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The map label for this gene is nadA [H]

Identifier: 150003714

GI number: 150003714

Start: 1542417

End: 1543409

Strand: Direct

Name: nadA [H]

Synonym: BVU_1145

Alternate gene names: 150003714

Gene position: 1542417-1543409 (Clockwise)

Preceding gene: 150003713

Following gene: 150003716

Centisome position: 29.87

GC content: 44.01

Gene sequence:

>993_bases
ATGAATAAAGAGGAATGGTTGAAAAAAGGGTATGTTACCGAACCGGTAGACAAAACTCTGGATTTGAAAACTGAAATTGA
TAAGTTGCGTAAGGAAAAGAATGCGCTTATCCTAGGTCACTATTACCAGTCGGGCGAAATACAAGATATTGCCGACTTTG
TAGGTGACAGCTTGGCGCTGGCACAATGGGCGGCTAAAACGGATGCGGATATCATTGTGATGTGTGGTGTCCACTTTATG
GGTGAAACGGCTAAGATTCTTTGTCCTGATAAAAAAGTGCTGGTACCGGATTTGAATGCAGGCTGTTCATTGGCCGACAG
TTGTCCTGCTGATGAGTTTGCTAAATTTGTCCAAGAGCATCCGGATTATACAGTGATTTCGTATGTTAACACTACAGCGG
CTGTTAAAGCGGTGACCGATGTGGTGGTCACTTCTACTAATGCCAAGCAGATCGTAGAAAGTTTTCCGGCAGATGAAAAG
ATTATTTTCGGTCCGGATAGAAATTTGGGTAATTATATCAATTCGATTACAGGACGCAATATGTTGCTTTGGGATGGTGC
CTGCCATGTGCACGAACAGTTCTCTGTGGAGAAAATACTGGAGTTGAAAAAACAGTATCCTGACGCTGCTGTTCTGGTTC
ATCCCGAATGTAAAGGAGCCGTTTCCAAACTGGCCGACAAGGTTGCTTCTACGGCAGGATTGTTGAAATATGCCATTGCC
AGTGACAAAAAAGACTTTATTGTGGCTACAGAAAGCGGTATTTTGCACGAGATGCGTAAGAAATGTCCTGAGAAGAACTT
TATTCCCGCTCCTCCCGAAGACAGTACCTGCGCTTGCAATGAATGTAATTTCATGCGTCTGAATACGCTGGAGAAGCTGT
ACAATACGTTAAAGTATGAATGGCCGGAAGTGACAGTGGATGAAGCGGTAGCTGAGGAGGCAGTGAAACCTATCAAGAAG
ATGCTGGAAATTTCGGAGAAGCTGGGATTATGA

Upstream 100 bases:

>100_bases
AATCACTATTTTGGGTGGTCATAACCATAAAGTTTTTAACTTTGCATATTATCAATACCATATTTCTTTTTTTGAAAGAA
GGAGAAAAAATATAGATATA

Downstream 100 bases:

>100_bases
CTTTTGTAAAAGATAACAAGATGTGGTTAATAAAAGACGTTTCTGTTATTCTTAAAAGTAAAGGGGAATTCTTCTGGAAA
GGATTTATCATCGGAATAGG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNKEEWLKKGYVTEPVDKTLDLKTEIDKLRKEKNALILGHYYQSGEIQDIADFVGDSLALAQWAAKTDADIIVMCGVHFM
GETAKILCPDKKVLVPDLNAGCSLADSCPADEFAKFVQEHPDYTVISYVNTTAAVKAVTDVVVTSTNAKQIVESFPADEK
IIFGPDRNLGNYINSITGRNMLLWDGACHVHEQFSVEKILELKKQYPDAAVLVHPECKGAVSKLADKVASTAGLLKYAIA
SDKKDFIVATESGILHEMRKKCPEKNFIPAPPEDSTCACNECNFMRLNTLEKLYNTLKYEWPEVTVDEAVAEEAVKPIKK
MLEISEKLGL

Sequences:

>Translated_330_residues
MNKEEWLKKGYVTEPVDKTLDLKTEIDKLRKEKNALILGHYYQSGEIQDIADFVGDSLALAQWAAKTDADIIVMCGVHFM
GETAKILCPDKKVLVPDLNAGCSLADSCPADEFAKFVQEHPDYTVISYVNTTAAVKAVTDVVVTSTNAKQIVESFPADEK
IIFGPDRNLGNYINSITGRNMLLWDGACHVHEQFSVEKILELKKQYPDAAVLVHPECKGAVSKLADKVASTAGLLKYAIA
SDKKDFIVATESGILHEMRKKCPEKNFIPAPPEDSTCACNECNFMRLNTLEKLYNTLKYEWPEVTVDEAVAEEAVKPIKK
MLEISEKLGL
>Mature_330_residues
MNKEEWLKKGYVTEPVDKTLDLKTEIDKLRKEKNALILGHYYQSGEIQDIADFVGDSLALAQWAAKTDADIIVMCGVHFM
GETAKILCPDKKVLVPDLNAGCSLADSCPADEFAKFVQEHPDYTVISYVNTTAAVKAVTDVVVTSTNAKQIVESFPADEK
IIFGPDRNLGNYINSITGRNMLLWDGACHVHEQFSVEKILELKKQYPDAAVLVHPECKGAVSKLADKVASTAGLLKYAIA
SDKKDFIVATESGILHEMRKKCPEKNFIPAPPEDSTCACNECNFMRLNTLEKLYNTLKYEWPEVTVDEAVAEEAVKPIKK
MLEISEKLGL

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=323, Percent_Identity=42.1052631578947, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36606; Mature: 36606

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEEWLKKGYVTEPVDKTLDLKTEIDKLRKEKNALILGHYYQSGEIQDIADFVGDSLAL
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCHHHH
AQWAAKTDADIIVMCGVHFMGETAKILCPDKKVLVPDLNAGCSLADSCPADEFAKFVQEH
HHHHHCCCCCEEEEECCHHCCCCCEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHC
PDYTVISYVNTTAAVKAVTDVVVTSTNAKQIVESFPADEKIIFGPDRNLGNYINSITGRN
CCEEEEEEHHHHHHHHHHHHHHEECCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCE
MLLWDGACHVHEQFSVEKILELKKQYPDAAVLVHPECKGAVSKLADKVASTAGLLKYAIA
EEEECCCHHHHHHCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SDKKDFIVATESGILHEMRKKCPEKNFIPAPPEDSTCACNECNFMRLNTLEKLYNTLKYE
CCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
WPEVTVDEAVAEEAVKPIKKMLEISEKLGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKEEWLKKGYVTEPVDKTLDLKTEIDKLRKEKNALILGHYYQSGEIQDIADFVGDSLAL
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCHHHH
AQWAAKTDADIIVMCGVHFMGETAKILCPDKKVLVPDLNAGCSLADSCPADEFAKFVQEH
HHHHHCCCCCEEEEECCHHCCCCCEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHC
PDYTVISYVNTTAAVKAVTDVVVTSTNAKQIVESFPADEKIIFGPDRNLGNYINSITGRN
CCEEEEEEHHHHHHHHHHHHHHEECCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCE
MLLWDGACHVHEQFSVEKILELKKQYPDAAVLVHPECKGAVSKLADKVASTAGLLKYAIA
EEEECCCHHHHHHCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SDKKDFIVATESGILHEMRKKCPEKNFIPAPPEDSTCACNECNFMRLNTLEKLYNTLKYE
CCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
WPEVTVDEAVAEEAVKPIKKMLEISEKLGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA