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The map label for this gene is rnhB

Identifier: 150003938

GI number: 150003938

Start: 1830072

End: 1830677

Strand: Direct

Name: rnhB

Synonym: BVU_1371

Alternate gene names: 150003938

Gene position: 1830072-1830677 (Clockwise)

Preceding gene: 150003929

Following gene: 150003942

Centisome position: 35.44

GC content: 40.1

Gene sequence:

>606_bases
ATGTTATTACCTTATTTGAATAAAGATCTGATAGAGGCCGGTTGTGATGAGGCGGGCAGGGGATGTCTGGCAGGATCTGT
ATATGCAGCAGCTGTTATTTTACCTGTAGATTTTAAGAATGAATTGCTGAATGATTCCAAGCAACTGACGGAGCATCAGC
GTTATGCGCTGCGAGAGATTGTGGAAAGAGAAGCATTGGCATGGGCTGTAGGTGTAGTGACTCCTGAAGAGATAGACGAG
ATAAATATCCTTAATGCGTCTTTTCTGGCAATGCATCGTGCTGTGGATCAATTGAAAATTCGTCCCCAACATTTGTTGAT
TGATGGGAATCGTTTTAAAAAGTATCAGGATTTGCCGCATACTACTGTGGTAAAAGGAGATGGAAAATATCTTTCTATTG
CCGCTGCATCTATTCTGGCGAAAACCTATCGTGATGATTATATGAATGAACTGCATAAAGAATATCCTTTTTATGATTGG
AATAGTAATAAAGGTTATCCTACTAAAAAGCATCGTGCGGCTATCCGTGAACATGGAACAACGCCATATCATCGGATGAC
TTTTAATTTGTTGGGAACAGATCCCCAATTAGAGATTCCTTTCTAA

Upstream 100 bases:

>100_bases
ATCAAGCGTATTTTTGCAAAAATAGTGATTTTCTTTGTAAAAAGACACTCTTGTTTCTCTTTTAAAAGAATATCTTTGCA
AGCAACAATAAAGATGAGCT

Downstream 100 bases:

>100_bases
TTTGAAGAATATATAGGAGGATGGGATAACTTCTTTACATTTCATTCTACTTGGTTGAAAATAAAGCGAAGAATCTGTTT
GATTCATATGAGTCGTAACA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MLLPYLNKDLIEAGCDEAGRGCLAGSVYAAAVILPVDFKNELLNDSKQLTEHQRYALREIVEREALAWAVGVVTPEEIDE
INILNASFLAMHRAVDQLKIRPQHLLIDGNRFKKYQDLPHTTVVKGDGKYLSIAAASILAKTYRDDYMNELHKEYPFYDW
NSNKGYPTKKHRAAIREHGTTPYHRMTFNLLGTDPQLEIPF

Sequences:

>Translated_201_residues
MLLPYLNKDLIEAGCDEAGRGCLAGSVYAAAVILPVDFKNELLNDSKQLTEHQRYALREIVEREALAWAVGVVTPEEIDE
INILNASFLAMHRAVDQLKIRPQHLLIDGNRFKKYQDLPHTTVVKGDGKYLSIAAASILAKTYRDDYMNELHKEYPFYDW
NSNKGYPTKKHRAAIREHGTTPYHRMTFNLLGTDPQLEIPF
>Mature_201_residues
MLLPYLNKDLIEAGCDEAGRGCLAGSVYAAAVILPVDFKNELLNDSKQLTEHQRYALREIVEREALAWAVGVVTPEEIDE
INILNASFLAMHRAVDQLKIRPQHLLIDGNRFKKYQDLPHTTVVKGDGKYLSIAAASILAKTYRDDYMNELHKEYPFYDW
NSNKGYPTKKHRAAIREHGTTPYHRMTFNLLGTDPQLEIPF

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=177, Percent_Identity=49.7175141242938, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_BACV8 (A6L046)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298682.1
- ProteinModelPortal:   A6L046
- SMR:   A6L046
- STRING:   A6L046
- GeneID:   5302337
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1371
- NMPDR:   fig|435590.6.peg.1292
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 22929; Mature: 22929

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPYLNKDLIEAGCDEAGRGCLAGSVYAAAVILPVDFKNELLNDSKQLTEHQRYALREI
CCCCCCCHHHHHHCCCCCCCCCHHHHHEEEEEEEECCHHHHHHCCHHHHHHHHHHHHHHH
VEREALAWAVGVVTPEEIDEINILNASFLAMHRAVDQLKIRPQHLLIDGNRFKKYQDLPH
HHHHHHHHHHCCCCHHHHCCEEECHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCC
TTVVKGDGKYLSIAAASILAKTYRDDYMNELHKEYPFYDWNSNKGYPTKKHRAAIREHGT
CEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCC
TPYHRMTFNLLGTDPQLEIPF
CCHHEEEEEEECCCCCEECCC
>Mature Secondary Structure
MLLPYLNKDLIEAGCDEAGRGCLAGSVYAAAVILPVDFKNELLNDSKQLTEHQRYALREI
CCCCCCCHHHHHHCCCCCCCCCHHHHHEEEEEEEECCHHHHHHCCHHHHHHHHHHHHHHH
VEREALAWAVGVVTPEEIDEINILNASFLAMHRAVDQLKIRPQHLLIDGNRFKKYQDLPH
HHHHHHHHHHCCCCHHHHCCEEECHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCC
TTVVKGDGKYLSIAAASILAKTYRDDYMNELHKEYPFYDWNSNKGYPTKKHRAAIREHGT
CEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCC
TPYHRMTFNLLGTDPQLEIPF
CCHHEEEEEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA