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The map label for this gene is mraW [H]

Identifier: 148828289

GI number: 148828289

Start: 1725301

End: 1726170

Strand: Direct

Name: mraW [H]

Synonym: CGSHiGG_09305

Alternate gene names: 148828289

Gene position: 1725301-1726170 (Clockwise)

Preceding gene: 148828288

Following gene: 148828290

Centisome position: 91.42

GC content: 37.24

Gene sequence:

>870_bases
ATGAATAGCGAAAATTCCTTTTCTTCATCTGAACATATTACAGTTTTACTTCACGAAGCCGTGAATGGCTTGGCATTGAA
GGAGAATGGCATTTATATTGATGGTACTTTTGGGCGTGGGGGGCATTCTCGGTTTATCCTTTCTCAACTTTCTTCTAATG
GTCGTTTGATAGCTGTAGATCGCGATCCTCGTGCTATTGCAGAAGCACACAAAATCCAAGACTTGCGTTTTCAGATTGAA
CATAACAGCTTTTCGCATATTCCTGAAATTTGTGACAAATTAAATTTAGTGGGCAAAATTGACGGTATTTTGCTTGATCT
TGGTGTGTCTTCTCCTCAGCTTGATGAAGCAGAACGTGGTTTTAGTTTTATGAAAGATGGTCCGCTTGATATGCGTATGG
ATACAACTCAAGGTTTATCTGCTGAAGAATGGTTAAAACAAGTGTCCATTGAGGATTTAACTTGGGTGTTGAAAACTTTT
GGCGAAGAGCGTTTCGCTAAACGTATTGCCACTGCTATTGTTGATTTCAATAAAAGTGCGGTAAAAAATGGCACAGAATT
TTTATCGCGTACCAGTCAATTGGCGGAACTTATTTCACAGGCAGTTCCTTTTAAAGATAAACATAAACATCCTGCGACGC
GTAGTTTCCAAGCTATTCGTATTTTTATTAATTCGGAATTAGATGAATTAGAAAGTCTGCTTAATTCTGCGTTAGATATG
TTAGCACCAGAAGGTCGTTTATCAATTATTAGTTTCCATTCTTTAGAAGATAGAATGGTGAAACATTTTATGAAAAACAA
AGTAAGGGCGAGGATATTCCCAAAGGTTTACCATTGCGAGAAGATCAAATTCAGCGTAATCAAAAATTAA

Upstream 100 bases:

>100_bases
TGCAGAGGATATAGAAATTGGCTCCAGCGCAGATTTTGCTGCTGATGCGTTAAATGATTTCTCATTATAGAAAATAATGT
AGTACTTTTATCTTAAATTT

Downstream 100 bases:

>100_bases
GAATTATTGGTAAAGCCATTCAGCCAAGTGATGCAGAAATTCAAGTAAATCCTCGTTCAAGAAGTGCCATATTACGTGTG
GCAGAGAGAATTTAGCGATG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNSENSFSSSEHITVLLHEAVNGLALKENGIYIDGTFGRGGHSRFILSQLSSNGRLIAVDRDPRAIAEAHKIQDLRFQIE
HNSFSHIPEICDKLNLVGKIDGILLDLGVSSPQLDEAERGFSFMKDGPLDMRMDTTQGLSAEEWLKQVSIEDLTWVLKTF
GEERFAKRIATAIVDFNKSAVKNGTEFLSRTSQLAELISQAVPFKDKHKHPATRSFQAIRIFINSELDELESLLNSALDM
LAPEGRLSIISFHSLEDRMVKHFMKNKVRARIFPKVYHCEKIKFSVIKN

Sequences:

>Translated_289_residues
MNSENSFSSSEHITVLLHEAVNGLALKENGIYIDGTFGRGGHSRFILSQLSSNGRLIAVDRDPRAIAEAHKIQDLRFQIE
HNSFSHIPEICDKLNLVGKIDGILLDLGVSSPQLDEAERGFSFMKDGPLDMRMDTTQGLSAEEWLKQVSIEDLTWVLKTF
GEERFAKRIATAIVDFNKSAVKNGTEFLSRTSQLAELISQAVPFKDKHKHPATRSFQAIRIFINSELDELESLLNSALDM
LAPEGRLSIISFHSLEDRMVKHFMKNKVRARIFPKVYHCEKIKFSVIKN
>Mature_289_residues
MNSENSFSSSEHITVLLHEAVNGLALKENGIYIDGTFGRGGHSRFILSQLSSNGRLIAVDRDPRAIAEAHKIQDLRFQIE
HNSFSHIPEICDKLNLVGKIDGILLDLGVSSPQLDEAERGFSFMKDGPLDMRMDTTQGLSAEEWLKQVSIEDLTWVLKTF
GEERFAKRIATAIVDFNKSAVKNGTEFLSRTSQLAELISQAVPFKDKHKHPATRSFQAIRIFINSELDELESLLNSALDM
LAPEGRLSIISFHSLEDRMVKHFMKNKVRARIFPKVYHCEKIKFSVIKN

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=269, Percent_Identity=41.2639405204461, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI165377202, Length=196, Percent_Identity=39.2857142857143, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI1786270, Length=264, Percent_Identity=63.6363636363636, Blast_Score=348, Evalue=2e-97,
Organism=Drosophila melanogaster, GI62472493, Length=278, Percent_Identity=38.4892086330935, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28571637, Length=278, Percent_Identity=38.4892086330935, Blast_Score=166, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 32640; Mature: 32640

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSENSFSSSEHITVLLHEAVNGLALKENGIYIDGTFGRGGHSRFILSQLSSNGRLIAVD
CCCCCCCCCCCCEEEEEEHHHCCEEEECCCEEEECCCCCCCCHHHHHHHHCCCCCEEEEC
RDPRAIAEAHKIQDLRFQIEHNSFSHIPEICDKLNLVGKIDGILLDLGVSSPQLDEAERG
CCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHC
FSFMKDGPLDMRMDTTQGLSAEEWLKQVSIEDLTWVLKTFGEERFAKRIATAIVDFNKSA
CHHHCCCCCCEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VKNGTEFLSRTSQLAELISQAVPFKDKHKHPATRSFQAIRIFINSELDELESLLNSALDM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LAPEGRLSIISFHSLEDRMVKHFMKNKVRARIFPKVYHCEKIKFSVIKN
HCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEECC
>Mature Secondary Structure
MNSENSFSSSEHITVLLHEAVNGLALKENGIYIDGTFGRGGHSRFILSQLSSNGRLIAVD
CCCCCCCCCCCCEEEEEEHHHCCEEEECCCEEEECCCCCCCCHHHHHHHHCCCCCEEEEC
RDPRAIAEAHKIQDLRFQIEHNSFSHIPEICDKLNLVGKIDGILLDLGVSSPQLDEAERG
CCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHC
FSFMKDGPLDMRMDTTQGLSAEEWLKQVSIEDLTWVLKTFGEERFAKRIATAIVDFNKSA
CHHHCCCCCCEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VKNGTEFLSRTSQLAELISQAVPFKDKHKHPATRSFQAIRIFINSELDELESLLNSALDM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LAPEGRLSIISFHSLEDRMVKHFMKNKVRARIFPKVYHCEKIKFSVIKN
HCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA