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The map label for this gene is ddl [H]

Identifier: 148828302

GI number: 148828302

Start: 1739412

End: 1740689

Strand: Direct

Name: ddl [H]

Synonym: CGSHiGG_09370

Alternate gene names: 148828302

Gene position: 1739412-1740689 (Clockwise)

Preceding gene: 148828301

Following gene: 148828303

Centisome position: 92.17

GC content: 39.05

Gene sequence:

>1278_bases
ATGGTTAAAGGTGTGGAAACAAAAACAATAGTAGGTTTAGAGGTTGGCACGTCAAAAGTGGTCGCTGTAGTTGGCGAAGT
ATTTCCTGATGGTGTAGTGAATGTGCTTGGTGTAGGCAGTTGTCCTTCAAAAGGGATTGATCGTGGCAGCATCACTGATC
TTGATGCCGTGGTGGGTTCGATTCAACGTGCTATTGAAGCGGCAGAATCTATGGCTGATTGTCAGATTATGAGTGTGACT
TTAGCCATTACTGGAGAGCATATTCAAAGCCTCAATGAAAGTGGTTTTGTGCCGATAGCAGAAAGTGAAGTAACACAAGA
GGAAATCGATTCCGCACTTCATACAGCAAGCTCAATAAAATTGCCAGAAGGCTTATCTTTATTGCATGTTATTCCACAAG
AATACGCTGTTGATCGTCAGATGAACATTAAAAATCCATTAGGATTACAAGGCGTGCGTTTAAAAGCACAAGTACATTTG
ATCGCTTGTCATCAAGATTGGCAAAATAACTTAAAAAAAGCCATTGAACGTTGTGGATTGCAAGTGGATAAAGTGGTTTT
CTCTGGTTTTGCAGCAACACATTCTGTGCTAACTGAGGATGAAAAAGATCTCGGCGTGTGTTTAATTGATTTTGGTGCTG
GCACAATGAACGTGATGGTTTATACGAATGGCGCATTACGTTTTAGCAAGGTAATTCCTTACGCAGGAAATATTGTGACA
AATGATATTGCGCATGCTTGTACAATTTCGCGGGCAGAAGCAGAACGGATCAAAGTGAACTATGCTAGTGCATTTTACCC
AGCTCGTTTGCACGGAGATAAAAAAATTGAAGTGGCAAGTATTGGCGGTCGTGCGCCTCGTTCATTAACAAAAAGTGATT
TATCTTTAATTACATCAGCTCGTTATACAGAGCTTTTAGGCGTGGTAAAAGATGAATTAGATAAGTTAAAAGCTGAATTA
GAAGCAAAACATATTAAATTTGAATTAATTGCAGGCGTGGTAATAACTGGTGGTGGAGCGCAGATTGAAGATCTTAAAGA
ATGCGCTTCAAATGTTTTCCATTGTCAGGTGCGTATTGCGAGTCCATTAAATATTACTGGTTTGACTGATTACGTGAATC
GTCCACAATATTCAACGGTGGTGGGACTATTGCAATATAATTACAGTAATAGTGATGATGATTTAATTTCAGGAAGTGAT
GATTCTGAAGGAACTTTCTTTGAATCTATTTGGCAAGGAGTAAAAAAAATTGTCAATAAAGTGCGGTCAGAATTTTGA

Upstream 100 bases:

>100_bases
TTGATGTGCCAGAAAACAAAAAATAGATTATATAGATTTAAGATATACGGCAGGTGCTGCTGTAGGTATGATTGATAGAT
AAAAATAACTGGGTGCGAAA

Downstream 100 bases:

>100_bases
TTATTTTTAATTTTTCATCTACAATAAAGGGAATTTATATTTTATATATTTAGTCAGCTTATCTGGCAGTAACGGAGAAC
ATCAATGCTATACCCAGAGT

Product: D-alanine--D-alanine ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MVKGVETKTIVGLEVGTSKVVAVVGEVFPDGVVNVLGVGSCPSKGIDRGSITDLDAVVGSIQRAIEAAESMADCQIMSVT
LAITGEHIQSLNESGFVPIAESEVTQEEIDSALHTASSIKLPEGLSLLHVIPQEYAVDRQMNIKNPLGLQGVRLKAQVHL
IACHQDWQNNLKKAIERCGLQVDKVVFSGFAATHSVLTEDEKDLGVCLIDFGAGTMNVMVYTNGALRFSKVIPYAGNIVT
NDIAHACTISRAEAERIKVNYASAFYPARLHGDKKIEVASIGGRAPRSLTKSDLSLITSARYTELLGVVKDELDKLKAEL
EAKHIKFELIAGVVITGGGAQIEDLKECASNVFHCQVRIASPLNITGLTDYVNRPQYSTVVGLLQYNYSNSDDDLISGSD
DSEGTFFESIWQGVKKIVNKVRSEF

Sequences:

>Translated_425_residues
MVKGVETKTIVGLEVGTSKVVAVVGEVFPDGVVNVLGVGSCPSKGIDRGSITDLDAVVGSIQRAIEAAESMADCQIMSVT
LAITGEHIQSLNESGFVPIAESEVTQEEIDSALHTASSIKLPEGLSLLHVIPQEYAVDRQMNIKNPLGLQGVRLKAQVHL
IACHQDWQNNLKKAIERCGLQVDKVVFSGFAATHSVLTEDEKDLGVCLIDFGAGTMNVMVYTNGALRFSKVIPYAGNIVT
NDIAHACTISRAEAERIKVNYASAFYPARLHGDKKIEVASIGGRAPRSLTKSDLSLITSARYTELLGVVKDELDKLKAEL
EAKHIKFELIAGVVITGGGAQIEDLKECASNVFHCQVRIASPLNITGLTDYVNRPQYSTVVGLLQYNYSNSDDDLISGSD
DSEGTFFESIWQGVKKIVNKVRSEF
>Mature_425_residues
MVKGVETKTIVGLEVGTSKVVAVVGEVFPDGVVNVLGVGSCPSKGIDRGSITDLDAVVGSIQRAIEAAESMADCQIMSVT
LAITGEHIQSLNESGFVPIAESEVTQEEIDSALHTASSIKLPEGLSLLHVIPQEYAVDRQMNIKNPLGLQGVRLKAQVHL
IACHQDWQNNLKKAIERCGLQVDKVVFSGFAATHSVLTEDEKDLGVCLIDFGAGTMNVMVYTNGALRFSKVIPYAGNIVT
NDIAHACTISRAEAERIKVNYASAFYPARLHGDKKIEVASIGGRAPRSLTKSDLSLITSARYTELLGVVKDELDKLKAEL
EAKHIKFELIAGVVITGGGAQIEDLKECASNVFHCQVRIASPLNITGLTDYVNRPQYSTVVGLLQYNYSNSDDDLISGSD
DSEGTFFESIWQGVKKIVNKVRSEF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=425, Percent_Identity=52.7058823529412, Blast_Score=470, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45823; Mature: 45823

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKGVETKTIVGLEVGTSKVVAVVGEVFPDGVVNVLGVGSCPSKGIDRGSITDLDAVVGS
CCCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCCCCHHHHHHHH
IQRAIEAAESMADCQIMSVTLAITGEHIQSLNESGFVPIAESEVTQEEIDSALHTASSIK
HHHHHHHHHHHCCCEEEEEEEEEECHHHHHCCCCCCEEECCHHCCHHHHHHHHHHHHCCC
LPEGLSLLHVIPQEYAVDRQMNIKNPLGLQGVRLKAQVHLIACHQDWQNNLKKAIERCGL
CCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEECHHHHHHHHHHHHHHCC
QVDKVVFSGFAATHSVLTEDEKDLGVCLIDFGAGTMNVMVYTNGALRFSKVIPYAGNIVT
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEHHCCCCCCCHH
NDIAHACTISRAEAERIKVNYASAFYPARLHGDKKIEVASIGGRAPRSLTKSDLSLITSA
HHHHHHHHHCCCCHHHEEEEEHHHCCCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHHH
RYTELLGVVKDELDKLKAELEAKHIKFELIAGVVITGGGAQIEDLKECASNVFHCQVRIA
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCHHHHHHHHCCEEEEEEEEC
SPLNITGLTDYVNRPQYSTVVGLLQYNYSNSDDDLISGSDDSEGTFFESIWQGVKKIVNK
CCCCCCCCHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VRSEF
HHHCC
>Mature Secondary Structure
MVKGVETKTIVGLEVGTSKVVAVVGEVFPDGVVNVLGVGSCPSKGIDRGSITDLDAVVGS
CCCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCCCCHHHHHHHH
IQRAIEAAESMADCQIMSVTLAITGEHIQSLNESGFVPIAESEVTQEEIDSALHTASSIK
HHHHHHHHHHHCCCEEEEEEEEEECHHHHHCCCCCCEEECCHHCCHHHHHHHHHHHHCCC
LPEGLSLLHVIPQEYAVDRQMNIKNPLGLQGVRLKAQVHLIACHQDWQNNLKKAIERCGL
CCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEECHHHHHHHHHHHHHHCC
QVDKVVFSGFAATHSVLTEDEKDLGVCLIDFGAGTMNVMVYTNGALRFSKVIPYAGNIVT
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEHHCCCCCCCHH
NDIAHACTISRAEAERIKVNYASAFYPARLHGDKKIEVASIGGRAPRSLTKSDLSLITSA
HHHHHHHHHCCCCHHHEEEEEHHHCCCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHHH
RYTELLGVVKDELDKLKAELEAKHIKFELIAGVVITGGGAQIEDLKECASNVFHCQVRIA
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCHHHHHHHHCCEEEEEEEEC
SPLNITGLTDYVNRPQYSTVVGLLQYNYSNSDDDLISGSDDSEGTFFESIWQGVKKIVNK
CCCCCCCCHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VRSEF
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]