGATTGAGGTCCTTGAAAGCGGAACGGTAATCTTTGAAGTTAAGGATGGACCGTACACACCACTTACTCCTAAAAATA
CAATGACAAAATAAAATATT

Downstream 100 bases:

>100_bases
TTAAGAATTTTACCTAAATCATCAATAAATAATGAAAGTTCTTTATTCTCATCATGGCATGAAAGGAAAAAATGGATGGG
GACGAACCTTTTATATGGCA

Product: putative UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MELKTDYSDIKFAENGKLKLLIIVGTRPEIIRLAAVISKCRIYFDTILAHTGQNYDYNLNGIFFKDLKLKEPEVYMDAVG
DDLGSTMGNIISASYKLMSQVKPDAVLVLGDTNSCLSVIGAKRLHIPIFHMEAGNRCKDENLPEETNRRIVDIISDVNLA
YSEHARRYLAECGLPKERTYVTGSPMAEVLHNNLEEIEASDIHNRLGLEKGKYILLSAHREENIDSEKNFTSLFRAINAM
AEKYDMPVLYSCHPRSRKRLAANGFQLDKRVIQHEPLGFHDYNCLQMNAFAVVSDSGTLPEESSFFTSVGHSFPAICIRT
STERPEALDKACFILAGIDEKSLLQAVDTAVEMNKNQDNGIPVPNYVDENVSTKTVKLIQSYTGVVNKMIWRK

Sequences:

>Translated_393_residues
MELKTDYSDIKFAENGKLKLLIIVGTRPEIIRLAAVISKCRIYFDTILAHTGQNYDYNLNGIFFKDLKLKEPEVYMDAVG
DDLGSTMGNIISASYKLMSQVKPDAVLVLGDTNSCLSVIGAKRLHIPIFHMEAGNRCKDENLPEETNRRIVDIISDVNLA
YSEHARRYLAECGLPKERTYVTGSPMAEVLHNNLEEIEASDIHNRLGLEKGKYILLSAHREENIDSEKNFTSLFRAINAM
AEKYDMPVLYSCHPRSRKRLAANGFQLDKRVIQHEPLGFHDYNCLQMNAFAVVSDSGTLPEESSFFTSVGHSFPAICIRT
STERPEALDKACFILAGIDEKSLLQAVDTAVEMNKNQDNGIPVPNYVDENVSTKTVKLIQSYTGVVNKMIWRK
>Mature_393_residues
MELKTDYSDIKFAENGKLKLLIIVGTRPEIIRLAAVISKCRIYFDTILAHTGQNYDYNLNGIFFKDLKLKEPEVYMDAVG
DDLGSTMGNIISASYKLMSQVKPDAVLVLGDTNSCLSVIGAKRLHIPIFHMEAGNRCKDENLPEETNRRIVDIISDVNLA
YSEHARRYLAECGLPKERTYVTGSPMAEVLHNNLEEIEASDIHNRLGLEKGKYILLSAHREENIDSEKNFTSLFRAINAM
AEKYDMPVLYSCHPRSRKRLAANGFQLDKRVIQHEPLGFHDYNCLQMNAFAVVSDSGTLPEESSFFTSVGHSFPAICIRT
STERPEALDKACFILAGIDEKSLLQAVDTAVEMNKNQDNGIPVPNYVDENVSTKTVKLIQSYTGVVNKMIWRK

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=351, Percent_Identity=26.4957264957265, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 44206; Mature: 44206

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKTDYSDIKFAENGKLKLLIIVGTRPEIIRLAAVISKCRIYFDTILAHTGQNYDYNLN
CCCCCCCCCCEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GIFFKDLKLKEPEVYMDAVGDDLGSTMGNIISASYKLMSQVKPDAVLVLGDTNSCLSVIG
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHC
AKRLHIPIFHMEAGNRCKDENLPEETNRRIVDIISDVNLAYSEHARRYLAECGLPKERTY
CCEEEEEEEEECCCCCCCCCCCCHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEE
VTGSPMAEVLHNNLEEIEASDIHNRLGLEKGKYILLSAHREENIDSEKNFTSLFRAINAM
ECCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
AEKYDMPVLYSCHPRSRKRLAANGFQLDKRVIQHEPLGFHDYNCLQMNAFAVVSDSGTLP
HHHCCCCEEEECCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCC
EESSFFTSVGHSFPAICIRTSTERPEALDKACFILAGIDEKSLLQAVDTAVEMNKNQDNG
CCHHHHHHHCCCCCEEEEECCCCCCHHHHHHEEEEECCCHHHHHHHHHHHHHCCCCCCCC
IPVPNYVDENVSTKTVKLIQSYTGVVNKMIWRK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELKTDYSDIKFAENGKLKLLIIVGTRPEIIRLAAVISKCRIYFDTILAHTGQNYDYNLN
CCCCCCCCCCEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GIFFKDLKLKEPEVYMDAVGDDLGSTMGNIISASYKLMSQVKPDAVLVLGDTNSCLSVIG
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHC
AKRLHIPIFHMEAGNRCKDENLPEETNRRIVDIISDVNLAYSEHARRYLAECGLPKERTY
CCEEEEEEEEECCCCCCCCCCCCHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEE
VTGSPMAEVLHNNLEEIEASDIHNRLGLEKGKYILLSAHREENIDSEKNFTSLFRAINAM
ECCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
AEKYDMPVLYSCHPRSRKRLAANGFQLDKRVIQHEPLGFHDYNCLQMNAFAVVSDSGTLP
HHHCCCCEEEECCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCC
EESSFFTSVGHSFPAICIRTSTERPEALDKACFILAGIDEKSLLQAVDTAVEMNKNQDNG
CCHHHHHHHCCCCCEEEEECCCCCCHHHHHHEEEEECCCHHHHHHHHHHHHHCCCCCCCC
IPVPNYVDENVSTKTVKLIQSYTGVVNKMIWRK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA