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The map label for this gene is hemH [H]

Identifier: 148828320

GI number: 148828320

Start: 1764859

End: 1765182

Strand: Direct

Name: hemH [H]

Synonym: CGSHiGG_09520

Alternate gene names: 148828320

Gene position: 1764859-1765182 (Clockwise)

Preceding gene: 148828313

Following gene: 148828322

Centisome position: 93.52

GC content: 37.04

Gene sequence:

>324_bases
ATGGAAACCTTAGACAAAATCAAAAAGCAAATTAGTGAAAATCCCATTCTTATTTATATGAAAGGTTCGCCAAAATTACC
ATCTTGTGGTTTTTCTGCTCGTGCATCTGAGGCATTAATGCACTGCAAAGTGCCTTTTGGTTATGTGGATATTTTGCAAC
ATCCAGATATTCGCGCTGAATTACCAACATATGCAAATTGGCCAACTTTCCCACAATTATGGGTTGAGGGAGAATTAATT
GGTGGTTGTGATATTATTTTAGAAATGTATCAAGCAGGCGAATTGCAAACTTTATTAGCTGAAGTGGCAGCAAAGCACGC
TTAA

Upstream 100 bases:

>100_bases
CGGTTTAGGCCTTTTGTTTTAAATGAATATAAAACCAAGCATTTCAATCAAGTTTTAACTTGTGATAAAATGCTTGCCTC
GTTTATTTATAGGGAACATT

Downstream 100 bases:

>100_bases
TCACAGTGGAAAAATAAAACCCGCAATAAGCGGGTTTTTTATATAATAAATTTCCCTTTCATTATTAAATAATAGATTAA
GCAAACTTTAATACCTTAGA

Product: ferrochelatase

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
METLDKIKKQISENPILIYMKGSPKLPSCGFSARASEALMHCKVPFGYVDILQHPDIRAELPTYANWPTFPQLWVEGELI
GGCDIILEMYQAGELQTLLAEVAAKHA

Sequences:

>Translated_107_residues
METLDKIKKQISENPILIYMKGSPKLPSCGFSARASEALMHCKVPFGYVDILQHPDIRAELPTYANWPTFPQLWVEGELI
GGCDIILEMYQAGELQTLLAEVAAKHA
>Mature_107_residues
METLDKIKKQISENPILIYMKGSPKLPSCGFSARASEALMHCKVPFGYVDILQHPDIRAELPTYANWPTFPQLWVEGELI
GGCDIILEMYQAGELQTLLAEVAAKHA

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI95113651, Length=93, Percent_Identity=43.010752688172, Blast_Score=89, Evalue=6e-19,
Organism=Homo sapiens, GI42516576, Length=95, Percent_Identity=36.8421052631579, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787943, Length=104, Percent_Identity=74.0384615384615, Blast_Score=173, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71988159, Length=80, Percent_Identity=42.5, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71988153, Length=80, Percent_Identity=42.5, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17556042, Length=101, Percent_Identity=33.6633663366337, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325198, Length=107, Percent_Identity=39.2523364485981, Blast_Score=89, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321022, Length=83, Percent_Identity=42.1686746987952, Blast_Score=87, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320303, Length=83, Percent_Identity=43.3734939759036, Blast_Score=87, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24642023, Length=93, Percent_Identity=38.7096774193548, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI19921242, Length=95, Percent_Identity=41.0526315789474, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 11931; Mature: 11931

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLDKIKKQISENPILIYMKGSPKLPSCGFSARASEALMHCKVPFGYVDILQHPDIRAE
CCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCC
LPTYANWPTFPQLWVEGELIGGCDIILEMYQAGELQTLLAEVAAKHA
CCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
METLDKIKKQISENPILIYMKGSPKLPSCGFSARASEALMHCKVPFGYVDILQHPDIRAE
CCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCC
LPTYANWPTFPQLWVEGELIGGCDIILEMYQAGELQTLLAEVAAKHA
CCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]