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The map label for this gene is ptp [H]

Identifier: 150004031

GI number: 150004031

Start: 1945028

End: 1946338

Strand: Reverse

Name: ptp [H]

Synonym: BVU_1466

Alternate gene names: 150004031

Gene position: 1946338-1945028 (Counterclockwise)

Preceding gene: 150004039

Following gene: 150004025

Centisome position: 37.7

GC content: 43.78

Gene sequence:

>1311_bases
ATGAAACACACACTCTCTTTTATGGTATGGGCAATACTGGCTGTCTTATTGCCTTTACAAATGGCCCAGGCCGCAGCTCC
TCCCACTGAATTACAGAAAAGACTTCAAAATCTTCCGGACATCAGTGACATTAAACCAATGCAAAGTGATGCCTATCCGG
AGAAATATGTATTCTTCATTAATCAACTATTGGATCCGCATCACCCCGAAGCAGGGAATTTCAAGCAAAGGGTTATTCTC
TCGCATGTAGGTTTTGACCGCCCTACCGTACTGGTTACCGAAGGCTATACCGCCCATTATGCCACCCATCCGCGTTATCA
AGAAGAGTTATCCAAATTATTCAACGCCAATCTGGTATTCGTGGAATACCGTTATTTTGGTGAGTCCATGCCGAAGCCCT
GCAACTGGGATTATCTCACGGTTGAAAATTCACTGTATGATTTGCATCATGTAACCACGACCTTGAAACAACTATACGAT
GAGAAATGGATAGCTACCGGAATCAGCAAAGGCGGACAGACTACGATGTTCTACCGCACTTACTTTCCCGATGATGTGGA
TATCTCCGTACCTTACGTAGCCCCCCTCAACCAATCATTGGAGGACGGCCGTCACGAACCGTTCATTGCCAATAAAGTTT
CGACTCCCGAAAACCGTAAACGAGTTGAAAACTTTCAACTGGAAGTACTTAAACGCAAGAGCCGGCTGCTGCCGATATTC
GAAAAATATTGCTCGGATAAAGGATATACCTTCCGCATTCCTATAGCCGAAGTATACGACTTCAATGTATTGGAATACTC
ATTTGCCCTATGGCAATGGGGAACTCCTGTAAATAAGATTCCGGAAACAAATGCCGATGACCACACGCTATTCAAGCATT
TCATGGCTATTTGTGAACCGGATTATTTCTCCGAACAATCTCCCTACCCTTCCTTTAATGTGCAAGCGGCCAAAGAACTG
GGGTATTACGGATATGACATCAAACCCTTCAAAAAGTATCTGACGATAAAGAGCAGCCGTGACTATCTTCATAAGGTAAT
GTTACCGCCCGAACTGTCAAATCTCAAATTTGACAAGACACTATATAATAAGGTGGTAAAATTCCTGAAAGAGAATGATC
CCGAAATGATCTATATTTATGGCGGCGATGATCCTTGGACAGCTTCGGGTGTCACTTGGCTGAAGAACAAGAAAAACATA
AAAGTTTATGTGTTACCCGGCGGCAGCCATACCACCCGTATCGGCAGCTTTGACACCGACACACAAGAAGAAATCAAGAC
ACAGATCAATGCATGGCTGAATAAAGAATAG

Upstream 100 bases:

>100_bases
CTCAGCTTTATTAAGTAACACAAAGATAAAAGATTACCCGACAATATCGAAATAAAATACTATTTTTGTTGCCCATTAGT
TATTAAACCATTTATAAACG

Downstream 100 bases:

>100_bases
CAAAGAGACGAGATAAAAAGCTTTTCCGCCACAGGTTACGCAGATTGTCACCGGTTATTTCCATTGAGGACCCACTGCTT
AAATTGGACCGATGTCAATC

Product: putative secreted tripeptidyl aminopeptidase

Products: NA

Alternate protein names: PTP-SM; Tripeptidyl aminopeptidase; SM-TAP [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MKHTLSFMVWAILAVLLPLQMAQAAAPPTELQKRLQNLPDISDIKPMQSDAYPEKYVFFINQLLDPHHPEAGNFKQRVIL
SHVGFDRPTVLVTEGYTAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDYLTVENSLYDLHHVTTTLKQLYD
EKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNQSLEDGRHEPFIANKVSTPENRKRVENFQLEVLKRKSRLLPIF
EKYCSDKGYTFRIPIAEVYDFNVLEYSFALWQWGTPVNKIPETNADDHTLFKHFMAICEPDYFSEQSPYPSFNVQAAKEL
GYYGYDIKPFKKYLTIKSSRDYLHKVMLPPELSNLKFDKTLYNKVVKFLKENDPEMIYIYGGDDPWTASGVTWLKNKKNI
KVYVLPGGSHTTRIGSFDTDTQEEIKTQINAWLNKE

Sequences:

>Translated_436_residues
MKHTLSFMVWAILAVLLPLQMAQAAAPPTELQKRLQNLPDISDIKPMQSDAYPEKYVFFINQLLDPHHPEAGNFKQRVIL
SHVGFDRPTVLVTEGYTAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDYLTVENSLYDLHHVTTTLKQLYD
EKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNQSLEDGRHEPFIANKVSTPENRKRVENFQLEVLKRKSRLLPIF
EKYCSDKGYTFRIPIAEVYDFNVLEYSFALWQWGTPVNKIPETNADDHTLFKHFMAICEPDYFSEQSPYPSFNVQAAKEL
GYYGYDIKPFKKYLTIKSSRDYLHKVMLPPELSNLKFDKTLYNKVVKFLKENDPEMIYIYGGDDPWTASGVTWLKNKKNI
KVYVLPGGSHTTRIGSFDTDTQEEIKTQINAWLNKE
>Mature_436_residues
MKHTLSFMVWAILAVLLPLQMAQAAAPPTELQKRLQNLPDISDIKPMQSDAYPEKYVFFINQLLDPHHPEAGNFKQRVIL
SHVGFDRPTVLVTEGYTAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDYLTVENSLYDLHHVTTTLKQLYD
EKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNQSLEDGRHEPFIANKVSTPENRKRVENFQLEVLKRKSRLLPIF
EKYCSDKGYTFRIPIAEVYDFNVLEYSFALWQWGTPVNKIPETNADDHTLFKHFMAICEPDYFSEQSPYPSFNVQAAKEL
GYYGYDIKPFKKYLTIKSSRDYLHKVMLPPELSNLKFDKTLYNKVVKFLKENDPEMIYIYGGDDPWTASGVTWLKNKKNI
KVYVLPGGSHTTRIGSFDTDTQEEIKTQINAWLNKE

Specific function: Has proline-specific tripeptidyl aminopeptidase and tetrapeptidyl aminopeptidase activity. Activity is highest against tripeptides containing an Ala-Pro motif. Involved in the final processing of transglutaminase, by removing either the tetrapeptide Phe-A

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted (PubMed:14519127). Cell surface (PubMed:15598885) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S37 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008761 [H]

Pfam domain/function: PF05576 Peptidase_S37 [H]

EC number: NA

Molecular weight: Translated: 50766; Mature: 50766

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTLSFMVWAILAVLLPLQMAQAAAPPTELQKRLQNLPDISDIKPMQSDAYPEKYVFFI
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
NQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYTAHYATHPRYQEELSKLFNANLVF
HHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHCCCEEE
VEYRYFGESMPKPCNWDYLTVENSLYDLHHVTTTLKQLYDEKWIATGISKGGQTTMFYRT
EEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
YFPDDVDISVPYVAPLNQSLEDGRHEPFIANKVSTPENRKRVENFQLEVLKRKSRLLPIF
ECCCCCCEECCEECCCCCHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
EKYCSDKGYTFRIPIAEVYDFNVLEYSFALWQWGTPVNKIPETNADDHTLFKHFMAICEP
HHHHCCCCCEEEEEHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
DYFSEQSPYPSFNVQAAKELGYYGYDIKPFKKYLTIKSSRDYLHKVMLPPELSNLKFDKT
CCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHEEECCCHHHHHHHCCCCCCCCCCHHHH
LYNKVVKFLKENDPEMIYIYGGDDPWTASGVTWLKNKKNIKVYVLPGGSHTTRIGSFDTD
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEECCCCCC
TQEEIKTQINAWLNKE
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKHTLSFMVWAILAVLLPLQMAQAAAPPTELQKRLQNLPDISDIKPMQSDAYPEKYVFFI
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
NQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYTAHYATHPRYQEELSKLFNANLVF
HHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHCCCEEE
VEYRYFGESMPKPCNWDYLTVENSLYDLHHVTTTLKQLYDEKWIATGISKGGQTTMFYRT
EEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
YFPDDVDISVPYVAPLNQSLEDGRHEPFIANKVSTPENRKRVENFQLEVLKRKSRLLPIF
ECCCCCCEECCEECCCCCHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
EKYCSDKGYTFRIPIAEVYDFNVLEYSFALWQWGTPVNKIPETNADDHTLFKHFMAICEP
HHHHCCCCCEEEEEHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
DYFSEQSPYPSFNVQAAKELGYYGYDIKPFKKYLTIKSSRDYLHKVMLPPELSNLKFDKT
CCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHEEECCCHHHHHHHCCCCCCCCCCHHHH
LYNKVVKFLKENDPEMIYIYGGDDPWTASGVTWLKNKKNIKVYVLPGGSHTTRIGSFDTD
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEECCCCCC
TQEEIKTQINAWLNKE
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA