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The map label for this gene is engD [H]

Identifier: 150003773

GI number: 150003773

Start: 1623158

End: 1624261

Strand: Reverse

Name: engD [H]

Synonym: BVU_1205

Alternate gene names: 150003773

Gene position: 1624261-1623158 (Counterclockwise)

Preceding gene: 150003774

Following gene: 150003772

Centisome position: 31.46

GC content: 44.84

Gene sequence:

>1104_bases
ATGGCTTTACAATGTGGTATTGTCGGTCTTCCAAACGTAGGAAAGTCGACACTTTTTAATTGTTTATCGAATGCAAAGGC
TCAAGCAGCCAACTTCCCTTTCTGTACCATCGAACCGAATGTAGGTGTCATCACCGTTCCTGATGAACGCCTGACCAAAC
TTGCCGAACTGGTTCATCCGGGACGTATCGTTCCCACTACTGTAGAAATTGTTGACATTGCAGGACTTGTAAAAGGGGCT
AGCAAAGGTGAAGGGCTGGGAAACAAGTTTCTGGCAAATATCCGTGAAACAGATGCTATCCTGCACGTACTCCGTTGTTT
TGACGATGAAAATGTAACTCATGTAGACGGTAGTGTAGATCCGGTACGTGACAAAGAAATCATTGACACCGAACTCCAGC
TGAAAGATTTAGAAACCATTGAAAGCCGTATTCAAAAAGTACAAAAACAGGCACAGACGGGCGGTGACAAACAAGCAAAA
CAAATGTACGACATCCTTGTTAAATATAAAGACGCATTGGAACAAGGCAAATCTGCGCGTACCGTACAATTTGACAGCAA
AGACGAACAAAAAATCGCAAAAGAACTGTTCTTGCTGACCAGCAAACCAGTGATGTACGTATGCAACGTGGACGAAGCAA
GTGCTGCTACCGGCAATAAATATGTAGAACAAGTACGCGAAGCCGTAAAAGAAGAAAATGCAGAAATTCTGGTCGTAGCC
GCCAAAACCGAAGCCGATATCGCAGAACTTGAAACCTATGAAGACCGCCAGATGTTCCTTCAGGAAGTCGGTCTGAAAGA
ATCAGGTGTAAACCGTCTGATCAAATCGGCTTATCACCTGCTGGAACTGGAAACCTTCATCACCGCCGGAGAAATGGAAG
TAAAAGCCTGGACCTATCGTAAAGGATGGAAAGCCCCCCAATGTGCAGGAGTCATCCACACCGATTTCGAGAAAGGATTT
ATCCGTGCCGAGGTAATCAAGTACGAAGACTACATTAAATATGGTTCGGAAGCCGCCGTGAAAGAGGCTGGAAAAATGGG
CGTGGAAGGTAAAGAATACGTAGTACAGGACGGTGACATCATGCACTTCCGTTTCAATGTATAA

Upstream 100 bases:

>100_bases
TAAAAAAGCCAAATCTGACTTCAATATGAAGTCTGATACAAAAAGAATGGTTATCTTTGCAAACAAATAGATAGATAATA
ATCAAAAAAACAAATAGATA

Downstream 100 bases:

>100_bases
GGTAAATCAAAACGCAAAAGACTTGTCATGCAATGCATGAAAAAACATCAGGAAACCAGCAAAACTGATGGCAGACCGAT
AAGTCAGTGTTTTGTTTCCT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MALQCGIVGLPNVGKSTLFNCLSNAKAQAANFPFCTIEPNVGVITVPDERLTKLAELVHPGRIVPTTVEIVDIAGLVKGA
SKGEGLGNKFLANIRETDAILHVLRCFDDENVTHVDGSVDPVRDKEIIDTELQLKDLETIESRIQKVQKQAQTGGDKQAK
QMYDILVKYKDALEQGKSARTVQFDSKDEQKIAKELFLLTSKPVMYVCNVDEASAATGNKYVEQVREAVKEENAEILVVA
AKTEADIAELETYEDRQMFLQEVGLKESGVNRLIKSAYHLLELETFITAGEMEVKAWTYRKGWKAPQCAGVIHTDFEKGF
IRAEVIKYEDYIKYGSEAAVKEAGKMGVEGKEYVVQDGDIMHFRFNV

Sequences:

>Translated_367_residues
MALQCGIVGLPNVGKSTLFNCLSNAKAQAANFPFCTIEPNVGVITVPDERLTKLAELVHPGRIVPTTVEIVDIAGLVKGA
SKGEGLGNKFLANIRETDAILHVLRCFDDENVTHVDGSVDPVRDKEIIDTELQLKDLETIESRIQKVQKQAQTGGDKQAK
QMYDILVKYKDALEQGKSARTVQFDSKDEQKIAKELFLLTSKPVMYVCNVDEASAATGNKYVEQVREAVKEENAEILVVA
AKTEADIAELETYEDRQMFLQEVGLKESGVNRLIKSAYHLLELETFITAGEMEVKAWTYRKGWKAPQCAGVIHTDFEKGF
IRAEVIKYEDYIKYGSEAAVKEAGKMGVEGKEYVVQDGDIMHFRFNV
>Mature_366_residues
ALQCGIVGLPNVGKSTLFNCLSNAKAQAANFPFCTIEPNVGVITVPDERLTKLAELVHPGRIVPTTVEIVDIAGLVKGAS
KGEGLGNKFLANIRETDAILHVLRCFDDENVTHVDGSVDPVRDKEIIDTELQLKDLETIESRIQKVQKQAQTGGDKQAKQ
MYDILVKYKDALEQGKSARTVQFDSKDEQKIAKELFLLTSKPVMYVCNVDEASAATGNKYVEQVREAVKEENAEILVVAA
KTEADIAELETYEDRQMFLQEVGLKESGVNRLIKSAYHLLELETFITAGEMEVKAWTYRKGWKAPQCAGVIHTDFEKGFI
RAEVIKYEDYIKYGSEAAVKEAGKMGVEGKEYVVQDGDIMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=371, Percent_Identity=49.5956873315364, Blast_Score=344, Evalue=7e-95,
Organism=Homo sapiens, GI58761502, Length=229, Percent_Identity=44.9781659388646, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI24308117, Length=148, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI111955139, Length=99, Percent_Identity=34.3434343434343, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787454, Length=367, Percent_Identity=56.6757493188011, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=32.8125, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=45.9016393442623, Blast_Score=322, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=41.5549597855228, Blast_Score=270, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6321773, Length=382, Percent_Identity=36.6492146596859, Blast_Score=221, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6321649, Length=145, Percent_Identity=40, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6321962, Length=129, Percent_Identity=29.4573643410853, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=47.554347826087, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=47.554347826087, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=47.554347826087, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=45.565749235474, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24585318, Length=102, Percent_Identity=36.2745098039216, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40800; Mature: 40669

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQCGIVGLPNVGKSTLFNCLSNAKAQAANFPFCTIEPNVGVITVPDERLTKLAELVHP
CCEEECCCCCCCCCHHHHHHHHHCCCHHHCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
GRIVPTTVEIVDIAGLVKGASKGEGLGNKFLANIRETDAILHVLRCFDDENVTHVDGSVD
CCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PVRDKEIIDTELQLKDLETIESRIQKVQKQAQTGGDKQAKQMYDILVKYKDALEQGKSAR
CCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
TVQFDSKDEQKIAKELFLLTSKPVMYVCNVDEASAATGNKYVEQVREAVKEENAEILVVA
EEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCHHHHHHHHHHHHHCCCCEEEEE
AKTEADIAELETYEDRQMFLQEVGLKESGVNRLIKSAYHLLELETFITAGEMEVKAWTYR
ECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KGWKAPQCAGVIHTDFEKGFIRAEVIKYEDYIKYGSEAAVKEAGKMGVEGKEYVVQDGDI
CCCCCCCCCCCEECCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCE
MHFRFNV
EEEEECC
>Mature Secondary Structure 
ALQCGIVGLPNVGKSTLFNCLSNAKAQAANFPFCTIEPNVGVITVPDERLTKLAELVHP
CEEECCCCCCCCCHHHHHHHHHCCCHHHCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
GRIVPTTVEIVDIAGLVKGASKGEGLGNKFLANIRETDAILHVLRCFDDENVTHVDGSVD
CCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PVRDKEIIDTELQLKDLETIESRIQKVQKQAQTGGDKQAKQMYDILVKYKDALEQGKSAR
CCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
TVQFDSKDEQKIAKELFLLTSKPVMYVCNVDEASAATGNKYVEQVREAVKEENAEILVVA
EEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCHHHHHHHHHHHHHCCCCEEEEE
AKTEADIAELETYEDRQMFLQEVGLKESGVNRLIKSAYHLLELETFITAGEMEVKAWTYR
ECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KGWKAPQCAGVIHTDFEKGFIRAEVIKYEDYIKYGSEAAVKEAGKMGVEGKEYVVQDGDI
CCCCCCCCCCCEECCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCE
MHFRFNV
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]