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The map label for this gene is ipk [H]

Identifier: 148828407

GI number: 148828407

Start: 1861276

End: 1862229

Strand: Reverse

Name: ipk [H]

Synonym: CGSHiGG_10080

Alternate gene names: 148828407

Gene position: 1862229-1861276 (Counterclockwise)

Preceding gene: 148828408

Following gene: 148828406

Centisome position: 98.68

GC content: 37.21

Gene sequence:

>954_bases
ATGAATACATTAATGAAATCACGTCAATTTTCTACCGCACTTTGCCAAAATACAACACAATCAAATGGGCAGCCATTACG
CTTCCCTAGCCCAGCCAAACTGAATTTATTTCTTTATATCAATGGAAAATTGCCGAACGGCTATCATGAATTACAAACGC
TTTTCCAATTTTTAGATTTTGGCGATTGGTTAGACATTAGTATTCGGGAACAAGATAATCAAATTGTTTTAACGCCAGAA
ATTCCAAATCTAAAAACGGAAAATAATCTAATTTATCGAGCCGCAAAACTTTTACAAGAAAAAGCCAATATTCAATTGGG
TGCAAATATTCATTTAGATAAAATTCTTCCAATGGGAGGCGGTGTTGGTGGTGGTTCATCCAATGCAGCAACCGCATTAG
TCGCTTTAAATTATTTATGGCAAGCCAATTTATCCATTGATGAACTAGCAAAATTGGGATTAACATTAGGCGCGGATGTG
CCAATATTTGTACATGGACACGCAGCTTTTGCTGAAGGCGTTGGGGAAAAAATCACTTATTGTGAACCTGCCGAAAAATG
GTTTGTTATATTAAAACCCGATGATTCAATATCGACGGCTGTCATCTTTCAAGATCCAAATTTACCACGTAATACACCGA
AAAAATCCCTCGAACAACTTTTGAGTGAACCTTATAAAAACGATTGCGAAAAAGTTGTGATAAATCATTATTCAAACGTT
GAAAAAGCGTTAAACTGGTTGCTACAATATGCGCCGGCAAGATTAACAGGAACGGGAGCCTGTGTTTTTGCTGAATTTGA
TCATGAAGCAGAAGCGCAAGCGGTATTTAGACAAAAACCAGAAGCATTTTTTGGTTTCATCGCTAAAGGACTCAATGTGT
CTCCCTTGCACGCAATGTTGAAGCAGCTATCATCAACTCATACTCATAGACAATCTAAACCTGAGGTTTTATAA

Upstream 100 bases:

>100_bases
TAACCTATCACTCAAATAATTCGATGCCTGAAAATATTTTGCTGAAAAATGACAGCACAAAACAAACCTTAAAAATTCGC
GTAGACGAGTGGATTTACTA

Downstream 100 bases:

>100_bases
AATGCCTGACATTAAACTCTTCGCAGGTAATGCTACACCTGAACTTGCAAAACGTATTTCTGAACGTTTATATATTTCAC
TAGGCGATGCAACAGTCGCT

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNTLMKSRQFSTALCQNTTQSNGQPLRFPSPAKLNLFLYINGKLPNGYHELQTLFQFLDFGDWLDISIREQDNQIVLTPE
IPNLKTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGGGVGGGSSNAATALVALNYLWQANLSIDELAKLGLTLGADV
PIFVHGHAAFAEGVGEKITYCEPAEKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLEQLLSEPYKNDCEKVVINHYSNV
EKALNWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFIAKGLNVSPLHAMLKQLSSTHTHRQSKPEVL

Sequences:

>Translated_317_residues
MNTLMKSRQFSTALCQNTTQSNGQPLRFPSPAKLNLFLYINGKLPNGYHELQTLFQFLDFGDWLDISIREQDNQIVLTPE
IPNLKTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGGGVGGGSSNAATALVALNYLWQANLSIDELAKLGLTLGADV
PIFVHGHAAFAEGVGEKITYCEPAEKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLEQLLSEPYKNDCEKVVINHYSNV
EKALNWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFIAKGLNVSPLHAMLKQLSSTHTHRQSKPEVL
>Mature_317_residues
MNTLMKSRQFSTALCQNTTQSNGQPLRFPSPAKLNLFLYINGKLPNGYHELQTLFQFLDFGDWLDISIREQDNQIVLTPE
IPNLKTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGGGVGGGSSNAATALVALNYLWQANLSIDELAKLGLTLGADV
PIFVHGHAAFAEGVGEKITYCEPAEKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLEQLLSEPYKNDCEKVVINHYSNV
EKALNWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFIAKGLNVSPLHAMLKQLSSTHTHRQSKPEVL

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=281, Percent_Identity=60.4982206405694, Blast_Score=327, Evalue=7e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 35158; Mature: 35158

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLMKSRQFSTALCQNTTQSNGQPLRFPSPAKLNLFLYINGKLPNGYHELQTLFQFLDF
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCC
GDWLDISIREQDNQIVLTPEIPNLKTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGG
CCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEECCCEEEHHEEECCC
GVGGGSSNAATALVALNYLWQANLSIDELAKLGLTLGADVPIFVHGHAAFAEGVGEKITY
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCCEE
CEPAEKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLEQLLSEPYKNDCEKVVINHYSNV
ECCCCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCH
EKALNWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFIAKGLNVSPLHAML
HHHHHHHHHHCCCEEECCCEEEEEECCCCHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHH
KQLSSTHTHRQSKPEVL
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNTLMKSRQFSTALCQNTTQSNGQPLRFPSPAKLNLFLYINGKLPNGYHELQTLFQFLDF
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCC
GDWLDISIREQDNQIVLTPEIPNLKTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGG
CCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEECCCEEEHHEEECCC
GVGGGSSNAATALVALNYLWQANLSIDELAKLGLTLGADVPIFVHGHAAFAEGVGEKITY
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCCEE
CEPAEKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLEQLLSEPYKNDCEKVVINHYSNV
ECCCCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCH
EKALNWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFIAKGLNVSPLHAML
HHHHHHHHHHCCCEEECCCEEEEEECCCCHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHH
KQLSSTHTHRQSKPEVL
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA