Click here to switch to the map view.

The map label for this gene is fucO [H]

Identifier: 150003819

GI number: 150003819

Start: 1678581

End: 1679735

Strand: Direct

Name: fucO [H]

Synonym: BVU_1251

Alternate gene names: 150003819

Gene position: 1678581-1679735 (Clockwise)

Preceding gene: 150003818

Following gene: 150003820

Centisome position: 32.51

GC content: 48.57

Gene sequence:

>1155_bases
ATGATTAACAGATTTGTATTGAACGAAGTATCTTACTTCGGTCCGGGTGCGCGTGAAGTGCTTCCACAAGAGATTAAACG
TTTGGGCTTGCATAAGGCGTTTGTTGCTACAGACAAGGACTTGATTAAGTTCGGTGTGGCTGATAAAGTGTTGAAAGTCT
TGGAGAATGCAGGTATTCCTTATGAAATATTCAGTGAAATCAAACCGAATCCTACTGTAAGCAATGTAAAGGCGGGAGTT
GAAGCTTTTGCAAAATCAGGAGCGGACTTTATTCTGGCTATCGGCGGCGGTTCGTCTATCGATACTTCGAAAGCGATTGG
TATCATCACTAATAATCCAGACTTCAGTGATGTGGTGTCACTGGAAGGTGTGGCTCCTACAAGGAAAAAGTCAGTGCCTA
TCATTGCACTGCCCACTACCGCCGGTACTGCCGCCGAGGTGACTATCAACTATGTCATCACGGATGAGGAAAACCATAAG
AAGATGGTTTGTGTAGACCCGAACGATATCCCCGCCATCGCTATTGTGGATGCGGAACTGATGTACACTCTGCCTAAAGG
GCTGACTGCTTCTACCGGTTTGGACGCACTGACCCACGCCATCGAAGGGTTGATAACCAAAGGCGCTTGGGAAATGAGTG
ATATGTTCGAGATCAAGGCGATCGAAATGATTGCCCGTTATCTGGAAACCGCTGTCTTCGAGCCTACCAATGCGGAAGCC
CGTAACGGTATGGCTGTGGCACAGTACATTGCAGGTATGGCGTTCTCTAATGTAGGCTTGGGCGTGGTTCACGGTATGGC
TCATCCGTTGGGAGCTATCTTCGATATTCCTCACGGTGTGGCTAATGCACTGTTGCTGCCTGTCATCATGGAGTTCAATG
CTCCGGCTGCTTTGTCCAAATATGTAGATATCGCCAAGGCGATGAATGTGTACAAGGATGGCATGAGCCGGGAAGAGGCT
GCGAAGGCTGCTGTTGAGGCGGTGAAGGCATTGTCTGTCAAGGTGGGTATCCCTCAGCATTTGTCTGAACTGGGTATTAA
GGAAGAAGACTTGCCCCGTCTGGCCGCTTCGGCTATTGCCGATGTGTGTACGCCGGGCAATCCTCGTGAAGTGACGGAAG
AAATTATTCTGGAACTTTACAAGAAGGCTTTCTAA

Upstream 100 bases:

>100_bases
GCATGAATGCCAAAAAACATACTATAAGAATCTTTTTAAAGAGCCGTTTTCTCAAGAATTTGTACTAAGTTTGCAACCAA
ACTACATAATTAAAAAAACT

Downstream 100 bases:

>100_bases
GCGTAATTCTTTTGTAATAAAAGCATAGGTGGTGTGTGGATGTGCAGGGCATATCCACACACTTTTTTTATCTCCTTTCT
GTTTTTTGAATTGTTATGTG

Product: L-1,2-propanediol oxidoreductase

Products: NA

Alternate protein names: Propanediol oxidoreductase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MINRFVLNEVSYFGPGAREVLPQEIKRLGLHKAFVATDKDLIKFGVADKVLKVLENAGIPYEIFSEIKPNPTVSNVKAGV
EAFAKSGADFILAIGGGSSIDTSKAIGIITNNPDFSDVVSLEGVAPTRKKSVPIIALPTTAGTAAEVTINYVITDEENHK
KMVCVDPNDIPAIAIVDAELMYTLPKGLTASTGLDALTHAIEGLITKGAWEMSDMFEIKAIEMIARYLETAVFEPTNAEA
RNGMAVAQYIAGMAFSNVGLGVVHGMAHPLGAIFDIPHGVANALLLPVIMEFNAPAALSKYVDIAKAMNVYKDGMSREEA
AKAAVEAVKALSVKVGIPQHLSELGIKEEDLPRLAASAIADVCTPGNPREVTEEIILELYKKAF

Sequences:

>Translated_384_residues
MINRFVLNEVSYFGPGAREVLPQEIKRLGLHKAFVATDKDLIKFGVADKVLKVLENAGIPYEIFSEIKPNPTVSNVKAGV
EAFAKSGADFILAIGGGSSIDTSKAIGIITNNPDFSDVVSLEGVAPTRKKSVPIIALPTTAGTAAEVTINYVITDEENHK
KMVCVDPNDIPAIAIVDAELMYTLPKGLTASTGLDALTHAIEGLITKGAWEMSDMFEIKAIEMIARYLETAVFEPTNAEA
RNGMAVAQYIAGMAFSNVGLGVVHGMAHPLGAIFDIPHGVANALLLPVIMEFNAPAALSKYVDIAKAMNVYKDGMSREEA
AKAAVEAVKALSVKVGIPQHLSELGIKEEDLPRLAASAIADVCTPGNPREVTEEIILELYKKAF
>Mature_384_residues
MINRFVLNEVSYFGPGAREVLPQEIKRLGLHKAFVATDKDLIKFGVADKVLKVLENAGIPYEIFSEIKPNPTVSNVKAGV
EAFAKSGADFILAIGGGSSIDTSKAIGIITNNPDFSDVVSLEGVAPTRKKSVPIIALPTTAGTAAEVTINYVITDEENHK
KMVCVDPNDIPAIAIVDAELMYTLPKGLTASTGLDALTHAIEGLITKGAWEMSDMFEIKAIEMIARYLETAVFEPTNAEA
RNGMAVAQYIAGMAFSNVGLGVVHGMAHPLGAIFDIPHGVANALLLPVIMEFNAPAALSKYVDIAKAMNVYKDGMSREEA
AKAAVEAVKALSVKVGIPQHLSELGIKEEDLPRLAASAIADVCTPGNPREVTEEIILELYKKAF

Specific function: Fucose metabolism; fourth step. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=380, Percent_Identity=26.0526315789474, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1789163, Length=384, Percent_Identity=57.8125, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI48994951, Length=356, Percent_Identity=42.6966292134831, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI87082107, Length=382, Percent_Identity=35.6020942408377, Blast_Score=224, Evalue=6e-60,
Organism=Escherichia coli, GI1787493, Length=402, Percent_Identity=33.5820895522388, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI1789386, Length=398, Percent_Identity=25.8793969849246, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17537053, Length=421, Percent_Identity=28.5035629453682, Blast_Score=156, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321181, Length=382, Percent_Identity=37.434554973822, Blast_Score=260, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24657991, Length=409, Percent_Identity=28.1173594132029, Blast_Score=158, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR013460 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.77 [H]

Molecular weight: Translated: 40916; Mature: 40916

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINRFVLNEVSYFGPGAREVLPQEIKRLGLHKAFVATDKDLIKFGVADKVLKVLENAGIP
CCCHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
YEIFSEIKPNPTVSNVKAGVEAFAKSGADFILAIGGGSSIDTSKAIGIITNNPDFSDVVS
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHC
LEGVAPTRKKSVPIIALPTTAGTAAEVTINYVITDEENHKKMVCVDPNDIPAIAIVDAEL
CCCCCCCCCCCCCEEEECCCCCCEEEEEEEEEEECCCCCCEEEEECCCCCCEEEEECHHH
MYTLPKGLTASTGLDALTHAIEGLITKGAWEMSDMFEIKAIEMIARYLETAVFEPTNAEA
HHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RNGMAVAQYIAGMAFSNVGLGVVHGMAHPLGAIFDIPHGVANALLLPVIMEFNAPAALSK
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
YVDIAKAMNVYKDGMSREEAAKAAVEAVKALSVKVGIPQHLSELGIKEEDLPRLAASAIA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHH
DVCTPGNPREVTEEIILELYKKAF
HHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MINRFVLNEVSYFGPGAREVLPQEIKRLGLHKAFVATDKDLIKFGVADKVLKVLENAGIP
CCCHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
YEIFSEIKPNPTVSNVKAGVEAFAKSGADFILAIGGGSSIDTSKAIGIITNNPDFSDVVS
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHC
LEGVAPTRKKSVPIIALPTTAGTAAEVTINYVITDEENHKKMVCVDPNDIPAIAIVDAEL
CCCCCCCCCCCCCEEEECCCCCCEEEEEEEEEEECCCCCCEEEEECCCCCCEEEEECHHH
MYTLPKGLTASTGLDALTHAIEGLITKGAWEMSDMFEIKAIEMIARYLETAVFEPTNAEA
HHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RNGMAVAQYIAGMAFSNVGLGVVHGMAHPLGAIFDIPHGVANALLLPVIMEFNAPAALSK
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
YVDIAKAMNVYKDGMSREEAAKAAVEAVKALSVKVGIPQHLSELGIKEEDLPRLAASAIA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHH
DVCTPGNPREVTEEIILELYKKAF
HHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]