Click here to switch to the map view.

The map label for this gene is fabF [H]

Identifier: 150003591

GI number: 150003591

Start: 1354183

End: 1355373

Strand: Direct

Name: fabF [H]

Synonym: BVU_1020

Alternate gene names: 150003591

Gene position: 1354183-1355373 (Clockwise)

Preceding gene: 150003590

Following gene: 150003592

Centisome position: 26.23

GC content: 51.55

Gene sequence:

>1191_bases
ATGAGGAAGATCTATGTCACCGGTCTGGGAGTGATTTCGGGCATAGGGAAAGGAGTGGAAGAAAATCTGGATTCCTTGAA
AGCAGGCAAACACGGCATGGGGAAAATCACCCTTTTCCCCACCGCACTTGACGTACCCGTGTCCGAAGTAAAACAGAGCA
ATGAAGAATTAAAGAAACTCCTCTCCCTTCCATCCGGCAAAACGTATTCACGTACAGCCTTGCTAGGCTTGTTGGCTGCC
CAAGAAGCAGCCCGTGATGCGGAACTCGATTTCACTTCTCCTCGTATCGGGCTCATTTCTTCCACCTCCATCGGAGGAAT
GGATGCAAGCGAGCGGTTTTATGCCTCTTTCCGGGAAGATAACCGAAAAGGGAGATTGCGTGACATTATCTCCCATGACT
GTGGGGCCAGTACCGAAATGATAGCCGCTTATTTAGGAGTCAAAGGGACGGTGACCACCCTCAGCACCGCCTGTTCTTCC
GCCGCAAATGCTATTATGTTAGGAGCACGCCTGATTCGACACGGTTATCTGGACACCGTCCTCGTAGGCGGAACGGATGC
CTTATGCCGTTTCACGCTCAACGGTTTCAATTCACTGATGATACTGGACAAAGAGCACTGTCGTCCTTTCGACCGCACAC
GTGCCGGATTAAACCTGGGAGAAGGAGCCGGATACCTTGTTCTTCAATCTGAAAAATCCCTGATTAAAGCTCCTTATTGT
GAACTCAGCGGTTACGCCAATGCCAATGAAGCCTACCACCAGACAGGAAGTTCCCCCGACGGAGACGGGCCTTTCCTTTC
CATGAGTCAGGCCATAGCCTCTGCCGGGCTGACAGCCGGAGCCATAGACTATATCAATGTACATGGCACAGGCACTCCCA
GCAACGACGCTTCCGAAGGGAAAGCCATCCGGCGTATCTTCGGAACCCGCATCCCTCCCTTCAGTTCGGTCAAAGCATTC
ATCGGGCACACCCTGGGAGCCTCGGAAGGAATAGAAGCCGTATATTCCGTACTCTCCATCCGTCACGGACTGATTTACCC
TAGTCTGAACTTCCATCTGTCCGATGAAGAAAGCGGCCTCATCCCTGAAACGATTTTCCGGTCGGGACTTCCCATACGAC
ATGTATTATCCAACTCCTTCGGATTTGGCGGCAACAACTCATCTCTCGTATTTTCCACTCTAACCCAATAG

Upstream 100 bases:

>100_bases
TGGAAAGGAATTATGGAATCAAGATAGAGAACCCTGCCAAAGGCAAAGAAATATTCTATTCGGTACGTACCCTGGCAGAC
TACATCACCGCCCATCAGAA

Downstream 100 bases:

>100_bases
CGTATGTGCCCAGTATATATCAACCGTATCGCCTCTATCCATGCGGAAAGCAGCAATGAAAAGCCTTATTTCTCCGCACA
GGAACCTGATTATAAAGAAA

Product: 3-oxoacyl-[acyl-carrier-protein] synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MRKIYVTGLGVISGIGKGVEENLDSLKAGKHGMGKITLFPTALDVPVSEVKQSNEELKKLLSLPSGKTYSRTALLGLLAA
QEAARDAELDFTSPRIGLISSTSIGGMDASERFYASFREDNRKGRLRDIISHDCGASTEMIAAYLGVKGTVTTLSTACSS
AANAIMLGARLIRHGYLDTVLVGGTDALCRFTLNGFNSLMILDKEHCRPFDRTRAGLNLGEGAGYLVLQSEKSLIKAPYC
ELSGYANANEAYHQTGSSPDGDGPFLSMSQAIASAGLTAGAIDYINVHGTGTPSNDASEGKAIRRIFGTRIPPFSSVKAF
IGHTLGASEGIEAVYSVLSIRHGLIYPSLNFHLSDEESGLIPETIFRSGLPIRHVLSNSFGFGGNNSSLVFSTLTQ

Sequences:

>Translated_396_residues
MRKIYVTGLGVISGIGKGVEENLDSLKAGKHGMGKITLFPTALDVPVSEVKQSNEELKKLLSLPSGKTYSRTALLGLLAA
QEAARDAELDFTSPRIGLISSTSIGGMDASERFYASFREDNRKGRLRDIISHDCGASTEMIAAYLGVKGTVTTLSTACSS
AANAIMLGARLIRHGYLDTVLVGGTDALCRFTLNGFNSLMILDKEHCRPFDRTRAGLNLGEGAGYLVLQSEKSLIKAPYC
ELSGYANANEAYHQTGSSPDGDGPFLSMSQAIASAGLTAGAIDYINVHGTGTPSNDASEGKAIRRIFGTRIPPFSSVKAF
IGHTLGASEGIEAVYSVLSIRHGLIYPSLNFHLSDEESGLIPETIFRSGLPIRHVLSNSFGFGGNNSSLVFSTLTQ
>Mature_396_residues
MRKIYVTGLGVISGIGKGVEENLDSLKAGKHGMGKITLFPTALDVPVSEVKQSNEELKKLLSLPSGKTYSRTALLGLLAA
QEAARDAELDFTSPRIGLISSTSIGGMDASERFYASFREDNRKGRLRDIISHDCGASTEMIAAYLGVKGTVTTLSTACSS
AANAIMLGARLIRHGYLDTVLVGGTDALCRFTLNGFNSLMILDKEHCRPFDRTRAGLNLGEGAGYLVLQSEKSLIKAPYC
ELSGYANANEAYHQTGSSPDGDGPFLSMSQAIASAGLTAGAIDYINVHGTGTPSNDASEGKAIRRIFGTRIPPFSSVKAF
IGHTLGASEGIEAVYSVLSIRHGLIYPSLNFHLSDEESGLIPETIFRSGLPIRHVLSNSFGFGGNNSSLVFSTLTQ

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=420, Percent_Identity=30.2380952380952, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI41872631, Length=271, Percent_Identity=32.1033210332103, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223972627, Length=150, Percent_Identity=36.6666666666667, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1787337, Length=419, Percent_Identity=32.2195704057279, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1788663, Length=420, Percent_Identity=30.952380952381, Blast_Score=158, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=28.1927710843373, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=32.9545454545455, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI212642053, Length=265, Percent_Identity=26.7924528301887, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17550940, Length=257, Percent_Identity=27.2373540856031, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320904, Length=435, Percent_Identity=26.6666666666667, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24644341, Length=419, Percent_Identity=31.0262529832936, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24581345, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221330659, Length=264, Percent_Identity=26.8939393939394, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19920632, Length=257, Percent_Identity=27.2373540856031, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42022; Mature: 42022

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIYVTGLGVISGIGKGVEENLDSLKAGKHGMGKITLFPTALDVPVSEVKQSNEELKKL
CCEEEEECHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
LSLPSGKTYSRTALLGLLAAQEAARDAELDFTSPRIGLISSTSIGGMDASERFYASFRED
HCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHC
NRKGRLRDIISHDCGASTEMIAAYLGVKGTVTTLSTACSSAANAIMLGARLIRHGYLDTV
CCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LVGGTDALCRFTLNGFNSLMILDKEHCRPFDRTRAGLNLGEGAGYLVLQSEKSLIKAPYC
EECCCHHHHHEECCCCCEEEEEEHHHCCCHHHHHCCCCCCCCCCEEEECCCCHHHHCCCH
ELSGYANANEAYHQTGSSPDGDGPFLSMSQAIASAGLTAGAIDYINVHGTGTPSNDASEG
HHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHH
KAIRRIFGTRIPPFSSVKAFIGHTLGASEGIEAVYSVLSIRHGLIYPSLNFHLSDEESGL
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEECCCCEEEECCCCCCC
IPETIFRSGLPIRHVLSNSFGFGGNNSSLVFSTLTQ
CHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MRKIYVTGLGVISGIGKGVEENLDSLKAGKHGMGKITLFPTALDVPVSEVKQSNEELKKL
CCEEEEECHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
LSLPSGKTYSRTALLGLLAAQEAARDAELDFTSPRIGLISSTSIGGMDASERFYASFRED
HCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHC
NRKGRLRDIISHDCGASTEMIAAYLGVKGTVTTLSTACSSAANAIMLGARLIRHGYLDTV
CCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LVGGTDALCRFTLNGFNSLMILDKEHCRPFDRTRAGLNLGEGAGYLVLQSEKSLIKAPYC
EECCCHHHHHEECCCCCEEEEEEHHHCCCHHHHHCCCCCCCCCCEEEECCCCHHHHCCCH
ELSGYANANEAYHQTGSSPDGDGPFLSMSQAIASAGLTAGAIDYINVHGTGTPSNDASEG
HHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHH
KAIRRIFGTRIPPFSSVKAFIGHTLGASEGIEAVYSVLSIRHGLIYPSLNFHLSDEESGL
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEECCCCEEEECCCCCCC
IPETIFRSGLPIRHVLSNSFGFGGNNSSLVFSTLTQ
CHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]