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The map label for this gene is yiaY [H]

Identifier: 150003342

GI number: 150003342

Start: 1065609

End: 1066781

Strand: Direct

Name: yiaY [H]

Synonym: BVU_0760

Alternate gene names: 150003342

Gene position: 1065609-1066781 (Clockwise)

Preceding gene: 150003338

Following gene: 150003343

Centisome position: 20.64

GC content: 45.1

Gene sequence:

>1173_bases
ATGAAAGCAAATCCTGTATTTAGTTTATACATCCCTACCAAATTAGTATTTGGCTGCGAAGAAATCAAGAAATTATCCAG
TGAAAAATTACCGGGAAAAAAGGCACTGGTCGTCATCTCATCCGGAACTTCCATGCGAAAATATGGATATTTGGAGAGAG
TACTTGCCCAATTAAGACTGAATAATGTAGAAACACTGGTTTACGATAAAATCCTTCCCAACCCCATCAAAGAACACGTC
ATGGAAGCAGCCGCCATCTGCCGGGAGGAAAAGTGCGACTTTGTAGTAGGACTGGGAGGCGGAAGTTCCATCGACTCCGC
CAAAAGTATAGCTGTTATGGCCTGCAACGATGGTGACTACTGGGATTATGTATCAGGGGGTAGTGGTAAAGGACGCCCTG
TTACCAAAGCACTTCCCATTATCGCCATACCTACTACCGCCGGAACCGGAACAGAAATGGATCCATGGACAGTGATTACC
CACGAAACGGCTCAAGAAAAGATAGGCTTCGGTTGTCAGCTGACTTTCCCTACCTTATCTATTGTAGACCCGGAACTGAT
GGTTTCCATTCCTCCGCACCTCACCGCCTATCAAGGGTTCGATGCATTCTTCCATGCCGCAGAGGGTTTTATCGCCAATT
GTGCAACACCCATCAGTGATCTTTACGCCTTAGAAGCCATCCGTCTGATCTACAAATATCTGCCAGTAGCCGTAGCCGAC
GGAAAGAATTTGAAAGCGCGTGCCAAAATTGCTTGGGCCAGCACCTTGGCAGGCATGGTGGAAGCCACTTCAAGCTGCAC
TTCCGAACATTCATTAGAACATGCCATGAGTGCTTATTATCCACAACTTCCTCATGGAGCAGGACTCATTGCCTTGTCTG
AGGCATACTTCGAAACTTTCCGGCATGACTGTACAAAACGTTACATGAAAATGGCTGAAATGATGACCCAGAAAAAGAGC
AACCGTCCGTCCGATTTCATTGATGCATTGATTACACTGCAAAAAGAATGTAAAGTACATTCTATCAAACTGAGCGAATT
TGGTATCCAATCCGAAGATTTCCCCAAATTCCTGCAAAATGCAAGAGATACGATGGGAGGACTGTTCACTCTCGACCCAC
GCCCGATTACAGACGAAGAAATCCTGCATATCTTTAAAAATTCTTATAAATAA

Upstream 100 bases:

>100_bases
AATACAATCCGGCAGTATGTAAAATTTAACAAATTACTTAAACAAGCAAACTATTATTTTCCTACATTTGTTACCAGTGA
AACTTTAAATACGAAAGAAC

Downstream 100 bases:

>100_bases
TGGATAAAGAACTAGACCTTGCCGTAACCTGTTACGGCAAGGTAAAACCATTGAAATATGATTTGGTCCTCCTCCCTTGG
GGAGCTACCGAACCGCATAA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKANPVFSLYIPTKLVFGCEEIKKLSSEKLPGKKALVVISSGTSMRKYGYLERVLAQLRLNNVETLVYDKILPNPIKEHV
MEAAAICREEKCDFVVGLGGGSSIDSAKSIAVMACNDGDYWDYVSGGSGKGRPVTKALPIIAIPTTAGTGTEMDPWTVIT
HETAQEKIGFGCQLTFPTLSIVDPELMVSIPPHLTAYQGFDAFFHAAEGFIANCATPISDLYALEAIRLIYKYLPVAVAD
GKNLKARAKIAWASTLAGMVEATSSCTSEHSLEHAMSAYYPQLPHGAGLIALSEAYFETFRHDCTKRYMKMAEMMTQKKS
NRPSDFIDALITLQKECKVHSIKLSEFGIQSEDFPKFLQNARDTMGGLFTLDPRPITDEEILHIFKNSYK

Sequences:

>Translated_390_residues
MKANPVFSLYIPTKLVFGCEEIKKLSSEKLPGKKALVVISSGTSMRKYGYLERVLAQLRLNNVETLVYDKILPNPIKEHV
MEAAAICREEKCDFVVGLGGGSSIDSAKSIAVMACNDGDYWDYVSGGSGKGRPVTKALPIIAIPTTAGTGTEMDPWTVIT
HETAQEKIGFGCQLTFPTLSIVDPELMVSIPPHLTAYQGFDAFFHAAEGFIANCATPISDLYALEAIRLIYKYLPVAVAD
GKNLKARAKIAWASTLAGMVEATSSCTSEHSLEHAMSAYYPQLPHGAGLIALSEAYFETFRHDCTKRYMKMAEMMTQKKS
NRPSDFIDALITLQKECKVHSIKLSEFGIQSEDFPKFLQNARDTMGGLFTLDPRPITDEEILHIFKNSYK
>Mature_390_residues
MKANPVFSLYIPTKLVFGCEEIKKLSSEKLPGKKALVVISSGTSMRKYGYLERVLAQLRLNNVETLVYDKILPNPIKEHV
MEAAAICREEKCDFVVGLGGGSSIDSAKSIAVMACNDGDYWDYVSGGSGKGRPVTKALPIIAIPTTAGTGTEMDPWTVIT
HETAQEKIGFGCQLTFPTLSIVDPELMVSIPPHLTAYQGFDAFFHAAEGFIANCATPISDLYALEAIRLIYKYLPVAVAD
GKNLKARAKIAWASTLAGMVEATSSCTSEHSLEHAMSAYYPQLPHGAGLIALSEAYFETFRHDCTKRYMKMAEMMTQKKS
NRPSDFIDALITLQKECKVHSIKLSEFGIQSEDFPKFLQNARDTMGGLFTLDPRPITDEEILHIFKNSYK

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=392, Percent_Identity=27.0408163265306, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI48994951, Length=386, Percent_Identity=33.419689119171, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI87082107, Length=317, Percent_Identity=32.4921135646688, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789386, Length=362, Percent_Identity=27.6243093922652, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789163, Length=387, Percent_Identity=28.6821705426357, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787493, Length=350, Percent_Identity=27.7142857142857, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17537053, Length=301, Percent_Identity=29.5681063122924, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321181, Length=394, Percent_Identity=32.48730964467, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24657991, Length=372, Percent_Identity=26.3440860215054, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 42963; Mature: 42963

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKANPVFSLYIPTKLVFGCEEIKKLSSEKLPGKKALVVISSGTSMRKYGYLERVLAQLRL
CCCCCEEEEEECHHHHHCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
NNVETLVYDKILPNPIKEHVMEAAAICREEKCDFVVGLGGGSSIDSAKSIAVMACNDGDY
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECCCCC
WDYVSGGSGKGRPVTKALPIIAIPTTAGTGTEMDPWTVITHETAQEKIGFGCQLTFPTLS
CCCCCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCEEEEECCHHHHHHCCCEEEECCCCE
IVDPELMVSIPPHLTAYQGFDAFFHAAEGFIANCATPISDLYALEAIRLIYKYLPVAVAD
EECCHHEEECCCCCCHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCEEEEC
GKNLKARAKIAWASTLAGMVEATSSCTSEHSLEHAMSAYYPQLPHGAGLIALSEAYFETF
CCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHH
RHDCTKRYMKMAEMMTQKKSNRPSDFIDALITLQKECKVHSIKLSEFGIQSEDFPKFLQN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEHHHCCCCCCHHHHHHHH
ARDTMGGLFTLDPRPITDEEILHIFKNSYK
HHHHHCCEEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKANPVFSLYIPTKLVFGCEEIKKLSSEKLPGKKALVVISSGTSMRKYGYLERVLAQLRL
CCCCCEEEEEECHHHHHCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
NNVETLVYDKILPNPIKEHVMEAAAICREEKCDFVVGLGGGSSIDSAKSIAVMACNDGDY
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECCCCC
WDYVSGGSGKGRPVTKALPIIAIPTTAGTGTEMDPWTVITHETAQEKIGFGCQLTFPTLS
CCCCCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCEEEEECCHHHHHHCCCEEEECCCCE
IVDPELMVSIPPHLTAYQGFDAFFHAAEGFIANCATPISDLYALEAIRLIYKYLPVAVAD
EECCHHEEECCCCCCHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCEEEEC
GKNLKARAKIAWASTLAGMVEATSSCTSEHSLEHAMSAYYPQLPHGAGLIALSEAYFETF
CCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHH
RHDCTKRYMKMAEMMTQKKSNRPSDFIDALITLQKECKVHSIKLSEFGIQSEDFPKFLQN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEHHHCCCCCCHHHHHHHH
ARDTMGGLFTLDPRPITDEEILHIFKNSYK
HHHHHCCEEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]