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The map label for this gene is fabF [H]

Identifier: 150003619

GI number: 150003619

Start: 1398521

End: 1399786

Strand: Reverse

Name: fabF [H]

Synonym: BVU_1050

Alternate gene names: 150003619

Gene position: 1399786-1398521 (Counterclockwise)

Preceding gene: 150003620

Following gene: 150003618

Centisome position: 27.11

GC content: 42.81

Gene sequence:

>1266_bases
ATGGAATTAAAAAGAGTAGTAGTAACAGGTCTTGGTGCTCTTACTCCTGTAGGTAACAATGTTGCAGAAACATGGGAAAA
CCTGGTGAAGGGGGTAAGCGGGGCAGGACCTATTACTCATTTCGATGCGTCTAAATTCAAGACTCATTTTGCATGCGAAG
TGAAGAATTTCAATGGAACTGATTACATTGACCGTAAAGAACTTCGCAAAATGGATCTGTATACACAGTATGCCATTGCA
GCTGCTAAAGAAGCGGTGGAGGATTCTGGAATGGACCTCGAAAAAGAAGATTTGAATAGAATAGGTGTAATTTACGGTGT
AGGTATCGGAGGTATTCATACTTTTGAAGAGGAAGTAGCTAATTATACACTGAATAAAGATACTGTCGGACCGAAATTCA
ACCCATTCTTCATCCCCAAAATGATAGCTGATATTGCATCGGGACAGATCTCTATCATGTATGGTTTCCACGGTCCTAAC
TTCACAACAACTTCTGCTTGTGCATCTTCATCAAATGCTATTGCCGATGCATTTAACTATATCCGTTTGGGTAAAGCAAA
TGTAATTGTGGCAGGTGGTGCGGAAGCTGCTATTTTTGAAGCCGGTTTGGGCGGTTTTAACGCTATGCATGCTTTGTCTA
CCCGTAATGATGATCCGGAACGTGCATCCCGCCCGTTTAGTGCAAGCCGTGATGGCTTTGTGATGGGTGAAGGCGCAGGC
TGTCTGATTTTGGAAGAATTGGAACATGCAAAAGCACGTGGTGCCAAGATTTATGCGGAACTTGCCGGTGTAGGCGCTTC
TGCCGACGCTTATCACTTGACAGCTTCTCATCCGGAAGGATTGGGCGCTAAACTGGTGATGTTGAACGCATTGGAAGATG
CGGAATTGAAACCGGAAGATATTGATTATATCAATGTACATGGAACTTCAACTCCTGTAGGTGATGTTTCAGAAGTGAAA
GCTATCAAGGATGTATTTGGAGATCACGCTTATAAACTGAATATCAGCTCTACTAAGTCTATGACAGGACACTTGTTGGG
TGCTGCCGGTGCGGTAGAAGCTATTGCCAGCGTATTGGCTGTGAAGAATGACATTGTTCCGCCCACTATCAACCATGAGG
AAGGTGATAATGATGAAAACATTGATTATAACTTGAACTTCACGTTCAACGAAGCTCAGAAACGTACAGTAAACGCTGCA
TTGAGCAATACCTTCGGTTTTGGTGGACATAATGCATGTGTAATCGTAAAAAAATATGCTGAATAA

Upstream 100 bases:

>100_bases
TATTTCTATTCCTGATGATCAGGCTGAGAAAATTGGTACAGTAGGTGACGCCGTTTCTTATATCGAAGCTAACGCTAAGT
AATTATCCTTATTTTATAAT

Downstream 100 bases:

>100_bases
TCGTGTTTAGCAATATAAAGGATAGGATAAGACTTCTTTTTCGTAAGGATAGGGAGTCTTATCTTCGTTTTTATAAGATG
CTTGGATTCTATCCCAAAGA

Product: 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MELKRVVVTGLGALTPVGNNVAETWENLVKGVSGAGPITHFDASKFKTHFACEVKNFNGTDYIDRKELRKMDLYTQYAIA
AAKEAVEDSGMDLEKEDLNRIGVIYGVGIGGIHTFEEEVANYTLNKDTVGPKFNPFFIPKMIADIASGQISIMYGFHGPN
FTTTSACASSSNAIADAFNYIRLGKANVIVAGGAEAAIFEAGLGGFNAMHALSTRNDDPERASRPFSASRDGFVMGEGAG
CLILEELEHAKARGAKIYAELAGVGASADAYHLTASHPEGLGAKLVMLNALEDAELKPEDIDYINVHGTSTPVGDVSEVK
AIKDVFGDHAYKLNISSTKSMTGHLLGAAGAVEAIASVLAVKNDIVPPTINHEEGDNDENIDYNLNFTFNEAQKRTVNAA
LSNTFGFGGHNACVIVKKYAE

Sequences:

>Translated_421_residues
MELKRVVVTGLGALTPVGNNVAETWENLVKGVSGAGPITHFDASKFKTHFACEVKNFNGTDYIDRKELRKMDLYTQYAIA
AAKEAVEDSGMDLEKEDLNRIGVIYGVGIGGIHTFEEEVANYTLNKDTVGPKFNPFFIPKMIADIASGQISIMYGFHGPN
FTTTSACASSSNAIADAFNYIRLGKANVIVAGGAEAAIFEAGLGGFNAMHALSTRNDDPERASRPFSASRDGFVMGEGAG
CLILEELEHAKARGAKIYAELAGVGASADAYHLTASHPEGLGAKLVMLNALEDAELKPEDIDYINVHGTSTPVGDVSEVK
AIKDVFGDHAYKLNISSTKSMTGHLLGAAGAVEAIASVLAVKNDIVPPTINHEEGDNDENIDYNLNFTFNEAQKRTVNAA
LSNTFGFGGHNACVIVKKYAE
>Mature_421_residues
MELKRVVVTGLGALTPVGNNVAETWENLVKGVSGAGPITHFDASKFKTHFACEVKNFNGTDYIDRKELRKMDLYTQYAIA
AAKEAVEDSGMDLEKEDLNRIGVIYGVGIGGIHTFEEEVANYTLNKDTVGPKFNPFFIPKMIADIASGQISIMYGFHGPN
FTTTSACASSSNAIADAFNYIRLGKANVIVAGGAEAAIFEAGLGGFNAMHALSTRNDDPERASRPFSASRDGFVMGEGAG
CLILEELEHAKARGAKIYAELAGVGASADAYHLTASHPEGLGAKLVMLNALEDAELKPEDIDYINVHGTSTPVGDVSEVK
AIKDVFGDHAYKLNISSTKSMTGHLLGAAGAVEAIASVLAVKNDIVPPTINHEEGDNDENIDYNLNFTFNEAQKRTVNAA
LSNTFGFGGHNACVIVKKYAE

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=426, Percent_Identity=43.6619718309859, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI223972627, Length=152, Percent_Identity=50, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI41872631, Length=447, Percent_Identity=24.8322147651007, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1787337, Length=419, Percent_Identity=51.5513126491647, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1788663, Length=423, Percent_Identity=40.8983451536643, Blast_Score=273, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71983541, Length=418, Percent_Identity=34.4497607655502, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI71983535, Length=261, Percent_Identity=42.5287356321839, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI212642053, Length=360, Percent_Identity=25.5555555555556, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=426, Percent_Identity=26.056338028169, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320904, Length=456, Percent_Identity=34.4298245614035, Blast_Score=260, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24644341, Length=427, Percent_Identity=42.8571428571429, Blast_Score=325, Evalue=3e-89,
Organism=Drosophila melanogaster, GI19920632, Length=434, Percent_Identity=24.6543778801843, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221330659, Length=434, Percent_Identity=24.6543778801843, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24581345, Length=445, Percent_Identity=21.7977528089888, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44848; Mature: 44848

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKRVVVTGLGALTPVGNNVAETWENLVKGVSGAGPITHFDASKFKTHFACEVKNFNGT
CCCHHEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCHHHCCEEEEEEEECCCCC
DYIDRKELRKMDLYTQYAIAAAKEAVEDSGMDLEKEDLNRIGVIYGVGIGGIHTFEEEVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHH
NYTLNKDTVGPKFNPFFIPKMIADIASGQISIMYGFHGPNFTTTSACASSSNAIADAFNY
CEECCCCCCCCCCCCEEHHHHHHHHCCCCEEEEEEECCCCCCCHHHHCCCCCHHHHHHHH
IRLGKANVIVAGGAEAAIFEAGLGGFNAMHALSTRNDDPERASRPFSASRDGFVMGEGAG
HEECCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCEEEECCCC
CLILEELEHAKARGAKIYAELAGVGASADAYHLTASHPEGLGAKLVMLNALEDAELKPED
EEEHHHHHHHHHCCCEEEEHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCC
IDYINVHGTSTPVGDVSEVKAIKDVFGDHAYKLNISSTKSMTGHLLGAAGAVEAIASVLA
CCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
VKNDIVPPTINHEEGDNDENIDYNLNFTFNEAQKRTVNAALSNTFGFGGHNACVIVKKYA
HHCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
E
C
>Mature Secondary Structure
MELKRVVVTGLGALTPVGNNVAETWENLVKGVSGAGPITHFDASKFKTHFACEVKNFNGT
CCCHHEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCHHHCCEEEEEEEECCCCC
DYIDRKELRKMDLYTQYAIAAAKEAVEDSGMDLEKEDLNRIGVIYGVGIGGIHTFEEEVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHH
NYTLNKDTVGPKFNPFFIPKMIADIASGQISIMYGFHGPNFTTTSACASSSNAIADAFNY
CEECCCCCCCCCCCCEEHHHHHHHHCCCCEEEEEEECCCCCCCHHHHCCCCCHHHHHHHH
IRLGKANVIVAGGAEAAIFEAGLGGFNAMHALSTRNDDPERASRPFSASRDGFVMGEGAG
HEECCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCEEEECCCC
CLILEELEHAKARGAKIYAELAGVGASADAYHLTASHPEGLGAKLVMLNALEDAELKPED
EEEHHHHHHHHHCCCEEEEHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCC
IDYINVHGTSTPVGDVSEVKAIKDVFGDHAYKLNISSTKSMTGHLLGAAGAVEAIASVLA
CCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
VKNDIVPPTINHEEGDNDENIDYNLNFTFNEAQKRTVNAALSNTFGFGGHNACVIVKKYA
HHCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]