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The map label for this gene is luxS

Identifier: 150003468

GI number: 150003468

Start: 1202647

End: 1203132

Strand: Direct

Name: luxS

Synonym: BVU_0895

Alternate gene names: 150003468

Gene position: 1202647-1203132 (Clockwise)

Preceding gene: 150003467

Following gene: 150003476

Centisome position: 23.29

GC content: 46.71

Gene sequence:

>486_bases
ATGAAGACAATACCCAGTTTTACCATTGACCATATCCGCTTGCTTCGCGGTATCTATGTATCCAGAAAAGACGAAGTGGG
CGGTGAAACGGTCACCACCTTTGACATCCGCATGAAAGAACCCAACCGGGAACCTGCTTTGGGACAAGGAGCCTTGCATA
CCATAGAGCATCTAGCCGCTACCTACCTGCGTAACCACCCTATATGGTCTGACAAAATTGTCTACTGGGGACCGATGGGA
TGCCTCACCGGTAACTACCTGTTAATGAAAGGCGATTTAAAATCGGAAGATATTGTAGAACTGATGCAGGAAACGTTCCG
CTTTGTAGCCGATTTTGAAGGCGAAGTTCCGGGAGCCGCCCCTAAAGATTGCGGTAACTACTTGCTTCACGACCTACCTA
TGGCCAAATGGGAGTCGGCCAAATATCTGCATGAAGTATTGGAGCACATGACAAAAGATAATCTGTATTATCCTACTAAA
GAGTAA

Upstream 100 bases:

>100_bases
AACAATACACAAATTTTTGGGAGACTATAGCCGACCGTTCCTTCGAGGTCACTCATACCTTCCTTTCCTCATTACCAGCT
AATTTATAAAAACGAATAAT

Downstream 100 bases:

>100_bases
TTCTCAACAACAGAACAGTAGAAACGTAATAACAGAAAATAGAAAAGCCGCTTTCTTTTCAGAGAGCGGCTTTTCTTTAA
GTCCTTTTCAATAGAGATTG

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MKTIPSFTIDHIRLLRGIYVSRKDEVGGETVTTFDIRMKEPNREPALGQGALHTIEHLAATYLRNHPIWSDKIVYWGPMG
CLTGNYLLMKGDLKSEDIVELMQETFRFVADFEGEVPGAAPKDCGNYLLHDLPMAKWESAKYLHEVLEHMTKDNLYYPTK
E

Sequences:

>Translated_161_residues
MKTIPSFTIDHIRLLRGIYVSRKDEVGGETVTTFDIRMKEPNREPALGQGALHTIEHLAATYLRNHPIWSDKIVYWGPMG
CLTGNYLLMKGDLKSEDIVELMQETFRFVADFEGEVPGAAPKDCGNYLLHDLPMAKWESAKYLHEVLEHMTKDNLYYPTK
E
>Mature_161_residues
MKTIPSFTIDHIRLLRGIYVSRKDEVGGETVTTFDIRMKEPNREPALGQGALHTIEHLAATYLRNHPIWSDKIVYWGPMG
CLTGNYLLMKGDLKSEDIVELMQETFRFVADFEGEVPGAAPKDCGNYLLHDLPMAKWESAKYLHEVLEHMTKDNLYYPTK
E

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=166, Percent_Identity=27.1084337349398, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_BACV8 (A6KYS6)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298212.1
- ProteinModelPortal:   A6KYS6
- SMR:   A6KYS6
- STRING:   A6KYS6
- GeneID:   5301862
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_0895
- NMPDR:   fig|435590.6.peg.853
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   TTFDIRM
- ProtClustDB:   PRK02260
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18472; Mature: 18472

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIPSFTIDHIRLLRGIYVSRKDEVGGETVTTFDIRMKEPNREPALGQGALHTIEHLAA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHH
TYLRNHPIWSDKIVYWGPMGCLTGNYLLMKGDLKSEDIVELMQETFRFVADFEGEVPGAA
HHHHCCCCCCCCEEEECCHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
PKDCGNYLLHDLPMAKWESAKYLHEVLEHMTKDNLYYPTKE
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKTIPSFTIDHIRLLRGIYVSRKDEVGGETVTTFDIRMKEPNREPALGQGALHTIEHLAA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHH
TYLRNHPIWSDKIVYWGPMGCLTGNYLLMKGDLKSEDIVELMQETFRFVADFEGEVPGAA
HHHHCCCCCCCCEEEECCHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
PKDCGNYLLHDLPMAKWESAKYLHEVLEHMTKDNLYYPTKE
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA