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The map label for this gene is uppP

Identifier: 150003740

GI number: 150003740

Start: 1585657

End: 1586457

Strand: Direct

Name: uppP

Synonym: BVU_1171

Alternate gene names: 150003740

Gene position: 1585657-1586457 (Clockwise)

Preceding gene: 150003739

Following gene: 150003741

Centisome position: 30.71

GC content: 43.07

Gene sequence:

>801_bases
ATGGAATGGTTTGAGGCATTGATCCTTGGTGTGCTCCAAGGATTGACAGAGTATTTGCCGGTCAGCAGTAGTGGTCATCT
GGCTATCGGTTCGGCATTGTTTGGCATACAAGGGGAAGATAATCTGACTTTTACCATAGCAGTGCATGTGGCTACGGTAC
TCAGTACTTTGGTTATATTATGGAAAGAAATAGGCTGGATATTCCGTGGCTTGTTCAAGTTTGAGATGAATGCGGAGACA
AAATATGTGATCAATATCCTGGTATCCATGATTCCTATCGGCATTGTGGGTGTGTTTTTTAAAGATTATGTGGAAGAAAT
TTTCGGTTCCGGCTTGCTCATTGTAGGTTGTATGCTGTTATTGACAGCTTTGCTTCTTGCTTTCTCTTATTATGCAAAAC
CTCGTTTGAAAGAGAACATCAGCATGAAGGATGCGTTTATTATAGGTCTGGCACAGGCTTGTGCCGTGATGCCGGGATTA
TCCCGTTCGGGTACTACCATTGCTACCGGTTTGTTGTTGGGAGATAACAAGGCGAAACTGGCTCAGTTCTCTTTCCTGAT
GGTGATTCCTCCTATATTGGGTGAGGCGTTGCTGGATGGTATGAAGATTGTAAAAGGAGCTGCAGCCGGCACATCAGATA
TATCTGTATTGTCATTGGTTGTAGGTTTTCTGGCAGCTTTCATATCGGGCTGTGTAGCTTGTAAGTGGATGATTAATATT
GTGAAGAAAGGTAAGTTGATTTATTTTGCTATCTATTGTGCCATAGCCGGTGCCGTTACGATAGCGTGCACATTGATGTA
A

Upstream 100 bases:

>100_bases
ATCTTTATGATTTATGGCATTGTCCGCAAGCCAAAGGACAAGACAGAAGTGGTTAACTCTTGATTTTTTTAATTTTTAAT
TCTCAATTTTTATTTAAAGA

Downstream 100 bases:

>100_bases
TTGGATGAATTTTAAAGAAGGAGAAGTATTATACTTTGATAAACCGCTGAAATGGACCTCATTTGCAGTGGTGAACAAGA
TAAGATACCATATTTGCCGC

Product: putative undecaprenol kinase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MEWFEALILGVLQGLTEYLPVSSSGHLAIGSALFGIQGEDNLTFTIAVHVATVLSTLVILWKEIGWIFRGLFKFEMNAET
KYVINILVSMIPIGIVGVFFKDYVEEIFGSGLLIVGCMLLLTALLLAFSYYAKPRLKENISMKDAFIIGLAQACAVMPGL
SRSGTTIATGLLLGDNKAKLAQFSFLMVIPPILGEALLDGMKIVKGAAAGTSDISVLSLVVGFLAAFISGCVACKWMINI
VKKGKLIYFAIYCAIAGAVTIACTLM

Sequences:

>Translated_266_residues
MEWFEALILGVLQGLTEYLPVSSSGHLAIGSALFGIQGEDNLTFTIAVHVATVLSTLVILWKEIGWIFRGLFKFEMNAET
KYVINILVSMIPIGIVGVFFKDYVEEIFGSGLLIVGCMLLLTALLLAFSYYAKPRLKENISMKDAFIIGLAQACAVMPGL
SRSGTTIATGLLLGDNKAKLAQFSFLMVIPPILGEALLDGMKIVKGAAAGTSDISVLSLVVGFLAAFISGCVACKWMINI
VKKGKLIYFAIYCAIAGAVTIACTLM
>Mature_266_residues
MEWFEALILGVLQGLTEYLPVSSSGHLAIGSALFGIQGEDNLTFTIAVHVATVLSTLVILWKEIGWIFRGLFKFEMNAET
KYVINILVSMIPIGIVGVFFKDYVEEIFGSGLLIVGCMLLLTALLLAFSYYAKPRLKENISMKDAFIIGLAQACAVMPGL
SRSGTTIATGLLLGDNKAKLAQFSFLMVIPPILGEALLDGMKIVKGAAAGTSDISVLSLVVGFLAAFISGCVACKWMINI
VKKGKLIYFAIYCAIAGAVTIACTLM

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=262, Percent_Identity=35.1145038167939, Blast_Score=141, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_BACV8 (A6KZJ8)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298484.1
- STRING:   A6KZJ8
- GeneID:   5302137
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1171
- NMPDR:   fig|435590.6.peg.1109
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- ProtClustDB:   CLSK823439
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28479; Mature: 28479

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0x1af14f4c)-; HASH(0x1bb69070)-; HASH(0x1bb6e7e8)-; HASH(0x1b4d3728)-; HASH(0x1ba18f4c)-; HASH(0x1b23ec0c)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWFEALILGVLQGLTEYLPVSSSGHLAIGSALFGIQGEDNLTFTIAVHVATVLSTLVIL
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHEECCCCCCCEEEEHHHHHHHHHHHHHHH
WKEIGWIFRGLFKFEMNAETKYVINILVSMIPIGIVGVFFKDYVEEIFGSGLLIVGCMLL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LTALLLAFSYYAKPRLKENISMKDAFIIGLAQACAVMPGLSRSGTTIATGLLLGDNKAKL
HHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEECCCCHHH
AQFSFLMVIPPILGEALLDGMKIVKGAAAGTSDISVLSLVVGFLAAFISGCVACKWMINI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKKGKLIYFAIYCAIAGAVTIACTLM
HHCCCHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MEWFEALILGVLQGLTEYLPVSSSGHLAIGSALFGIQGEDNLTFTIAVHVATVLSTLVIL
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHEECCCCCCCEEEEHHHHHHHHHHHHHHH
WKEIGWIFRGLFKFEMNAETKYVINILVSMIPIGIVGVFFKDYVEEIFGSGLLIVGCMLL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LTALLLAFSYYAKPRLKENISMKDAFIIGLAQACAVMPGLSRSGTTIATGLLLGDNKAKL
HHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEECCCCHHH
AQFSFLMVIPPILGEALLDGMKIVKGAAAGTSDISVLSLVVGFLAAFISGCVACKWMINI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKKGKLIYFAIYCAIAGAVTIACTLM
HHCCCHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA